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*  Antibiotic - Wikipedia
Antibiotics are used to treat or prevent bacterial infections,[12] and sometimes protozoan infections. (Metronidazole is ... A few antibiotics have received marketing authorization in the last seven years. The cephalosporin ceftaroline and the ... include ceftazidime-avibactam and ceftolozane-avibactam for complicated urinary tract infection and intra-abdominal infection.[ ... Antibiotics are usually taken by mouth. In more severe cases, particularly deep-seated systemic infections, antibiotics can be ...
  https://en.m.wikipedia.org/wiki/Antibiotic
*  Practice Guidelines: Updated Guideline on Diagnosis and Treatment of Intra-Abdominal Infections - American Family Physician
Intra-abdominal infections are the second most common cause of infectious mortality in intensive care units. Complicated intra- ... abdominal infection, which extends into the peritoneal space, is associated with abscess formation and peritonitis. ... The Surgical Infection Society and Infectious Diseases Society of America recently updated recommendations for diagnosis and ... HEALTH CARE-ASSOCIATED INFECTION IN ADULTS. Empiric antibiotic therapy for health care-associated intra-abdominal infection ...
  https://www.aafp.org/afp/2010/0915/p694.html
*  Pseudomonas aeruginosa Infections Medication: Antibiotics
Single versus combined antibiotic therapy for gram-negative infections. Ann Pharmacother. 2004 Feb. 38(2):332-7. [Medline]. ... Pseudomonas infection can be treated with a combination of an antipseudomonal beta-lactam (eg, penicillin or cephalosporin) and ... Critical evaluation of ceftolozane-tazobactam for complicated urinary tract and intra-abdominal infections. Ther Clin Risk ... Pseudomonal infections are increasingly resistant to certain antibiotics, and the organism may acquire resistance during ...
  https://emedicine.medscape.com/article/226748-medication
*  Ceftolozane Sulfate and Tazobactam Sodium Monograph for Professionals - Drugs.com
Cephalosporins / beta-lactamase inhibitors. Related Drugs. Intraabdominal Infection ciprofloxacin, metronidazole, clindamycin, ... Antibacterial;1 β-lactam antibiotic;1 fixed combination of ceftolozane (a third generation cephalosporin) and tazobactam (a β- ... other β-lactam antibiotics, or other allergens.1 Importance of discontinuing the drug and immediately and informing clinician ... Intra-abdominal Infections. Treatment of complicated intra-abdominal infections caused by susceptible Enterobacter colacae, ...
  https://www.drugs.com/monograph/ceftolozane-sulfate-and-tazobactam-sodium.html
*  Ceftolozane - Wikipedia
Ceftolozane is a novel cephalosporin antibiotic, developed for the treatment of infections with gram-negative bacteria that ... have become resistant to conventional antibiotics. It was studied for urinary tract infections, intra-abdominal infections and ... is indicated for the treatment of complicated urinary tract infections and complicated intra abdominal infections. The in vitro ... "Cephalosporins currently in early clinical trials for the treatment of bacterial infections". Expert Opinion on Investigational ...
  https://en.wikipedia.org/wiki/Ceftolozane
*  Access to antibiotics: a safety and equity challenge for the next decade | Antimicrobial Resistance & Infection Control | Full...
The major driver of resistance is misuse of antibiotics in both human and non-human medicine. Both enhanced access and ... There is an urgent need for an international, integrated, multi-level action to preserve antibiotics in the armamentarium of ... Some microbial pathogens have become resistant to multiple antibiotics, if not all presently available, thus severely ... Bacterial resistance to antibiotics is increasing worldwide in healthcare settings and in the community. ...
