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*  Adoptive immunotherapy of cancer: accomplishments and prospects.
Recent developments in modern cellular immunology have expanded the opportunities for utilizing adoptive immunotherapy in human ... Adoptive immunotherapy is an approach to cancer treatment that has not received significant evaluation in cancer patients. ... Adoptive immunotherapy is an approach to cancer treatment that has not received significant evaluation in cancer patients. ... Adoptive immunotherapy is an approach to the treatment of cancer that deserves further study.. ...
  http://www.biomedsearch.com/nih/Adoptive-immunotherapy-cancer-accomplishments-prospects/6362866.html
*  A New Approach to Simultaneously Quantify Both TCR α- and β-Chain Diversity after Adoptive Immunotherapy | Clinical Cancer...
A New Approach to Simultaneously Quantify Both TCR α- and β-Chain Diversity after Adoptive Immunotherapy. Minying Zhang, ... A New Approach to Simultaneously Quantify Both TCR α- and β-Chain Diversity after Adoptive Immunotherapy ... A New Approach to Simultaneously Quantify Both TCR α- and β-Chain Diversity after Adoptive Immunotherapy ... A New Approach to Simultaneously Quantify Both TCR α- and β-Chain Diversity after Adoptive Immunotherapy ...
  http://clincancerres.aacrjournals.org/content/18/17/4733
*  Abstract A017: Method for molecular characterization of antigens, epitopes and T cell receptors for adoptive CD4 immunotherapy ...
Recent advances in cellular immunotherapy show that cancer cells can be efficiently eliminated by adoptive transfer of modified ... Abstract A017: Method for molecular characterization of antigens, epitopes and T cell receptors for adoptive CD4 immunotherapy ... Abstract A017: Method for molecular characterization of antigens, epitopes and T cell receptors for adoptive CD4 immunotherapy ... Method for molecular characterization of antigens, epitopes and T cell receptors for adoptive CD4 immunotherapy [abstract]. In ...
  http://cancerimmunolres.aacrjournals.org/content/4/11_Supplement/A017
*  Pilot Study of Sentinel-Node-Based Adoptive Immunotherapy in Advanced Colorectal Cancer
... Mona Karlsson, PhD,1 Per Marits, PhD,1 ... Vaccination trials have shown promising results in colorectal cancer patients.15-17 Adoptive immunotherapy, including ... Colon cancer survival rates with the new American Joint Committee on Cancer sixth edition staging. J Natl Cancer Inst. 2004;96: ... tumour reactive lymphocytes identified intraoperatively for the use in immunotherapy of colon cancer. Br J Cancer. 2006;94:1478 ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2889279/
*  T Cell Adoptive Immunotherapy of Newly Diagnosed Gliomas | Clinical Cancer Research
T Cell Adoptive Immunotherapy of Newly Diagnosed Gliomas. Gregory E. Plautz, David W. Miller, Gene H. Barnett, Glen H. J. ... T Cell Adoptive Immunotherapy of Newly Diagnosed Gliomas. Gregory E. Plautz, David W. Miller, Gene H. Barnett, Glen H. J. ... T Cell Adoptive Immunotherapy of Newly Diagnosed Gliomas. Gregory E. Plautz, David W. Miller, Gene H. Barnett, Glen H. J. ... T Cell Adoptive Immunotherapy of Newly Diagnosed Gliomas Message Subject (Your Name) has forwarded a page to you from Clinical ...
  http://clincancerres.aacrjournals.org/content/6/6/2209
*  BRAF Inhibition Increases Tumor Infiltration by T cells and Enhances the Antitumor Activity of Adoptive Immunotherapy in Mice |...
BRAF Inhibitor Vemurafenib Improves the Antitumor Activity of Adoptive Cell Immunotherapy. Cancer Res 2012;72:3928-37. ... Cancer immunotherapy: a treatment for the masses. Science 2004;305:200-5. ... BRAF Inhibition Increases Tumor Infiltration by T cells and Enhances the Antitumor Activity of Adoptive Immunotherapy in Mice. ... BRAF Inhibition Increases Tumor Infiltration by T cells and Enhances the Antitumor Activity of Adoptive Immunotherapy in Mice ...
  http://clincancerres.aacrjournals.org/content/19/2/393?rss=1
*  Differences in the Effects of Host Suppression on the Adoptive Immunotherapy of Subcutaneous and Visceral Tumors | Cancer...
Cancer Research Online ISSN: 1538-7445. Cancer Research Print ISSN: 0008-5472. Journal of Cancer Research ISSN: 0099-7013. ... Thus, suppression of adoptive immunotherapy appears to be relevant to tumors confined to the skin and subcutaneous tissue but ... The adoptive immunotherapy of intradermal MCA 105 tumor with immune cells required prior immunosuppression of the recipient by ... Differences in the Effects of Host Suppression on the Adoptive Immunotherapy of Subcutaneous and Visceral Tumors. Alfred E. ...
  http://cancerres.aacrjournals.org/content/46/7/3426
*  Endothelial Activation and Blood-Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells |...
