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*  Patent US6953468 - Occluding vasculature of a patient using embolic coil with improved platelet ... - Google Patents
... the stagnation of blood that is obtained prevents the blood flow from rupturing the aneurysm. However, such stagnation forms a ... may be straight or may take the form of various configurations, including the form of a helix, a random shape configuration, or ... The embolic coils act to reduce the blood flow inside of the aneurysm. Typically the embolic coils provide a mechanical ... In the model, aneurysms treated with textured coils were compared to aneurysms treated with non-textured coils. The textured ...
  http://www.google.com.au/patents/US6953468
*  Brain aneurysm | definition of brain aneurysm by Medical dictionary
... brain aneurysm explanation free. What is brain aneurysm? Meaning of brain aneurysm medical term. What does brain aneurysm mean? ... Looking for online definition of brain aneurysm in the Medical Dictionary? ... In this case, the wall of the blood vessel is ruptured and blood escapes into surrounding tissues and forms a clot. Because of ... In false aneurysms, blood escapes between tunica layers and they separate. If the separation continues, a clot may form, ...
  https://medical-dictionary.thefreedictionary.com/brain+aneurysm
*  Lung aneurysm | definition of lung aneurysm by Medical dictionary
... lung aneurysm explanation free. What is lung aneurysm? Meaning of lung aneurysm medical term. What does lung aneurysm mean? ... Looking for online definition of lung aneurysm in the Medical Dictionary? ... In this case, the wall of the blood vessel is ruptured and blood escapes into surrounding tissues and forms a clot. Because of ... Small aneurysms may produce no sound at all. An aneurysm may rupture, causing hemorrhage, or thrombi may form in the dilation ...
  http://medical-dictionary.thefreedictionary.com/lung+aneurysm
*  US20050267407A1 - Multi-function catheter and use thereof - Google Patents
There may be a third lumen for bypassing a biological fluid such as blood while the catheter is being used. The method of using ... Although aneurysms can occur in any type of the body's blood vessels, they almost always form in an artery. A ruptured aneurysm ... Method for forming a stent in situ US6039757A (en) * 1997-03-12. 2000-03-21. Cardiosynopsis, Inc.. In situ formed fenestrated ... The connective tissue excluded the aneurysm from arterial blood flow. An aneurysm occluded from blood circulation may have a ...
  https://patents.google.com/patent/US20050267407A1/en
*  Aneurisms | definition of Aneurisms by Medical dictionary
aneurysm. also aneurism. (ăn′yə-rĭz′əm). n.. An abnormal, blood-filled sac formed by dilation of the wall of a blood vessel or ... Small aneurysms may produce no sound at all. An aneurysm may rupture, causing hemorrhage, or thrombi may form in the dilation ... See Abdominal aortic aneurysm, Aortic aneurysm, Berry aneurysm, Cerebral aneurysm, Mycotic aneurysm, Ruptured aortic aneurysm. ... mycotic aneurysm. Aneurysm due to bacterial infection. racemose aneurysm. Cirsoid aneurysm.. sacculated aneurysm. Aneurysm in ...
  https://medical-dictionary.thefreedictionary.com/Aneurisms
*  High Blood Pressure Symptoms You Can Reverse Naturally - Dr. Axe
The good news is there are ways to naturally reverse high blood pressure symptoms. ... High blood pressure affects a very large part of the population. ... forming an aneurysm. If an aneurysm ruptures, it can be life- ... Available in powder form, consumption of cocoa increases your intake of flavonols, which help lower blood pressure and improve ... High Blood Pressure vs. Low Blood Pressure. Risk of both low blood pressure and high blood pressure normally increases with age ...
  https://draxe.com/high-blood-pressure-symptoms/?utm_source=newsletter&utm_medium=email&utm_campaign=newsletter
*  Patent US6270516 - Repair apparatus for use in surgical procedures - Google Patents
The housing further includes at least one lumen formed in one of the plurality layers. The repair apparatus according to the ... The apparatus includes a housing, and at least one of a penetration apparatus for use in forming a treatment specific hole in a ... resulting in loss of blood through the rupture and death.. Aortic aneurysms are the most common form of arterial aneurysm and ... Left untreated, the aneurysm may rupture, resulting in rapid, and usually fatal, hemorrhaging. Typically, a surgical procedure ...
