Transitional Cell Carcinoma - Mar Vista Animal Medical Center
The transitional cell carcinoma is a particularly unpleasant tumor of the urinary bladder. In dogs, it usually arises in the ... The transitional cell carcinoma (frequently abbreviated "TCC") is a particularly unpleasant tumor of the urinary bladder. In ... About 30% of transitional cell carcinomas will shed tumor cells into the urine which may be identified as such on the ... A Transitional Cell Carcinoma is a tumor of the Transitional Cell lining of the urinary bladder. ...http://marvistavet.com/transitional-cell-carcinoma.pml
Diagnostic Imaging Scientific Publications - Andrew Parry, Lizza Baines, Sally Birch, Luis Mesquita, Andrew Tanner
This case is unusual as urethral tumours are usually transitional cell carcinomas and frequently present with signs of dysuria. ... Radiographic Appearance of an Osseous Metastasis to the Distal Radius from a Transitional Cell Carcinoma of the Urinary Bladder ... Lascelles, B.D.X., Parry, A.T., Stidworthy, M.F., Dobson, J.M., White, R.A.S., (2000) Squamous cell carcinoma of the nasal ... Squamous cell carcinoma of the nasal planum was diagnosed in 17 dogs over a period of 11 years. Ulceration, bleeding and ...https://www.willows.uk.net/veterinary-professionals/scientific-publications/diagnostic-imaging
KIAA 1096, a Gene on Chromosome 1q, is Amplified and Overexpressed in Bladder Cancer
... is located in the 9p21 chromosomal region that is frequently deleted in human bladder transitional cell carcinomas (TCCs). The ... Factors enhancing the risk of bladder cancer; Examination of the ABO antigens and HLA antigens in patients with cell carcinoma ... KIAA1096 expression in nonmalignant bladder mucosa tissue but apparent upregulation in invasive transitional cell carcinoma. ... p15INK4b in bladder carcinomas: decreased expression in superficial tumours. Le Frère-Belda, M A; Cappellen, D; Daher, A; Gil- ...http://connection.ebscohost.com/c/articles/7738497/kiaa-1096-gene-chromosome-1q-amplified-overexpressed-bladder-cancer
Learn details of the urothelial carcinoma treatment market trends and key developments - WhaTech
... frequently papillary. These carcinomas are classified according to the degree of anaplasia. ... Urothelial carcinoma is a malignant neoplasm resulting from transitional epithelium, occurring mainly in the urinary bladder, ... Urothelial cell carcinoma is also known as transitional cell carcinoma. Bladder transitional cell carcinoma (TCC) is the most ... Radiotherapy is not frequently used for transitional cell carcinoma of the kidney or ureter. ...https://www.whatech.com/market-research/industrial/349899-learn-details-of-the-urothelial-carcinoma-treatment-market-trends-and-key-developments
Bladder Cancer in Dog
... with cancer frequently moving to associated lymph nodes andthe lungs.Along with transitional cell carcinomas, other types of ... Transitional cell carcinoma is the most common type of dog bladder cancer, but it is possible that other benign and malignant ... Transitional cell carcinomas are the most commontype ofbladder cancer. These may occur either as a single mass on the ... Transitional cell carcinomas usually occur at the part ofthe canine bladder called the trigone ofthe bladder. ...http://www.dog-health-guide.org/bladder-cancer-in-dog.html
Patent US6280742 - Methods and materials for the treatment of prostatic carcinoma - Google Patents
... carcinoma via the administration of disclosed compositions, immunotherapeutic agents, or antibodies. ... The remaining prostatic cancers are divided among squamous cell and transitional cell carcinomas that arise in the prostatic ... Kong, D. et al., "PTEN1 is frequently mutated in primary endometrial carcinomas," Nature Genetics, 17:143-144 (Oct., 1997).. ... on the proliferation of human prostatic carcinoma cells, cell lines LnCap and Du145, were plated (104 per ml) in 96-well tissue ...http://www.google.com/patents/US6280742?dq=645576
Bladder Cancer - A Woman's Health - Women Magazine
