*  Frontiers | The emergence of Pax7-expressing muscle stem cells during vertebrate head muscle development | Frontiers in Aging...
Currently, the in vitro manipulation and culture of these cells is still in its infancy, yet muscle stem cells may be the most ... Currently, the in vitro manipulation and culture of these cells is still in its infancy, yet muscle stem cells may be the most ... Unlike trunk muscle stem cells, head muscle stem cells do not have a previous history of Pax7 expression, instead Pax7 ... Unlike trunk muscle stem cells, head muscle stem cells do not have a previous history of Pax7 expression, instead Pax7 ...
  https://www.frontiersin.org/articles/10.3389/fnagi.2015.00062/full
*  Evaluation of the neuropeptide expression profile in the trigeminal ganglia after corneal herpes simplex virus 1 infection in...
Flow cytometry of NK1R KO mouse TGs at 5 day p.i showed an increased frequency of CD4 and CD8 T cells compared to B6 mice. ... infection leads to retrograde transport of the virus to the trigeminal ganglia (TG). As a result, immune cells infiltrate the ... Evaluation of the neuropeptide expression profile in the trigeminal ganglia after corneal herpes simplex virus 1 infection in ... Evaluation of the neuropeptide expression profile in the trigeminal ganglia after corneal herpes simplex virus 1 infection in ...
  http://iovs.arvojournals.org/article.aspx?articleid=2640891
*  Chromatolysis - Wikipedia
Examination of the trigeminal and dorsal root ganglia revealed peripheral chromatolysis in these cells. The cells exhibited ... for the 6 and 12 days groups respectively. For the purposes of the study A-cells were defined as ganglia neurons whose ... It is an induced response of the cell usually triggered by axotomy, ischemia, toxicity to the cell, cell exhaustion, virus ... and B-cell perikarya of their L5 dorsal root ganglion were examined. There was no morphological change in the B-cell perikarya ...
  https://en.wikipedia.org/wiki/Chromatolysis
*  Epitope specificity of CD8+ T cells in HSV-1 latently infected mouse trigeminal ganglia | IOVS | ARVO Journals
20% of HSV-specific CD8 T cells in day 14 TG but all of those in day 34 TG produced IFN-g. The CD8+ T cells that prevent HSV-1 ... RL Hendricks, KM Khanna; Epitope specificity of CD8+ T cells in HSV-1 latently infected mouse trigeminal ganglia . Invest. ... Epitope specificity of CD8+ T cells in HSV-1 latently infected mouse trigeminal ganglia ... Epitope specificity of CD8+ T cells in HSV-1 latently infected mouse trigeminal ganglia ...
  http://iovs.arvojournals.org/article.aspx?articleid=2421097
*  "Analysis of Bovine Herpesvirus 1 Transcripts during a Primary Infectio" by Luis M. Schang and Clinton J. Jones
Although the same cascade is assumed to occur during an infection of neurons in trigeminal ganglia (TG) of cattle, no ... IE transcripts were detected before E or L RNAs when rabbit kidney cells were infected with a low multiplicity of infection and ... Consequently, we analyzed BHV-1 gene expression in bovine TG at 1, 2, 4, 7, and 15 days postinfection (dpi). Infectious virus ... These studies suggested that expression of full-length and polyadenylated IE transcripts in trigeminal ganglia was not ...
  https://digitalcommons.unl.edu/vetscipapers/47/
*  In Herpetic Cornea, Inflammatory Cytokines Predominate, While Th1 Cytokines Hold Virus Spread in the Trigeminal Ganglion |...
