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*  US Patent # 9,458,465. Compositions and methods to modulate cell membrane resealing - Patents.com
Disclosed herein are compositions and methods for repairing cell membranes. In addition, the invention relates to therapeutic ... dental cells, gastric cells, immune cells, skeletal muscle, and cardiac muscle cells. The ability to facilitate cell membrane ... Immuno-proteomic approach to excitation-contraction coupling in skeletal and cardiac muscle: molecular insights revealed by the ... kidney cell, neuronal cell, keratinocyte, dental cell, gastric cells, immune cells, skeletal muscle, cardiac muscle cell or ...
  http://patents.com/us-9458465.html
*  FXYD1 - Phospholemman precursor - Homo sapiens (Human) - FXYD1 gene & protein
... into the cell. Inhibits NKA activity in its unphosphorylated state and stimulates activity when phosphorylated. Reduces ... regulation of cardiac muscle cell membrane potential Source: BHF-UCL. *regulation of heart contraction Source: BHF-UCL ,p> ... p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of ... Cell membrane, Membrane. ,p>This section provides information on the disease(s) and phenotype(s) associated with a protein.,p>, ...
  http://www.uniprot.org/uniprot/O00168
*  Sodium
... helping carry nutrients to your cells, helping nerve cells in your brain and body to transfer information, enabling various ... Sodium chloride play a key role in allowing fluids to pass in and out of your cells, ... Tight control of cell membrane potential is critical for nerve impulse transmission, muscle contraction, and cardiac function. ... A cell's membrane potential is maintained by ion pumps in the cell membrane, especially the sodium, potassium-ATPase pumps. ...
  http://www.essense-of-life.com/healthtopics/A-225/sodium.html
*  The Effect of Acetylcholine on Muscle | LIVESTRONG.COM
... released by nerve cells in many parts of the peripheral nervous system. It controls the... ... the depolarization leads to muscle contraction.. Acetylcholine's Effect On Cardiac Muscle. Like smooth muscle, cardiac muscle ... A motor neuron contacts a muscle cell at a structure called a motor end plate. The muscle cell membrane contains nicotinic ... Acetylcholine's Effect On The Muscle Membrane. The influx of sodium depolarizes the muscle cell in the vicinity of the motor ...
  https://www.livestrong.com/article/373400-the-effect-of-acetylcholine-on-muscle/
*  Celivarone - Wikipedia
... causes depolarizations of cell membranes in node cells, which are then transmitted to cardiac muscle cells to induce ... Chapman, RA (January 1980). "Excitation-contraction Coupling in Cardiac Muscle". Progress in Biophysics and Molecular Biology. ... Mutations resulting in loss of function of K+ channels can result in delayed repolarization of the cardiac muscle cells. ... Disruptions in ion flow affect the heart's ability to contract by altering the resting membrane potential, affecting the cell's ...
  https://en.wikipedia.org/wiki/Celivarone
*  Scn5a - Sodium channel protein type 5 subunit alpha - Rattus norvegicus (Rat) - Scn5a gene & protein
Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium- ... This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. ... bundle of His cell action potential Source: BHF-UCL. *cardiac muscle cell action potential involved in contraction Source: BHF- ... p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of ...
  https://www.uniprot.org/uniprot/P15389
*  Cardiac muscle - Wikipedia
... and in both cases a contraction begins with a characteristic flow of ions across the cell membrane known as an action potential ... cardiac muscle cells are roughly rectangular, measuring 100-150μm by 30-40μm. Individual cardiac muscle cells are joined ... these substances give support and strength to the muscle cells, create elasticity in cardiac muscle, and keep the muscle cells ... Cardiac fibroblasts are vital supporting cells within cardiac muscle. They are unable to provide forceful contractions like ...
  https://en.wikipedia.org/wiki/Cardiac_muscle
*  Heart-warming | Article about heart-warming by The Free Dictionary
... that are formed in the cell membranes. These impulses develop rhythmically in the heart itself. The cardiac muscle's ability to ... The excitation of a myocardial cell membrane causes the contraction of the cell's myofibrils. The relationship between ... The four posterior small cells (cells 6-9) are interneurons, and the five anterior large cells (cells 1-5) are the motor ... atypical cells to generate impulses is related to the gradual reduction of the membrane potential in the cell membrane during ...
  http://encyclopedia2.thefreedictionary.com/heart-warming
*  CARDIAC ELECTROPHYSIOLOGY!!! Pharmaceutical Information by Gangadhar Hari
Heart has primarily two kinds of myocyte cells- Pacemaker cells (Those that can spontaneously initiate action potentials) and ... Majority if cardiac contraction is due to Nonpacemaker cells of the heart. CARDIAC ACTION POTENTIALS -As in other muscle cells ... This ions movement of is carried out with the help of various ion channels that are present in the cell membrane. -Unlike the ... The action potentials of various cardiac cells are as follows: -Each type of cardiac cell fires according to a specific cycle ...
  http://pharmainfo.net/gangadhar-hari/blog/cardiac-electrophysiology
*  Lecture 20 - Cardiac Muscle Contraction Bio416K Spring 2010 - -Na antiport Refractory Periods and Summation in Cardiac Muscle...