... of all bladder cancers and these are referred to as transitional cell carcinomas. Because transitional cell carcinomas are the ... stage 0 transitional bladder cancer is pathologically classified as either noninvasive papillary carcinoma or carcinoma in situ ... Bladder cancer occurs predominantly in elderly men and less frequently in women and younger men. Many bladder cancers are ... The wall of the bladder is lined with several layers of cells called transitional cells. Cancer arising from these cells makes ...http://awomanshealth.com/conditions-treatments/bladder-cancer/
Phase II study of everolimus in patients with locally advanced or metastatic transitional cell carcinoma of the urothelial ... Components of the PI3K/Akt/mTOR pathway are frequently mutated or altered in bladder cancer, leading to hyperactive mTOR ... Tumors were classified into noninvasive TCC (CIS) or invasive carcinomas (lamina propria invasive and muscularis propria ... of an oncogene in transgenic mice induced the formation of carcinoma in situ and invasive transitional cell carcinoma. Cancer ...http://cancerpreventionresearch.aacrjournals.org/content/9/1/53
MR imaging bladder - Sumer's Radiology Blog
... small cell carcinoma, and carcinosarcoma. Squamous cell carcinoma Squamous cell carcinoma is the most common non-transitional- ... but few clues may lead to the differentiation of transitional from non-transitional-cell carcinomas. Non-transitional-cell ... They are most frequently observed in the female genital tract.31 Neither the etiology nor the pathogenesis of carcinosarcomas ... whereas two thirds of transitional cell carcinomas are superﬁcial. Non-transitional-cell carcinomas tend to cause marked ...http://sumerdoc.blogspot.com/2004/10/mr-imaging-bladder.html
Bladder Cancer | Nebraska Hematology Oncology - Cancer Care Treatment Blood Disorders Clinical Trials Lincoln Nebraska (NE)
... of all bladder cancers and these are referred to as transitional cell carcinomas. Because transitional cell carcinomas are the ... stage 0 transitional bladder cancer is pathologically classified as either noninvasive papillary carcinoma or carcinoma in situ ... Bladder cancer occurs predominantly in elderly men and less frequently in women and younger men. Many bladder cancers are ... The wall of the bladder is lined with several layers of cells called transitional cells. Cancer arising from these cells makes ...https://www.yourcancercare.com/types-of-cancer/bladder-cancer
SLC7A5 - Wikipedia
2007). "Expression of LAT1 predicts risk of progression of transitional cell carcinoma of the upper urinary tract". Virchows ... 2009). "L-type amino acid transporter 1 (LAT1) is frequently expressed in thymic carcinomas but is absent in thymomas". J Surg ... Shennan DB, Thomson J (2008). "Inhibition of system L (LAT1/CD98hc) reduces the growth of cultured human breast cancer cells". ... 2005). "High expression of L-type amino acid transporter 1 in infiltrating glioma cells". Brain Tumor Pathol. 22 (2): 89-91. ...https://en.wikipedia.org/wiki/SLC7A5
Cancer of urinary bladder | definition of cancer of urinary bladder by Medical dictionary
The majority of bladder malignancies are transitional cell carcinomas; a small percentage are squamous cell carcinomas or ... In North and South America, Europe, and Asia, transitional cell carcinoma is the most common type of bladder cancer. ... Gross, painless, intermittent hematuria is the most frequently reported symptom. Occult blood may be discovered during a ... are urothelial or transitional cell carcinomas arising in the epithelial layer of the bladder, although squamous cell (4%), ...https://medical-dictionary.thefreedictionary.com/cancer+of+urinary+bladder
Urothelial Tumors of the Renal Pelvis and Ureters: Problem, Epidemiology, Etiology
Distribution of upper tract transitional cell carcinoma. Rates of distribution for transitional cell carcinoma are 58% for the ... Squamous cell carcinoma comprises 1-7% of upper tract urothelial tumors. Squamous cell carcinoma is frequently associated with ... Eltz S, Comperat E, Cussenot O, Rouprêt M. Molecular and histological markers in urothelial carcinomas of the upper urinary ... The incidence of transitional cell carcinoma (TCC) increases with age. The peak incidence is in those in their 70s and 80s. ...https://emedicine.medscape.com/article/452449-overview