  https://aricjournal.biomedcentral.com/articles/10.1186/2047-2994-2-1
*  Escherichia coli - Infectious Disease and Antimicrobial Agents
... bacteraemia and intra-abdominal infections (85). Risk factors associated with infections caused by CTX-M-producing E. coli ... The b-lactam antibiotics, especially the 3rd generation cephalosporins, and the fluroquinolones are the major drug classes used ... Treatment of infections due to multi-resistant E. coli. The presence of ESBLs and AmpC b-lactamases complicates antibiotic ... bloodstream infections, surgical site infections, pneumonia and sepsis (81).The cephalosporins, fluoroquinolones, and ...
  http://www.antimicrobe.org/b104.asp
*  Surkef 1000 mg Injection - Uses, Dosage, Side Effects, Composition & more | Practo
... gynecological infections including gonorrhea, intraabdominal infections, and septicemia caused by susceptible microorganisms. ... It is not recommended for use in patients who are allergic to cephalosporins or penicillins. Know Surkef 1000 mg Injection uses ... Surkef 1000 mg Injection is a third-generation cephalosporin antibiotic used in the treatment of infections of skin and skin ... Surkef 1000 mg Injection is a third-generation cephalosporin antibiotic used in the treatment of infections of skin and skin ...
  https://www.practo.com/medicine-info/surkef-1000-mg-injection-36475
*  Federal Register :: New Animal Drugs; Cephalosporin Drugs; Extralabel Animal Drug Use; Order of Prohibition
... is issuing an order prohibiting certain extralabel uses of cephalosporin antimicrobial drugs in certain food-producing animals ... These newer cephalosporins are the antibiotics of choice in the treatment of serious Salmonella and Shigella infections, ... intra-abdominal infections, pelvic inflammatory disease, and diabetic foot infections. Approved indications for newer ... and cephalosporins contribute 14 percent of the total outpatient antibiotic prescriptions. This use accounts for over 50 ...
  https://www.federalregister.gov/documents/2012/01/06/2012-35/new-animal-drugs-cephalosporin-drugs-extralabel-animal-drug-use-order-of-prohibition
*  Ceftazidime-avibactam: a novel cephalosporin/β-lactamase inhibitor | Review article | Salvadore- salvadore.info
The limited availability in treatment options for these infections prompted both the UK to create a five-year antimicrobial ... resistance strategic plan to stimulate the development of new antibiotics, and the Infectious Diseases Society of America to ... Over the past decade, infections caused by multidrug-resistant Gram-negative organisms have increased. ... Limited data from phase II and III clinical trials support its use for patients with complicated intra-abdominal infections and ...
  https://salvadore.info/research/ceftazidime-avibactam-a-novel-cephalosporin/-lactamase-inhibitor/20202413.article
*  Urgent Need for Antibiotics; Biotechs Carrying the Load | BioWorld
... complicated urinary tract infections (cUTI), and complicated intra-abdominal infections (cIAI). ... Twelve were dedicated to ceftolozane/tazobactam, its late-stage antibiotic candidate for gram-negative infections, Steve Gilman ... Ceftolozane is a cephalosporin with in vitro activity against multidrug-resistant Pseudomonas aeruginosa and most ... and our own late-stage antibiotic candidate for gram-negative infections ceftolozane/tazobactam that could be ready for NDA ...
  http://www.bioworld.com/content/urgent-need-antibiotics-biotechs-carrying-load
*  PPT - Carbapenem -resistant Enterobacteriaceae (CRE) and the Imperative for Antimicrobial Stewardship PowerPoint Presentation...