Na + antiport Refractory Periods and Summation in Cardiac Muscle Refractory Periods ... Cardiac Muscle Contraction Bio416K Spring 2010 from BIO Anatomy at University of Texas. - ... Slow speed of contraction  Autorhythmic cells with unstable membrane potentials  Cells connected by gap junctions - ... Action Potential of a Cardiac Muscle Contractile Cell ; Ca 2+ ATPase, Ca 2+ ...
  https://www.coursehero.com/file/5952709/Lecture-20-Cardiac-Muscle-Contraction-Bio416K-Spring-2010/
*  UniProt: G3VTH6 SARHA
DR GO; GO:0086002; P:cardiac muscle cell action potential involved in contraction; IEA:Ensembl. DR GO; GO:0007268; P:chemical ... DR GO; GO:0060371; P:regulation of atrial cardiac muscle cell membrane depolarization; IEA:Ensembl. DR GO; GO:0086091; P: ... in both central neurons and cardiac nodal cells and support CC calcium signaling in secretory cells and vascular smooth muscle ... including muscle CC contraction, hormone or neurotransmitter release, gene expression, CC cell motility, cell division and cell ...
  http://www.genome.jp/dbget-bin/www_bget?uniprot:G3VTH6_SARHA
*  UniProt: A0A0D9RKP5 CHLSB
DR GO; GO:0086002; P:cardiac muscle cell action potential involved in contraction; IEA:Ensembl. DR GO; GO:0051928; P:positive ... DR GO; GO:0060372; P:regulation of atrial cardiac muscle cell membrane repolarization; IEA:Ensembl. DR GO; GO:0086091; P: ... CC -!- FUNCTION: Voltage-sensitive calcium channels (VSCC) mediate the CC entry of calcium ions into excitable cells and are ... contraction, hormone or neurotransmitter release, gene expression, CC cell motility, cell division and cell death. The isoform ...
  http://www.genome.jp/dbget-bin/www_bget?uniprot:A0A0D9RKP5_CHLSB
*  Magnesium Supplement Uses, Benefits, Dosages, Side Effects & Interactions
It is necessary for muscle contraction, cardiac function, and neuronal impulse conduction inside the brain. ... According to the NMCD, "In cell membranes, a decreased concentration of magnesium and increased Ca to Mg ratio has also been ... possibly by enhancing glucose uptake into cells, increasing energy, improving cardiac performance, decreasing insulin ... muscle cramps, involuntary muscle contractions, seizures, and/or heart spasms. [1] ...
  https://nootriment.com/magnesium/
*  Freeze‐Fracture Immunocytochemistry: Fracture‐Label and Label‐Fracture for the Localization of Membrane Proteins - Current...
... of cell membranes at high resolution under the electron microscope ... fracture is a unique investigative tool for visualization of the en face topography of individual membrane leaflets ... contraction coupling in cardiac muscle. J. Mol. Cell. Cardiol. 32:1981‐1994. ... Samples (which can be of any isolated cells, cells in a monolayer, or isolated membrane fractions) ...
  http://www.currentprotocols.com/WileyCDA/CPUnit/refId-cb0428.html?quicktabs_cp=materials
*  Cardiac Glycosides and Cardiomyopathy | Hypertension
These drugs are positive inotropic agents and enhance cardiac contraction. The "cardiotonic steroids" cause cardiac muscle to ... lose K+ and gain Na+ because they inhibit the Na+ pump (Na+,K+-ATPase), a plasma membrane protein, present in all cells. The Na ... effects on the enzymatic function of the Na/K-ATPase to intracellular signaling functions triggering growth and cell ... How does inhibition of the Na+ pump augment cardiac contraction? The discovery of the Na+-Ca2+ exchanger and sarcoplasmic ...
  http://hyper.ahajournals.org/content/47/3/343
*  Is there life in the horny layer? Dihydropyridine and ryanodine receptors in the skin of female and male chickens (Gallus...
Molecular architecture of membranes involved in excitation-contraction coupling of cardiac muscle. J. Cell Biol. 129,659 -671. ... In avians, cardiac cells also seem to display the pattern of peripheral location of DHPR/RyR units. Excitation-contraction ... cardiac and smooth muscle cells (Franzini-Armstrong, 2004). Until the present study, DHPRs had not been shown to coexist with ... spark discharge region in isolated smooth muscle cells from guinea-pig mesenteric arteries. Cell Calcium 39,113 -129. ...
  http://jeb.biologists.org/content/211/9/1394
*  Frontiers | Mathematical models of cardiac pacemaking function | Physics
... initiating the contraction of cardiac muscle essential for pumping blood to the body. Despite the fundamental importance of ... Several mathematical models of sinoatrial node cell membrane electrophysiology have been constructed as based on different ... The sinoatrial node, a cluster of specialized pacemaking cells in the right atrium of the heart, spontaneously generates an ... initiating the contraction of cardiac muscle essential for pumping blood to the body. Despite the fundamental importance of ...
