*  p53 Signaling - QIAGEN
... the genes ATM and ATR are activated and phosphorylate the cell cycle checkpoint proteins CHEK1 and CHEK2. During this process, ... the genes ATM and ATR are activated and phosphorylate the cell cycle checkpoint proteins CHEK1 and CHEK2. During this process, ... Genes targeted by p53 initiate multiple processes such as cell cycle arrest and apoptosis. A wide variety of cancers carry p53 ... Genes targeted by p53 initiate multiple processes such as cell cycle arrest and apoptosis. A wide variety of cancers carry p53 ...
  https://www.qiagen.com/fi/shop/genes-and-pathways/complete-biology-list/p53-signaling/
*  'Addiction' to Cell-cycle Proteins Shuts Down Tumors in Mice:...
... scientists have safely shut down breast cancer and a form of leukemia in mice by targeting abnormal proteins to which the ... that control cells' growth cycle. Many types of cancer have abnormal amounts of the proteins, spurring the cells to grow too ... Addiction' to Cell-cycle Proteins Shuts Down Tumors in Mice: Study. by Rukmani Krishna on October 22, 2012 at 11:31 PM Cancer ... Cyclin proteins act as "checkpoint" guards to control cell's cycle of rest, growth and division. The D-cyclins determine when a ...
  http://www.medindia.net/news/addiction-to-cell-cycle-proteins-shuts-down-tumors-in-mice-study-108903-1.htm
*  "Novel Cell Cycle Proteins In Apicomplexan Parasites" by Carrie Butler
We named the protein inner membrane complex protein 16 (IMC16) due to its IMC localization however; this protein uniquely ... and sorted the resulting set of dual cell cycle regulated orthologs (744 total) into protein pairs conserved across many ... we devised a strategy to identify the core set of apicomplexan cell division cycling genes with important roles in parasite ... Hypothetical proteins comprise roughly half of the predicted gene complement of T. gondii and P. falciparum and represent the ...
  http://scholarcommons.usf.edu/etd/5195/
*  Cell Cycle Protein Expression in Vascular Smooth Muscle Cells In Vitro and In Vivo Is Regulated Through Phosphatidylinositol 3...
... and Rapamycin-Sensitive Induction of Cell Cycle Protein Expression. We postulated that an altered pattern of cell cycle protein ... For example, protein kinase B (Akt) may play a significant role. However, the inhibition of cell cycle protein upregulation ... Cell Cycle Protein Expression in Vascular Smooth Muscle Cells In Vitro and In Vivo Is Regulated Through Phosphatidylinositol 3- ... Cell Cycle Protein Expression in Vascular Smooth Muscle Cells In Vitro and In Vivo Is Regulated Through Phosphatidylinositol 3- ...
  http://atvb.ahajournals.org/content/21/7/1152
*  CDC20B - Cell division cycle protein 20 homolog B - Homo sapiens (Human) - CDC20B gene & protein
Cell division cycle protein 20 homolog BAdd BLAST. 519. Proteomic databases. PaxDb, a database of protein abundance averages ... Cluster: Cell division cycle protein 20 homolog B. 31. Q86Y33-3. F7GV04. UPI000036D148. UPI0002746305. UPI00027F8351. ... Cluster: Cell division cycle protein 20 homolog B. 125. Q86Y33-3. F7GV04. UPI00027F8351. UPI000036D148. UPI0005F3B731. ... sp,Q86Y33,CD20B_HUMAN Cell division cycle protein 20 homolog B OS=Homo sapiens GN=CDC20B PE=1 SV=3 ...
  http://www.uniprot.org/uniprot/Q86Y33
*  Distinct structural forms of type I collagen modulate cell cycle regulatory proteins in mesangial cells.
