Frontiers | Natural Mosquito-Pathogen Hybrid IgG4 Antibodies in Vector-Borne Diseases: A Hypothesis | Immunology
During transmission of most vector-borne diseases, the pathogen is delivered to the vertebrate host along with the arthropod ... particularly during immune responses to vector-borne diseases such as malaria, filariasis or dengue virus infection. Here, we ... particularly during immune responses to vector-borne diseases such as malaria, filariasis or dengue virus infection. Here, we ... there is very little ongoing research or information available regarding IgG4 bi-specificity with regards to infectious disease ...https://www.frontiersin.org/articles/10.3389/fimmu.2016.00380/full
Leishmania major - Wikipedia
Leishmania major is a species of parasites found in the genus Leishmania, and is associated with the disease zoonotic cutaneous ... ISBN 0-85199-436-9. "Ceneters for Disease Control and Prevention: Update: Cutaneous leishmaniasis in U.S military personnel- ... Though a vaccine does not yet exist that can prevent cutaneous leishmaniasis, it is speculated that one will be developed in ... L. major and its cousin, L. tropica, are recognized as causing the majority of cases of cutaneous leishmaniasis across the ...https://en.wikipedia.org/wiki/Leishmania_major
Robovirus - Wikipedia
The resulting disease, cutaneous leishmaniasis, causes large skin lesions on the face, arms, and legs. Rodent populations are ... Lassa virus from the Arenaviridae family causes Lassa Hemorrhagic fever and is also a robovirus transmitted by the rodent genus ... "Leishmaniasis" World Health Organization. Website: http://www.who.int/leishmaniasis/cutaneous_leishmaniasis/en/ Human Health in ... "Rodents"., CDC-Centers for Disease Control and Prevention. Page last reviewed 2010 July 29. Content SourceL Centers for Disease ...https://en.wikipedia.org/wiki/Robovirus
Comparative study on the nocturnal activity of phlebotomine sand flies in a highland and lowland foci of visceral leishmaniasis...
Leishmania donovani, the causative agent of visceral leishmaniasis (VL), is most probably vectored by Phlebotomus orientalis in ... The diseases manifest from self-healing cutaneous leishmaniasis (CL) to life-threatening visceral leishmaniasis (VL) . In ... Leishmaniases are a group of diseases caused by protozoan parasites of the genus Leishmania. ... gomezi (Diptera: Psychodidae), vectors of cutaneous leishmaniasis in north central Venezuela. J Med Entomol. 1997;34:110-5.View ...https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-017-2339-6
Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases
Leishmania genus encloses protozoan species that cause visceral, cutaneous, and mucocutaneous leishmaniasis in humans. The ... J. B. le Pecq, "Dexosomes as a therapeutic cancer vaccine: from bench to bedside," Blood Cells, Molecules, and Diseases, vol. ... B. J. C. Quah and H. C. O'Neill, "The immunogenicity of dendritic cell-derived exosomes," Blood Cells, Molecules, and Diseases ... J. R. Coura, "Chagas disease: control, elimination and eradication. Is it possible?" Memorias do Instituto Oswaldo Cruz, vol. ...https://www.hindawi.com/journals/jir/2015/832057/
Promastigote Existence in Infected Lesions of Cutaneous Leishmaniasis | OMICS International
Leishmaniasis is an endemic parasitic disease in 88 countries. It is widely distributed throughout the world, caused by vector- ... Leishmaniasis. Disease information. TDR diseases.. *le Fichoux Y, Quaranta JF, Aufeuvre JP, Lelievre A, Marty P, et al. (1999) ... Leishmaniasis is caused by vector-borne, obligate, intracellular hemoflagellates of the genus leishmania. The various species ... Hepburn N (2006) Cutaneous leishmaniasis. Clin Exp Dermatol 25: 363-3705.. *Nakkash-Chmaisse H, Makki R, Nahhas G, Knio K, ...https://www.omicsonline.org/open-access/promastigote-existence-in-infected-lesions-of-cutaneous-leishmaniasis-2329-9126.1000183.php?aid=31531
Protocols and Video Articles Authored by Noah Craft (Translated to Hebrew)
Nov-Dec, 2009 , Pubmed ID: 19889134 Leishmaniasis is a cluster of diseases caused by protozoa in the genus Leishmania. There ... review focuses on strategies for development of a vaccine against cutaneous leishmaniasis as a representative parasitic disease ... Journal of Global Infectious Diseases. Sep, 2010 , Pubmed ID: 20927287 The Leishmaniases are a group of diseases transmitted to ... The present review focuses on the diagnosis and treatment of cutaneous and mucocutaneous leishmaniasis. Characteristics of both ...https://www.jove.com/author/Noah_Craft?language=Hebrew
New World leishmaniasis from Spain | Postgraduate Medical Journal
... cutaneous, or mucocutaneous disease.1 Imported leishmania infection is on the increase as a result of increased travel to ... Infection by protozoa haemoflagates of the genus leishmania can cause a wide range of clinical syndromes which are grouped ... The same is also true of the protozoal infection leishmaniasis. Involvement of the nose in this disease is extremely rare ... forms of this disease. Southern Spain is a very common British tourist destination. The risk of developing leishmaniasis is low ...http://pmj.bmj.com/content/78/926/757
Bacterial diversity of the American sand fly Lutzomyia intermedia using high-throughput metagenomic sequencing | Parasites &...
