*  p53 Signaling - QIAGEN
... the genes ATM and ATR are activated and phosphorylate the cell cycle checkpoint proteins CHEK1 and CHEK2. During this process, ... the genes ATM and ATR are activated and phosphorylate the cell cycle checkpoint proteins CHEK1 and CHEK2. During this process, ... Genes targeted by p53 initiate multiple processes such as cell cycle arrest and apoptosis. A wide variety of cancers carry p53 ... Genes targeted by p53 initiate multiple processes such as cell cycle arrest and apoptosis. A wide variety of cancers carry p53 ...
  https://www.qiagen.com/fi/shop/genes-and-pathways/complete-biology-list/p53-signaling/
*  'Addiction' to Cell-cycle Proteins Shuts Down Tumors in Mice:...
... scientists have safely shut down breast cancer and a form of leukemia in mice by targeting abnormal proteins to which the ... that control cells' growth cycle. Many types of cancer have abnormal amounts of the proteins, spurring the cells to grow too ... Addiction' to Cell-cycle Proteins Shuts Down Tumors in Mice: Study. by Rukmani Krishna on October 22, 2012 at 11:31 PM Cancer ... Cyclin proteins act as "checkpoint" guards to control cell's cycle of rest, growth and division. The D-cyclins determine when a ...
  http://www.medindia.net/news/addiction-to-cell-cycle-proteins-shuts-down-tumors-in-mice-study-108903-1.htm
*  "Novel Cell Cycle Proteins In Apicomplexan Parasites" by Carrie Butler
We named the protein inner membrane complex protein 16 (IMC16) due to its IMC localization however; this protein uniquely ... and sorted the resulting set of dual cell cycle regulated orthologs (744 total) into protein pairs conserved across many ... we devised a strategy to identify the core set of apicomplexan cell division cycling genes with important roles in parasite ... Hypothetical proteins comprise roughly half of the predicted gene complement of T. gondii and P. falciparum and represent the ...
  http://scholarcommons.usf.edu/etd/5195/
*  Cell Cycle Protein Expression in Vascular Smooth Muscle Cells In Vitro and In Vivo Is Regulated Through Phosphatidylinositol 3...
... and Rapamycin-Sensitive Induction of Cell Cycle Protein Expression. We postulated that an altered pattern of cell cycle protein ... For example, protein kinase B (Akt) may play a significant role. However, the inhibition of cell cycle protein upregulation ... Cell Cycle Protein Expression in Vascular Smooth Muscle Cells In Vitro and In Vivo Is Regulated Through Phosphatidylinositol 3- ... Cell Cycle Protein Expression in Vascular Smooth Muscle Cells In Vitro and In Vivo Is Regulated Through Phosphatidylinositol 3- ...
  http://atvb.ahajournals.org/content/21/7/1152
*  Cell cycle checkpoint protein, Rad1 (IPR003011) | InterPro | EMBL-EBI
We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their ... InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites ... Cell cycle checkpoint protein, Rad1 (IPR003011). Short name: Cell_cycle_checkpoint_Rad1 ... In Caenorhabditis elegans, the cell cycle checkpoint protein RAD1 homologue mrt-2 has a role in genome stability by promoting ...
  http://www.ebi.ac.uk/interpro/entry/IPR003011
*  CDC20B - Cell division cycle protein 20 homolog B - Homo sapiens (Human) - CDC20B gene & protein
Cell division cycle protein 20 homolog BAdd BLAST. 519. Proteomic databases. PaxDb, a database of protein abundance averages ... Cluster: Cell division cycle protein 20 homolog B. 31. Q86Y33-3. F7GV04. UPI000036D148. UPI0002746305. UPI00027F8351. ... Cluster: Cell division cycle protein 20 homolog B. 125. Q86Y33-3. F7GV04. UPI00027F8351. UPI000036D148. UPI0005F3B731. ... sp,Q86Y33,CD20B_HUMAN Cell division cycle protein 20 homolog B OS=Homo sapiens GN=CDC20B PE=1 SV=3 ...
  http://www.uniprot.org/uniprot/Q86Y33
*  Distinct structural forms of type I collagen modulate cell cycle regulatory proteins in mesangial cells.
Extracellular matrix molecules profoundly regulate cell behavior, including proliferation. In glomerulonephritis, type I ... Blood Proteins / pharmacology. Cell Adhesion / physiology. Cell Cycle Proteins*. Cell Nucleus / enzymology. Cells, Cultured. ... 0/Blood Proteins; 0/Cdkn1b protein, rat; 0/Cell Cycle Proteins; 0/Cyclin E; 0/Integrin alpha1beta1; 0/Integrins; 0/Microtubule- ... Mitogen-Activated Protein Kinase 1 / metabolism. Mitogen-Activated Protein Kinase 3. Mitogen-Activated Protein Kinases / ...
  http://www.biomedsearch.com/nih/Distinct-structural-forms-type-collagen/10972675.html
*  cell cycle checkpoint control protein RAD9A isoform 1 [Homo sapiens] - Protein - NCBI
cell cycle checkpoint control protein RAD9A isoform 1 [Homo sapiens] cell cycle checkpoint control protein RAD9A isoform 1 [ ... This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle ... Protein expression data [Model Organism Protein Expres...] Protein expression data. Model Organism Protein Expression Database ... cell cycle checkpoint control protein RAD9A isoform 1 [Homo sapiens]. NCBI Reference Sequence: NP_004575.1 ...
