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K. E. Hill, P. C. Mills, B. R. Jones, C. F. Bolwell, D. Aberdein, J. P. Chambers, Percutaneous absorption of methimazole: anin ... Results:The median dose of carbimazole was 10 mg (range 10 to 15 mg) and 15 mg (5 to 25 mg) once daily after 3 and 53 weeks, ... Objective:Evaluation of efficacy and safety of a novel controlled-release formulation of carbimazole in feline hyperthyroidism. ... Clinical Significance:Once daily administration of controlled-release carbimazole tablets was effective and had expected ...
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The main antithyroid drugs are carbimazole (in the UK), methimazole (in the US), and propylthiouracil/PTU. A less common ... A randomized control trial testing single dose treatment for Graves' found methimazole achieved euthyroid state more ... "Efficacy of single daily dosage of methimazole vs. propylthiouracil in the induction of euthyroidism". Clin. Endocrinol. 54 (3 ... "Agranulocytosis with tonsillitis associated with methimazole therapy". Brazilian journal of otorhinolaryngology. 71 (3): 374- ...
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HLA-B*38:02:01 predicts carbimazole/ methimazole-induced agranulocytosis. Clin Pharmacol Ther 2016;99:555-61. Epub January 12, ...
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These drugs (Methimazole and Propylthiouracil in the United States, Carbimazole in Europe) are usually very well tolerated. ... Methimazole, carbimazole and propylthiouracil (PTU) are used to treat hyperthyroidism, especially when it is caused by Graves' ... Hyperthyroidism may be treated with antithyroid medications (methimazole, carbimazole, propylthiouracil), radioactive iodine or ... All patients started treatment with Carbimazole and about 10% of the patients were later switched to Propylthiouracil because ...
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Both propylthiouracil (PTU) and methimazole (from carbimazole) are detected in breast milk but appear not to affect neonatal ... Jansson R, Dahlberg PA, Lindstrom B. Comparative bioavailability of carbimazole and methimazole. Int J Clin Pharmacol Ther ... 67 Carbimazole is rapidly converted in the liver into methimazole,69 which is the preparation available in the United States. ... Effect of methimazole treatment of maternal thyrotoxicosis on thyroid function in breast-feeding infants. J Pediatr1996;128:855 ...
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