... collectively known as leishmaniasis, in humans worldwide. American cutaneous leishmaniasis is a neglected disease transmitted ... while only one family and two genera were identified as Gram-positive. The genera Ochrobactrum, Bradyrhizobium and Pseudomonas ... intermedia female sand flies are distinct under specific physiological conditions and consist of 15 bacterial genera. The ... Sequence identification revealed two phyla (Proteobacteria and Actinobacteria), 11 families and 15 genera; 87 % of the bacteria ...https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-016-1767-z
Antileishmanial and Trypanocidal Activities of Extracts and Aporphine Alkaloids Isolated from Monodora Genus (Annonaceae) |...
Leishmaniasis and trypanosomiasis are protozoan diseases caused respectively by the kinetoplastid protozoan Leishmania ... There are three main forms of the disease: Cutaneous leishmaniasis which is the most common form of leishmaniasis and causes ... Leishmaniasis and trypanosomiasis are separate groups of arthropod-borne diseases of humans and other animals caused by ... Both genera belong to the Trypanosomatidae family of the order Kinetoplastida . These kinetoplastid diseases also referred ...https://www.omicsonline.org/open-access/antileishmanial-and-trypanocidal-activities-of-extracts-and-aporphinealkaloids-isolated-from-monodora-genus-annonaceae-2472-0992-1000136.php?aid=92067
Leishmania | Adult and Adolescent Opportunistic Infection | AIDSinfo
... leishmaniasis, disseminated cutaneous leishmaniasis, diffuse cutaneous leishmaniasis (an anergic form), and post-kala-azar ... In endemic areas, leishmaniasis is usually spread by infected sand flies of the genera Phlebotomus and Lutzomyia.2 However, in ... Leishmaniasis. In: Guerrant RL, Walker DH, Weller PF, eds. Tropical infectious diseases: principles, pathogens and practice. ... Recommendations for Treating Visceral and Cutaneous Leishmaniasis Treating Visceral Leishmaniasis. Preferred Therapy:. * ...https://aidsinfo.nih.gov/guidelines/html/4/adult-and-adolescent-oi-prevention-and-treatment-guidelines/350/leishmania
Molecules | Free Full-Text | Leishmanicidal Evaluation of Tetrahydroprotoberberine and Spirocyclic Erythrina-Alkaloids | HTML
Traditional medicines to treat leishmaniasis have serious side effects, as well as significant parasite resistance problems. In ... Leishmaniasis is one of the World's most problematic diseases in developing countries. ... This disease is caused by protozoa belonging to the Leishmania genus, and can present a broad spectrum of symptoms such as ... David, C.V.; Craft, N. Cutaneous and mucocutaneous leishmaniasis. Dermatol. Ther. 2009, 22, 491-502. [Google Scholar] [CrossRef ...http://www.mdpi.com/1420-3049/19/5/5692/htm
Innate Immune Activation and Subversion of Mammalian Functions by Leishmania Lipophosphoglycan
... as well as studies on disease vectors. Articles highlighting social and economic issues around the impact of parasites are also ... Articles covering host-parasite relationships and parasitic diseases will be considered, ... Leishmaniasis is caused by infection with protozoan parasites of the Trypanosomatid genus Leishmania. The disease is endemic in ... In humans, several disease manifestations have been observed, ranging from self-healing cutaneous lesions to progressive and ...https://www.hindawi.com/journals/jpr/2012/165126/
Cutaneous financial definition of cutaneous
What is cutaneous? Meaning of cutaneous as a finance term. What does cutaneous mean in finance? ... Definition of cutaneous in the Financial Dictionary - by Free online English dictionary and encyclopedia. ... Cutaneous leishmaniasis is an infection caused by a protozoan of the genus Leishmania and is transmitted by sandfly bites (3-7 ... The term leishmaniasis encompasses cutaneous and visceral anthroponotic and zoonotic diseases caused by the vector-borne ...http://financial-dictionary.thefreedictionary.com/cutaneous
