Clinical features and outcomes of 25 patients with primary adenosquamous cell carcinoma of the prostate
PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.http://pubmedcentralcanada.ca/pmcc/articles/PMC2994527/
Adenosquamous carcinoma lung - What Does the Doctor Say?
Helpful, trusted answers from doctors: Dr. Holzman on adenosquamous carcinoma lung: There could be genetic component to a squamous cell cancer, although the exact implications on treatment aren't known. Obviously if there is a strong family history of cancers, or if it strikes someone who is young and/or a non smoker/drinker i would suspect a strong genetic contribution. Without more details, it is hard to say with any certainty.https://www.healthtap.com/topics/adenosquamous-carcinoma-lung
BC embraces less-invasive breast biopsy system
Low-Grade Adenosquamous Carcinoma of the Breast Developing Around a Localization Wire Fragment. Handa, Priyanka; Khader, Samer N.; Buchbinder, Shalom S.; Guelfguat, Mark // Laboratory Medicine;Summer2015, Vol. 46 Issue 3, p241 We present the case of a 67-year-old white woman with a history of benign biopsy results in the previous 10 years before she developed low-grade adenosquamous carcinoma around a residual localization wire fragment. A possible theory of carcinogenesis may be related to reparative epithelium in a... ...http://connection.ebscohost.com/c/articles/2451885/bc-embraces-less-invasive-breast-biopsy-system
Desmoglein 3 + Napsin A - Biocare Medical
Desmoglein 3 (DSG3) + Napsin A are very sensitive and specific markers, and may be useful for discriminating between lung SqCC and lung adenocarcinoma. DSG3 is a membrane stain that marks lung SqCC while Napsin A is a cytoplasmic stain that marks lung adenocarcinomas. In the vast majority of lung cancers tested, only a single antibody stain was observed. Coexpression of both antibodies may be observed in adenosquamous cell carcinomas and Napsin A staining is observed in some cases of residual normal lung. In grades 1-2, Desmoglein 3 + Napsin A provide staining sensitivity in the mid 90% range.. Available individually or as part of the PulmoPanel™ Multiplex Kit. Cat No: PPM 436 AAK. ...http://biocare.net/product/desmoglein-3-napsin-a/
Carcinoma of the large bowel in Singapore--a pathological study. | ScholarBank@NUS
Five hundred and sixty-five cases of large bowel cancer were analysed. There were 8 (1.4%) appendiceal tumours, 296 (52.4%) colonic cancers, 236 (41.8%) rectal cancers, 6 (1.1%) anal cancers and 19 (3.4%) multiple primary cancers of the large bowel. Non-mucinous adenocarcinoma was by far the commonest histological type of large bowel cancer (74.7%). This was followed by mucinous carcinoma (20.7%). Other histological types were relatively uncommon. They included carcinoid tumours (1.8%), signet-ring cell carcinoma (1.5%), squamous cell carcinoma (0.7%), undifferentiated carcinoma (0.4%) and adenosquamous carcinoma (0.2%). The proportion of mucinous carcinoma was greater among the Indians and ...http://scholarbank.nus.edu.sg/handle/10635/108038
Adeno carcinoma anal cancer | Cancer Survivors Network
I'm over here from gyn boards but wanted to throw my two cents in on the adeno subject. HPV can cause cancer in the cells of squamous or the glandular adenocarcinoma. I have adenosquamous carcinoma of the cervix, a rare form of cervical cancer but none the less, hpv associated cervical cancer. Most anal cancers are also hpv related. The probable reason for the more drastic surgical approach is because theadenocarcinomas tend to behave more aggressively than the squamous, and are more resistant to chemo and radiation. They require a more aggressive treatment plan to eliminate and control. I had a radical hysterectomy, chemo, chemo/rads and more chemo and still had a recurrence in the lung two months after completing treatment. I was originally staged at 2a. Had more surgery and chemo and am now NED. I would support the surgery to remove the ...https://csn.cancer.org/node/259289
DMOZ - Health: Conditions and Diseases: Cancer: Lung: Non-Small Cell
One of two basic types of lung cancer. Non-small cell tumors grow slowly but are less likely to respond to chemotherapy. There are different subtypes of non-small cell lung cancer: adenocarcioma, squamous cell carcinoma, adenosquamous carcinoma, larger cell carcinoma, and undifferentiated carcinoma.http://dmoztools.net/Health/Conditions_and_Diseases/Cancer/Lung/Non-Small_Cell/