  http://www.google.com/patents/US6270516?dq=4,395,600
*  Disease of the Aorta - PVD - cardiovascular-disease - Heart Healthy Women
Aortic disease is a form of peripheral artery disease that affects the aorta, the largest artery in the body. The aorta is ... In addition to the risk of rupture, aneurysms are also dangerous because they can cause blood clots to form, which may break ... Over time, the force of blood flowing through the aorta causes a weak spot to bulge out like a balloon, forming an aneurysm. ... When aortic aneurysms rupture, they are fatal as much as 90% of the time.1 Each year nearly 14,000 Americans die of aortic ...
  http://www.hearthealthywomen.org/index_option_com_content_view_article_id_703_Itemid_729.html
*  High Blood Pressure Deemed Worst Possible Condition for Brain | EmaxHealth
... high blood pressure) can have devastating health consequences if not treated, including increasing your chances of developing ... Hemorrhagic strokes and aneurysms are caused by ruptures in the blood vessels. The overstretching of the blood vessels due to ... rupture or leak and also by the forming of blood clots in the arteries leading to your brain, blocking blood flow. But, there ... These could build to form a blockage which could lead to heart attack or stroke. ...
  https://www.emaxhealth.com/1506/high-blood-pressure-deemed-worst-possible-condition-brain
*  US20090125100A1 - Intraluminal Bypass Prosthesis and Prosthesis Delivery and Deployment Kit - Google Patents
... forming an aneurysm. If left untreated, hemodynamic forces can cause the aneurysm to rupture, resulting in internal bleeding, ... A61F2/86-Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like ... The prosthesis relines the aorta and excludes blood flow to the aneurysm. ... shows a schematic view of the aorta 10 of a patient with an aneurysm 12 that has formed in the descending aorta 14 and the ...
  https://patents.google.com/patent/US20090125100
*  COPPER SOURCES and NUTRITION to treat, HERNIATED DISCS, ANEURYSMS, GRAY HAIR, EMPHYSEMA, and HEMORRHOIDS
... aneurysm, anemia, hemorrhoids, high cholesterol, emphysema, and maybe gray hair. Physiology and nutrition of copper are ... Gaining carbohydrate in the form of sucrose or fructose will more than triple the mortality from ruptures in the top of the ... Acute symptoms of copper poisoning by ingestion include vomiting, hematemesis (vomiting of blood), hypotension (low blood ... Unfortunately there may also be a positive correlation with one of the forms of schizophrenia. It is also possible to get ...
  http://members.tripod.com/~charles_W/copper3.html
*  Thick Blood Vessel Wall - Causes of Thickened Artery, Vein | Healthhype.com
... occurs when blood enters a tear in the wall of the aorta. It forms a blood-filled channel within the wall that can rupture ... Aneurysm. An aneurysm is the bulging of a portion of a blood vessel. It is an abnormal dilatation, like a balloon, and may ... affect an intact vessel wall (true aneurysm) or diseased wall (false aneurysm).It is not an actual thickening of the blood ... Thickening of a blood vessel may occur for a number of reasons. It is usually a result of changes within the vessel wall ...
  https://www.healthhype.com/thick-blood-vessel-wall-causes-of-thickened-artery-vein.html
*  Strokes: Ischemic and Hemorrhagic · Guardian Liberty Voice
... eventually rupture, and then bleed into the brain. An AVM is a group of abnormally formed blood vessels that can rupture at any ... Strokes happen when the blood supply to the brain is altered in some form, either not enough blood or too much blood on the ... Conditions that can cause the ruptures include trauma, hypertension, aneurysms and blood-thinning medications. ... Two types of weakened blood vessels cause hemorrhagic strokes, aneurysms and arteriovenous malformations (AVMs). An aneurysm ...
  http://guardianlv.com/2015/05/strokes-ischemic-and-hemorrhagic/
*  Canadian Task Force on Preventive Health Care | The CTFPHC Newsletter Issue 14
... forming an aneurysm. The aneurysm may grow and eventually rupture causing death from hemorrhage. It is estimated that each year ... An AAA results from a weakening in a section of the aortic wall in the abdomen which bulges due to pressure from blood flow, ... or complete the online form. ... Since an AAA is usually asymptomatic before rupture, screening ... Release of the CTFPHC's Abdominal Aortic Aneurysm (AAA) Guideline. Earlier this month, the CMAJ published the CTFPHC's ...