The Immunotherapeutic Role of Regulatory T Cells in Leishmania (Viannia) panamensis Infection | The Journal of Immunology
... are the causative agents of leishmaniasis, which manifests as a wide spectrum of clinical diseases, including cutaneous, ... and the immunological mechanisms regulating infection and disease vary across the genus (5, 71, 72). In the case of L. major, ... Immunopathogenesis of non-healing American cutaneous leishmaniasis and progressive visceral leishmaniasis. Semin. Immunopathol. ... Genetic susceptibility to infectious disease: lessons from mouse models of leishmaniasis. Nat. Rev. Genet. 7: 294-305. ...http://www.jimmunol.org/content/193/6/2961
Immune response to leishmania: paradox rather than paradigm - Tripathi - 2007 - Pathogens and Disease - Wiley Online Library
The leishmaniases are a group of diseases caused by protozoan parasites of the genus Leishmania. Various Leishmania species can ... 1998) Immunologic determinants of disease evolution in localized cutaneous leishmaniasis due to Leishmania major. J Infect Dis ... Comparative immune study on cutaneous leishmaniasis patients with single and multiple sores, Journal of Parasitic Diseases, ... Jones DE, Merle Elloso M & Scott P (1998) Host susceptibility factors to cutaneous leishmaniasis. Front Bios 3: d1171-d1180. * ...http://onlinelibrary.wiley.com/doi/10.1111/j.1574-695X.2007.00311.x/full
cutaneous leishmaniasis (wet form). humans, rodents. Africa, Asia L. tropica. cutaneous leishmaniasis (dry form) humans, hyrax ... The two most important genera are Trypanosoma and Leishmania, the members of which are responsible for numerous diseases of ... Main forms are cutaneous leishmaniasis, which may be mutilating and disfiguring and visceral leishmaniasis, which is systemic ... visceral leishmaniasis (mostly). humans, dogs. Africa, Europe, South America. Phytomonas spp. hartrot disease. coconut, oil ...http://tolweb.org/Trypanosomatida
Combination and monotherapy of Leishmania major infection in BALB/c mice using plant extracts and herbicides. - Free Online...
Journal of Vector Borne Diseases'; Health, general Biological products Health aspects Herbicides Infection Care and treatment ... Diagnosis Materia medica, Vegetable Medical research Medicine, Experimental Parasitic diseases Plant extracts ... This phase of murine cutaneous leishmaniasis caused by L. major corresponds to the end of the acute phase of the Disease (27) ... It is caused by the protozoan parasite of the genus Leishmania and transmitted to the mammalian host by the bite of the ...https://www.thefreelibrary.com/Combination+and+monotherapy+of+Leishmania+major+infection+in+BALB%2Fc+...-a0309727733
Drug resistance in leishmaniasis - LSHTM Research Online | London School of Hygiene and Tropical Medicine
Leishmaniasis is a complex disease, with visceral and cutaneous manifestations, and is caused by over 15 different species of ... the protozoan parasite genus Leishmania. There are significant differences in the sensitivity of these species both to the ... Although this class of drugs has been used for over 60 years for leishmaniasis treatment, it is only in the past 2 years that ... Croft, SL; Sundar, S; Fairlamb, AH; (2006) Drug resistance in leishmaniasis. Clinical microbiology reviews, 19 (1). 111-+. ISSN ...http://researchonline.lshtm.ac.uk/12087/
Th1, Th2 Serum Cytokines and Spleen White Pulp Changes Against Preliminary L. Major Vaccine Injection and Challenge With Live L...