NutritionMD.org :: Cervical Cancer
Cervical cancer occurs primarily in 2 varieties: squamous cell carcinoma (about 80% of cases) and adenocarcinoma (about 15%). Adenosquamous carcinoma makes up most of the remaining cases, and this type may have a poorer outcome. A rare cause of death when screening programs exist, cervical cancer accounts for about 1% of all cancer deaths in developed countries. Cervical cancer is age related; incidence is extremely low in women under 20, and peaks at 16.5/100,000/year in women aged 45 to 49.1. Symptoms are absent in many cases, but abnormal vaginal discharge or bleeding often occurs. Advanced disease may also cause pain in the low back and pelvis with radiation into the posterior legs, as well as bowel or urinary symptoms such as passage of blood and a sensation of pressure. ...http://www.nutritionmd.org/health_care_providers/oncology/cervical_cancer.html
ClinMed International Library
Squamous cell carcinoma is the most common type of cervical cancer, followed by adenocarcinoma, adenosquamous carcinoma, and neuroendocrine carcinomas.https://www.clinmedjournals.org/articles/ogcr/ogcr-2-050.php?jid=ogcr
Lirias: Papillomavirus infections
Papillomas or warts are easily recognized skin or mucous membrane tumors. They are common in wild species and are particularly well known in deer (Cosgrove and Fay 1981; Sundberg and Nielson 1981). Most of these tumors are caused by papillomaviruses (PVs). Tumors can become quite large and numerous and persist for prolonged periods, but they usually regress, providing the individual with long-term immunity to future infections. Occasionally, the tumors will progress to squamous cell carcinoma, adenosquamous carcinoma, or sebaceous carcinoma that will eventually kill the host if not treated. Specific mucosotropic PV types and those infecting immunodeficient individuals are prone to induce malignancies. Virtually all mammalian species are hosts for one of more PV. This chapter provides an overview of PV infections in mammals ...https://lirias.kuleuven.be/handle/123456789/161983
Design, synthesis, and biological evaluation of NAD(P)H: quinone oxidoreductase (NQO1)-targeted oridonin prodrugs possessing...
The enzyme NQO1 is a potential target for selective cancer therapy due to its overexpression in certain hypoxic tumors. A series of prodrugs possessing a variety of cytotoxic diterpenoids (oridonin and its analogues) as the leaving groups activated by NQO1 were synthesized by functionalization of 3-(hydroxymethyl)indolequinone, which is a good substrate of NQO1. The target compounds (29a-m) exhibited relatively higher antiproliferative activities against NQO1-rich human colon carcinoma cells (HT-29) and human lung carcinoma (A549) cells (IC50 ¼ 0.263e2.904 mM), while NQO1-defficient lung adenosquamous carcinoma cells (H596) were less sensitive to these compounds, among which, compound 29h exhibited the most potent antiproliferative activity against both A549 and HT-29 ...http://eprints.nottingham.ac.uk/42902/
Letrozole in Treating Women With Recurrent or Metastatic Endometrial Cancer - Full Text View - ClinicalTrials.gov
DISEASE CHARACTERISTICS: Histologically proven, recurrent or metastatic, adenocarcinoma or adenosquamous carcinoma of the endometrium not curable by surgery and/or radiotherapy Failed one prior progestin therapy for advanced/metastatic disease OR Considered for letrozole as first line therapy of advanced/metastatic disease No clear cell or papillary serous histology, uterine sarcomas, mixed muellerian tumors, and/or adenosarcomas At least one site of measurable disease by clinical exam, CT, or MRI scan Bone lesion(s) are not considered measurable No CNS metastases. PATIENT CHARACTERISTICS: Age: 18 and over Performance status: ECOG 0-2 Menopausal status: Postmenopausal (surgical or natural) Life expectancy: At least 12 weeks Hematopoietic: Absolute granulocyte count at least 1,500/mm3 Platelet count at least 100,000/mm3 Hepatic: Bilirubin less than upper limit of normal (ULN) AST or ALT no ...https://clinicaltrials.gov/ct2/show/NCT00004251
CiNii 論文 - Adenosquamous carcinoma of the gall-bladder with gastric foveolar-type epithelium ...
