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*  Allergy and Hay Fever Medication Treatments & Symptoms
Histamine is a chemical released by specialized allergy cells called activated mast cells during the allergic response. By ... occupying the histamine receptor sites, they prevent histamine from causing the characteristic allergic symptoms. ... How mast cell inhibitors work: These drugs prevent the release of histamine and other chemicals that cause allergic symptoms ... resulting in activation of cells in the body called mast cells and basophils. These cells release chemical messengers in the ...
  https://www.emedicinehealth.com/understanding_allergy_and_hay_fever_medications/article_em.htm
*  Xinzhong Dong Reports in Nature the Identification of a New Mast Cell Allergy Receptor - The Solomon H Snyder Department of...
Mast cells are primary effectors in allergic reactions, and may have important roles in disease by secreting histamine and ... This receptor is exclusively found in a type of immune cells called mast cells. Once the receptor is triggered, it causes mast ... Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions. McNeil et al, Nature (2014) doi: ... reports in Nature the identification of a new receptor on mast cells linked to drug-induced allergic reactions. Many clinical ...
  http://neuroscience.jhu.edu/news/35
*  Livostin nasal spray (discontinued in the UK - July 2005)
Histamine is a substance produced by the body as part of its defence mechanisms. It is stored in cells called mast cells, in ... The released histamine then binds to its receptors (H-1 receptors), causing a chain reaction that results in allergic symptoms ... Levocabastine works by blocking histamine receptors. It does not prevent the actual release of histamine from mast cells, but ... It does not prevent the actual release of histamine from mast cells, but prevents it binding to its receptors. This in turn ...
  http://www.netdoctor.co.uk/medicines/allergy-and-asthma/a7021/livostin-nasal-spray-discontinued-in-the-uk-july-2005/
*  ISTA Pharmaceuticals Announces Statistically Significant,Preliminary Results From its U.S. Phase II/III Clinical Study Of...
... highly selective antagonist of the histamine 1 (H1) receptor, it has a stabilizing effect on mast cells, and it suppresses the ... The access code for the live call is 49242638. To access the 24-hour audio replay, U.S. and Canadian participants may dial 888- ... Bepotastine was approved in Japan for use as a systemic drug in the treatment of allergic rhinitis and urticaria/pruritus in ... ISTA will host a conference call with a simultaneous webcast today, May 8, 2007 at 10:30 AM Eastern Time to discuss today's ...
  http://www.bio-medicine.org/medicine-technology/ISTA-Pharmaceuticals-Announces-Statistically-Significant-0APreliminary-Results-From-its-U-S--Phase-II-III-Clinical-Study-Of-0ABepotastine-762-1/
*  flare ups in endodontics -1 etiological factors | Inflammation | Immune System
IgE can bind to receptors on tissue mast cells and basophils, causing degranulation of these cells with release of mediators, ... and some lymphocyte products called lymphokines, all of which are capable of causing pain. Histamine is normally stored in the ... When these cells are activated by IgE, PGD2 participates in allergic responses. It is also a potent inhibitor of platelet ... PGD2 is produced by basophils and mast cells. It is the principal metabolite of arachidonic acid in mast cells. ...
  https://www.scribd.com/document/29924342/flare-ups-in-endodontics-1-etiological-factors
*  Experimental therapy stops allergic reactio...( The other receptor molecule is like a b...)
In laboratory tests on human mast cells and basophils the higher the ...Although many more lab and animal studies will be ... necessary before thi...GE2 is called a fusion protein because its two active parts are connec......,Experimental,therapy,stops, ... allergic,reactions,in,mice,biological,biology news articles,biology news today,latest biology news,current biology news,biology ... The other receptor molecule is like a brake explains senior author An... ...
  http://news.bio-medicine.org/biology-news-2/Experimental-therapy-stops-allergic-reactions-in-mice-7701-2/
*  Allergies - Tr‚Äčevor H. Kaye, MD
Antihistamines block the histamine receptor on mast cells, which are the main culprits in allergic reactions. They are very ... Another newer class of drugs, called anti-leukotrienes, targets another substance involved in allergic responses. Mast cell ... The antibodies attach themselves to mast cells in the bloodstream, which release histamines and other inflammatory chemicals ... People who develop allergic rhinitis have an excess of a certain class of antibodies, called IgE, which makes them unusually ...
  https://trevorkaye.weebly.com/allergies.html
*  Google Answers: High Histamine Levels
Histamine is released from histamine-storing cells (mast cells) and then attaches to other cells that have receptors for ... So called 'antihistamines' like Benadryl only work to block some of your body's histamine receptors (relieving some histamine ... In extreme cases, histamine levels in someone who is allergic to a bee sting or a particular food like strawberries can be ... Benadryl and other over the counter anti-histamines are often used when histamine is released by mast cells (specialized white ...