Diagnostic value of MUC4 immunostaining in distinguishing epithelial mesothelioma and lung adenocarcinoma - PDF
Carcinomas with squamous differentiation and transitional cell carcinomas are diffusely positive. 19 The second one, calretinin ... Renal Cell Carcinoma: Advances in Diagnosis B. Iványi, MD Renal Cell Carcinoma: Advances in Diagnosis B. Iványi, MD Department ... Although we have frequently observed both membrane and cytoplasmic immunostaining for MUC4 in carcinomas, some specimens have ... 7 156 matrix cell adhesion in cancer cells 46 and to block immune cell killing of mucin-expressing tumor cells. 47 Moreover, ...http://docplayer.net/1702548-Diagnostic-value-of-muc4-immunostaining-in-distinguishing-epithelial-mesothelioma-and-lung-adenocarcinoma.html
Epithelial cell adhesion molecule - Wikipedia
EpCAM is frequently upregulated in carcinomas but is not expressed in cancers of non-epithelial origin. In cancer cells, EpCAM ... 2004). "The carcinoma-associated antigen EpCAM upregulates c-myc and induces cell proliferation". Oncogene. 23 (34): 5748-58. ... EpCAM is expressed on the basolateral membrane of all simple (especially glandular), pseudo-stratified, and transitional ... 1997). "Epithelial cell adhesion molecule (Ep-CAM) modulates cell-cell interactions mediated by classic cadherins". J Cell Biol ...https://en.wikipedia.org/wiki/Epithelial_cell_adhesion_molecule
Ovarian cancer - Wikipedia
... it must have Brenner tumor foci and transitional cell carcinoma. The transitional cell carcinoma component is typically poorly ... Clear-cell adenocarcinomas are histopathologically similar to other clear cell carcinomas, with clear cells and hobnail cells. ... Japanese women develop clear-cell ovarian cancer more frequently than other groups of women. ... The most common malignancy is squamous cell carcinoma, but adenocarcinoma, basal-cell carcinoma, carcinoid tumor, ...https://en.wikipedia.org/wiki/Ovarian_cancer
Urothelium - Wikipedia
... clear cell (glycogen-rich) variant Urothelial carcinoma, lipoid cell variant Urothelial carcinoma with syncitiotrophoblastic ... Cancers that originate in epithelial cells are termed carcinomas, and they are characterized as having lost the mature, ... Urothelium (or uroepithelium) is an example of transitional epithelium. It is the type of epithelium that lines much of the ... During hydrodistention of the bladder, small petechial hemorrhages (aka glomerulations) are frequently found throughout the ...https://en.wikipedia.org/wiki/Urothelium
Endometrial cancer - Wikipedia
Histologically, TCCE resembles endometrioid carcinoma and is distinct from other transitional cell carcinomas. In contrast to ... Endometrial cancer frequently metastasizes to the ovaries and Fallopian tubes when the cancer is located in the upper part of ... Non-metastatic squamous cell carcinoma and transitional cell carcinoma are very rare in the endometrium. Squamous cell ... Papillary serous carcinoma, clear cell carcinoma, and endometrioid carcinoma are the subtypes at the highest risk of recurrence ...https://en.wikipedia.org/wiki/Endometrial_cancer
List of cancer types - Wikipedia
Ovarian germ cell tumor Penile cancer Renal cell carcinoma Renal pelvis and ureter, transitional cell cancer Prostate cancer ... For example, a benign tumor of smooth muscle cells is called a leiomyoma (the common name of this frequently occurring benign ... Nearly all cancers developing in the breast, prostate, lung, pancreas, and colon are carcinomas. Sarcoma: Cancers arising from ... such as giant cell carcinoma, spindle cell carcinoma, and small-cell carcinoma. Chondrosarcoma Ewing's sarcoma ...https://en.wikipedia.org/wiki/List_of_cancer_types
Surface epithelial-stromal tumor - Wikipedia
This group consists of serous, mucinous, endometrioid, clear cell, and brenner (transitional cell) tumors, though there are a ... 15-30% of endometrioid carcinomas occur in individuals with carcinoma of the endometrium, and these patients have a better ... mucinous tumors are less frequently bilateral, approximately 5% of primary mucinous tumors are bilateral. May form very large ... Bakhru, Arvind; Liu, J. Rebecca; Lagstein, Amir (2012). "A case of small cell carcinoma of the ovary hypercalcemic variant in a ...https://en.wikipedia.org/wiki/Surface_epithelial-stromal_tumor
