*  Handling Metalloproteinases - Current Protocols
... is polarized by a catalytic metal, usually a zinc ion, and a general base, usually the carboxyl group of a glutamic acid side ... 1 reveal a conserved catalytic domain and a disintegrin‐like domain with a fold homologous to cysteine‐rich domains. J. Mol. ... Large‐scale expression, refolding, and purification of the catalytic domain of human macrophage metalloelastase (MMP‐12) in ... the catalytic activity. As a consequence, these enzymes are generally sensitive to metal chelators. Moreover, the catalytic ...
  http://www.currentprotocols.com/WileyCDA/CPUnit/refId-ps2116.html
*  Patent US7208300 - Member of the lysyl oxidase gene family - Google Patents
The catalytic domain of EER-7 also shares 46% and 66% sequence similarity to the catalytic domains of human LOL and WS914, ... All previously identified lysyl oxidase catalytic domains are present in the EER-7 protein. The catalytic domain of the EER-7 ... EER-7 is comprised of four SRCR domains and a catalytic domain. SRCR domains target proteins to specific extracellular targets. ... sequence identity of its catalytic domain with the catalytic domains of human LO and LOL. ...
  http://www.google.com/patents/US7208300?dq=5787449
*  SMART: FTO NTD domain annotation
This domain is the catalytic AlkB-like domain from the FTO protein (PUBMED:20376003). This domain catalyses a demethylase ... Biochemical assays show that these two domains interact with eachother, which is required for FTO catalytic activity. In ... Evolution (species in which this domain is found). * Taxonomic distribution of proteins containing FTO_NTD domain.. This tree ... FTOcomprises an amino-terminal AlkB-like domain and a carboxy-terminal domain with anovel fold. ...
  http://smart.embl-heidelberg.de/smart/do_annotation.pl?DOMAIN=FTO_NTD&BLAST=DUMMY
*  RCSB PDB for 4AQ0
Details: N-TERMINAL FRAGMENT CORRESPONDING TO CATALYTIC DOMAIN. Gene Name(s): Metabolic Pathways ...
  http://www.rcsb.org/pdb/explore/quickPDB.do?structureId=4AQ0
*  Frontiers | mADP-RTs: versatile virulence factors from bacterial pathogens of plants and mammals | Plant Science
Despite low sequence similarity at the primary amino acid level, mADP-RTs share a conserved core catalytic fold and structural ... Despite low sequence similarity at the primary amino acid level, mADP-RTs share a conserved core catalytic fold and structural ... and consist only of the catalytic domain preceded by a type three secretion signal and host cell targeting domains (Deng and ... Despite a low level of sequence similarity, the catalytic domains of most mADP-RTs share a common core αβ fold (Holbourn et al ...
  https://www.frontiersin.org/articles/10.3389/fpls.2012.00142/full
*  Dlat MGI Mouse Gene Detail - MGI:2385311 - dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
InterPro Domains. IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain. IPR003016 2-oxo acid dehydrogenase, ...
  http://www.informatics.jax.org/marker/MGI:2385311
*  Crystal Structure and Allosteric Activation of Protein Kinase C βII
C1B clamps the novel NFD helix of the catalytic domain in a low-activity conformation. In the isolated PKCβII catalytic domain ... C1B contacts with the catalytic domain mimic membrane and phorbol ester. The C1B and catalytic domain have an extensive ... folded protein domains are represented as rigid bodies. Here, the catalytic domain together with the bound C1B domain and the ... the C2 domain made contact with the C1B domain and/or associated linker regions, but not with the catalytic or C1A domains. ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC3104240/?lang=en-ca
*  UniProt/SWISS-PROT: ASH1L MOUSE
FT REGION 2059 2278 Catalytic domain. {ECO:0000250}. FT COMPBIAS 1378 1422 Pro-rich. FT COMPBIAS 1555 1787 Ser-rich. FT MOD_RES ... FT DOMAIN 2081 2132 AWS. {ECO:0000255,PROSITE- FT ProRule:PRU00562}. FT DOMAIN 2135 2251 SET. {ECO:0000255,PROSITE- FT ProRule: ... ECO:0000255,PROSITE- FT ProRule:PRU00155}. FT DOMAIN 2452 2522 Bromo. {ECO:0000255,PROSITE- FT ProRule:PRU00035}. FT DOMAIN ... Protein domain (28) InterPro (11) Pfam (3) PROSITE (8) SMART (6) Literature (5) PubMed (5) All databases (84) Download RDF ...
