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*  Metastatic spinal cord compression in prostate cancer : clinical and morphological studies
Background: Bone metastases occur in most patients with advanced hormone-refractory prostate cancer causing pain, pathologic fractures, and spinal cord compression. Few studies specifically address surgical treatment of metastatic spinal cord compression (MSCC) in prostate cancer. Criteria for identifying patients who may benefit from surgery are poorly defined. Most of the current knowledge regarding tumor biology in prostate cancer is based on studies of primary tumors or soft tissue metastases. The mechanisms regulating growth of bone metastases are not fully established.. Aims: a) to evaluate outcome after surgery for MSCC in prostate cancer and to identify prognostic factors for survival and functional recovery; b) to evaluate current practice for referral of prostate cancer patients with MSCC; c) to analyze expression of androgen ...
  http://umu.diva-portal.org/smash/record.jsf?pid=diva2:523874
*  Metastatic spinal cord compression - NICE Pathways
|div id='teaser' class='fragment teaser '||div class='p'|Everything NICE has said on detecting and managing metastatic spinal cord compression in adults with cancer in an interactive flowchart|/div||/div|
  http://pathways.nice.org.uk/pathways/metastatic-spinal-cord-compression
*  Excellent and durable response to radiotherapy in a rare case of spinal cord compression due to extra-medullary hematopoiesis...
Excellent and durable response to radiotherapy in a rare case of spinal cord compression due to extra-medullary hematopoiesis in β-thalassemia intermedia: case report and clinicoradiological correlation
  http://apm.amegroups.com/article/view/12773/13100
*  Excellent and durable response to radiotherapy in a rare case of spinal cord compression due to extra-medullary hematopoiesis...
Excellent and durable response to radiotherapy in a rare case of spinal cord compression due to extra-medullary hematopoiesis in β-thalassemia intermedia: case report and clinicoradiological correlation
  http://apm.amegroups.com/article/view/12773/14709
*  Survival analysis of malignant epidural spinal cord compression after palliative radiotherapy using Tokuhashi scoring system...
Survival analysis of malignant epidural spinal cord compression after palliative radiotherapy using Tokuhashi scoring system and the impact of systemic therapy
  http://apm.amegroups.com/article/view/16291
*  Erythropoietin Spinal Cord Compression Randomized Trial - Full Text View - ClinicalTrials.gov
For patients with malignant spinal cord compression (MSCC) who are paraparetic or paraplegic before initiating treatment, the current treatment options provide a meager to poor chance of neurologic recovery and the prognosis is guarded. Improving the chance of ambulation after treatment for MSCC may dramatically improve patients' quality of life, decrease days spent in hospital and improve survival. Steroids appear to prevent neurologic damage from MSCC and increasing doses appear to have an increasingly protective effect, however, higher doses are limited by an increasing incidence of serious toxicity.. Recombinant human erythropoetin has been shown to improve quality of life in patients with anemia of chronic disease and animal models suggest that r-HuEPO may have a neuroprotective effect. Human studies have demonstrated increased CSF concentrations of r-HuEPO after intravenous administration, including patients with ...
  https://clinicaltrials.gov/ct2/show/NCT00220675?cond=%22Charcot-Marie-Tooth+Disease%22&rank=13
*  Erythropoietin Spinal Cord Compression Randomized Trial - Full Text View - ClinicalTrials.gov
For patients with malignant spinal cord compression (MSCC) who are paraparetic or paraplegic before initiating treatment, the current treatment options provide a meager to poor chance of neurologic recovery and the prognosis is guarded. Improving the chance of ambulation after treatment for MSCC may dramatically improve patients' quality of life, decrease days spent in hospital and improve survival. Steroids appear to prevent neurologic damage from MSCC and increasing doses appear to have an increasingly protective effect, however, higher doses are limited by an increasing incidence of serious toxicity.. Recombinant human erythropoetin has been shown to improve quality of life in patients with anemia of chronic disease and animal models suggest that r-HuEPO may have a neuroprotective effect. Human studies have demonstrated increased CSF concentrations of r-HuEPO after intravenous administration, including patients with ...