Ochratoxin A - Wikipedia
... so a relationship between ochratoxin A and renal cell carcinoma has not been found. However, the incidence of transitional cell ... and produced renal adenomas and carcinomas in male mice and in rats (carcinomas in 46% of males and 5% of females). In humans, ... it is frequently written that dietary pattern might decrease or increase the risk of RCC. A Uruguayan case-control study ... Although ochratoxin A is not held as of today as responsible for renal cell carcinoma (RCC), the most frequent renal cancer, ...https://en.wikipedia.org/wiki/Ochratoxin_A
Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Pipeline Review, H1 2014 | Jun 30, 2014 - ReleaseWire
Press Release issued Jun 30, 2014: Reportstack, provider of premium market research reports announces the addition of Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Pipeline Review, H1 2014 market report to its offering Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Pipeline Review, H1 2014http://www.sbwire.com/press-releases/transitional-cell-carcinoma-urothelial-cell-carcinoma-pipeline-review-h1-2014-524975.htm
Two Molecular Pathways to Transitional Cell Carcinoma of the Bladder | Cancer Research
Noninvasive transitional cell carcinomas of the bladder can have two distinct morphologies suggesting they contain different genetic alterations. Papillary transitional cell carcinomas (Ta tumors) are often multifocal and only occasionally progress, whereas flat tumors (carcinomas in situ, CIS), frequently progress to invasive disease. We examined 216 bladder tumors of various stages and histopathologies for two genetic alterations previously described to be of importance in bladder tumorigenesis. Loss of heterozygosity of chromosome 9 was observed in 24 of 70 (34%) Ta tumors but was present in only 3 of 24 (12%) CIS and dysplasia lesions (P = 0.04). In contrast, only 1 of 36 (3%) Ta tumors contained a p53 gene mutation compared to 15 of 23 (65%) CIS and dysplasias (P , 0.001), a frequency ...http://cancerres.aacrjournals.org/content/54/3/784.long
Phase I Study With Sorafenib in Addition to Vinflunine in Metastatic Transitional Cell Carcinoma of the Urothelial Tract - Full...
history of serious or concurrent illness or uncontrolled medical disorder; any medical condition that might be aggravated by treatment or which could not be controlled: active infection requiring antibiotics within 2 weeks before the study inclusion, unstable diabetes mellitus, uncontrolled hypercalcaemia ,2.9 mmol/L (or ,G2 NCI CTCAE v4.0), concurrent congestive heart failure NYHA (class III-IV) or any type of angina pectoris and/or a diagnosis of myocardial infarction during the previous 6 months and/or poorly controlled hypertension will be excluded, QTc ,450 ms at baseline, additional risk factors for Torsade de Pointes (heart failure and hypokalemia (≥G1, i.e. P-K ,LLN-2.5 mM) or family history of long QT-syndrome), cardiac arrhythmias requiring anti-arrhythmics (excluding beta-blockers or digoxin for chronic atrial fibrillation ...https://clinicaltrials.gov/ct2/show/NCT01844947?recr=Open&cond=%22Ureteral+Neoplasms%22&rank=6
Everolimus (RAD001) in Metastatic Transitional Cell Carcinoma of the Urothelium - No Study Results Posted - ClinicalTrials.gov
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details ...https://clinicaltrials.gov/ct2/show/results/NCT00805129?term=NCT00805129&rank=1
Cabazitaxel in Platinum Pre-treated Patients With Locally Advanced or Metastatic Transitional Cell Carcinoma Who Developed...
This trial will compare the efficacy and safety of cabazitaxel and best supportive care (single agent chemotherapy), in patients with locally advanced orhttp://adisinsight.springer.com/trials/700222234
Broccoli Sprout Extract in Treating Patients With Transitional Cell Bladder Cancer Undergoing Surgery
Rationale: Broccoli sprout extract contains ingredients that may prevent or slow the growth of certain cancers. Purpose: This phase I trial is sthttp://www.knowcancer.com/cancer-trials/NCT01108003/
Broccoli Sprout Extract in Treating Patients With Transitional Cell Bladder Cancer Undergoing Surgery - Study Results -...