真木 健裕 , 原 敬志 , 平野 聡 , 田中 栄一 , 斉藤 克憲 , 竹内 幹也 , 七戸 俊明 , 佐藤 幸作 , 三品 壽雄 , 近藤 哲 日本消化器外科学会雑誌 40(11), 1811-1815, 2007-11-01 CiNii PDF - オープンアクセス 医中誌Web 参考文献19件 被引用文献2件 ...http://ci.nii.ac.jp/naid/10008329490
High stromal versican expression predicts unfavourable outcome in oral squamous cell carcinoma | Journal of Clinical Pathology
Background: Versican, an extracellular matrix proteoglycan, has been noted to be expressed in several malignant tumours and has been suggested to play an important role in cancer development and tumour growth.. Aims: To investigate whether the versican expression level in the peritumoural stromal tissue of primary oral squamous cell carcinoma (OSCC) predicts relapse-free or disease-specific survival. Also, to study the associations between versican expression and several other clinicopathological variables, as well as tumour cell proliferation.. Methods: Immunohistochemistry was used to study the expression of versican and tumour cell proliferative activity in 139 OSCCs. All pertinent clinical data were collected retrospectively from the hospital records.. Results: In this cohort, versican expression did not correlate with the ...http://jcp.bmj.com/content/60/3/267.full
Study of Velcade and Irinotecan in Advanced Cervical, Vulvar, or Vaginal Cancer - Full Text View - ClinicalTrials.gov
This is a phase 2 study. Patients with advanced or metastatic histologically documented squamous cell carcinoma, adenocarcinoma, or adenosquamous cancers originating in the cervix, vagina, or vulva will be eligible. Measurable disease by either clinical exam or radiography is also required. Patients receiving cisplatin-based chemoradiation as definitive treatment for local disease will be eligible. Patients must have no more than one prior platinum-based chemotherapy regimen in the metastatic setting. Patients presenting with distant metastatic disease (beyond the pelvis) will be eligible, as long as they are not eligible for a higher priority study ...https://clinicaltrials.gov/ct2/show/NCT00106262?term=vaginal+cancer&rank=8
Laparoscopic vs Abdominal Radical Hysterectomy In Patients With Early Cervical Cancer - Full Text View - ClinicalTrials.gov
Background: Radical hysterectomy with pelvic lymphadenectomy is one of the FIGO (International Federation of Gynecology and Obstetrics) recommended treatments for early cervical cancer. The objective of this study was to compare radical hysterectomy by laparoscopic approach and open radical hysterectomy in a single center randomized clinical trial. Nevertheless, there are no finished randomized controlled trials comparing laparoscopic radical hysterectomy and abdominal radical hysterectomy although there is an ongoing trial.. Methods: Were enrolled 30 IA2 with lymph vascular space invasion and IB cervical cancer patients. Postoperative pain intensity was defined as primary endpoint and pain intensity was measured by a 10-point numeric rating scale. Secondary outcomes were: intraoperative and other postoperative outcomes, histopathological outcomes and 5-year follow-up. Data analysis is being done at this moment ...https://clinicaltrials.gov/ct2/show/NCT01258413
Poorly differentiated colonic adenocarcinoma, medullary type: clinical, phenotypic, and molecular characteristics. - Semantic...
Clinicopathological evidence has accumulated that colorectal adenocarcinoma with minimal or no glandular differentiation constitutes two entities with different prognosis. In a series of 20 predominantly nonglandular, poorly differentiated adenocarcinomas, histological features, DNA content, p53 protein expression, Ki-ras mutation, and microsatellite instability were analyzed and correlated to the biology of the tumors. In addition, the presence of Epstein-Barr virus (EBV) transcripts was tested by RNA in situ hybridization and EBV DNA was demonstrated by nested polymerase chain reaction. Histologically, 13 tumors showed small uniform cells and 7 tumors showed large pleomorphic cells. Tumors with uniform cells exhibited more commonly an expansive growth pattern (69.2% versus 0%; P | 0.025) and a dense peritumor lymphoid ...https://www.semanticscholar.org/paper/Poorly-differentiated-colonic-adenocarcinoma-medul-Rueschoff-Dietmaier/0df635c509061927ae6eae267819f4156af298e5
"Human MUC1 Mucin: A Potent Glandular Morphogen" by Mark J. Hudson, Gordon W. Stamp et al.