  https://www.ncbi.nlm.nih.gov/protein/4759022
*  TACC - Cell Cycle - Regulator Proteins - Proteins - Products
Transforming acidic coiled-coil (TACC), an evolutionally conserved protein family, has been shown to be involved in the process ... A small compound targeting TACC3 revealed its different spatiotemporal contributions for spindle assembly in cancer cells. ...
  https://www.axonmedchem.com/products/proteins/regulator-proteins/cell-cycle/tacc
*  Modulation of cell cycle regulatory protein expression and suppression of tumor growth by mimosine in nude mice.
... *Authors: *H ... Chang, H., Weng, C., Yen, M., Chuang, L., Hung, W.'Modulation of cell cycle regulatory protein expression and suppression of ... Chang, H., Weng, C., Yen, M., Chuang, L., Hung, W.'Modulation of cell cycle regulatory protein expression and suppression of ... However, whether mimosine may modulate the expression of these cell cycle regulatory proteins and suppress tumor growth in vivo ...
  https://www.spandidos-publications.com/ijo/17/4/659
*  Cell division cycle protein 73 homolog | definition of Cell division cycle protein 73 homolog by Medical dictionary
What is Cell division cycle protein 73 homolog? Meaning of Cell division cycle protein 73 homolog medical term. What does Cell ... Looking for online definition of Cell division cycle protein 73 homolog in the Medical Dictionary? Cell division cycle protein ... Cell division cycle protein 73 homolog , definition of Cell division cycle protein 73 homolog by Medical dictionary https:// ... redirected from Cell division cycle protein 73 homolog) CDC73. A gene on chromosome 1q25 that encodes a tumour suppressor ...
  https://medical-dictionary.thefreedictionary.com/Cell+division+cycle+protein+73+homolog
*  Expression of Cell-Cycle-regulated Proteins pRb2/p130, p107, p27kip1, p53, mdm-2, and Ki-67 (MIB-1) in Prostatic Gland...
... et al Expression of cell-cycle-associated proteins pRB2/p130 and p27/Kip1 in vulvar squamous cell carcinomas. Hum. Pathol., 32: ... which is involved in cell cycle control and cell differentiation. The RB protein is mutated or absent in a variety of human ... Expression of Cell-Cycle-regulated Proteins pRb2/p130, p107, p27kip1, p53, mdm-2, and Ki-67 (MIB-1) in Prostatic Gland ... Expression of Cell-Cycle-regulated Proteins pRb2/p130, p107, p27kip1, p53, mdm-2, and Ki-67 (MIB-1) in Prostatic Gland ...
  http://clincancerres.aacrjournals.org/content/8/6/1808
*  "Targeting Cell Cycle Proteins in Breast Cancer Cells with siRNA by Usi" by Manoj Parmar, Hamidreza Montazeri Aliabadi et al.
Using a library of siRNAs against cell cycle proteins, we identified cell division cycle protein 20 (CDC20), a recombinase ... MDA-MB-231 and MCF7 cells with respect to another well-studied cell cycle protein, kinesin spindle protein. We also explored ... There was no apparent effect of silencing selected cell cycle proteins on the potency of the chemotherapy drug doxorubicin. The ... The presented study highlighted specific cell cycle protein targets critical for breast cancer therapy, and provided a ...
  http://digitalcommons.chapman.edu/pharmacy_articles/142/
*  Cell cycle checkpoint protein RAD17
... a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein ... The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a ... This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for ... This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. ...
  https://pharos.nih.gov/idg/targets/O75943
*  Cell cycle regulatory protein | definition of Cell cycle regulatory protein by Medical dictionary
Cell cycle regulatory protein explanation free. What is Cell cycle regulatory protein? Meaning of Cell cycle regulatory protein ... Looking for online definition of Cell cycle regulatory protein in the Medical Dictionary? ... The results suggest that maslinic acid induces G1 cell cycle arrest with induction of Gl phase cell cycle regulatory proteins ... Differential effects of cell cycle regulatory protein [p21.. 4A, wild type cells exhibited increased expression of the cell ...
  https://medical-dictionary.thefreedictionary.com/Cell+cycle+regulatory+protein
*  Ccar2 - Cell cycle and apoptosis regulator protein 2 - Mus musculus (Mouse) - Ccar2 gene & protein
Enhances the transcriptional repressor activity of NR1D1 through stabilization of NR1D1 protein levels by preventing its ... Cell cycle and apoptosis regulator protein 2Add BLAST. 922. Amino acid modifications. Feature key. Position(s). Description ... sp,Q8VDP4,CCAR2_MOUSE Cell cycle and apoptosis regulator protein 2 OS=Mus musculus OX=10090 GN=Ccar2 PE=1 SV=2 ... Protein. Similar proteins. Organisms. Length. Cluster ID. Cluster name. Size. Q8VDP4. Q8N163. E2PSM9. A0A2K5F1D7. UPI000B7B6BEA ...