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details ...https://clinicaltrials.gov/ct2/show/results/NCT01108003?term=NCT01108003&rank=1
Intravesical foreign body and transitional cell carcinoma in a dog | Veterinary Record Case Reports
A nine-year-old chemically neutered male hovawart was referred due to dysuria, stranguria, haematuria and inappetence. Initial examinations suggested a transitional cell carcinoma of the urinary bladder with pulmonary metastases and ureteral ectopia. To confirm the diagnosis and rule out possible ureteral ectopia, cystoscopy was performed. Transitional cell carcinoma was confirmed, and a urethral foreign body was revealed. After successful removal, the foreign body turned out to be a 17-cm long piece of a urinary catheter. The dog's clinical signs ceased completely a few days after extraction of the foreign object and palliative therapy with meloxicam. Approximately four weeks later its condition deteriorated and the owner elected euthanasia. ...http://vetrecordcasereports.bmj.com/content/3/1/e000244
Family Caregiver Palliative Care Intervention in Supporting Caregivers of Patients With Stage II-IV Gastrointestinal,...
Healthy Subject Localized Transitional Cell Cancer of the Renal Pelvis and Ureter Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter Psychosocial Effects of Cancer and Its Treatment Recurrent Bladder Cancer Recurrent Cervical Cancer Recurrent Colon Cancer Recurrent Gastric Cancer Recurrent Ovarian Epithelial Cancer Recurrent Ovarian Germ Cell Tumor Recurrent Pancreatic Cancer Recurrent Rectal Cancer Recurrent Renal Cell Cancer Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter Recurrent Urethral Cancer Recurrent Uterine Sarcoma Regional Transitional Cell Cancer of the Renal Pelvis and Ureter Stage II Bladder Cancer Stage II Renal Cell Cancer Stage II Urethral Cancer Stage IIA ...https://clinicaltrials.gov/ct2/show/NCT01846520?recr=Open&cond=%22Urethral+Diseases%22&rank=3
Top Transitional Cell Carcinoma Hospitals in Gurgaon | Credihealth
View details of top transitional cell carcinoma hospitals in Gurgaon. Get guidance from medical experts to select best transitional cell carcinoma hospital in Gurgaonhttps://www.credihealth.com/hospitals/gurgaon/transitional-cell-carcinoma
Top Transitional Cell Carcinoma Hospitals in Thane | Credihealth
View details of top transitional cell carcinoma hospitals in Thane. Get guidance from medical experts to select best transitional cell carcinoma hospital in Thanehttps://www.credihealth.com/hospitals/thane/transitional-cell-carcinoma
Transitional Cell Carcinoma (Urothelial Cell Carcinoma) - Pipeline Review, H1 2015 | Global Market Research Reports
This report provides comprehensive information on the therapeutic development for Transitional Cell Carcinoma (Urothelial Cell Carcinoma), complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases.http://www.gosreports.com/transitional-cell-carcinoma-urothelial-cell-carcinoma-pipeline-review-h1-2015/
Transitional Cell Carcinoma of the Urinary Tract in Dogs | petMD
Transitional cell carcinoma (TCC) is a malignant (aggressive) and metastasizing (spreading) cancer arising from the transitional epithelium - the highly stretchable lining of the urinary tract system - of the kidney, ureters (the tubes that carry fluid from the kidneys to the bladder), urinary bladder, urethra (the tube that carries urine from the bladder to the outside), prostate, or vagina.http://www.petmd.com/dog/conditions/cancer/c_dg_urinary_carcinoma?page=show
Transitional cell carcinoma - urinary bladder | Voxelz
Focal exophytic growth with signal intensity similar to urinary bladder wall is seen arising from right posterolateral wall approximately 2cm cranial to right vesicoureteric junction. It shows diffusion restriction and enhances in post gadolinium administration.. Cystoscopic biopsy was done and histopathological report turned out to be grade I transitional cell carcinoma.. ...https://voxelz.me/2017/04/29/transitional-cell-carcinoma-urinary-bladder/
Urinary Cytokeratin 20 as a Marker for Transitional Cell Carcinoma - Abstract - European Urology 2000, Vol. 37, No. 5 - Karger...