  https://www.frontiersin.org/articles/10.3389/fphy.2013.00020/full
*  Protocols and Video Articles Authored by Jianjie Ma (Translated to Hindi)
... the close contact between cell surface and intracellular membranes in muscle cells ensuring efficient excitation-contraction ... In cardiac muscle, spontaneous Ca2+ sparks underlie the rhythmic CICR activity during heart contraction. In skeletal muscle, ... membrane and plays a critical role in excitation-contraction coupling of skeletal and cardiac muscles. RyR normally exists in a ... MG53 Nucleates Assembly of Cell Membrane Repair Machinery Nature Cell Biology. Jan, 2009 , Pubmed ID: 19043407 Dynamic membrane ...
  https://www.jove.com/author/Jianjie_Ma?language=Hindi
*  Nerve and Muscle / Edition 4 by Richard D. Keynes, David J. Aidley, Christopher L.-H. Huang | | 9780521519557 | Hardcover |...
The chapters on muscle - skeletal, cardiac and smooth - show how the concepts elaborated for nerve cells are relevant to ... clarifying their mechanisms in terms of ion flow through molecular channels in cell membranes. There then follows an account of ... The mechanism of contraction in skeletal muscle; 10. The activation of skeletal muscle; 11. Contractile function in skeletal ... the activation of skeletal muscle and the function of cardiac and smooth muscle, reflecting exciting new developments in these ...
  https://www.barnesandnoble.com/w/nerve-and-muscle-richard-d-keynes/1100295875?ean=9780521519557&itm=12
*  Heart failure cells | Article about heart failure cells by The Free Dictionary
Find out information about heart failure cells. river, 180 mi long, rising in the low prairie country near the Little Missouri ... that are formed in the cell membranes. These impulses develop rhythmically in the heart itself. The cardiac muscle's ability to ... The excitation of a myocardial cell membrane causes the contraction of the cell's myofibrils. The relationship between ... The four posterior small cells (cells 6-9) are interneurons, and the five anterior large cells (cells 1-5) are the motor ...
  http://encyclopedia2.thefreedictionary.com/heart+failure+cells
*  T-tubule - Wikipedia
... are extensions of the cell membrane that penetrate into the centre of skeletal and cardiac muscle cells. With membranes that ... excitation-contraction coupling). When contraction of a muscle is needed, stimulation from a nerve or an adjacent muscle cell ... They are found in ventricular muscle cells in most species, and in atrial muscle cells from large mammals. In cardiac muscle ... In cells lacking T-tubules such as smooth muscle cells, diseased cardiomyocytes, or muscle cells in which T-tubules have been ...
  https://en.wikipedia.org/wiki/T-tubule
*  T wave - Wikipedia
... because it represents the period in which the cardiac muscle cells of the heart can relax and prepare for the next contraction ... Once the action potential is over, potassium ions flow out of the cell due to increased cell membrane permeability to those ... The refractory period of cardiac muscle is distinct from skeletal muscle. Nerves that innervate skeletal muscle have an ... In skeletal muscle cells, repolarization is simple. Sodium ions flowed into the cell earlier to depolarize it and cause ...
  https://en.wikipedia.org/wiki/T_wave
*  Ciclosporin - Wikipedia
The MPTP is found in the mitochondrial membrane of cardiac myocytes (heart muscle cells) and moves calcium ions (Ca2+ ) into ... In T-cells, activation of the T-cell receptor normally increases intracellular calcium, which acts via calmodulin to activate ... To allow for normal contraction, intracellular Ca2+ increases, and the MPTP in turn opens, shuttling Ca2+ into the mitochondria ... In short, it is nephrotoxic, neurotoxic, increases the risk of squamous cell carcinoma and infections, and often causes ...
  https://en.wikipedia.org/wiki/Ciclosporin
*  Calcium-induced calcium release - Wikipedia
Instead, CICR is thought to be crucial for excitation-contraction coupling in cardiac muscle and it is now obvious that CICR is ... When an action potential depolarizes the cell membrane, voltage-gated Ca2+ channels (e.g., L-type calcium channels) are ... in the insulin-secreting pancreatic beta cells and many other cells. Since CICR is a positive-feedback system, it has been of ... In cardiac muscle, the result of CICR is observed as a spatio-temporally restricted Ca2+ spark. The result of CICR across the ...
  https://en.wikipedia.org/wiki/Calcium-induced_calcium_release
*  T-type calcium channel - Wikipedia
Within cardiac and smooth muscle cells voltage-gated calcium channel activation initiates contraction directly by allowing the ... through the membrane when the channel is activated. When membrane depolarization occurs in a cell membrane where these channels ... Therefore, while they helped provide stronger and quicker depolarization of cardiac muscle cells and thalamus nerve cells, T- ... is important for the repetitive firing of action potentials in cells with rhythmic firing patterns such as cardiac muscle cells ...
  https://en.wikipedia.org/wiki/T-type_calcium_channel