  https://clinicaltrials.gov/ct2/show/NCT00220675?term=%22Charcot-Marie-Tooth+disease%22+%5BDISEASE%5D+OR+NCT00004568+%5BID-NUMBER%5D&rank=16
*  Compression médullaire / Spinal cord compression - drdangvu
Dexamethasone (a potent glucocorticoid) in doses of 16 mg/day may reduce edema around the lesion and protect the cord from injury. It may be given orally or intravenously for this indication.. Surgery is indicated in localised compression as long as there is some hope of regaining function. It is also occasionally indicated in patients with little hope of regaining function but with uncontrolled pain. Postoperative radiation is delivered within 2-3 weeks of surgical decompression. Emergency radiation therapy (usually 20 Gray in 5 fractions or 30Gy in 10 fractions) is the mainstay of treatment for malignant spinal cord compression. It is very effective as pain control and local disease control. Some tumors are highly sensitive to chemotherapy (e.g. lymphomas, small-cell lung cancer) and may be treated with chemotherapy alone.. Once complete ...
  https://sites.google.com/site/drdangvu/neurologie/compression-medullaire-spinal-cord-compression
*  Surgical Spinal Decompression of Metastatic Spinal Cord Compression, Minimal Access Versus Open Surgery
The investigators wish to evaluate the effect of minimal access spinal surgery compared to traditional open surgery spinal surgery in patients with meta
  http://www.knowcancer.com/cancer-trials/NCT01865942/
*  Early intervention results in lower mortality in patients with cancer hospitalized for metastatic spinal cord compression | JIM
Thank you for your interest in spreading the word on JIM.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.. ...
  http://jim.bmj.com/content/early/2017/01/30/jim-2016-000334.e-letters
*  Malignant spinal cord compression (MSCC) - diagnosis and treatment - Information and support - Macmillan Cancer Support
If you or someone close to you has been diagnosed with cancer, you're not alone. Find out what to expect, get information, practical advice and support, hear from experts and read about other people's experiences.
  http://www.macmillan.org.uk/information-and-support/bone-cancer-secondary/coping/side-effects-and-symptoms/other-side-effects/malignant-spinal-cord-compression-diagnosis-treatment.html
*  Top Metastatic Spinal Cord Cancer Hospitals in Thane | Credihealth
View details of top metastatic spinal cord cancer hospitals in Thane. Get guidance from medical experts to select best metastatic spinal cord cancer hospital in Thane
  https://www.credihealth.com/hospitals/thane/metastatic-spinal-cord-cancer
*  December 2017 - Home FurEver
Leif's diagnosis from an MRI shows dorsal to dorsal lateral bilaterally smoothly marginated regions of moderate to severe spinal cord compression at level T3-T6 causing dorsal and lateral to circumferential spinal cord compression. These findings are most consistent with spinal cord compression secondary to bony spinal malformation (hemivertebra).. We cannot afford this surgery due to the number vet bills incurred over this past year for veterinary care of our dogs and puppies. Home FurEver is in need of funds not only for Leif's surgery, but to pay our outstanding vet bills and the continued emergency care for all of the dogs and puppies in our care.. Continue reading "Happy Holidays and Urgent Plea for Donations for Leif" ...
  http://homefurever.com/2017/12/
*  Cord compression secondary to intradural ossification. - Oxford Neuroscience
The authors describe two patients presenting with a previous history of spinal trauma and a several-year history of sensory changes secondary to spinal cord compression. Both patients underwent laminectomy and spinal decompression operations. In both cases intradural bone causing neural compression was removed at operation. Potential mechanisms to explain intradural ossification and the relevant literature are reviewed.
  https://www.neuroscience.ox.ac.uk/publications/140610
*  Spinal Cord Compression: Evaluation
Another name for Spinal Cord Compression is Epidural Compression Syndrome. The evaluation of epidural compression syndrome begins with a history and physical ...
  http://www.freemd.com/spinal-cord-compression/evaluation.htm
*  Spinal Cord Compression Spinal Stenosis Market Registering A CAGR of ~ 11.5 % Expected by 2023 « MarketersMedia - Press...
