Characterization, recellularization, and transplantation of rat decellularized testis scaffold with bone marrow-derived...
In vivo implant of the scaffolds with or without mesenchymal stem cells (MSCs) showed that appropriate positions for ... In this study, we aimed to evaluate the efficiency of the testis decellularized scaffold as a proper niche for stem cell ... and leydig-like cells. The scaffolds also provide a good niche for migrating DAZL-positive cells; however, they could not ... In vivo and in vitro studies point out that decellularized scaffold was non-toxic and performed a good platform for cell ...https://stemcellres.biomedcentral.com/articles/10.1186/s13287-018-1062-3
Characterization of bone marrow derived mesenchymal stem cells in suspension | Stem Cell Research & Therapy | Full Text
Functional similarities among genes regulated by OCT4 in human mesenchymal and embryonic stem cells. Stem Cells. 2007, 25: 3143 ... Isolation of mouse bone marrow mesenchymal stem cells (BMMSCs). The single suspension of bone marrow derived all nucleated ... Nitric OxideBone Marrow Mesenchymal Stem CellActivate Leukocyte Cell Adhesion MoleculeExtracellular Cell MatrixPeripheral Blood ... Bone marrow mesenchymal stem cells (BMMSCs) are hierarchical postnatal stem/progenitor cells capable of self-renewing and ...https://stemcellres.biomedcentral.com/articles/10.1186/scrt131
Influence of intrathecal delivery of bone marrow-derived mesenchymal stem cells on spinal inflammation and pain...
Prockop DJ, Gregory CA, Spees JL: One strategy for cell and gene therapy: harnessing the power of adult stem cells to repair ... Bone marrow-derived mesenchymal stromal cells for the repair of central nervous system injury. Bone Marrow Transplant. 2007, 40 ... Generation of rat bone marrow-derived mesenchymal stem cells and collection of conditioned medium. All experiments were ... Convincing immunomodulatory features have been ascribed to mesenchymal stem (stromal) cells (MSCs) derived from the bone marrow ...https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-014-0157-8
How Stem Cell Therapy Can Help Repair and Regenerate Your Body
Stem cells' main purpose is to maintain, heal and regenerate tissue wherever they are in your body; it's a continuous process ... Bone marrow tends to be very high in white blood cells and low in the mesenchymal cells. Isolating stem cells from fat tissue ... facility located at the Tulane Center for Gene Therapy. There, her work revolved around using bone marrow mesenchymal stem ... Stem Cell, a company founded in 1999. The company began bringing stem cells for cardiac care to the public. Muscle-derived stem ...https://articles.mercola.com/sites/articles/archive/2017/06/04/amp/stem-cell-therapy-repair-regenerate-body.aspx
Pharmaceuticals | Free Full-Text | Stem Cell Therapy: A New Treatment for Burns? | HTML
... embryonic and adult stem cells) or artificially obtained (induced pluripotent stem cells or iPSCs) and their fates have become ... We are at the beginning of a new era in medicine, with multiple applications for stem cell therapy, not only as a monotherapy, ... Severe burns have several indications for stem cell therapy, including enhancement of wound healing, replacement of damaged ... aim of this review is to describe well established characteristics of stem cells and to delineate new advances in the stem cell ...http://www.mdpi.com/1424-8247/4/10/1355/htm
Changes in phenotype and differentiation potential of human mesenchymal stem cells aging in vitro | Stem Cell Research &...
