Loading...


*  Molecular profile of CD34-lineage- cells differentiated | Open-i
... cells differentiated with IL-15 plus IL-21. Panel A: Molecular features of cytokine-differentiated CD34-lineage- cells. The e ... CD34-lineage- cells cultured with IL-15 and IL-21 harboured un-rearranged TCRγ genes, similar to freshly isolated CD34-lineage ... CD34-lineage- cells cultured with IL-15 and IL-21 harboured un-rearranged TCRγ genes, similar to freshly isolated CD34-lineage ... CD34-lineage- cells expanded by IL-21 in combination with IL-15 acquired lymphoid morphology and killer-cell immunoglobulin- ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2743656_1471-2172-10-46-4&req=4
*  Laurie A. Milner, M.D. - Wilmot Cancer Institute - University of Rochester Medical Center
As a model system, they are using embryonic stem (ES) cells to evaluate the role of Notch signaling in hematopoietic cell fate ... they hope to delineate the effects of Notch signaling on lineage specification and self-renewal of progenitors at various ... Chapter Title: Notch in hematopoiesis: Cell fate decisions and self-renewal of progenitors. Book Title: Cell Therapy. Author ... Mammalian hematopoiesis is a unique developmental process in which stem cells continue to generate vast numbers of diverse cell ...
  https://www.urmc.rochester.edu/cancer-institute/team/profile.aspx?urid=23387805
*  Who Needs Pluripotency? - Direct Lineage Conversion of Terminally Differentiated Hepatocytes to Functional Neurons | Stem Cells...
Atkinson Direct conversion of one somatic cell to another somatic cell type, completely bypassing the pluripotent stage through ... the forced expression of lineage specific transcription factors has emerged as a large ... From Cell Stem Cell. By Stuart P. Atkinson. Direct conversion of one somatic cell to another somatic cell type, completely ... The Stem Cells Portal is a shared platform for the STEM CELLS and STEM CELLS Translational Medicine sister journals, providing ...
  http://www.stemcellsportal.com/content/who-needs-pluripotency-direct-lineage-conversion-terminally-differentiated-hepatocytes
*  PA-07-127: Cell Lineage and Developmental Studies in Hearing and Balance (R01)
Cell Lineage and Developmental Studies in Hearing and Balance (R01) PA-07-127. NIDCD ... Title: Cell Lineage and Developmental Studies in Hearing and Balance (R01). Announcement Type This is a reissue of PA-04-118, ... Several accomplishments, such as the completion of detailed cell lineage and fate mapping analyses, the identification of key ... Advancement of fate mapping and lineage analysis done at single cell resolution using real-time assessment. ...
  https://grants.nih.gov/grants/guide/pa-files/PA-07-127.html
*  Molecular Systems Immunology - btk
Stem Cell Reports. 4:519-528.. Tripathi SK, Lahesmaa R. (2014) Transcriptional and epigenetic regulation of T-helper lineage ... Cell Stem Cell, 8:200-213. Elo LL, Järvenpää H, Tuomela S, Raghav S, Ahlfors H, Laurila K, Gupta B, Lund RJ, Tahvanainen J, ... and related 5-methylcytocine hydroxylases modulate pluripotency and cell lineage specification in mouse embryonic stem cells. ... Identification of global regulators of T-helper cell lineage specification. Genome Med. 7:122. ...
  https://www.btk.fi/research/molecular-systems-immunology/
*  Simultaneous analysis of rag2 transcription and recombi | Open-i
Simultaneous analysis of rag2 transcription and recombinase activity in B lineage progenitors. (A) Bone marrow obtained from ... J recombination to initiate in early B lineage progenitors.We find that single B lineage precursors express an active V(D)J ... The percentage of cells in each region is given. (B) VEX and GFP expression was similarly examined in Ly6C−DX5− fraction A2( ... J recombination to initiate in early B lineage progenitors. We find that single B lineage precursors express an active V(D)J ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2211822_20031802f2&req=4
*  Immunology | The EMBO Journal
However, the characteristics of the stage just before a cell becomes restricted to the B‐cell lineage are less understood. ... B‐cell differentiation is one of the most recognized examples of the progressive lineage commitment that is distinctive for ... Single‐cell RNA‐seq reveals that EPLM is a heterogeneous population composed of a mixture of cells with distinct genetic ... Regulatory T cells constrain the TCR repertoire of antigen‐stimulated conventional CD4 T cells ...
  http://d2ni3bh4dzb2ig.cloudfront.net/collection/immunology
*  The Allen Discovery Center for Cell Lineage Tracing | www.admissions.caltech.edu
Here, MEMOIR cells were variably activated, as seen by the bright cyan nuclear fluorescence in some cells. The cells recorded ... "A critical step to solving this problem is to be able to track the progeny of cells-that is, their lineage. The funding from ... "The goal is for each cell to be able to tell us its own individual history, including its lineage and the specific molecular ... and work together to map lineage and developmental histories of cells.". "One of the fundamental questions in biology is to ...
  http://www.admissions.caltech.edu/node/1722
*  In vivo genetic cell lineage tracing reveals that oviductal secretory cells self-renew and give rise to ciliated cells |...