|b|Objectives:|/b| To determine if detection of cytokeratin 20 (CK20) gene expression, by reverse transcriptase-polymerase chain reaction (RT-PCR) in urine from transitional cell carcinomahttps://www.karger.com/Article/Abstract/20199
Transitional cell carcinoma: a case for collaboration. | Journal of Clinical Pathology
Urine samples from the greatest proportion of the numerical workload of most clinical microbiology laboratories. During the screening by microscopy, atypical cells were detected which did not conform to the normal cellular morphology found in urinary deposits. These specimens were referred to the Department of Cytopathology for a second opinion. From these referrals a small but significant number of previously undiagnosed transitional cell carcinomas were detected.. ...http://jcp.bmj.com/content/45/1/80
Misdiagnosis of Transitional cell carcinoma - RightDiagnosis.com
Misdiagnosis of Transitional cell carcinoma including hidden diseases, diagnosis mistakes, alternative diagnoses, differential diagnoses, and misdiagnosis.http://www.rightdiagnosis.com/t/transitional_cell_carcinoma/misdiag.htm
We report the development of a clonogenic assay for progenitor cells in transitional cell carcinoma of the bladder. Colony growth has been demonstrated from cells obtained both from surgical biopsies and from bladder barbotages. Electron microscopic and karyotypic evidence supports the contention that these progenitors represent a part of the population maintaining the tumor in vivo.. Colony growth occurred in 9 of 11 surgical biopsy samples and in 6 of 6 bladder barbotage samples. Plating efficiency ranged up to 0.7%, and colony size was in some instances greater than 1000 cells.. The assay appears potentially useful for analysis of the biology of human transitional cell carcinoma.. ...http://cancerres.aacrjournals.org/content/39/12/5051
'carcinoma non small cell lung' Protocols and Video...
Video articles in JoVE about carcinoma non small cell lung include 'Isolation and Characterization of Neutrophils with Anti-Tumor Properties', 'Multiplexed Immunofluorescence Analysis and Quantification of Intratumoral PD-1+ Tim-3+ CD8+ T Cells', 'Long-term High-Resolution Intravital Microscopy in the Lung with a Vacuum Stabilized Imaging Window', 'Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors', 'A Portal Vein Injection Model to Study Liver Metastasis of Breast Cancer', 'A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies', 'Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development', 'Ex vivo Live ...https://www.jove.com/keyword/carcinoma+non+small+cell+lung
Positron emission tomography with L-methyl-11C-methionine in the monitoring of therapy response in muscle-invasive transitional...
OBJECTIVE:. To investigate whether positron emission tomography (PET) with L-methyl-11C-methionine as a tracer could be used for diagnostic purposes and for evaluation of therapy in patients with varying stages of urinary bladder cancer treated with chemotherapy.. PATIENTS AND METHODS:. PET was employed in 44 separate examinations involving 29 patients (24 men and five women with a median age of 68 years [mean 66, range 47-78]) with localized or metastatic transitional cell carcinoma of the urinary bladder. In four patients PET examinations were performed prior to the commencement of chemotherapy, and after one course and after three courses.. RESULTS:. The diagnostic accuracy of PET was poor. The technique did not monitor the therapeutic effect of neoadjuvant chemotherapy, producing results that correlated with therapy outcome. PET identified those patients who responded less successfully to therapy.. CONCLUSION:. PET with ...http://uu.diva-portal.org/smash/record.jsf?pid=diva2:414225
't lymphocytes cytotoxic' Protocols and Video...
Video articles in JoVE about t lymphocytes cytotoxic include 'A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses', 'A Colorimetric Assay that Specifically Measures Granzyme B Proteolytic Activity: Hydrolysis of Boc-Ala-Ala-Asp-S-Bzl', 'Radial Mobility and Cytotoxic Function of Retroviral Replicating Vector Transduced, Non-adherent Alloresponsive T Lymphocytes', 'Murine Lymphocyte Labeling by 64Cu-Antibody Receptor Targeting for In Vivo Cell Trafficking by PET/CT', 'Phenotypic and Functional Analysis of Activated Regulatory T Cells Isolated from Chronic Lymphocytic Choriomeningitis Virus-infected Mice', 'Analysis of Simian Immunodeficiency Virus-specific CD8+ T-cells in Rhesus Macaques by Peptide-MHC-I Tetramer Staining', 'Induction of Invasive Transitional Cell Bladder ...https://www.jove.com/keyword/t+lymphocytes+cytotoxic
Gemcitabine Hydrochloride and Cisplatin With or Without Bevacizumab in Treating Patients With Advanced Urinary Tract Cancer -...