The clinical significance of beta lactam antibiotics*The beta lactam antibiotics comprise the penicillins, cephalosporins, ... Historically, these bacteria have been implicated in an array of human infection (UTI, nosocomial pneumonia, intra-abdominal ... Novel glycylcycline antibiotic. *Bacteriostatic, large volume of distribution (poor serum levels make it less than ideal for ... Infections due to CRE are associated with poor outcomes. *Risk factors for CRE include transplant history, LTAC stay, and ...
  https://www.slideserve.com/kylia/carbapenem-resistant-enterobacteriaceae-cre-and-the-imperative-for-antimicrobial-stewardship
*  Pfizer Completes Acquisition of Small Molecule Anti-Infective Business From AstraZeneca | WebWire
... complicated intra-abdominal infections; intra- and post-partum infections; complicated skin and soft tissue infections; and ... Indication: Zinforo was launched in October 2012 and is an intravenous cephalosporin antibiotic intended for use as a ... including those resistant to carbapenem antibiotics, one of the most significant unmet medical needs in bacterial infections ... In the U.S., Merrem is indicated as single agent therapy for the treatment of intra-abdominal infections and bacterial ...
  https://www.webwire.com/ViewPressRel.asp?aId=207010
*  Third-generation cephalosporin resistance of community-onset Escherichia coli and Klebsiella pneumoniae bacteremia in a...
3GC, third-generation cephalosporin; UTI, urinary tract infection; IAI, intra-abdominal infection; TMB-SMX, trimethoprim/ ... 3GC, third-generation cephalosporin.. aThree hundred eighty-one patients with data of previous antibiotics use were included in ... and prior antibiotic use is an independent risk factor. Carbapenem should be considered an empirical antibiotic for patients ... The most common infections were urinary tract (43.1%) infections, followed by intra-abdominal (39.0%), lower respiratory tract ...
  http://www.kjim.org/journal/view.php?number=169169
*  Antituberculosis Drugs Manufacturer,Antituberculosis Drugs Exporter From India
... female genital tract and urinary tract infections. This medicine belongs to a class of drugs known as cephalosporin antibiotics ... urinary tract infections, intra- -abdominal infections, pelvic inflammatory disease and septicemia. It is basically a ... Basically a semisynthetic, sterile, beta- lactamase resistant, broad- spectrum cephalosporin antibiotic, it is meant only for ... lower respiratory tract infections, pelvic inflammatory disease, intra- -abdominal infections and septicemia. ...
  http://www.unitedbiotechindia.net/antituberculosis-drugs.html
*  Antibiotics | allnurses
... antibiotics review antibiotics review overview: choosing an antibacterial agent can be challenging, given the wide array of ... followed by 50 mg twice daily in patients with complicated skin and skin structure infections and intra-abdominal infections. ... in addition, it is easier to quickly grasp the strengths and weaknesses of a newly marketed antibiotic if you understand the ... ceftobiprole. ceftobiprole is a novel broad-spectrum cephalosporin with potent bactericidal activities against mrsa and ...
  https://allnurses.com/nursing-patient-medications/antibiotics-197106.html
*  New combination antibiotic for serious infections | MIMS online
... is a new combination antibiotic for the treatment of serious Gram-negative bacterial infections requiring hospitalisation. ... Zavicefta is given by intravenous infusion to treat complicated intra-abdominal infections, complicated urinary tract ... Zavicefta has been developed in response to the urgent need for new antibiotics to treat serious infections that are becoming ... Ceftazidime is an established third-generation cephalosporin. The addition of avibactam protects ceftazidime against ...
  https://www.mims.co.uk/new-combination-antibiotic-serious-infections/infections-and-infestations/article/1427045
*  Intra-abdominal infection - The Clinical Advisor
"Management of intra-abdominal infections. The case for intraoperative cultures and comprehensive broad spectrum antibiotic ... Alternatively, a combination system of a cephalosporin or aztreonam or a fluoroquinolone + metronidazole also provide adequate ... First line management includes either oral metronidazole or oral vancomycin coupled with cessation of unecessary antibiotics. ... Peritonitis, intra-abdominal abscess, intra-abdominal sepsis, complicated- and uncomplicated intra-abdominal infection ...