Virus titer was maximum at 4 days PI in the cornea and at 5 days PI in the trigeminal ganglion. Stromal opacities appeared at 2 ... inflammatory cytokines were predominent and were responsible for cell infiltrations and corneal opacities. By contrast, Th1 ... while in the trigeminal ganglion, Th1 type cytokines (IL-2, IFN-gamma and IL-12) were preeminent at 4-8 days PI and 12 days PI ... The results were superimposed on the clinical scores and virus titers for corneas and trigeminal ganglia. Results: In the ...
  http://iovs.arvojournals.org/article.aspx?articleid=2417621
*  "Regulation of Neuropeptide Y, Vasoactive Intestinal Polypeptide, and T" by Debra D. DeLoach
Trigeminal ganglia were dissected after 1, 3, and 5 days after CFA-treatment. NPY expression was observed in Day 1 and Day 5 ... VIP expression was observed in Day 1 and Day 5 tissues, with localization to glial cells, and to both neurons and glial cell, ... and their receptors in mediating neuronal and glial cell activation in trigeminal ganglion that is likely to contribute to TMJ ... and to both neurons and glial cells, respectively. NPY receptor, NPY Y₂ was upregulated in Day 1 tissues, localized to neurons ...
  https://bearworks.missouristate.edu/theses/1262/
*  Human Fetal Keratocytes Have Multipotent Characteristics in the Developing Avian Embryo
However, they failed to form neurons despite their presence in the condensing trigeminal ganglion. These results show that HFKs ... The human cornea contains stem cells that can be induced to express markers consistent with multipotency in cell culture; ... into the cranial mesenchyme adjacent to the neural tube and the periocular mesenchyme in chick embryos at embryonic days 1.5 ... The HuNu-positive cells transformed into neural crest derivatives such as smooth muscle in cranial blood vessels, stromal ...
  https://scholarship.rice.edu/handle/1911/75339
*  Role of M1 and M2 macrophages in herpes simplex virus-1 infectivity in vitro and in vivo | IOVS | ARVO Journals
Virus replication in the eye and the level of latency in the trigeminal ganglia (TG) of the infected mice were determined on ... Luminex assay was performed to measure the changes in the profile of cytokine/chemokine produced in the infected cells. In ... day 28 post infection. Results : Plaque assay results showed that HSV-1 infectivity was dramatically decreased in the M1 ...
  http://iovs.arvojournals.org/article.aspx?articleid=2640883
*  HSV, latency, and T cells
In early days, it was tentatively believed that (3) was not likely -- you'd need to have some signal to draw the immune ... 2007). Selective retention of herpes simplex virus-specific T cells in latently infected human trigeminal ganglia. Proc Natl ... In early days, it was tentatively believed that (3) was not likely - you'd need to have some signal to draw the immune response ... Chronic inflammation means there are immune cells hanging around inside the ganglia. What are these cells? Are they specific ...
  http://www.iayork.com/MysteryRays/2007/10/18/hsv-latency-and-t-cells/
*  Kcnk18 - Potassium channel subfamily K member 18 - Mus musculus (Mouse) - Kcnk18 gene & protein
... trigeminal ganglion and dorsal root ganglia from E15.5 and increased through E18 to reach a peak in newborn mouse postnatal day ... Cell membrane 1 Publication. ,p>Manually curated information for which there is published experimental evidence.,/p> ,p>,a href ... High expression in trigeminal ganglion, also expressed in autonomic nervous system ganglia such as the stellate ganglion and ... Cell membrane, Membrane. ,p>This section provides information on the disease(s) and phenotype(s) associated with a protein.,p>, ...
  http://www.uniprot.org/uniprot/Q6VV64
*  Coiled-coil domain-containing 37 (FLJ40083) - Wikipedia
Between 20-30 days after birth in mus musculus, CCDC37 expression increases from less than 50% to about 85%. In rattus ... Most areas that express CCDC37 have an expression level of 20-40%. Expression levels in the trigeminal nerve, testis, medial ... Cell Biol. 107 (3): 841-9. Analysis and prediction of leucine-rich nuclear export signals Tanja la Cour, Lars Kiemer, Anne ... olfactory epithelium, dorsal root ganglia, and trachea are the highest with almost 75% expression. CCDC37 is expressed in the ...
  https://en.wikipedia.org/wiki/Coiled-coil_domain-containing_37_(FLJ40083)
*  Herpes labialis - Wikipedia
Inflammation (day 1): Virus begins reproducing and infecting cells at the end of the nerve. The healthy cells react to the ... the viruses move to sensory nerve ganglia (trigeminal ganglion), where they reside as lifelong, latent viruses. Asymptomatic ... Post-scab (12-14 days): A reddish area may linger at the site of viral infection as the destroyed cells are regenerated. Virus ... Pre-sore (day 2-3): This stage is defined by the appearance of tiny, hard, inflamed papules and vesicles that may itch and are ...
