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*  Clinical efficacy and safety of a once-daily formulation of carbimazole in cats with hyperthyroidism - Frénais - 2009 - Journal...
K. E. Hill, P. C. Mills, B. R. Jones, C. F. Bolwell, D. Aberdein, J. P. Chambers, Percutaneous absorption of methimazole: anin ... Results:The median dose of carbimazole was 10 mg (range 10 to 15 mg) and 15 mg (5 to 25 mg) once daily after 3 and 53 weeks, ... Objective:Evaluation of efficacy and safety of a novel controlled-release formulation of carbimazole in feline hyperthyroidism. ... Clinical Significance:Once daily administration of controlled-release carbimazole tablets was effective and had expected ...
  http://onlinelibrary.wiley.com/doi/10.1111/j.1748-5827.2009.00772.x/full
*  Antithyroid agent - Wikipedia
The main antithyroid drugs are carbimazole (in the UK), methimazole (in the US), and propylthiouracil/PTU. A less common ... A randomized control trial testing single dose treatment for Graves' found methimazole achieved euthyroid state more ... "Efficacy of single daily dosage of methimazole vs. propylthiouracil in the induction of euthyroidism". Clin. Endocrinol. 54 (3 ... "Agranulocytosis with tonsillitis associated with methimazole therapy". Brazilian journal of otorhinolaryngology. 71 (3): 374- ...
  https://en.wikipedia.org/wiki/Antithyroid_agent
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*  Microarray Analysis of Scalp Biopsies After Minoxidil Treatment - Full Text View - ClinicalTrials.gov
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  https://clinicaltrials.gov/show/NCT01309191
*  Patent US8147561 - Methods and devices to curb appetite and/or reduce food intake - Google Patents
... carbimazole, methimazole, methylthiouracil and propylthiouracil. ... 2. Anti-thyroid drugs used in therapy: carbimazole, methimazole ... methimazole, methylthiouracil and propylthiouracil.. In another embodiment of the devices of the present invention the ... methimazole, methylthiouracil and propylthiouracil.. In another embodiment of the methods of the present invention, the ...
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*  November 2016 | American Thyroid Association
HLA-B*38:02:01 predicts carbimazole/ methimazole-induced agranulocytosis. Clin Pharmacol Ther 2016;99:555-61. Epub January 12, ...
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These drugs (Methimazole and Propylthiouracil in the United States, Carbimazole in Europe) are usually very well tolerated. ... Methimazole, carbimazole and propylthiouracil (PTU) are used to treat hyperthyroidism, especially when it is caused by Graves' ... Hyperthyroidism may be treated with antithyroid medications (methimazole, carbimazole, propylthiouracil), radioactive iodine or ... All patients started treatment with Carbimazole and about 10% of the patients were later switched to Propylthiouracil because ...
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Methimazole and carbimazole are interchangeable because carbimazole is completely metabolized to methimazole. The carbimazole ... Propylthiouracil (PTU) and methimazole are the thionamide drugs available in the United States. Carbimazole is a third option ... However, methimazole has several important pharmacokinetic advantages over PTU:. ●The serum half-life of methimazole is four to ... Methimazole-induced agranulocytosis in patients with Graves' disease is more frequent with an initial dose of 30 mg daily than ...
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Both propylthiouracil (PTU) and methimazole (from carbimazole) are detected in breast milk but appear not to affect neonatal ... Jansson R, Dahlberg PA, Lindstrom B. Comparative bioavailability of carbimazole and methimazole. Int J Clin Pharmacol Ther ... 67 Carbimazole is rapidly converted in the liver into methimazole,69 which is the preparation available in the United States. ... Effect of methimazole treatment of maternal thyrotoxicosis on thyroid function in breast-feeding infants. J Pediatr1996;128:855 ...
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Jansson R, Dahlberg PA, Lindstrom B. Comparative bioavailability of carbimazole and methimazole. Int J Clin Pharmacol Ther ... disease with high-dose carbimazole plus thyroxine versus low-dose carbimazole. Clin Endocrinol (Oxf.) 1998; 48: 585-592. ... Effect of methimazole, with or without L-thyroxine, on remission rates in Graves' disease. J Clin Endocrinol Metab 1998; 83: ... The effect of methimazole on cure rates after radioiodine treatment for Graves' hyperthyroidism: a randomized cli nical trial. ...
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*  The Hospital for Sick Children - Hyperthyroidism during pregnancy
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*  Your Cat | Hyperthyroidism in cats | Indepth Cat Articles
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*  A Categorical Structure-Activity Relationship Analysis of the Developmental Toxicity of Antithyroid Drugs | International...
Carbimazole, a metabolic precursor of methimazole, is available in some countries outside of the US. In the US propylthiouracil ... methimazole, and carbimazole were observed to share some structural features relating to human developmental toxicity. Thus ... all three agents are extremely limited and insufficient to support a policy given the broad use of methimazole and carbimazole ... is recommended because of concern about developmental toxicity from methimazole and carbimazole. Despite this recommendation, ...
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