Human MUC1 mucin is a high-molecular-weight transmembrane glycoprotein, which is apically expressed in the majority of glandular epithelia. During embryonic development, changes in the pattern of MUC1 mucin expression coincide with the onset of glandular differentiation. This mucin is also frequently overexpressed and aberrantly glycosylated in carcinomas. To investigate the potential role of MUC1 mucin in morphogenesis, a full length MUC1 cDNA was transfected into murine mammary adenocarcinoma (410.4) and Madin-Darby canine kidney (MDCK) cells. This generated four clonal cell lines. Western blotting, FACS analysis, and immunohistochemistry confirmed expression of MUC1. All four MUC1-expressing clones demonstrated altered morphogenesis when cultured in three-dimensional type I collagen gels. While parental and vector control 410.4 ...http://ecommons.aku.edu/pakistan_fhs_mc_pathol_microbiol/360/
Highly invasive carcinomas of the urinary bladder were induced in male C57BL/6 × DBA/2 F1 (hereafter called B6D2F1) mice by gastric intubation of N-butyl-(4-hydroxybutyl)nitrosamine (OH-BBN) using a quantitative dosing schedule. Animals received either 5 or 10 mg OH-BBN per intubation, two times each week, for 9 weeks for a total dose of either 90 or 180 mg, and they were killed 6 months after the first carcinogen intubation. Seven days after the final intubation of OH-BBN, animals were fed either a placebo diet or diet supplemented with either 150 or 200 mg 13-cis-retinoic acid per kg of diet. A 41 and 43% incidence of urinary bladder cancer was observed in mice given the low and high dose of carcinogen, respectively, and fed a placebo diet. Sixty-seven % of the carcinomas induced in these animals invaded either into or through the urinary bladder wall. Varying degrees of transitional and either squamous or ...http://cancerres.aacrjournals.org/content/41/3/927
Vajtai, I; Varga, Z; Aguzzi, A (1997). Pleomorphic xanthoastrocytoma with gangliogliomatous component. Pathology, Research and Practice, 193(9):617-621.. Vajtai, I; Varga, Z; Aguzzi, A (1996). MIB-1 immunoreactivity reveals different labelling in low-grade and in malignant epithelial neoplasms of the choroid plexus. Histopathology, 29(2):147-151.. Varga, Z; Vajtai, I; Aguzzi, A (1996). The standard isoform of CD44 is preferentially expressed in atypical papillomas and carcinomas of the choroid plexus. Pathology, Research and Practice, 192(12):1225-1231.. Varga, Z; Vajtai, I; Marino, S; Schäuble, B; Yonekawa, Y; Aguzzi, A (1996). Tubular adenoma of the choroid plexus: evidence for glandular differentiation of the neuroepithelium. Pathology, Research and Practice, 192(8):840-844.. ...http://www.zora.uzh.ch/view/authors_for_linking_in_citation/Vajtai=3AI=3A=3A.html
An unusual case of glandular schwannoma.
Glandular differentiation is exceedingly rare in peripheral nerve sheath tumors. In this report, an exceptional case of retroperitoneal glandular schwannoma is described in which the glandular element is markedly atypical, whereas the schwannian comphttp://www.biomedsearch.com/nih/unusual-case-glandular-schwannoma/17258283.html
Tissue expression of ANLN - Staining in oral mucosa - The Human Protein Atlas
Expression of ANLN (ANILLIN, scra, Scraps) in oral mucosa tissue. Antibody staining with HPA005680, HPA050556, CAB033902 and CAB062547 in immunohistochemistry.http://www.proteinatlas.org/ENSG00000011426-ANLN/tissue/oral+mucosa
Tissue expression of ANLN - Staining in spleen - The Human Protein Atlas
Expression of ANLN (ANILLIN, scra, Scraps) in spleen tissue. Antibody staining with HPA005680, HPA050556, CAB033902, CAB062547 and CAB068175 in immunohistochemistry.http://www.proteinatlas.org/ENSG00000011426-ANLN/tissue/spleen
FIAF - International Federation of Film Archives
The International Federation of Film Archives (FIAF) brings together institutions dedicated to rescuing of films both as art and as historical documentshttp://www.fiafnet.org/pages/E-Resources/FIAF-Statutes-and-Rules.html