Human bone marrow-derived MSCs were passaged in vitro and cultivated with either DMEM-based or αMEM-based expansion media. ... The gene expression profile and adipogenic and osteogenic differentiation capability of MSCs at early (passage 4) and late ( ... Cells were prepared for subculture every 10 days up to passage 8 and were analyzed for cell morphology, proliferative capacity ... While the DMEM-based expansion medium better facilitated MSC proliferation in the early passages, the cell population doubling ...https://stemcellres.biomedcentral.com/articles/10.1186/s13287-018-0876-3
Frontiers | Advancements in stem cells treatment of skeletal muscle wasting | Physiology
... into account the advances in the isolation of new subpopulation of stem cells and in the creation of artificial stem cell ... into account the advances in the isolation of new subpopulation of stem cells and in the creation of artificial stem cell ... Muscle regeneration was attempted by means transplantation of myogenic cells (from myoblast to embryonic stem cells) and also ... from myoblast to embryonic stem cells) and also by interfering with the malignant processes that originate in pathological ...https://www.frontiersin.org/articles/10.3389/fphys.2014.00048/full
Stem cell therapy for degenerative intervertebral disk disease: Q and A with Wenchun Qu, M.D., M.S., Ph.D. - Mayo Clinic
... answers several key questions about the use of mesenchymal stem cell transplantation in treating this challenging condition. ... Appropriate bone marrow aspiration technique also determines the number of stem cells procured. I have developed a ... Gene. 2015;564:1.. Hunt CL, et al. Current understanding of safety and efficacy of stem cell therapy for discogenic pain - A ... III trial of intradiscal allogeneic bone marrow-derived MSC transplantation and a phase I trial of autologous adipose-derived ...https://www.mayoclinic.org/medical-professionals/physical-medicine-rehabilitation/news/stem-cell-therapy-for-degenerative-intervertebral-disk-disease/mqc-20437990
Adipose-derived regenerative cells exert beneficial effects on systemic responses following myocardial ischemia/reperfusion. |...
... bone marrow, and liver. Clinical trials and experimental studies have demonstrated that therapy with adipose-derived ... Flow cytometry revealed that freshly isolated ADRCs expressed stem cell markers CD90 and Sca-1, and mesenchymal lineage marker ... changes in metabolism and gene expressions of remote organs such as the spleen, ... Adipose-derived regenerative cells exert beneficial effects on systemic responses following myocardial ischemia/reperfusion.. [ ...https://www.sigmaaldrich.com/catalog/papers/27586454
rheumatoid arthritis Archives - Stem Cell Institute
How therapy using umbilical cord tissue-derived mesenchymal stem cells (MSCs) differs from bone marrow transplants used in ... How do we select umbilical cords for use? Medistem has identified proteins and genes in the cells that allow us to screen ... cord injury stem cell institute stem cell research stem cells stem cells panama stem cell therapy stem cell treatment stem cell ... Bone Marrow, Bone Marrow Stem Cells, Clinical Trials, Cord Blood Stem Cells, Medistem Labs Panama, mesenchymal stem cells, ...https://www.cellmedicine.com/tag/rheumatoid-arthritis/
immune system Archives - Stem Cell Institute
How therapy using umbilical cord tissue-derived mesenchymal stem cells (MSCs) differs from bone marrow transplants used in ... How do we select umbilical cords for use? Medistem has identified proteins and genes in the cells that allow us to screen ... Bone Marrow, News, Stem Cell Lecture Videos, Stem Cell Research, Stem Cell Therapy, Stem Cells, Video - Stem Cell Therapy, ... cord injury stem cell institute stem cell research stem cells stem cells panama stem cell therapy stem cell treatment stem cell ...https://www.cellmedicine.com/tag/immune-system/
Expansion of Human Adult Stem Cells from Bone Marrow Stroma: Conditions that Maximize the Yields of Early Progenitors and...
... a cell surface marker of cellular aging for human bone marrow-derived mesenchymal stem cells, Stem Cell Research & Therapy, ... One strategy for cell and gene therapy is to use adult stem cells from bone marrow stroma [1-4], referred to as mesenchymal ... Myogenic cells derived from rat bone marrow mesenchymal stem cells exposed to 5-azacytidine. Muscle Nerve 1995; 18: 1417-1426. ... of the anti-inflammatory effects of induced pluripotent stem cell-derived and bone marrow-derived mesenchymal stromal cells in ...http://onlinelibrary.wiley.com/doi/10.1634/stemcells.20-6-530/full?globalMessage=0
Genetic engineering of human stem cells for enhanced angiogenesis using biodegradable polymeric nanoparticles | PNAS
Bone marrow-derived human mesenchymal stem cells (hMSCs) and human embryonic stem cell-derived cells (hESdCs) were modified ... the efficacy of using stem cells alone to promote angiogenesis remains limited (19). Combined stem cells and gene therapy may ... Nucleofection is an efficient nonviral transfection technique for human bone marrow-derived mesenchymal stem cells. Stem Cells ... and human embryonic stem cell-derived cells (hESdCs). Treated stem cells demonstrated markedly enhanced hVEGF production, cell ...http://www.pnas.org/content/107/8/3317
Potential heart benefit found in stem cells ( Stem cell transplantation is among one ...)