  https://canadiantaskforce.ca/the-ctfphc-newsletter-issue-14/
*  Inflammatory aortic aneurysm - Wikipedia
blood clots may form at the site and dislodge, increasing the chance of stroke Increase in the size of the aneurysm, causing it ... Aneurysm may also rupture. It is fragile and may burst under stress. The rupture of an aortic aneurysm is a catastrophic, life- ... Cigarette smoking and other forms of tobacco use appear to increase your risk of aortic aneurysms. In addition to the damaging ... However, aneurysms increase the risk for: Atherosclerotic plaques to form at the site of the aneurysm, which causes further ...
  https://en.wikipedia.org/wiki/Inflammatory_aortic_aneurysm
*  Takayasu's arteritis - Wikipedia
As with all aneurysms, the possibility of rupture and vascular bleeding is existent and requires monitoring. In view of the ... This inflammation leads to arterial stenosis, thrombosis, and aneurysms. There is irregular fibrosis of the blood vessels due ... Takayasu's arteritis is similar to other forms of vasculitis, including giant cell arteritis which typically affects older ... is a form of large vessel granulomatous vasculitis with massive intimal fibrosis and vascular narrowing, most commonly ...
  https://en.wikipedia.org/wiki/Takayasu's_arteritis
*  Ventricular aneurysm - Wikipedia
Also, blood clots may form on the inside of ventricular aneurysms, and form embolisms. If such a clot escapes from the aneurysm ... Blood thinning agents may be given to help reduce the likelihood of blood thickening and clots forming, along with the use of ... Ventricular aneurysms can be fatal. They are usually non-rupturing because they are lined by scar tissue. A left ventricular ... The word aneurysm refers to a bulge or 'pocketing' of the wall or lining of a vessel commonly occurring in the blood vessels at ...
  https://en.wikipedia.org/wiki/Ventricular_aneurysm
*  Traumatic aortic rupture - Wikipedia
... sometimes forming a false aneurysm. A sub-intimal hemorrhage is the least serious type. The condition is difficult to detect ... A common symptom is unusually high blood pressure in the upper body and very low blood pressure in lower limbs. Another symptom ... When the aorta is partially torn, it may form a "pseudoaneurysm". In patients who do live long enough to be seen in a hospital ... Aortic rupture can also be caused by non-traumatic mechanisms, particularly abdominal aortic aneurysm rupture. The injury is ...
  https://en.wikipedia.org/wiki/Traumatic_aortic_rupture
*  Aortic aneurysm - Wikipedia
... or descending aneurysms. Abdominal aortic aneurysms, "AAA" or "Triple A," the most common form of aortic aneurysm, involve that ... The risk of rupture of an AAA is related to its diameter; once the aneurysm reaches about 5 cm, the yearly risk of rupture may ... Rarely, clotted blood which lines most aortic aneurysms can break off and result in an embolus. Aneurysms can be found on ... artery in mice both reduced the size of aneurysms that had already grown and prevented abdominal aortic aneurysms from forming ...
  https://en.wikipedia.org/wiki/Aortic_aneurysm
*  Aorta - Wikipedia
The ventral aorta carries de-oxygenated blood from the heart to the gills; part of this vessel forms the ascending aorta in ... The smooth muscle of the great arteries and the population of cells that form the aorticopulmonary septum that separates the ... Aortic aneurysm - mycotic, bacterial (e.g. syphilis), senile, genetic, associated with valvular heart disease Aortic ... such as traumatic aortic rupture, most often thoracic and distal to the left subclavian artery and often quickly fatal ...
  https://en.wikipedia.org/wiki/Aorta
*  Hamartoma - Wikipedia
The great majority of them form in the connective tissue on the outside of the lungs, although about 10% form deep in the ... One general danger of hamartomas is that they may impinge into blood vessels, resulting in a risk of serious bleeding. Because ... They almost always arise from connective tissue and are generally formed of cartilage, connective tissue, and fat cells, ... and they are often associated with hematologic abnormalities and spontaneous rupture. Considered part of the PTEN hamartoma ...
  https://en.wikipedia.org/wiki/Hamartoma
*  Subarachnoid hemorrhage - Wikipedia
When the aneurysm has been located, platinum coils are deployed that cause a blood clot to form in the aneurysm, obliterating ... usually from a ruptured cerebral aneurysm. Risk factors for spontaneous cases included high blood pressure, smoking, family ... It usually happens in the setting of other forms of traumatic brain injury and has been linked with a poorer prognosis. It is ... more blood and larger aneurysm on the initial CT scan; location of an aneurysm in the posterior circulation; and higher age. ...