Extracellular matrix molecules profoundly regulate cell behavior, including proliferation. In glomerulonephritis, type I ... Blood Proteins / pharmacology. Cell Adhesion / physiology. Cell Cycle Proteins*. Cell Nucleus / enzymology. Cells, Cultured. ... 0/Blood Proteins; 0/Cdkn1b protein, rat; 0/Cell Cycle Proteins; 0/Cyclin E; 0/Integrin alpha1beta1; 0/Integrins; 0/Microtubule- ... Mitogen-Activated Protein Kinase 1 / metabolism. Mitogen-Activated Protein Kinase 3. Mitogen-Activated Protein Kinases / ...
  http://www.biomedsearch.com/nih/Distinct-structural-forms-type-collagen/10972675.html
*  cell cycle checkpoint control protein RAD9A isoform 1 [Homo sapiens] - Protein - NCBI
cell cycle checkpoint control protein RAD9A isoform 1 [Homo sapiens] cell cycle checkpoint control protein RAD9A isoform 1 [ ... This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle ... Protein expression data [Model Organism Protein Expres...] Protein expression data. Model Organism Protein Expression Database ... cell cycle checkpoint control protein RAD9A isoform 1 [Homo sapiens]. NCBI Reference Sequence: NP_004575.1 ...
  https://www.ncbi.nlm.nih.gov/protein/4759022
*  TACC - Cell Cycle - Regulator Proteins - Proteins - Products
Transforming acidic coiled-coil (TACC), an evolutionally conserved protein family, has been shown to be involved in the process ... A small compound targeting TACC3 revealed its different spatiotemporal contributions for spindle assembly in cancer cells. ...
  https://www.axonmedchem.com/products/proteins/regulator-proteins/cell-cycle/tacc
*  Modulation of cell cycle regulatory protein expression and suppression of tumor growth by mimosine in nude mice.
... *Authors: *H ... Chang, H., Weng, C., Yen, M., Chuang, L., Hung, W.'Modulation of cell cycle regulatory protein expression and suppression of ... Chang, H., Weng, C., Yen, M., Chuang, L., Hung, W.'Modulation of cell cycle regulatory protein expression and suppression of ... However, whether mimosine may modulate the expression of these cell cycle regulatory proteins and suppress tumor growth in vivo ...
  https://www.spandidos-publications.com/ijo/17/4/659
*  Cell division cycle protein 73 homolog | definition of Cell division cycle protein 73 homolog by Medical dictionary
What is Cell division cycle protein 73 homolog? Meaning of Cell division cycle protein 73 homolog medical term. What does Cell ... Looking for online definition of Cell division cycle protein 73 homolog in the Medical Dictionary? Cell division cycle protein ... Cell division cycle protein 73 homolog , definition of Cell division cycle protein 73 homolog by Medical dictionary https:// ... redirected from Cell division cycle protein 73 homolog) CDC73. A gene on chromosome 1q25 that encodes a tumour suppressor ...
  https://medical-dictionary.thefreedictionary.com/Cell+division+cycle+protein+73+homolog
*  Expression of Cell-Cycle-regulated Proteins pRb2/p130, p107, p27kip1, p53, mdm-2, and Ki-67 (MIB-1) in Prostatic Gland...
... et al Expression of cell-cycle-associated proteins pRB2/p130 and p27/Kip1 in vulvar squamous cell carcinomas. Hum. Pathol., 32: ... which is involved in cell cycle control and cell differentiation. The RB protein is mutated or absent in a variety of human ... Expression of Cell-Cycle-regulated Proteins pRb2/p130, p107, p27kip1, p53, mdm-2, and Ki-67 (MIB-1) in Prostatic Gland ... Expression of Cell-Cycle-regulated Proteins pRb2/p130, p107, p27kip1, p53, mdm-2, and Ki-67 (MIB-1) in Prostatic Gland ...
  http://clincancerres.aacrjournals.org/content/8/6/1808
*  "Targeting Cell Cycle Proteins in Breast Cancer Cells with siRNA by Usi" by Manoj Parmar, Hamidreza Montazeri Aliabadi et al.