We hope that the exploration of stem cells derived from new sources m... Human Menstrual Blood Derived Stem Cell Has a High ... Some previous research on the efficacy of stem cell therapy for heart ...,Potential,heart,benefit,found,in,stem,cells, ... Stem cell transplantation is among one of the most exciting and hotly ... ... Yet another potential new source for stem cells to be used for cardiac therapy is the bone marrow. To improve global left ...http://www.bio-medicine.org/biology-news/Potential-heart-benefit-found-in-stem-cells-2635-1/
Into the Eyes of Bone Marrow-Derived Mesenchymal Stem Cells Therapy for Myocardial Infarction and Other Diseases | Open Access...
Applications of bone marrow-derived mesenchymal stem cells (BM-MSCs) have been documented for diseases occur in the sports ... BM-MSCs have important clinical application value in cell replacement therapy, gene therapy and tissue regeneration. Bone ... Bone marrow mesenchymal stem cells (BM-MSCs) are mesoderm derived stem cells, which mainly exist in the interstitial connective ... Into the Eyes of Bone Marrow-Derived Mesenchymal Stem Cells Therapy for Myocardial Infarction and Other Diseases. J Cell Sci ...https://www.omicsonline.org/open-access/into-the-eyes-of-bone-marrowderived-mesenchymal-stem-cells-therapyfor-myocardial-infarction-and-other-diseases-2157-7013-1000266.php?aid=88300
Ovarian Cancer Stem Cells: A New Target for Cancer Therapy
Bone-marrow-derived mesenchymal stem cells (MSCs) are known to form fibroblast and myofibroblast populations in the tumor- ... V. Vathipadiekal, D. Saxena, S. C. Mok et al., "Identification of a potential ovarian cancer stem cell gene expression profile ... H. J. Li, F. Reinhardt, H. R. Herschman et al., "Cancer-stimulated mesenchymal stem cells create a carcinoma stem cell niche ... In 1997, Bonnet and Dick first isolated the cancer stem cells in leukemic cells expressing stem cell marker CD34 . Later, ...https://www.hindawi.com/journals/bmri/2013/916819/
The development of fibroblast colonies in monolayer cultures of guinea-pig bone marrow and spleen cells. - Semantic Scholar
The development of fibroblast colonies in monolayer cultures of guinea-pig bone marrow and spleen cells.' by A. J. Friedenstein ... The Hepatotoxic Effect Induced by Methotrexate Therapy and Protective Role of Bone Marrow-Derived Mesenchymal Stem Cells in ... Mini Review: Application of Human Mesenchymal Stem Cells in Gene and Stem Cells Therapy Era. *Ruixia Deng, Anna H Y Law, ... Enrichment for STRO-1 expression enhances the cardiovascular paracrine activity of human bone marrow-derived mesenchymal cell ...https://www.semanticscholar.org/paper/The-development-of-fibroblast-colonies-in-monolayer-Friedenstein-Chailakhjan/1ebb2db6e039aa3b52016f1ac868e117a20617db
Fibrinogen Concentration Influence on VEGF-Induced Differentiation of Adipose Tissue-Derived Stem Cells into Endothelial Cells
ECs-specific gene expression, and F-actin assembly. During the first 12 h after seeding, cells spread randomly, moved and ... However, the optimal substrates that promote differentiation of adipose tissue-derived stem cells (ASCs) into ECs remain to be ... Adipose tissue represents an abundant, practical source of donor tissue for stem cells which may be a useful source for ... Before inducing into ECs, ASCs did not express any markers of hematopoietic cells (CD34, CD45), ECs (CD31, CD34), and ...https://www.scientific.net/KEM.342-343.17
Application potential of mesenchymal stem cells from euthanased dogs: evaluation of the pathogen transmission risk | Veterinary...