  http://www.genome.jp/dbget-bin/www_bget?sp:ASH1L_MOUSE
*  PLB1 Gene - GeneCards | PLB1 Protein | PLB1 Antibody
Domain:. * Repeat 2 contains the catalytic domain. Family:. * Belongs to the GDSL lipolytic enzyme family. Phospholipase B1 ... Domains & Families for PLB1 Gene Gene Families for PLB1 Gene. HGNC:. *467 : Phospholipases ... glycosylated extracellular domain composed of four tandem homologous domains, followed by a hydrophobic segment that anchors ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=PLB1
*  WO2016207384A1 - Method for producing a coffee extract - Google Patents
Catalytic domain: The term 'catalytic domain' means the region of an enzyme containing the catalytic machinery of the enzyme. ... Catalytic Domains In one embodiment, the present invention also relates to catalytic domains having a sequence identity to ... A catalytic domain operably linked to the CBM1 binding domain may be from a hydrolase, isomerase, ligase, lyase, oxidoreductase ... The present invention also relates to polynucleotides encoding a polypeptide, a catalytic domain, or CBM1 binding domain of the ...
  https://patents.google.com/patent/WO2016207384A1/en
*  Structures of ligands docked in the active sites of β- | Open-i
... account for the different catalytic activity and substrate specificity of the various fungal and bacterial β-N- ... account for the different catalytic activity and substrate specificity of the various fungal and bacterial β-N- ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4384365_12859_2015_465_Fig6_HTML&req=4
*  3o64 - Proteopedia, life in 3D
Crystal structure of catalytic domain of TACE with 2-(2-Aminothiazol-4-yl)pyrrolidine-Based Tartrate Diamides. ...
  http://proteopedia.org/wiki/index.php/3o64
*  Protease Assasy Services
Complement MASP3 Catalytic Domain. Other Proteases Airway trypsin-like protease/HAT. Marapsin/Pancreasin. ...
  https://www.genscript.com/protease-assay-services.html
*  Anatomy of a microscopic wood chipper | EurekAlert! Science News
... catalytic domain (CD),' a much smaller 'carbohydrate-binding module (CBM)' and a flexible 'linker domain (LD)' that connects ... IMAGE: This is a photograph of a front and side-views of the catalytic domain of the cellulase TrCel7a shows how the enzyme ... Using the enzyme's genetic blueprint, the researchers made versions of the catalytic domain without the LD and CBM attached. ...
  https://www.eurekalert.org/pub_releases/2015-12/vu-aoa121015.php
*  Complement component 1s - Wikipedia
1elv: CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN COMPLEMENT C1S PROTEASE ... Rossi V, Gaboriaud C, Lacroix M, Ulrich J, Fontecilla-Camps JC, Gagnon J, Arlaud GJ (June 1995). "Structure of the catalytic ... Busby TF, Ingham KC (May 1990). "NH2-terminal calcium-binding domain of human complement C1s- mediates the interaction of C1r- ... 1nzi: Crystal Structure of the CUB1-EGF Interaction Domain of Complement Protease C1s ...
  https://en.wikipedia.org/wiki/Complement_component_1s
*  Rasgrf2 MGI Mouse Gene Detail - MGI:109137 - RAS protein-specific guanine nucleotide-releasing factor 2
IPR001895 Ras guanine-nucleotide exchange factors catalytic domain. IPR000651 Ras-like guanine nucleotide exchange factor, N- ... IPR036964 Ras guanine-nucleotide exchange factor catalytic domain superfamily. IPR019804 Ras guanine-nucleotide exchange factor ... IPR023578 Ras guanine nucleotide exchange factor domain superfamily. ...
  http://www.informatics.jax.org/marker/MGI:109137
*  NIAAA Director's Report on Institute Activities to The 121st Meeting of the National Advisory Council on Alcohol Abuse and...
Their data support the existence of catalytic domain pairs, and glutamate receptor activation in neurons triggered an increase ... Structural Rearrangement of CaMKIIalpha Catalytic Domains Encodes Activation.. At its fundamental level, human memory is ... Recently, crystals of Ca(2+)/calmodulin-dependent protein kinase IIalpha (CaMKIIalpha) catalytic domains, the enzymatic portion ... Structural equation models found that reduced ability in all cognitive domains was predicted by a latent externalizing factor ...