Using a library of siRNAs against cell cycle proteins, we identified cell division cycle protein 20 (CDC20), a recombinase ... MDA-MB-231 and MCF7 cells with respect to another well-studied cell cycle protein, kinesin spindle protein. We also explored ... There was no apparent effect of silencing selected cell cycle proteins on the potency of the chemotherapy drug doxorubicin. The ... The presented study highlighted specific cell cycle protein targets critical for breast cancer therapy, and provided a ...
  http://digitalcommons.chapman.edu/pharmacy_articles/142/
*  Cell division cycle 7-related protein kinase - Wikipedia
The protein is expressed at constant levels throughout the cell cycle. The gene coding for the Dbf4 or ASK protein is regulated ... Although expression levels of the protein appear to be constant throughout the cell cycle, the protein kinase activity appears ... Cell division cycle 7-related protein kinase is an enzyme that in humans is encoded by the CDC7 gene. The Cdc7 kinase is ... The product encoded by this gene is predominantly localized in the nucleus and is a cell division cycle protein with kinase ...
  https://en.wikipedia.org/wiki/Cell_division_cycle_7-related_protein_kinase
*  Cell cycle regulatory protein | definition of Cell cycle regulatory protein by Medical dictionary
Cell cycle regulatory protein explanation free. What is Cell cycle regulatory protein? Meaning of Cell cycle regulatory protein ... Looking for online definition of Cell cycle regulatory protein in the Medical Dictionary? ... The results suggest that maslinic acid induces G1 cell cycle arrest with induction of Gl phase cell cycle regulatory proteins ... Differential effects of cell cycle regulatory protein [p21.. 4A, wild type cells exhibited increased expression of the cell ...
  https://medical-dictionary.thefreedictionary.com/Cell+cycle+regulatory+protein
*  Cell cycle checkpoint protein RAD1
Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is ... This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated ... The DNA binding domain (DBD) within the hLigI catalytic fragment interacts with both PCNA and the heterotrimeric cell-cycle ... to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 ...
  https://pharos.nih.gov/idg/targets/O60671
*  Cell division cycle protein 16 homolog
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72 ... a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The ... regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 23 ... The APC complex is a cyclin degradation system that governs exit from mitosis by targeting cell cycle proteins for degredation ...
  https://pharos.nih.gov/idg/targets/Q13042
*  Cell division cycle protein 23 homolog
GO Process for Cell division cycle protein 23 homolog. protein ubiquitination involved in ubiquitin-dependent protein catabolic ... APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72 ... a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting ... a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The ...
  https://pharos.nih.gov/idg/targets/Q9UJX2
*  Cell-cycle-dependent association of protein phosphatase 1 and focal adhesion kinase | Biochemical Journal
Cell-cycle-dependent association of protein phosphatase 1 and focal adhesion kinase. Marco FRESU, Mariarita BIANCHI, J. Thomas ... Cell-cycle-dependent association of protein phosphatase 1 and focal adhesion kinase ... Cell-cycle-dependent association of protein phosphatase 1 and focal adhesion kinase ... Cell-cycle-dependent association of protein phosphatase 1 and focal adhesion kinase ...
  http://www.biochemj.org/content/358/2/407
*  Compensatory Stabilization of RIIβ Protein, Cell Cycle Deregulation, and Growth Arrest in Colon and Prostate Carcinoma Cells by...
B, cell cycle analysis. In an attempt to synchronize a homogeneous cell population at a particular cell cycle phase, untreated ... Cell Cycle Analysis of LS-174T Cells.. Fixed cells were treated with 1 mg/ml RNase (Sigma Chemical Co., St. Louis, MO) for 30 ... Compensatory Stabilization of RIIβ Protein, Cell Cycle Deregulation, and Growth Arrest in Colon and Prostate Carcinoma Cells by ... Compensatory Stabilization of RIIβ Protein, Cell Cycle Deregulation, and Growth Arrest in Colon and Prostate Carcinoma Cells by ...
  http://clincancerres.aacrjournals.org/content/6/9/3434
*  Effects of Ras Oncoprotein - Effects of Ras Oncoprotein and Growth Factors on the Cell Cycle Regulators Retinoblastoma Protein...