  http://answers.google.com/answers/threadview?id=470861
*  Antihistamines - American Osteopathic College of Dermatology (AOCD)
... glandular cells, and mast cells. Since histamines causes vasodilation and increase vascular permeability which causes fluid to ... There are two subtypes of antihistamines called H1-receptor antagonists and H2-receptor antagonists. H1-antihistamines are used ... Uses: The H1-antihistamines are used to treat allergic symptoms such as hives, itchy skin, itchy eyes, runny nose, and sneezing ... The H2-antihistamines block H2 histamine receptors that are found in the gastric acid producing parietal cells of the stomach. ...
  http://www.aocd.org/page/Antihistamines/Antihistamines.htm
*  Comparison Essay Sample: Drug Comparison | EssaysProfessors.com
... by chemical called histamine which is released by mast cells and then it attaches the cells which have receptors for histamine ... The drug is available in 10 mg tablets and also syrup of 5mg/5 ml/. The drug can also be used to treat patients with allergic ... What Claritin does is to block one type of receptor, H1 receptor, so that the cells that have H1 receptors are not activated. ... The chemical then stimulates the cells to produce effects that we normally associate them with allergy. ...
  https://essaysprofessors.com/samples/comparison/drug-comparison.html
*  Histamine - Wikipedia
Most histamine in the body is generated in granules in mast cells and in white blood cells (leukocytes) called basophils. Mast ... allergic rhinitis) Histamine intolerance Histamine receptor antagonist Red wine headache Scombroid food poisoning Histamine ... The most important pathophysiologic mechanism of mast cell and basophil histamine release is immunologic. These cells, if ... release histamine that stimulates nearby parietal cells by binding to the apical H2 receptor. Stimulation of the parietal cell ...
  https://en.wikipedia.org/wiki/Histamine
*  Cytotoxic anaphylaxis | definition of cytotoxic anaphylaxis by Medical dictionary
Release is a consequence of the binding of IgE antibodies to Fc receptors on the surface of particularly mast cells and ... Called also anaphylactic shock.. Substances most likely to produce anaphylaxis include drugs, particularly antibiotics and ... an unusual or exaggerated allergic reaction of an animal to foreign protein or other substances. Anaphylaxis is an immediate or ... antibody-mediated hypersensitivity reaction (type I) produced by the release of vasoactive agents such as histamine and ...
  https://medical-dictionary.thefreedictionary.com/cytotoxic+anaphylaxis
*  Why do red lines appear on the body after scratching?
Histamine is released from cells called mast cells that lie along the blood vessels in the skin. Allergic reactions, chemicals ... Antihistamines, primarily those working on H1 receptors, are the first line of therapy for urticaria. H2 antihistamines, such ... This is caused by the release of a chemical called histamine. ... What is the normal range of pus cells in the urine of children? ... Hives that form after firmly stroking or scratching the skin are called dermatographism. It affects about 5 per cent of the ...
  https://doctor.ndtv.com/faq/why-do-red-lines-appear-on-the-body-after-scratching-4351
*  'Nano-keys' bind cell receptors and trigger allergic reactions ( The tumblers of life continue to click .....
By understanding a membrane's role in cell function she explained tha...,'Nano-keys',bind,cell,receptors,and,trigger,allergic, ... How cell membranes control cellular function has long been studied but...Barbara Baird Cornell professor of chemistry and ... Baird and her colleagues chose to work with mast cells. They were chosen because mast cells secrete chemicals and histamines ( ... The so-called nano-keys are surfaces of silicon with a layer of polymer or a thin lipid (fatty molecules that make up cell ...
  http://www.bio-medicine.org/biology-news/Nano-keys-bind-cell-receptors-and-trigger-allergic-reactions-2464-1/
*  Dermatographic urticaria - Wikipedia
Symptoms are thought to be the result of histamine being released by mast cells on the surface of the skin. Due to the lack of ... In rare cases, allergy tests may uncover substances the patient is allergic to. While cromoglycate, which prevents histamine ... These may need to be given as a combination of H1 antagonists, or possibly with an H2-receptor antagonist such as cimetidine. ... it may be a condition called shower eczema. If it affects mainly the head, it may be psoriasis. ...
  https://en.wikipedia.org/wiki/Dermatographic_urticaria
*  New treatment for allergic response targets mast cells | EurekAlert! Science News
National Institutes of Health have developed a method that stops allergic reactions by removing a key receptor from mast cells ... stimulating the mast cells and basophils to release mediators, such as histamine, that trigger an allergic response. ... Cruse and Metcalfe looked at a gene called MS4A2, which is only expressed in mast cells and basophils, and is responsible for ... IMAGE: Left: mast cells are activated by allergens reacting with IgE bound to IgE receptors on the mast cell surface to trigger ...