Currently, bone marrow-derived MSCs (BMSCs) and adipose tissue-derived MSCs are the most prevalent MSCs in clinical trials ( ... For some injuries, stem cell therapy is reported to be more effective when applied in a timely manner (Park and others 2011). ... differentiation potential and gene expression profile. Consequently, their utility and effectiveness for medical applications ... Application potential of mesenchymal stem cells from euthanased dogs: evaluation of the pathogen transmission risk ...http://veterinaryrecord.bmj.com/content/178/14/342.2
Zinc Promotes Adipose-Derived Mesenchymal Stem Cell Proliferation and Differentiation towards a Neuronal Fate
... and clinical studies in all areas of stem cell biology and applications. The journal will consider basic, translational, and ... Stem Cells International is a peer-reviewed, Open Access journal that publishes original research articles, review articles, ... but also in other types of stem cells such as bone marrow mesenchymal stem cells [38, 39]. Thus, we hypothesized that zinc's ... adipose tissue is abundant and easily obtained and can serve as an ideal candidate for cell replacement therapy . Many ...https://www.hindawi.com/journals/sci/2018/5736535/
Cell Press Reviews: Stem Cells to Model and Treat Disease - 1st Edition
Stem Cells to Model and Treat Disease - 1st Edition. Print Book & E-Book. ISBN 9780124201910, 9780127999166 ... Current Therapies for Stroke. Bone Marrow-Derived Mesenchymal Stem Cells (MSCs). MSC Transplantation in Experimental Stroke ... Human PSCs for Gene Therapy Validations. Exploring Molecular Mechanisms of HD Using Human PSC Lines ... Cell Press Reviews: Stem Cells to Model and Treat Disease informs, inspires, and connects stem cell researchers and clinicians ...https://www.elsevier.com/books/cell-press-reviews-stem-cells-to-model-and-treat-disease/unknown/978-0-12-420191-0?utm_source=publicity&utm_medium=ElsConn&utm_campaign=CellPrRev
Molecular profile and cellular characterization of human bone marrow mesenchymal stem cells: donor influence on chondrogenesis....
We analyzed the phenotypic profiles, the expression of the stem cell marker genes Nanog, Oct3/4, and Sox2 and the multi-lineage ... Bone marrow mesenchymal stem cells (BM-MSCs) are well-characterized multipotent cells that can differentiate into different ... These two groups had different chondrogenic capacities and different expression levels of the stem cell marker genes. ... We compared culture-expanded selected cells with non-selected cells. ...https://www.semanticscholar.org/paper/Molecular-profile-and-cellular-characterization-of-Cicione-D%C3%ADaz-Prado/7a263e8a5065fac851322bf789668d9f7f02ea69
IJMS | Free Full-Text | Wharton's Jelly-Derived Mesenchymal Stem Cells: Phenotypic Characterization and Optimizing Their ...
A unique cell population of WJ that has been suggested as displaying the stemness phenotype is the mesenchymal stromal cells ( ... immune properties appear to be more robustly expressed and functional which are more comparable with fetal than adult-derived ... is a gelatinous tissue within the umbilical cord that contains myofibroblast-like stromal cells. ... Human bone marrow-derived mesenchymal stem cells in the treatment of gliomas. Cancer Res 2005, 65, 3307-3318. [Google Scholar] ...http://mdpi.com/1422-0067/14/6/11692/htm
Study of Bone Marrow Derived Stem Cells and Gene Therapy for Engineering of Cardiovascular Grafts
Bone marrow mesenchymal stem cells (MSCs) were cultured with alpha minimum essential medium ( -MEM). After two weeks, EPCs were ... Retroviral particles were produced using packaging cell line 293T cells. Gene transfer was carried out by exposing cells to ... In this study, rat EPCs were cultured from bone marrow, and plated in fibronectin-coated plates with EBM-2 medium. ... and gene therapy technologies are effective strategies in the inhibition of stenosis and thrombus formation and improving the ...https://www.scientific.net/KEM.288-289.31
How Stem Cell Therapy Can Help Repair and Regenerate Your Body : Conscious Life News
Stem cell therapy can treat tissue injuries, herniated discs, diabetes, organ damage, autoimmune diseases, neurological ... Bone marrow tends to be very high in white blood cells and low in the mesenchymal cells. Isolating stem cells from fat tissue ... facility located at the Tulane Center for Gene Therapy. There, her work revolved around using bone marrow mesenchymal stem ... Stem Cell, a company founded in 1999. The company began bringing stem cells for cardiac care to the public. Muscle-derived stem ...https://consciouslifenews.com/stem-cell-therapy-can-help-repair-regenerate-body/11138381/