Effects of Ras Oncoprotein and Growth Factors on the Cell Cycle Regulators Retinoblastoma Protein Rb and ... Effects of Ras Oncoprotein and Growth Factors on the Cell Cycle Regulators Retinoblastoma Protein Rb and p21 Cip1/Waf1 Laura ... Effects of Ras Oncoprotein and Growth Factors on the Cell Cycle Regulators Retinoblastoma Protein Rb and p21 Cip1/Waf1 Laura ... 12 Cell cycle and G 1 restriction point control ___________________________________________12 Ras-proteins, important ...
  https://www.coursehero.com/file/5461906/Effects-of-Ras-Oncoprotein/
*  Replication Protein A Links Cell Cycle Progression and the Onset of Neurogenesis in Drosophila Optic Lobe Development | Journal...
To verify that the loss of these cell cycle regulators indeed affected cell cycle progression of NE cells, we used BrdU ... Here, we show that replication protein A (RPA), as well as the core cell cycle regulators, regulates the transition of NE cell ... The cell cycle control has been noted for its close correlation between cell cycle length and the modes of neural progenitor ... 9E,E'). These data point to a common mechanism underlying Notch inactivation by the cell cycle: the rate of cell cycle ...
  http://www.jneurosci.org/content/33/7/2873
*  Cell division cycle-associated protein 7
Data indicate that cell division cycle associated 7 protein (Cdca7) is strongly up-regulated in the hemogenic population during ... Toward a comprehensive characterization of a human cancer cell phosphoproteome.. 23166294. 2013. The MYC-associated protein ... The CDCA7 transcription factor regulates cell proliferation.. 23166294. CDCA7 associates with MYC and this association is ... Overexpression of this gene is found to enhance the transformation of lymphoblastoid cells, and it complements a transformation ...
  https://pharos.nih.gov/idg/targets/Q9BWT1
*  Cell division cycle-associated protein 2
This gene encodes a targeting subunit of the cell-cycle associated protein, protein phosphatase 1, with a role in targeting ... and might be associated with OSCC progression by preventing cell-cycle arrest and apoptosis.. ... These two proteins comprise a phosphatase complex that is involved in nuclear envelope reformation and regulation of the DNA ... The encoded protein may also play a role in cancer progression. Alternative splicing results in multiple transcript variants. [ ...
  https://pharos.nih.gov/idg/targets/Q69YH5
*  KDP-1 is a nuclear envelope KASH protein required for cell-cycle progression | Journal of Cell Science
We predict that KDP-1 functions to recruit components of the cell cycle to the NE or to sequester cell-cycle proteins at the NE ... How could a KASH protein presumably localized to the ONM regulate the cell cycle? Other KASH proteins function with SUN ... kdp-1 is required for normal cell-cycle progression in the early embryo. The cell cycle in the early blastomeres of C. elegans ... The data suggest that KDP-1 is a novel KASH protein that functions to ensure the timely progression of the cell cycle between ...
  http://jcs.biologists.org/content/122/16/2895
*  Saylor.org's Cell Biology/Trimeric G (Guanosine) Protein Cycle - Wikibooks, open books for an open world
Saylor.org's Cell Biology/Trimeric G (Guanosine) Protein Cycle. From Wikibooks, open books for an open world ... Retrieved from "https://en.wikibooks.org/w/index.php?title=Saylor.org%27s_Cell_Biology/Trimeric_G_(Guanosine)_Protein_Cycle& ... Saylor.org's Cell Biology. This page may need to be reviewed for quality. ...
  https://en.wikibooks.org/wiki/Saylor.org%27s_Cell_Biology/Trimeric_G_