Your Name) has forwarded a page to you from Cancer Discovery Message Body (Your Name) thought you would be interested in this ... Endothelial Activation and Blood-Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells. ... Endothelial Activation and Blood-Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells ... Endothelial Activation and Blood-Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells ...
  http://cancerdiscovery.aacrjournals.org/content/early/2017/10/10/2159-8290.CD-17-0698
*  The role of tumor-specific Lyt-1+2- T cells in eradicating tumor cells in vivo. I. Lyt-1+2- T cells do not necessarily require...
In contrast, the adoptive transfer of Lyt-1+2- anti-X5563 immune T cells into B cell mice produced complete protection against ... Implications for cancer immunotherapy by adoptive T cell transfer.. *Alexandre Corthay, Kristina Berg Lorvik, Bjarne Bogen ... This information is current as Genomics Immunotherapy : The Choice of Personalized Tapping CD 4 T Cells for Cancer. *Maurizio ... Is secretion of tumour-specific antigen important for cancer eradication by CD4(+) T cells?-- ...
  https://www.semanticscholar.org/paper/The-role-of-tumor-specific-Lyt-1%2B2-T-cells-in-tumor-Fujiwara-Fukuzawa/229c8a19c52e681e32b2203dde3a1bcac30c7e02
*  Review: Adoptive immunotherapy against ovarian cancer Ovarian Cancer and Us OVARIAN CANCER and US ...
Sandi Pniauskas Ovarian Cancer and Us Sandi Pniauskas ovarian cancer and related concerns: genetics, treatments, education, ... Adoptive cell-therapy has been shown to be an active treatment for different kinds of cancers, such as melanoma and other solid ... Adoptive immunotherapy seems to be generally well-tolerated and toxicities reported are especially related to use of cytokines ... However, clinical research is still at an early stage and only few evidences of efficacy of adoptive immunotherapy in EOC have ...
  https://ovariancancerandus.blogspot.com/2016/05/review-adoptive-immunotherapy-against.html
*  Effective adoptive immunotherapy of triple-negative breast cancer by folate receptor-alpha redirected CAR T cells is influenced...
... the pre-selection of patients with high antigen expression levels when utilizing CAR-based adoptive T cell therapies of cancer ... may represent an ideal tumor-associated marker for immunotherapy for TNBC. The aim of the present study was to apply a chimeric ... The poor prognosis and the limited efficacy of targeted therapy in patients with triple-negative breast cancer (TNBC) have ... Effective adoptive immunotherapy of triple-negative breast cancer by folate receptor-alpha redirected CAR T cells is influenced ...
  https://jhoonline.biomedcentral.com/articles/10.1186/s13045-016-0285-y
*  Wiley Online Library: Search Results Page
Implications for Cancer Immunotherapy by Adoptive T Cell Transfer. Scandinavian Journal of Immunology. Volume 73, Issue 6, June ... From cancer immunosurveillance to cancer immunotherapy. Immunological Reviews. Volume 220, Issue 1, December 2007, Pages: 82- ... Cytokines in cancer immunity and immunotherapy. Immunological Reviews. Volume 202, Issue 1, December 2004, Pages: 275-293, Mark ... Revisiting cancer immunoediting by understanding cancer immune complexity. The Journal of Pathology. Volume 224, Issue 1, May ...
  http://onlinelibrary.wiley.com/advanced/search/results?articleDoi=10.1034/j.1600-065X.2002.18801.x&scope=allContent&start=1&resultsPerPage=20
*  The achievement of adoptive T cell-based immunotherapy (ACT) in cancer is | Discovery of a novel TLR2 signaling inhibitor with...
The achievement of adoptive T cell-based immunotherapy (ACT) in cancer is. Posted on November 25, 2017 by Dana Obrien ... The achievement of adoptive T cell-based immunotherapy (ACT) in cancer is limited in part by the deposition of myeloid-derived ... Extension of this extensive analysis can enable the advancement of better strategies to boost Action replies in cancers. turned ...
  http://research-matters.net/the-achievement-of-adoptive-t-cell-based-immunotherapy-act-in-cancer-is/
*  May 1990 - Scientific American
Adoptive Immunotherapy for Cancer. Also called cell-transfer therapy, it is one of a new class of approaches being developed to ... strengthen the innate ability of the immune system to fight cancer ...
  https://www.scientificamerican.com/magazine/sa/1990/05-01/
*  Protocols and Video Articles Authored by Caius G. Radu
Imaging Adoptive Cell Transfer Based Cancer Immunotherapy Current Pharmaceutical Biotechnology. Sep, 2010 , Pubmed ID: 20497110 ... PET Imaging of Cancer Immunotherapy Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jun, 2008 ... Dec, 2011 , Pubmed ID: 22123951 The goal of cancer immunotherapy is the generation of an effective, stable, and self-renewing ... Oct, 2012 , Pubmed ID: 23052208 Immunotherapy aims to re-engage and revitalize the immune system in the fight against cancer. ...
  https://www.jove.com/author/Caius+G._Radu
*  A novel series of conferences tackling the hurdles confronting the translation of novel cancer immunotherapies | Journal of...