In vivo genetic cell lineage tracing reveals that oviductal secretory cells self-renew and give rise to ciliated cells ... In vivo genetic cell lineage tracing reveals that oviductal secretory cells self-renew and give rise to ciliated cells ... In vivo genetic cell lineage tracing reveals that oviductal secretory cells self-renew and give rise to ciliated cells ... In vivo genetic cell lineage tracing reveals that oviductal secretory cells self-renew and give rise to ciliated cells ...
  http://dev.biologists.org/content/early/2017/07/21/dev.149989.article-info
*  EMBO practical course
Embryonic stem cells and chimera production * Production of genetic mosaics by cell transplantation, cell lineage tracing * ... and positional cloning strategies Mesoderm development Development of the nervous system Dorso-ventral pattern formation Cell ...
  http://www.bio.net/bionet/mm/zbrafish/1997-November/003781.html
*  CELL LINEAGE | Shapiro
Lineage analysis of intestinal epithelial cells. We have developed a method for single cell extraction of epithelial cells from ... In particular, the reconstruction of a cell lineage tree, capturing the cell division history of organism cells, can be ... The reconstructed cell lineage trees of acute myeloid leukemia (AML) patients demonstrated that leukemia cells at relapse were ... Quantifying the ability to reconstruct a cell-lineage tree using somatic mutations. The development of cells within a multi- ...
  http://www.weizmann.ac.il/math/Shapiro/cell-lineage
*  Cell Lineage - QIAGEN
Cell Lineage Identification RT2 Profiler PCR Array The Human Cell Lineage Identification RT² Profiler PCR Array profiles the ... Cell Lineage Identification RT2 Profiler PCR Array The Mouse Cell Lineage Identification RT² Profiler PCR Array profiles the ... Cell Lineage Identification RT2 Profiler PCR Array The Rat Cell Lineage Identification RT² Profiler PCR Array profiles the ... Cell Lineage Identification EpiTect ChIP qPCR Array The Human Cell Lineage EpiTect Chip qPCR Array profiles the histone ...
  https://www.qiagen.com/us/shop/genes-and-pathways/complete-biology-list/cell-lineage/
*  Cell lineage - Wikipedia
Cell lineage denotes the developmental history of a tissue or organ from the fertilized embryo. Cell lineage can be studied by ... These more variable cell fates are thought to be due to the cells' interaction with the environment. Cell lineage can be ... This causes the cell lineage and cell fate to be highly correlated. Other organisms, such as humans, have variable lineages and ... is activated and permanently labels the cell of interest and its offspring cells, thus the name cell lineage tracing. With the ...
  https://en.wikipedia.org/wiki/Cell_lineage
*  'cell lineage' Protocols and Video...
... cell lineage' include 'Co-localization of Cell Lineage Markers and the Tomato Signal', 'Cell Lineage Analyses and Gene Function ... Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets', 'Ablation of a Single Cell From Eight-cell ... Live Imaging Followed by Single Cell Tracking to Monitor Cell Biology and the Lineage Progression of Multiple Neural ... Cell Sorting of Neural Stem and Progenitor Cells from the Adult Mouse Subventricular Zone and Live-imaging of their Cell Cycle ...
  https://www.jove.com/keyword/cell+lineage
*  Stem cell lineage database - Wikipedia
The Stem Cell Lineage Database (SCLD) is a database of resources used to identify cell lineages. The Stem Cell Lineage Database ... "about cell type gene expression, cell lineage maps and stem cell differentiation protocols for both human and mouse stem cells ... A stem cell lineage database for the annotation of cell types and developmental lineages". Nucleic Acids Research. 39 (Database ... The Stem Cell Lineage Database could help compare stem cell information around the world and eliminate taking a global gene ...
  https://en.wikipedia.org/wiki/Stem_cell_lineage_database
*  KEGG PATHWAY: Hematopoietic cell lineage - Reference pathway
A CLP gives rise to the lymphoid lineage of white blood cells or leukocytes-the natural killer (NK) cells and the T and B ... Hematopoietic cell lineage - Reference pathway [ Pathway menu , Organism menu , Pathway entry , Show description , User data ... Cells undergoing these differentiation process express a stage- and lineage-specific set of surface markers. Therefore cellular ... A CMP gives rise to the myeloid lineage, which comprises the rest of the leukocytes, the erythrocytes (red blood cells), and ...
  http://www.genome.jp/kegg-bin/show_pathway?map04640
*  Transcription Factors and Helper T Cell Lineage Determination | Science
Transcription Factors and Helper T Cell Lineage Determination Message Subject. (Your Name) has forwarded a page to you from ...