The Global Spinal Cord Compression Spinal Stenosis Market report segmented on the basis of indications, diagnosis and treatment, implants and end users. Based on indications, the market has been segmented as foraminal stenosis and others.
  https://marketersmedia.com/spinal-cord-compression-spinal-stenosis-market-registering-a-cagr-of-11-5-expected-by-2023/242393
*  Surgery for Triple-Level Spinal Cord Compression | TheHorse.com
Spinal cord compression in the neck, more technically known as cervical vertebral stenotic myelopathy or CVSM, can cause notable incoordination and affects about 2% of racing Thoroughbreds. Probably the most well-known horse affected by CVSM was
  http://www.thehorse.com/articles/20855/surgery-for-triple-level-spinal-cord-compression
*  Paraesthesia due to spinal cord compression - Online Doctor Chats
Online Doctor Chat - Paraesthesia due to spinal cord compression, Ask a Doctor about when and why Magnetic resonance imaging is advised, Online doctor patient chat conversation by Dr. Raju A.T
  http://www.healthcaremagic.com/doctorchatlogs/Paraesthesia-due-to-spinal-cord-compression/51130
*  Neuroblastoma with spinal cord compression: is there an emergency treatment of choice? - Zurich Open Repository and Archive
Poretti, Andrea; Grotzer, Michael A (2012). Neuroblastoma with spinal cord compression: is there an emergency treatment of choice? Developmental Medicine and Child Neurology, 54(4):297-298. ...
  http://www.zora.uzh.ch/id/eprint/69996/
*  metastatic epidural spinal cord compression | healthPlexus.net
Abstract: Vertebral metastatic disease afflicts a significant proportion of cancer patients, most commonly those with breast and lung disease. Symptoms can include tumor-related pain, neurological deficit from spinal cord or nerve compression and pathological fracture with mechanical instability. Appropriate workup includes identifying the primary disease, defining the extent of spinal and extra-spinal pathology and classifying spinal stability based on the pattern of osseous involvement. Specific therapy for the vertebral metastatic disease can include pharmacologic therapy to deliver analgesia, steroids, bisphosphonate, anti-neoplastic therapy, radiation therapy as either primary or adjuvant therapy and surgical intervention for mechanical or neurologic instability ...
  https://www.healthplexus.net/keyword/metastatic-epidural-spinal-cord-compression
*  Single Session Spine Stereotactic Radiosurgery in Metastatic Epidural Spinal Cord Compression - Full Text View - ClinicalTrials...
Patients who have previously received maximum cord tolerance of 45 Gy in 5 weeks conventional fractionation or similar biologically effective dose (BED) to the area of the spine to be treated. Below are the normalized BED at 2 Gy per fraction with alpha/beta=2 for spinal cord in commonly used fractionation schemes in previously irradiated patients. Conventional Radiotherapy (Normalized Biologically Effective Dose) 20 Gy in 5 fractions(30 Gy 2/2), 30 Gy in 10 fractions(37.5 Gy 2/2), 37.5 Gy in 15 fractions(42 Gy 2/2), 40 Gy in 20 fractions(40 Gy 2/2), 45 Gy in 25 fractions(43 Gy 2/2), 50 Gy in 25 fractions(50 Gy 2/2) following equation: nBED is calculated by dividing BED by (1 + d/a/b), where d is 2 Gy and for spinal cord late effect a/b is 2, and we describe the units as Gy 2/2 (i.e., Gy 2/2 = 2-Gy equivalent with a/b = 2 ...
  https://clinicaltrials.gov/ct2/show/NCT01256554
*  Epidural spinal cord compression: a single institution's retrospective experience.
PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.
  http://pubmedcentralcanada.ca/pmcc/articles/PMC1920751/
*  PET predicts outcomes for patients with cervical spinal cord compression - Metabolic activity in spine indicates optimal time...
For patients with degenerative cervical myelopathy, imaging with 18F-FDG positron emission tomography (PET) could act as a marker for a potentially reversible phase of the disease in which substantial clinical improvement can be achieved ...
  https://www.painweek.org/news_posts/pet-predicts-outcomes-for-patients-with-cervical-spinal-cord-compression-metabolic-activity-in-spine-indicates-optimal-time-for-surgery.html