  https://en.wikipedia.org/wiki/Subarachnoid_hemorrhage
*  Angiomyolipoma - Wikipedia
A ruptured aneurysm in an angiomyolipoma leads to blood loss that must be stopped (though embolisation) and compensated for ( ... In patients with TSC, a longitudinal study found 80% will have some form of renal lesion by around 10 years of age. Of these, ... Older literature may classify them as hamartomas (benign tumours consisting of cells in their correct location but forming a ... An angiomyolipoma larger than 5 cm and those containing an aneurysm pose a significant risk of rupture, which is a medical ...
  https://en.wikipedia.org/wiki/Angiomyolipoma
*  Thrombin - Wikipedia
Blood from a ruptured cerebral aneurysm clots around a cerebral artery, releasing thrombin. This can induce an acute and ... Factor Xa with factor V as a cofactor leads to cleavage of the Gla and two Kringle domains (forming together a fragment called ... Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the clotting process. Thrombin in turn acts ... In the blood coagulation pathway, thrombin acts to convert factor XI to XIa, VIII to VIIIa, V to Va, fibrinogen to fibrin, and ...
  https://en.wikipedia.org/wiki/Thrombin
*  Familial Intracranial Aneurysm Study II - Full Text View - ClinicalTrials.gov
Intracranial aneurysms are 'blisters' which form within the arteries at the base of the brain. A rupture of an aneurysm may lead to subarachnoid hemorrhage (SAH). The mortality rates of patients suffering from a SAH is 40 to 44 percent , with many survivors enduring major disability. Most of the deaths from SAH are due to rapid and massive brain injury from the initial bleeding, which is not correctable by medical and surgical intervention. Thus, prevention of aneurysm formation is of paramount importance.. Scientific evidence suggests that a genetic component plays an important role in the development of intracranial aneurysms, however the specific genes have not been identified. The Familial Intracranial Aneurysm Study is a collaborative research effort of neurologists and neurosurgeons throughout the ...
  https://clinicaltrials.gov/ct2/show/study/NCT00071565
*  Risk-benefit analysis of the treatment of unruptured intracranial aneurysms
Objectives: To determine under what circumstances repair of unruptured intracranial aneurysms may be beneficial. Methods: A life expectancy analysis of patients with unruptured aneurysms with and without repair based on prospective data from the International Study of Unruptured Intracranial Aneurysms (ISUIA). Results: Life years are lost at all ages by repairing anterior circulation aneurysms under 7 mm in diameter in patients with no history of a subarachnoid haemorrhage from another aneurysm (incidental). For all other aneurysms the number of life years saved by repair is dependent on the patient's age at the time when repair is undertaken. Between 2 and 40 years are saved by repairing aneurysms in patients aged 20 years. ...
  http://connection.ebscohost.com/c/articles/16896901/risk-benefit-analysis-treatment-unruptured-intracranial-aneurysms
*  Abstract 14: Size Ratio can be a Strong Predictor for Future Rupture of the Unruptured Cerebral Aneurysms | Stroke
Introduction: Various factors have been nominated for the rupture of unruptured cerebral aneurysms including size, shape and specific locations of aneurysms. Size ratio, which is the quotient of maximum size of the aneurysm divided by the diameter of the adjacent parent artery, has also been nominated as a strong indicator to discriminate ruptured versus unruptured cerebral aneurysms. However, this has never been tested as a risk in the prospective cohort. In this paper, we have assimilated size ratio in cases of UCAS Japan using reported average parent arterial size and evaluated its value.. Methods: We used average main intracranial artery diameter reported in anatomical studies as follows: AComA: 1.5mm, MCA: 3.9mm, ICA: 4.3mm, PComA: 1.3mm, BA: 4.1mm and VA: 3.9mm. UCAS Japan cohort, which is a Japanese prospective cohort ...
  http://stroke.ahajournals.org/content/47/Suppl_1/A14
*  Intracranial aneurysm - Wikipedia
Intracranial aneurysm, also known as brain aneurysm, is a cerebrovascular disorder in which weakness in the wall of a cerebral artery or vein causes a localized dilation or ballooning of the blood vessel. Aneurysms in the posterior circulation (basilar artery, vertebral arteries and posterior communicating artery) have a higher risk of rupture. Basilar artery aneurysms represent only 3%-5% of all intracranial aneurysms but are the most common aneurysms in the posterior circulation. Cerebral aneurysms are classified both by size and shape. Small aneurysms have a diameter of less than 15 mm. Larger aneurysms include those classified as large (15 to 25 mm), giant (25 to 50 mm), and super-giant ...
  https://en.wikipedia.org/wiki/Intracranial_aneurysm
*  North Shore University Hospital's Brain Aneurysm Center Offers New Pipeline® Embolization Device to Treat Complex Brain...