  http://science.sciencemag.org/content/307/5708/313.12
*  KEGG PATHWAY: Hematopoietic cell lineage - Homo sapiens (human)
Hematopoietic cell lineage - Homo sapiens (human) [ Pathway menu , Organism menu , Pathway entry , Download KGML , Show ... A CLP gives rise to the lymphoid lineage of white blood cells or leukocytes-the natural killer (NK) cells and the T and B ... Cells undergoing these differentiation process express a stage- and lineage-specific set of surface markers. Therefore cellular ... A CMP gives rise to the myeloid lineage, which comprises the rest of the leukocytes, the erythrocytes (red blood cells), and ...
  http://www.genome.jp/kegg-bin/show_pathway?hsa04640+3674
*  Control of Cell Survival and Proliferation in the Oligodendrocyte Cell Lineage
... Martin Raff, Yasu Tokumoto, and Dean Tang ... MRC Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, UK. ...
  https://www.hindawi.com/journals/tswj/2001/595026/abs/
*  T Cell Lineage Commitment: Identity and Renunciation | The Journal of Immunology
Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic ... Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3. Nat. Immunol. 8: 845- ... The B-lineage exclusion mechanism must inactivate some crucial B cell function that T and B cells do not share. The B cell- ... early T cells); DN2a, c-Kit++ CD44+ CD25+ DN cells; DN2b, c-Kit+ CD44+ CD25+ DN cells; DN3a, c-Kitlow CD44low CD25+ DN cells; ...
  http://www.jimmunol.org/content/186/12/6649
*  Cell Lineage Allocation Within the Inner Cell Mass of the Mouse Blastocyst | SpringerLink
... the early mouse embryo consists of three distinct cell lineages: the epiblast (EPI), primitive endoderm (PrE), and ... Inner Cell Mass Asymmetric Division Cell Fate Decision Lineage Bias Inner Cell Mass Cell These keywords were added by machine ... Johnson MH, Ziomek CA (1981) The foundation of two distinct cell lineages within the mouse morula. Cell 24:71-80PubMedCrossRef ... 2012) Cell Lineage Allocation Within the Inner Cell Mass of the Mouse Blastocyst. In: Kubiak J. (eds) Mouse Development. ...
  https://link.springer.com/chapter/10.1007/978-3-642-30406-4_10
*  Experts and Doctors on cell lineage in Ōsaka, Japan
Scientific Experts about Experts and Doctors on cell lineage in Ōsaka, Japan ... type IV cells differentiate into dark and light cells and type III cells differentiate to type II cells within the light cell ... type IV cells differentiate into dark and light cells and type III cells differentiate to type II cells within the light cell ... Most PAL cells were derived from crippled post-GC cells, which usually could not survive. Transformation of such B cells ...
  http://www.labome.org/locale/japan/experts-and-doctors-on-cell-lineage-in---saka--japan-836924.html
*  Features of cell lineage in preimplantation mouse development | Development
The cell lineage of the mouse was studied from the 2-cell stage to the blastocyst. Lineage to the 8-cell stage was followed ... Lineage to the blastocyst was followed by injecting oil drops into cells at the 8-cell stage, and then following the ... Between the 8-cell stage and the blastocyst, the deep cells contributed more frequently to the inner cell mass than did the ... Each cell from the 2-cell stage divided to form two daughter cells which remained attached. Subsequently, these two daughters ...
  http://dev.biologists.org/content/48/1/53
*  Altered subcellular localization of transcription factor TEAD4 regulates first mammalian cell lineage commitment | PNAS
Early cell lineage specification in a marsupial: a case for diverse mechanisms among mammals ... Altered subcellular localization of transcription factor TEAD4 regulates first mammalian cell lineage commitment. Pratik Home, ... Thus, differential function of TEAD4 rather than expression itself regulates specification of the first two cell lineages. We ... Altered subcellular localization of transcription factor TEAD4 regulates first mammalian cell lineage commitment ...
  http://www.pnas.org/content/early/2012/04/19/1201595109
*  Vascular endothelial cell lineage-specific promoter in transgenic mice | Development
We report the first vascular endothelial cell lineage-specific (including angioblastic precursor cells) 1.2 kb promoter in ... Vascular endothelial cell lineage-specific promoter in transgenic mice. T.M. Schlaeger, Y. Qin, Y. Fujiwara, J. Magram, T.N. ... Vascular endothelial cell lineage-specific promoter in transgenic mice. T.M. Schlaeger, Y. Qin, Y. Fujiwara, J. Magram, T.N. ... Vascular endothelial cell lineage-specific promoter in transgenic mice. T.M. Schlaeger, Y. Qin, Y. Fujiwara, J. Magram, T.N. ...
  http://dev.biologists.org/content/121/4/1089?ijkey=d5db8d3b1b1feb5ece9843bb346336f94d1e40e5&keytype2=tf_ipsecsha