  https://www.eurekalert.org/pub_releases/2016-11/ncsu-ntf111816.php
*  Allergy Tests | definition of Allergy Tests by Medical dictionary
Histamine - A chemical released by mast cells that activates pain receptors and causes cells to become leaky. ... displays a type of antibody called immunoglobulin type E (IgE) on its cell surface, and participates in the allergic response ... Allergic reactions involve a special set of cells in the immune system known as mast cells. Mast cells serve as guards in the ... Mast cells display a special type of antibody, called immunoglobulin type E (IgE), on their surface. Inside, mast cells store ...
  https://medical-dictionary.thefreedictionary.com/Allergy+Tests
*  JenKuz - Celiac.com Celiac Disease & Gluten-Free Diet Forum
... are mediated by IgE resulting in histamine release from basophils and mast cells. Eosinophils relaease "granules" that mediate ... they release histamine. They have the most receptors for IgE but also have receptors for IgA. Because they are evolutionarily ... How the eosinophils get called to the esophagus or gut in high numbers is an open question....My guess is that given the ... Ordinarily, eosinophilia is associated with "genuine" allergic responses, wchich, by definition, ...
  https://www.celiac.com/gluten-free/profile/11019-jenkuz/?tab=topics
*  Granulocyte - Wikipedia
... and allergic reactions, particularly anaphylaxis. Mast cells are also involved in mediating inflammation and autoimmunity as ... Basophils have receptors that can bind to IgE, IgG, complement, and histamine. The cytoplasm of basophils contains a varied ... they are involved in the destruction of tumor cells, and they promote the repair of damaged tissue. A polypeptide called ... they regulate other immune cell functions (e.g., CD4+ T cell, dendritic cell, B cell, mast cell, neutrophil, and basophil ...
  https://en.wikipedia.org/wiki/Granulocyte
*  immunoglobulin facts, information, pictures | Encyclopedia.com articles about immunoglobulin
It binds to mast cells, and when triggered by the presence of antigen causes histamine release and hence inflammation and other ... They are produced by specialized white blood cells called B cells and are present in blood serum and other body fluids. An ... It acts in conjunction with IgM as an antigen receptor. Immunoglobulin E (IgE) also normally has very low concentrations in ... blood and connective tissues, but it plays a crucial role in allergic reactions. ...
  https://www.encyclopedia.com/science-and-technology/biochemistry/biochemistry/immunoglobulin
*  Cromoglicic acid - Wikipedia
This drug prevents the release of inflammatory chemicals such as histamine from mast cells. Because of their convenience (and ... "Topical antihistamines and mast cell stabilisers for treating seasonal and perennial allergic conjunctivitis". Cochrane ... After several years of trial he isolated an effective and safe asthma-preventing compound called cromolyn sodium. Cromoglicic ... exaggerated neuronal reflexes triggered by stimulation of irritant receptors on sensory nerve endings (e.g. exercise-induced ...
  https://en.wikipedia.org/wiki/Cromoglicic_acid
*  H1 antagonist - Wikipedia
... from the mast cell or basophil. Once released, the histamine can react with local or widespread tissues through histamine ... H1 antagonists, also called H1 blockers, are a class of medications that block the action of histamine at the H1 receptor, ... at the histamine H1-receptor. In type I hypersensitivity allergic reactions, an allergen (a type of antigen) interacts with and ... Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell ...
  https://en.wikipedia.org/wiki/H1_antagonist
*  Olopatadine - Wikipedia
Olopatadine acts as a selective antagonist of the histamine H1 receptor, thus stabilizing mast cells and inhibiting histamine ... also called Opatanol in some countries; Olopat in India). It is used to treat itching associated with allergic conjunctivitis ( ... "Topical antihistamines and mast cell stabilisers for treating seasonal and perennial allergic conjunctivitis". Cochrane ... Olopatadine is an antihistamine (as well as anticholinergic and mast cell stabilizer), sold as a prescription eye drop ...
  https://en.wikipedia.org/wiki/Olopatadine
*  Child Allergy Treatment - Menu Allergie
... then to some receptor on mast cells or basophils where by it triggers the release of inflammatory chemicals such as histamine. ... For the critical allergic reaction (anaphylaxis), simply call 911 or your neighborhood emergency number or seek out emergency ... Call the doctor who prescribed it right away if you have symptoms after starting a new medication. ... Allergies, generally known as allergic ailments, certainly are a range of disorders induced by hypersensitivity in the immune ...
  http://menuallergie.net/child-allergy-treatment/
*  Hay Fever Guide: What is Hayfever?
Hay fever or seasonal allergic rhinitis is an allergic reaction to pollen and other airborne allergens such as fungal spores. ... Hay fever is an allergic reaction to pollen in the air. The body contains antibodies called Immunoglobulin E (IgE). Mast cells ... When enough of these are so linked, the mast cells will then release histamines. The body needs histamines - in the brain they ... have special receptors to which IgE can bind. When two of these mast cell bound antibodies are together the allergen is ...
  https://haymax.biz/what-is-hay-fever/