The PED is a flexible, braided wire mesh tube which can be placed within the internal carotid artery in the brain, blocking off large or wide-necked aneurysms. The device can also reduce the likelihood that an aneurysm will rupture. "The Pipeline® Embolization Device offers neurointerventional surgeons a minimally invasive alternative to open surgery or placement of materials such as coils or a liquid embolic when treating carotid artery brain aneurysms," said Avi Setton, MD, chief of interventional neuroradiology at North Shore University Hospital. "While coiling can be effective for small brain aneurysms, it does not always work on larger ones. The PED device offers patients a better chance of long-lasting aneurysm occlusion and low complication rates.". In the endovascular procedure, the PED is threaded up through a catheter placed in a ...
  https://www.healthcanal.com/brain-nerves/22985-north-shore-university-hospitals-brain-aneurysm-center-offers-new-pipeline-embolization-device-to-treat-complex-brain-aneurysms.html
*  Flow Diverter Stent for Endovascular Treatment of Unruptured Saccular Wide-necked Intracranial Aneurysms - Full Text View -...
Unruptured saccular intracranial aneurysms larger than 7 mm can be treated with endovascular occlusion using detachable coils, with or without expendable stent assistance. A new endovascular technique has recently been developed, using flow diverter stents without associated coils. Clinical results already published are encouraging but have to be confirmed. Furthermore, these medical devices are expensive in comparison to the coiling strategy. The purpose of this study is to compare the clinical efficacy, safety, and cost-effectiveness of endovascular coiling and endovascular flow diversion for unrupted saccular intracranial aneurysms ...
  https://clinicaltrials.gov/ct2/show/NCT01811134?recr=Open&cond=%22Intracranial+Aneurysm%22&rank=5
*  Plus it
Unruptured intracranial aneurysms are common and occurred in approximately 1%-2% of the population, as reviewed by Vlak et al.19 Because most unruptured intracranial aneurysms are asymptomatic and are found incidentally, treatment should be considered after balancing the natural history of the aneurysm with the risk posed by the treatment. Prospective data for the natural history of unruptured intracranial aneurysms by the International Study of Unruptured Intracranial Aneurysms and UCAS Japan investigators showed that the annual rupture rate increased for aneurysms that were ≥7 mm. The presence of a daughter sac and a history of SAH increased the rupture rate.5,7 In the Japanese cohort, the annual rupture rates for paraclinoid ...
  http://www.ajnr.org/content/37/4/679
*  The Giant Intracranial Aneurysm Registry | ESMINT
ESMINT - Scientific evidence on giant intracranial aneurysms so far has been scarce and it is often difficult to properly advise patients. The Giant Intracranial Aneurysm Registry is an international registry of intracranial giant aneurysms. Its main goal is ...
  http://esmint.eu/research/giant-intracranial-aneurysm-registry
*  Abstract 3956: Outcomes of Patients Undergoing Endovascular Treatment for Mycotic Intracranial Aneurysms | Stroke
Background: Mycotic intracranial aneurysms are rare with primary treatment focusing on underlying infection to reduce the high mortality rates. Treating these aneurysms remains challenging and obliteration procedures without sacrificing the parent artery often fail due to the fusiform and fragile aneurysm wall.. Objective: To determine the outcomes associated with endovascular embolization in patients with mycotic intracranial aneurysms using a large nationally representative sample.. Methods: We determined the frequency of endovascular and surgical procedures performed in patients with mycotic intracranial aneurysms and associated in-hospital outcomes using data from the Nationwide Inpatient Survey (NIS) data files from 2002 to 2009. All the in-hospital outcomes were analyzed after ...
  http://stroke.ahajournals.org/content/43/Suppl_1/A3956
*  Risk of Rupture of an Intracranial Aneurysm Based on Patient Characteristics | Stroke
Methods-We performed a case-control study with 250 patients with an aneurysmal subarachnoid hemorrhage and 206 patients with an unruptured intracranial aneurysm. All patients with an aneurysmal subarachnoid hemorrhage and patients with a unruptured intracranial aneurysm were asked to fill in a structured questionnaire about their lifestyle and medical history. For patients with an unruptured intracranial aneurysm, we also collected data on the indication for imaging. With logistic regression analysis, we identified independent risk factors for aneurysmal rupture.. ...