  http://www.clinicaladvisor.com/critical-care-medicine/intra-abdominal-infection/article/586933/
*  Cefotan - FDA prescribing information, side effects and uses
second generation cephalosporins cefuroxime, Ceftin, cefaclor, cefprozil, cefoxitin. Bacterial Infection ciprofloxacin, ... Diarrhea is a common problem caused by antibiotics which usually ends when the antibiotic is discontinued. Sometimes after ... Intra-abdominal lnfections caused by E. coli, Klebsiella species (including K. pneumoniae), Streptococcus species, Bacteroides ... The dosage recommended in the labeling of both antibiotics may be given and depends on the severity of the infection and the ...
  https://www.drugs.com/pro/cefotan.html
*  Cefminox - Wikipedia
Cephalosporin antibiotics. *Tetrazoles. *Antibiotic stubs. Hidden categories: *Template:drugs.com link with non-standard ... "Cefminox versus metronidazole plus gentamicin intra-abdominal infections: A prospective randomized controlled clinical trial". ... is a second-generation cephalosporin antibiotic.[1][2] Spectrum[edit]. Cefminox is a broad-spectrum, bactericidal cephalosporin ... This systemic antibiotic-related article is a stub. You can help Wikipedia by expanding it.. *v ...
  https://en.wikipedia.org/wiki/Cefminox
*  Antibiotic Therapy for Appendicitis in Children
Aminoglycosides: These antibiotics are employed primarily to treat gram-negative infections. They bind to the 30S and 50S ... A single antibiotic is sufficient for a nonperforated appendicitis. Second- or third-generation cephalosporins such as ... 5 Percutaneous drainage may be required in patients who develop an intra-abdominal abcess.22 ... Antibiotic therapy is an important aspect of the management of ruptured (perforated) appendicitis.20 IV antibiotics that are ...
  https://www.uspharmacist.com/article/antibiotic-therapy-for-appendicitis-in-children
*  Broad-spectrum antibiotics - Renal and Urology News
... was FDA-approved in 2007 for the treatment of complicated intra-abdominal infections and complicated urinary tract infections ... Antibiotics associated with MDROs. Decreased use of the following antibiotics or antibiotic classes may be associated with a ... 3rd-generation cephalosporins: extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae, cephalosporin-resistant ... Which broad-spectrum antibiotics play a key role in the prevention and control of health care-associated infections?. No broad- ...
  https://www.renalandurologynews.com/hospital-infection-control/broad-spectrum-antibiotics/article/598530/
*  Carbapenem - Wikipedia
"Diagnosis and management of complicated intra-abdominal infection in adults and children: guidelines by the Surgical Infection ... Like the penicillins and cephalosporins, they are members of the beta lactam class of antibiotics, which kill bacteria by ... Further, the porin levels may be down-regulated in response to antibiotic exposure. Antibiotic molecule that successfully ... "Diagnosis and management of complicated intra-abdominal infection in adults and children: guidelines by the Surgical Infection ...
  https://en.wikipedia.org/wiki/Carbapenem
*  Prevention of Infective Endocarditis | Circulation
These microorganisms may cause intra-abdominal infection or infection of the hepatobiliary system. Such infections are often ... A first-generation cephalosporin is most often used, but the choice of an antibiotic should be influenced by the antibiotic ... Patients Already Receiving Antibiotics. If a patient is already receiving long-term antibiotic therapy with an antibiotic that ... antibiotic prophylaxis. Infective endocarditis (IE) is an uncommon but life-threatening infection. Despite advances in ...
  http://circ.ahajournals.org/content/116/15/1736.full
*  Ceftriaxone - Wikipedia
Ceftriaxone is a third-generation antibiotic from the cephalosporin family of antibiotics. It is within β {\displaystyle \beta ... bone and joint infections, intra-abdominal infections, skin infections, urinary tract infections, gonorrhea, and pelvic ... is an antibiotic useful for the treatment of a number of bacterial infections. This includes middle ear infections, ... lower respiratory tract infections acute bacterial otitis media skin and skin structure infections urinary tract infections ...
  https://en.wikipedia.org/wiki/Ceftriaxone