  http://www.uniprot.org/uniprot/Q8VDP4
*  Cell cycle checkpoint protein RAD1
Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is ... This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated ... The DNA binding domain (DBD) within the hLigI catalytic fragment interacts with both PCNA and the heterotrimeric cell-cycle ... to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 ...
  https://pharos.nih.gov/idg/targets/O60671
*  Cell division cycle 7-related protein kinase - Wikipedia
The protein is expressed at constant levels throughout the cell cycle. The gene coding for the Dbf4 or ASK protein is regulated ... Although expression levels of the protein appear to be constant throughout the cell cycle, the protein kinase activity appears ... Cell division cycle 7-related protein kinase is an enzyme that in humans is encoded by the CDC7 gene. The Cdc7 kinase is ... The product encoded by this gene is predominantly localized in the nucleus and is a cell division cycle protein with kinase ...
  https://en.wikipedia.org/wiki/Cell_division_cycle_7-related_protein_kinase
*  Cell division cycle protein 16 homolog
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72 ... a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The ... regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 23 ... The APC complex is a cyclin degradation system that governs exit from mitosis by targeting cell cycle proteins for degredation ...
  https://pharos.nih.gov/idg/targets/Q13042
*  Cell division cycle protein 23 homolog
GO Process for Cell division cycle protein 23 homolog. protein ubiquitination involved in ubiquitin-dependent protein catabolic ... APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72 ... a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting ... a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The ...
  https://pharos.nih.gov/idg/targets/Q9UJX2
*  In vitro toxicity of biomaterials determined with cell density, total protein, cell cycle distribution and adenine nucleotides
Cell density, total protein, total protein per cell, fraction of cells in G0/G1- or S-phase, the concentration of ATP, ADP and ... Cell density, total protein, total protein per cell, fraction of cells in G0/G1- or S-phase, the concentration of ATP, ADP and ... Cell density, total protein, total protein per cell, fraction of cells in G0/G1- or S-phase, the concentration of ATP, ADP and ... Wieslander, Anders P; Nordin, Marika K; Hansson, Björn; Baldetorp, Bo LU and Kjellstrand, Per T T (1993) In Artificial Cells, ...
  https://lup.lub.lu.se/search/publication/472cd146-c1b9-4950-9016-ee935d86ee0a
*  Immunological characterization and localization of cell cycle regulatory proteins in preimplantation mouse embryos
Both cyclin E and CDK2 were not detected in GI or G2/M of the first cell cycle or GI of the second cell cycle.From the ... The gold particles at GI, S, and G2/N4 of the first cell cycle and G1 of the second cell cycle appear to be associated with ... Thus, it was the goal of this study to characterize and localize various cell cycle proteins at specific time points in normal ... Immunological characterization and localization of cell cycle regulatory proteins in preimplantation mouse embryos. Login ...
  http://cardinalscholar.bsu.edu/handle/handle/186398
*  Cytokine Influence on the mRNA of Cell Cycle and ECM Proteins by hRPE Cells In vitro | IOVS | ARVO Journals
... cell cycle proteins and extracellular matrix (ECM) proteins. Methods: Human RPE cells were incubated in the presence of TGFß1, ... M. Hollborn, P. Wiedemann, L. Kohen; Cytokine Influence on the mRNA of Cell Cycle and ECM Proteins by hRPE Cells In vitro . ... Cytokine Influence on the mRNA of Cell Cycle and ECM Proteins by hRPE Cells In vitro ... Cytokine Influence on the mRNA of Cell Cycle and ECM Proteins by hRPE Cells In vitro ...
  https://iovs.arvojournals.org/article.aspx?articleid=2414754
*  Cell-cycle-dependent association of protein phosphatase 1 and focal adhesion kinase | Biochemical Journal
Cell-cycle-dependent association of protein phosphatase 1 and focal adhesion kinase. Marco FRESU, Mariarita BIANCHI, J. Thomas ... Cell-cycle-dependent association of protein phosphatase 1 and focal adhesion kinase ... Cell-cycle-dependent association of protein phosphatase 1 and focal adhesion kinase ... Cell-cycle-dependent association of protein phosphatase 1 and focal adhesion kinase ...
  http://www.biochemj.org/content/358/2/407
*  Compensatory Stabilization of RIIβ Protein, Cell Cycle Deregulation, and Growth Arrest in Colon and Prostate Carcinoma Cells by...
B, cell cycle analysis. In an attempt to synchronize a homogeneous cell population at a particular cell cycle phase, untreated ... Cell Cycle Analysis of LS-174T Cells.. Fixed cells were treated with 1 mg/ml RNase (Sigma Chemical Co., St. Louis, MO) for 30 ... Compensatory Stabilization of RIIβ Protein, Cell Cycle Deregulation, and Growth Arrest in Colon and Prostate Carcinoma Cells by ... Compensatory Stabilization of RIIβ Protein, Cell Cycle Deregulation, and Growth Arrest in Colon and Prostate Carcinoma Cells by ...
  http://clincancerres.aacrjournals.org/content/6/9/3434