  http://stroke.ahajournals.org/content/early/2013/03/21/STROKEAHA.111.000679
*  Brain Aneurysm Awareness | Sara Mason's Fundraiser
Brain Aneurysm Foundation Incorporated wrote - Revlon has challenged the Brain Aneurysm Foundation to raise as much money as possible in 6 weeks for our cause. It's on! We can win the Revlon Love is On Million Dollar Challenge by being the top fundraiser! That's 1,000,000 for the winner. Second place gets $100,000. Every dollar donated to our campaign goes toward fulfilling our mission - providing critical awareness, education, support and research funding to reduce the incidence of brain aneurysm ruptures. The catch? We need to raise the most money by October 26th! Show us the love! What better time than Brain Aneurysm Awareness Month to show survivors, families, caregivers and the medical community love by donating to our Brain Aneurysm Awareness Month campaign. The Brain Aneurysm Foundation ...
  https://www.crowdrise.com/thebrainaneurysmfoundation-revlon2016/fundraiser/saramason7
*  Treatment of Cranial Internal Carotid Artery Aneurysm With Willis Covered Stent and Coil Embolization - Full Text View -...
Endovascular treatment of intracranial aneurysms with detachable coils has been widely used since the introduction of GDCs in 1991 and has been proven to be effective in preventing rebleeding after aneurysmal rupture. The clinical and angiographic results of endovascular coil occlusion of intracranial aneurysms are positive, with an initial and final overall complete occlusion rate of 35.9%-76.8% and 38.3%- 87.8%. In the mid- and long-term, however, aneurysm recanalization may occur in as many as one-third of cases.. The natural history of aneurysm recurrence after coil treatment is often benign, but bleeding from incompletely coiled aneurysms is a well-documented threat, moreover, the degree of aneurysm occlusion after treatment was strongly associated with risk of ...
  https://clinicaltrials.gov/ct2/show/NCT01029938?recr=Open&cond=%22Intracranial+Aneurysm%22&rank=18
*  Treatment of Cranial Internal Carotid Artery Aneurysm With Willis Covered Stent and Coil Embolization - Tabular View -...
Endovascular treatment of intracranial aneurysms with detachable coils has been widely used since the introduction of GDCs in 1991 and has been proven to be effective in preventing rebleeding after aneurysmal rupture. The clinical and angiographic results of endovascular coil occlusion of intracranial aneurysms are positive, with an initial and final overall complete occlusion rate of 35.9%-76.8% and 38.3%- 87.8%. In the mid- and long-term, however, aneurysm recanalization may occur in as many as one-third of cases.. The natural history of aneurysm recurrence after coil treatment is often benign, but bleeding from incompletely coiled aneurysms is a well-documented threat, moreover, the degree of aneurysm occlusion after treatment was strongly associated with risk of ...
  https://clinicaltrials.gov/ct2/show/record/NCT01029938
*  Intraoperative microvascular Doppler in intracranial aneurysm surgery. | IRIS Università degli Studi di Padova
OBJECTIVE: The usefulness of intraoperative microvascular Doppler (IMD) in preventing an incorrect placement of the clip during intracranial aneurysm surgery is described. Such incorrect placement of the clip may cause new bleeding or ischemic accident as a consequence of incomplete exclusion of the aneurysm or stenosis/occlusion of the parent and/or adjacent arteries. METHODS: One hundred thirty patients, harboring 136 aneurysms, were operated on using IMD. IMD study was performed on the aneurysm and adjacent arterial vessels before and after the clip placement. Mechanical arterial spasm was treated by topical sodium nitroprusside (SNP) and its efficacy verified by IMD. RESULTS: In 55 aneurysms (42.3%), IMD was helpful in understanding the microvascular anatomy before clip placement. Complete exclusion ...
  https://www.research.unipd.it/handle/11577/153027
*  Stroke: Highlights of Selected Articles | Stroke
Patients with symptomatic intracranial aneurysms are frequently found to have additional aneurysms and may develop new aneurysms over time. LOTUS, long-term stability of coiled intracranial aneurysms, is a study in which MRA (3-D time of flight) was performed on patients in a large cohort with previously coiled aneurysms at 5 years follow-up. In 50 of 276 patients (18%), 75 additional aneurysms were found on follow-up MRA. The majority, 89%, of these additional aneurysms were unchanged, whereas only 5 had grown (from 1-3 mm) and only 2 were de novo (both 3 mm). The cumulative 5-year incidence of de novo aneurysm formation was 0.75%. The clinical implication of these findings from the MRA ...
  http://stroke.ahajournals.org/content/42/2/301
*  Stent assisted coil embolization of wide-necked bilobed anterior inferior cerebellar artery aneurysm with incorporated artery...