  https://en.wikipedia.org/wiki/Herpes_labialis
*  Oral Manifestations of HIV
Following the primary episode, the virus becomes latent in the trigeminal ganglion. Recurrent oral herpes occurs at any age ... Cells are enlarged; some contain enlarged ballooning cells with pyknotic nuclei. Some contain perinuclear haloes. ... prednisone 40 to 60 mg/day for 7 to 10 days) has been reported as helpful.(82) The risks of steroid therapy, however, must be ... the lymphocytic infiltrate is predominantly CD8 cells, unlike that in Sjogren's syndrome, which is predominantly CD4 cells.(76 ...
  http://hivinsite.ucsf.edu/InSite?page=kb-04-01-14
*  Critical Role of MicroRNA-155 in Herpes Simplex Encephalitis | The Journal of Immunology
Preparation of trigeminal ganglia single-cell suspensions.. At 14 d after HSV-1 RE ocular infection, mice were anesthetized and ... PLNs were collected at day 5 p.i., and aliquots of single-cell suspensions were stained for cell-surface markers CD8 and Kb-gB ... CD8 T cells are required to contain HSV replication in ganglia, and they orchestrate this response largely by IFN-γ production ... One aliquot was left unmanipulated, and the other aliquot received 1 × 105 CD8 T cells isolated at day 8 p.i. from lymph nodes ...
  http://www.jimmunol.org/content/192/6/2734
*  Plus it
Expression was highest at the interface between the ganglion cell layer and cytoblast layer. The ganglion cells were also Nogo- ... Nogo-A/B was also detected at high levels in peripheral ganglia other than DRG, e.g., the trigeminal ganglion (Fig. 3 C,D). ... The day of vaginal plug detection was considered embryonic day 1 (E1). Pregnant females were decapitated, and the embryos (E14 ... 7 C, inset). Once the granule cells had migrated past the Purkinje cells to their final position in the granule cell layer, ...
  http://www.jneurosci.org/content/22/9/3553
*  Viruses | Free Full-Text | The Role of the CoREST/REST Repressor Complex in Herpes Simplex Virus 1 Productive Infection and in...
The primary function of the HCLR complex is to silence neuronal genes in non-neuronal cells. HCLR plays a role in regulating ... The model we have chosen to resolve these questions are organ cultures of trigeminal ganglia harvested 30 days after corneal ... Cell 2006, 23, 377-387. [Google Scholar] [CrossRef]. *Ballas, N.; Grunseich, C.; Lu, D.D.; Speh, J.C.; Mandel, G. REST and its ... The trigeminal ganglia were harvested at frequent intervals during the first two weeks and at the end of the test period (28-30 ...
  http://mdpi.com/1999-4915/5/5/1208/htm
*  Pulpitis - Wikipedia
Substance P (SP) is a neuropeptide produced by capsaicin neuron cell bodies (localized in trigeminal ganglia and dorsal root) ... This neural growth typically lasts few a few days and function and form is retained. Thus, pain is poorly localized, and the ... innate immune cells, including immature dendritic cells (DCs), natural killer (NK) cells, and T cells, as well as (5) their ... B cells and T cells are the major lymphocytes involved. A variety of cytokines have been observed in the pulp. Patients with ...
  https://en.wikipedia.org/wiki/Pulpitis
*  Role of Tim-3/Galectin-9 Inhibitory Interaction In Viral Induced Immunopathology: Shifting The Balance Towards Regulators
... the corneas and trigeminal ganglia were disrupted by grinding with a syringe plunger on a cell strainer and a single-cell ... After 5 days, cells were characterized phenotypically by flow cytometry.. For the differentiation of CD4+ T cells into Th17 ... 5G, CFSE dilution in Foxp3+ cells TCR stimulated for 3 days, in the presence of IL-2 was greater in the cell population from ... The pattern was similar on day 15 but by day 40 had declined markedly. Analysis of lymph node and spleen cells at the time of ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC3891207/?lang=en-ca
*  PLEASE! Herpes on buttocks - Herpes Message Board - HealthBoards
HSV hides in nerve cell ganglion and I've been doing research on this too. They say it 'hides' in the sacral (base of spine) ... ganglion for genitally expressed HSV (1 or 2) and trigeminal (top of spine) ganglion for facial lesions. Well, this is 'in ... I find a new batch every few days and they last 6 or 7 weeks!. OK, now I was wondering why my outbreak areas are changing/ ... it stays in the ganglion where it was first introduced. I believe that the only way it gets into any other nerve ganglion is ...