PRIMARY OBJECTIVES:. I. To determine if patients with advanced transitional cell carcinoma treated with bevacizumab, gemcitabine (gemcitabine hydrochloride) and cisplatin will have increased overall survival when compared to patients treated with gemcitabine, cisplatin, and placebo.. SECONDARY OBJECTIVES:. I. To compare the progression-free survival of these two regimens in patients with advanced transitional cell carcinoma.. II. To compare the proportion of patients who experience an objective response on each regimen.. III. To compare the grade 3 and greater toxicities in patients treated on the two regimens.. OUTLINE: Patients are randomized to 1 of 2 treatment arms.. ARM I: Patients receive gemcitabine hydrochloride intravenously (IV) over 30 minutes on days 1 and 8, cisplatin IV, and placebo IV over 30-90 minutes on day 1. Treatment repeats every 21 days for 6 courses ...https://clinicaltrials.gov/ct2/show/NCT00942331?term=topeka&recr=Open&rank=12
Gemcitabine Hydrochloride and Cisplatin With or Without Bevacizumab in Treating Patients With Advanced Urinary Tract Cancer -...
PRIMARY OBJECTIVES:. I. To determine if patients with advanced transitional cell carcinoma treated with bevacizumab, gemcitabine (gemcitabine hydrochloride) and cisplatin will have increased overall survival when compared to patients treated with gemcitabine, cisplatin, and placebo.. SECONDARY OBJECTIVES:. I. To compare the progression-free survival of these two regimens in patients with advanced transitional cell carcinoma.. II. To compare the proportion of patients who experience an objective response on each regimen.. III. To compare the grade 3 and greater toxicities in patients treated on the two regimens.. OUTLINE: Patients are randomized to 1 of 2 treatment arms.. ARM I: Patients receive gemcitabine hydrochloride intravenously (IV) over 30 minutes on days 1 and 8, cisplatin IV, and placebo IV over 30-90 minutes on day 1. Treatment repeats every 21 days for 6 courses ...https://clinicaltrials.gov/ct2/show/study/NCT00942331
Gemcitabine Hydrochloride and Cisplatin With or Without Bevacizumab in Treating Patients With Advanced Urinary Tract Cancer -...
PRIMARY OBJECTIVES:. I. To determine if patients with advanced transitional cell carcinoma treated with bevacizumab, gemcitabine (gemcitabine hydrochloride) and cisplatin will have increased overall survival when compared to patients treated with gemcitabine, cisplatin, and placebo.. SECONDARY OBJECTIVES:. I. To compare the progression-free survival of these two regimens in patients with advanced transitional cell carcinoma.. II. To compare the proportion of patients who experience an objective response on each regimen.. III. To compare the grade 3 and greater toxicities in patients treated on the two regimens.. OUTLINE: Patients are randomized to 1 of 2 treatment arms.. ARM I: Patients receive gemcitabine hydrochloride intravenously (IV) over 30 minutes on days 1 and 8, cisplatin IV, and placebo IV over 30-90 minutes on day 1. Treatment repeats every 21 days for 6 courses ...https://clinicaltrials.gov/ct2/show/study/NCT00942331?view=record
Transitional Cell Cancer (Pelvis and Ureter)
The kidneys are a "matched" pair of organs found on either side of your backbone. The kidneys of an adult are about 5 inches long and 3 inches wide and are shaped like a kidney bean. Inside each kidney are tiny tubules that clean your blood, taking out waste products and making urine. The urine made by the kidneys passes through the ureter into the bladder where it is held until it is passed from your body. The renal pelvis is the part of the kidney that collects urine and drains it to the ureters. The cells that line the renal pelvis and ureters are called transitional cells, and it is these cells that are affected in TCC. If you have a more common type of kidney cancer called renal cell cancer, see the patient information statement on renal cell cancer ...http://marystolfacancerfoundation.org/TransitionalCellCancerPelvisandUreter.html