Clinical presentation A middle-aged patient was referred for treatment of a bilobed saccular aneurysm identified on a CT angiogram performed for a subarachnoid hemorrhage which occurred 20 days prior to presentation. A diagnostic angiogram showed a bilobed wide-necked saccular aneurysm at the AICA origin with the AICA arising from the dome of the aneurysm and also supplying the territory of the posterior inferior cerebellar artery. The therapeutic procedure involved trans-aneurysmal cannulation of the AICA with the microcatheter left in situ. Another microcatheter was maneuvered into the larger dome of the aneurysm. A stent was then deployed in the basilar artery, jailing the previous microcatheter in the aneurysm. Helical Guglielmi detachable coils were deployed in the ...
  http://jnis.bmj.com/content/early/2012/08/13/neurintsurg-2012-010413
*  Alarmingly High Serious Complication Rate of Stent-Assisted Coiling in Unruptured Intracranial Aneurysms: The Need for...
To the Editor:. We read with interest the results of a large series of patients with intracranial aneurysms treated with stent-assisted coiling.1 A series of 216 patients with aneurysms (181 unruptured and 35 ruptured) were treated with this technique. Direct procedure-related mortality occurred in 10 of 216 (4.6%) and procedure-related permanent neurological deficit occurred in 16 of 216 (7.4%). In other words, 12% of patients either died or had permanent neurological deficit as a direct consequence of the treatment. This is an alarmingly high rate of serious complications, especially in a population harboring mostly unruptured aneurysms (with benign natural history) located on sites that are easily accessible for surgery. We cannot think of an unruptured aneurysm with a cumulative risk that outweighs this ...
  http://stroke.ahajournals.org/content/41/4/e191
*  Are Multiple Intracranial Aneurysms, More Than 5 At One Time, Almost Exclusively A Female Disease? A Clinical Series and...
The clinical characteristics of elderly patients with multiple IAs were studied in 481 patients by Inagawa [31]. Patients were divided into two groups: group 1 - 59 years of age or younger and group 2- 60 years of age or older. Of the 481 patients, 136 (28%) had multiple aneurysms. The percentage of patients with multiple aneurysms was 30% for group 1 and 27% for group 2. The rate of multiple aneurysms was significantly less in males than in females (17% versus 31%). Due to the small sample size, no significant difference could be found between the male and female age groups in terms of the number of aneurysms by gender, yet it is important to highlight that there were no male patients reported in that series with 5 aneurysms or more. The only patients in this series reported to have 5 aneurysms or more were ...
  http://googlescholar.medcraveonline.com/scholars/article_fulltext/174
*  Advance Access: Impact of Young Age on the Presentation of Saccular Intracranial Aneurysms: Population-Based Analysis of 4082...
Unruptured saccular intracranial aneurysm (sIA) is a relatively common disease (2%-3% prevalence).1 Asymptomatic unruptured sIAs are diagnosed increasingly frequently due to improved availability of magnetic resonance imaging (MRI) scans. Although sIAs may rupture causing devastating hemorrhage with mortality of 30% to 50%,2 most sIAs never rupture.3 The pathobiology of sIA formation and rupture need to be elucidated in…
  https://neurosurgerycns.wordpress.com/2017/06/09/advance-access-impact-of-young-age-on-the-presentation-of-saccular-intracranial-aneurysms-population-based-analysis-of-4082-patients/
*  Hemodynamics in intracranial aneurysms
Hemodynamics are considered a risk factor for the initiation, growth and rupture of intracranial aneurysms. In this thesis several aspects of the research of hemodynamics in intracranial aneurysms are discussed. First, I discuss the need to obtain aneurysm hemodynamics in a patient-specific manner, followed by possible clinical routines for obtaining such information. Second, the strengths and limitations of presented studies and the underlying technology are discussed. Third, the main outcome of the comparison study in chapter 10 is absence of additional value of aneurysm hemodynamics for characterization of ruptured versus unruptured aneurysm. This outcome raises questions whether there still is a future for hemodynamics in rupture risk prediction, and whether additional studies are still ...