  https://www.niaaa.nih.gov/about-niaaa/our-work/advisory-council/directors-reports-council/niaaa-directors-report-institute-121
*  Adenylyl cyclase - Proteopedia, life in 3D
C-Terminal Catalytic Domain The catalytic activity in Rv1264's is performed by the residues: Asp 222 (Red), Lys 261 (Blue), Asp ... This dimerization places the regulatory domain of chain A in close proximity to the catalytic domain of chain B, and vice versa ... shown that the sequence between the Rv1264 adenylyl cyclases catalytic domain and mammalian adenylyl cyclases catalytic domain ... which separates the monomeric C-terminal catalytic domains of the dimer[16]. This separation of domains lowers their interface ...
  http://proteopedia.org/wiki/index.php/Adenylyl_cyclase
*  PLCB1 (phospholipase C, beta 1 (phosphoinositide-specific))
PH = Pleckstrin Homology Domain; EF = EF-Hand Domain; X and Y = Catalytic Domain;. C2 = Calcium-binding Domain;. NLS = Nuclear ... Two additional modules are also present: an EF-hand domain, located between the PH and X domains, and a C2 domain, which is ... Domain families : Pfam (NCBI). pfam06631 pfam09279 pfam00388 pfam00387 pfam08703 Domain families : Smart (EMBL). C2 (SM00239) ... Protein : pattern, domain, 3D structure. UniProt/SwissProt. Q9NQ66 [function] [subcellular_location] [family_and_domains] [ ...
  http://atlasgeneticsoncology.org/Genes/GC_PLCB1.html
*  Patents filed at Sep 05 2017 | Self-adaptive, ultra-low elastic modulus shape memory alloys | Patents.com
Multi-domain recombinant proteins have a cutinase catalytic domain. The cutinase catalytic domain is a modular domain, which ... A thermostable .beta.-glucosidase including a .beta.-glucosidase catalytic domain, the .beta.-glucosidase catalytic domain ... Multi-domain enzymes having cutinase activity, compositions comprising same and uses thereof. ...
  http://www.patents.com/isd-20170905-p33.html
*  IJMS | Free Full-Text | Transcriptional Regulation of a Chitinase Gene by 20-Hydroxyecdysone and Starvation in the Oriental...
... a single catalytic domain and no CBD, which is similar to the domain architecture of Group IV chitinases [10]. The presence of ... including a signal peptide and a single catalytic domain. The glycosylhydrolase_18 conserved domain (FDGLDLDWE) was found in ... Figure 2. Phylogenetic analysis of chitinase and chitinase-like proteins from three insect species based on catalytic domain ... Figure 2. Phylogenetic analysis of chitinase and chitinase-like proteins from three insect species based on catalytic domain ...
  http://mdpi.com/1422-0067/14/10/20048/htm
*  Bphyt 7230 - Ribulose-bisphosphate carboxylase - Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN) - Bphyt...
Cluster: Ribulose bisphosphate carboxylase large chain, catalytic domain protein. 216. Full view ... domains_section' target='_top'>More...,/a>,/p>Family & Domainsi. Domains and Repeats. Feature key. Position(s). Description ... help/domain' target='_top'>More...,/a>,/p>Domaini. 25 - 138. RuBisCO_large_NInterPro annotation. ,p>Information which has been ... help/domain' target='_top'>More...,/a>,/p>Domaini. 148 - 428. RuBisCO_largeInterPro annotation. ,p>Information which has been ...
  http://www.uniprot.org/uniprot/B2TAL3
*  AZC 2687 - Ribulose-bisphosphate carboxylase - Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 ...
Cluster: Ribulose bisphosphate carboxylase large chain, catalytic domain protein. 185. Full view ... domains_section' target='_top'>More...,/a>,/p>Family & Domainsi. Domains and Repeats. Feature key. Position(s). Description ... help/domain' target='_top'>More...,/a>,/p>Domaini. 15 - 128. RuBisCO_large_NInterPro annotation. ,p>Information which has been ... help/domain' target='_top'>More...,/a>,/p>Domaini. 139 - 418. RuBisCO_largeInterPro annotation. ,p>Information which has been ...
  http://www.uniprot.org/uniprot/A8I8P2
*  High‐efficiency bypass of DNA damage by human DNA polymerase Q | The EMBO Journal
Sequence inserts in the POLQ catalytic domain. Like other DNA polymerases, enzymes of the A‐family have a structure that can be ... domain organization with a helicase‐like domain in the N‐terminal portion, a less conserved central domain, which is largely ... The 5′ nuclease domains of both chains were removed in silico. The polymerase domain of human POLQ has 515 residues, while that ... Sequence insertions in the catalytic site of POLQ. (A) The DNA polymerase catalytic region of POLQ is shown in relation to the ...
  http://emboj.embopress.org/content/23/22/4484