  https://www.healthboards.com/boards/herpes/782512-please-herpes-buttocks.html
*  Canine herpesvirus - Wikipedia
The site of latency has been shown to be the trigeminal ganglion and possibly the lumbosacral ganglion. In adult dogs, the ... The incubation period of CHV is six to ten days. CHV is transmitted to puppies in the birth canal and by contact with infected ... The virus replicates in the surface cells of the nasal mucosa, tonsils, and pharynx. Low body temperature allows the virus to ... and death usually occurs in one to two days. In puppies three to five weeks old, the disease is less severe due to their ...
  https://en.wikipedia.org/wiki/Canine_herpesvirus
*  Imaging of viral neuroinvasion in the zebrafish reveals that Sindbis and chikungunya viruses favour different entry routes |...
Infected cells are in the trigeminal ganglion (TG); the axon-rich region visible behind (light blue dotted line) is the ... for 5 days at room temperature. Samples were washed for 2 days in PBSt and stained with 1 µM DiIC18(3) solution (DiI Stain; ... In the case of SINV infection, we sometimes observed infection of peripheral neurons, such as trigeminal ganglion (TG) cells ( ... 2014). Single-cell phenotyping within transparent intact tissue through whole-body clearing. Cell 158, 945-958. doi:10.1016/j. ...
  http://dmm.biologists.org/content/10/7/847.long
*  The Polymodal Ion Channel Transient Receptor Potential Vanilloid 4 Modulates Calcium Flux, Spiking Rate, and Apoptosis of Mouse...
C, TRPV4 antibody recognized a major 105 kDa band in TRPV4-expressing HEK293 cell cultures and trigeminal ganglion tissue; no ... RT-PCR was performed using total RNA extracted from adult (postnatal day 90) mouse retinas. Gel analysis revealed PCR products ... a ganglion cell-specific protein in ganglion cell somata. Additional TRPV4-IR is seen in a ganglion cell dendrite (arrow) and ... a ganglion cell specific protein. Colocalization is seen both in the ganglion cell bodies (yellow) and in a ganglion cell ...
  http://www.jneurosci.org/content/31/19/7089
*  Tcf7l1 protects the anterior neural fold from adopting the neural crest fate | Development
... cells (Fig. 4F). One day later at E9.5, we observed only a thin layer of Sox9+ cells between the N-cadherin+ forebrain tissue ... V, trigeminal ganglion. See also Fig. S2.. Sox10 mRNA expression was delayed in the absence of Tcf7l1, as it was barely ... 2005). Neural crest stem cell maintenance by combinatorial Wnt and BMP signaling. J. Cell Biol. 169, 309-320. doi:10.1083/jcb. ... NC cells are normally generated in the posterior neural plate border, whereas the anterior neural fold is devoid of NC cells. ...
  http://dev.biologists.org/content/143/12/2206.long
*  Ramsay Hunt syndrome type 2 - Wikipedia
... is a disorder that is caused by the reactivation of varicella zoster virus in the geniculate ganglion, a nerve cell bundle of ... Involvement of the trigeminal nerve can cause numbness of the face. Ramsay Hunt syndrome type 2 refers to shingles of the ... Treatment with the steroid prednisone and the antiviral drug acyclovir 800mg 5 times a day is controversial, with some studies ... the virus travels to the end of the nerve cell, where it causes the symptoms described above. The affected ganglion is ...
  https://en.wikipedia.org/wiki/Ramsay_Hunt_syndrome_type_2