Human Leishmaniasis is distributed worldwide and is mainly in the tropics and subtropics, with a prevalence of 12 million cases ... and 1.5 million cases of cutaneous Leishmaniasis (CL) . Leishmaniasis denotes the human disease caused by any species in the ... protozoan parasite genus Leishmania. The parasites exist as flagellated extracellular promastigotes in their vectors, ... The disease in human can be divided into cutaneous, visceral, and mucosal syndromes. The aim of this study was to conduct ...https://www.omicsonline.org/open-access/th-th-serum-cytokines-and-spleen-white-pulp-changes-against-preliminary-l-major-vaccine-2155-9899-1000281.php?aid=38182
Laboratory of Cellular Immunology | Hellenic Pasteur Institute
Parasitic protozoa of the genus Leishmania cause a broad spectrum of diseases in humans from localized cutaneous lesions, ... In all forms of the disease, healing or recovery of leishmaniasis has been depended on specific Th1 cells. Inevitably, due to ... The development of PCR assay for the detection of cryptic leishmaniasis and its application to the study of the disease in ... mucosal infections of varying severity, or subclinical to acute visceral disease. Leishmaniasis are spanning throughout ...http://www.pasteur.gr/?page_id=836&lang=en
ORBi: Browsing ORBi
in BMC Infectious Diseases (2017), 17. Background: Leishmaniasis is a protozoan disease caused by parasites of the genus ... The disease can present in three ways: cutaneous, mucocutaneous, or visceral leishmaniasis, which rarely occur together or ... Background: Leishmaniasis is a protozoan disease caused by parasites of the genus Leishmania, transmitted to humans by ... Recurrence of visceral and muco-cutaneous leishmaniasis in a patient under immunosuppressive therapy. DARCIS, Gilles ; Van der ...http://orbi.ulg.ac.be/browse?type=author&value=MOUTSCHEN,%20Michel%20p001472
Pharmacological Assessment Defines Leishmania donovani Casein Kinase 1 as a Drug Target and Reveals Important Functions in...
Leishmaniasis is an important human disease caused by protozoan parasites of the genus Leishmania. This parasite has two ... There are several types of the disease, cutaneous, mucocutaneous, and visceral leishmaniasis, with the last type being the most ... suggesting that D4476 has an impact on the causative agents of cutaneous, mucocutaneous, and visceral leishmaniasis. IC261 had ... Leishmaniasis: complexity at the host-pathogen interface. Nat. Rev. Microbiol. 9:604-615. doi:10.1038/nrmicro2608. ...https://aac.asm.org/content/58/3/1501
Optimized CRISPR-Cas9 Genome Editing for Leishmania and Its Use To Target a Multigene Family, Induce Chromosomal Translocation,...
Leishmaniasis is a vector-borne disease caused by the protozoan parasite species of the genus Leishmania. Depending on the ... Leishmania infection can cause mild self-healing cutaneous leishmaniasis (CL), disfiguring mucocutaneous leishmaniasis (MCL), ... den Boer M, WHO Leishmaniasis Control Team. . 2012. Leishmaniasis worldwide and global estimates of its incidence. PLoS One 7: ... or fatal visceral leishmaniasis (VL), which is the second-deadliest parasitic disease after malaria (1, 2). Approximately 1 ...https://msphere.asm.org/content/2/1/e00340-16
DMOZ - Health: Conditions and Diseases: Infectious Diseases: Parasitic: Leishmaniasis
There are four major clinical types of this infection: cutaneous, diffuse cutaneous, mucocutaneous, and visceral. ... A disease caused by any of a number of species of protozoa in the genus Leishmania. ... A disease caused by any of a number of species of protozoa in the genus Leishmania. There are four major clinical types of this ... eMedicine: Leishmaniasis Provides an overview of this zoonotic infection caused by protozoa that belong to the genus Leishmania ...http://dmoztools.net/Health/Conditions_and_Diseases/Infectious_Diseases/Parasitic/Leishmaniasis/