  http://dare.uva.nl/search?metis.record.id=418247
*  Books by Subject - Lane Medical Library - Stanford University School of Medicine
PART I. Aneurysms and Subarachnoid Hemorrhage -- CASE 1. Embolization of a Ruptured Basilar Tip Aneurysm -- CASE 2. Embolization of a Ruptured Anterior Communicating Artery Aneurysm -- CASE 3. Multiple Aneurysms in a Patient with Subarachnoid Hemorrhage -- CASE 4. Management of an Unruptured Internal Carotid Artery Aneurysm -- CASE 5. Balloon-Assisted Embolization of a Ruptured Wide-Necked Anterior Communicating Artery Aneurysm -- CASE 6. Stent-Assisted Embolization of a Wide-Necked Recurrent Posterior Communicating Artery Aneurysm -- CASE 7. Management of Complications during Aneurysm Coiling: Proximal Mechanically Induced Vasospasm -- CASE 8. Management of Complications ...
  http://lane.stanford.edu/biomed-resources/ebsubjectbrowse.html?m=Radiology&page=1&proxy-links=false
*  Abstract W P76: Parent Artery Curvature May Help Determine the Effectiveness of Flow Diverter Treatment | Stroke
Introduction: Flow diverters (FDs) aim to treat intracranial aneurysms by altering intra-aneurysmal hemodynamics. Reports have suggested aneurysm and parent artery shape may affect flow reduction in FD-treatment. The purpose of this study is to gain insight into the way in which aneurysm shape and parent artery curvature influence the ability of FDs to redirect flow.. Hypothesis: Aneurysm dome size and parent artery curvature affect FD-induced flow reduction within an aneurysm.. Methods: FD models constructed based on the Pipeline Embolization Device with 35% area coverage, 30 um strand diameter, and 4 mm nominal diameter were implemented for hemodynamic simulation analysis. The flow reduction effects were tested using aneurysm models featuring different dome sizes and ...
  http://stroke.ahajournals.org/content/45/Suppl_1/AWP76
*  Acutely ruptured intracranial saccular aneurysms treated with stent assisted coiling: complications and outcomes in 42...
Background Antiplatelet agents are required to prevent thromboembolic complications from recently deployed intracranial stents, yet they carry a risk of bleeding complications that may be serious in patients with recent subarachnoid hemorrhage.. Method Consecutive patients at a single institution who had ruptured intracranial saccular aneurysms treated with stent assisted coiling were retrospectively reviewed. Our primary outcomes were ischemic stroke related to the stent and bleeding complications possibly related to antithrombotic therapy. Secondary outcomes included 3 month follow-up National Institute of Health Stroke Scale (NIHSS) scores and modified Rankin Scale (mRS) scores.. Results 44 aneurysms in 42 patients were treated. Seven patients experienced ischemic strokes during their hospitalization. Five ischemic strokes were secondary to vasospasm; one was definitely related to thrombus formation ...
  http://jnis.bmj.com/content/early/2009/12/03/jnis.2009.001693
*  Plus it
SUMMARY: Giant intracranial aneurysms are rare vascular pathologies associated with high morbidity and mortality. The purpose of this in vivo study was to assess giant intracranial aneurysms and their wall microstructure by 7T MR imaging, previously only visualized in histopathologic examinations. Seven giant intracranial aneurysms were evaluated, and 2 aneurysms were available for histopathologic examination. Six of 7 (85.7%) showed intraluminal thrombus of various sizes. Aneurysm walls were depicted as hypointense in TOF-MRA and SWI sequences with excellent contrast ratios to adjacent brain parenchyma (range, 0.01-0.60 and 0.58-0.96, respectively). The triple-layered microstructure of the aneurysm walls was visualized in all aneurysms in TOF-MRA and SWI. This could be ...
  http://www.ajnr.org/content/early/2015/11/12/ajnr.A4569
*  Computed tomographic demonstration of the effect of proximal parent artery ligation for giant intracranial aneurysms.
Four patients with giant intracranial aneurysms, which measured over 2.5 cm in diameter, were treated by ligation of the proximal parent artery. The location of the aneurysms were intracavernous in two patients, paraophthalmic in one patient, and ver
  http://www.biomedsearch.com/nih/Computed-tomographic-demonstration-effect-proximal/6857483.html