... the heterogeneity of cancer and the limited efficacy profile of current immunotherapy platforms are the two main hurdles. ... clinical data of several approaches point to a roadmap that carries the promise to significantly advance cancer immunotherapy. ... year and outlines the focus of the second meeting to be held in 2013 that will be dedicated to stem cells and immunotherapy. ... Restifo NP, Dudley ME, Rosenberg SA: Adoptive immunotherapy for cancer: harnessing the T cell response. Nat Rev Immunol. 2012, ...
  https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-10-218
*  Daniel J. Powell Jr. | Members | Institute for Translational Medicine and Therapeutics | Perelman School of Medicine at the...
Cancer immunotherapy with a focus on adoptive T cell transfer and cancer vaccination.. Selected Publications. Ye Q, Song D, ... A universal strategy for adoptive immunotherapy of cancer through use of a novel T cell antigen receptor. Cancer Research 72(7 ... Rethinking Ovarian Cancer II: A Roadmap for Reducing Mortality from High-grade Serous Ovarian Cancer. Nature Reviews Cancer 15( ... One obstacle to successful immunotherapy is the lack of highly avid, tumor-reactive T cells in multiple cancers. One current ...
  http://www.med.upenn.edu/apps/faculty/index.php/g5455356/p8186734
*  Adoptive immunotherapy with MUC1-mRNA transfected dendritic cells and cytotoxic lymphocytes plus gemcitabine for unresectable...
AIT with MUC1-DCs and MUC1-CTLs plus GEM may be a feasible and effective treatment for pancreatic cancer. ... Forty-two patients with unresectable or recurrent pancreatic cancer were treated. DCs were generated by culture with ... a human pancreatic cancer cell line, and then with interleukin-2. Patients were treated with GEM, while MUC1-DCs were ... we performed combination therapy with AIT and GEM for patients with unresectable or recurrent pancreatic cancer. ...
  https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-12-175
*  "Active Immunotherapy and Adoptive Cell Transfer as an Effective Cancer" by Philip Jay Cynamon
... and that there is potential for adoptive cell transfer to be adopted as a widespread effective treatment for cancer. ... To fight cancer effectively, T cells must be able to recognize cancerous antigens and the environment in which these T cells ... Moreover, the results of adoptive cell transfer are more positive when patients' own T cells are used. These findings show that ... This paper discusses a method of providing such an environment called adoptive cell transfer, as well as the elements that ...
  https://touroscholar.touro.edu/sjlcas/vol9/iss1/8/
*  Immunotherapy - Wikipedia
Kang N, Zhou J, Zhang T, Wang L, Lu F, Cui Y, Cui L, He W (August 2009). "Adoptive immunotherapy of lung cancer with ... Activation immunotherapies[edit]. Cancer[edit]. Main article: Cancer immunotherapy. Cancer immunotherapy attempts to stimulate ... International Society for Biological Therapy of Cancer. *Cancer Research Institute Annual International Cancer Immunotherapy ... "Adoptive cell transfer: A clinical path to effective cancer immunotherapy". Nature Reviews Cancer. 8 (4): 299-308. doi:10.1038 ...
  https://en.wikipedia.org/wiki/Immunomodulators
*  Frontiers | Immunological and Translational Aspects of NK Cell-Based Antitumor Immunotherapies | Immunology
Additionally, we discuss the use of chimeric-antigen-receptor (CARs) engineered NK cells in cancer immunotherapy. ... Additionally, we discuss the use of chimeric-antigen-receptor (CARs) engineered NK cells in cancer immunotherapy. ... cells play a pivotal role in the first line of defence against cancer. NK cells that are deficient in CD3 and a clonal T cell ... cells play a pivotal role in the first line of defence against cancer. NK cells that are deficient in CD3 and a clonal T cell ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2016.00492/full
*  Frontiers | The Rise of Allogeneic Natural Killer Cells As a Platform for Cancer Immunotherapy: Recent Innovations and Future...
As NK cells in cancer patients are highly dysfunctional and reduced in number, adoptive transfer of large numbers of cytolytic ... As NK cells in cancer patients are highly dysfunctional and reduced in number, adoptive transfer of large numbers of cytolytic ... NK cells and their potential to induce relevant anti-tumor responses are widely explored in cancer immunotherapy. Early studies ... NK cells and their potential to induce relevant anti-tumor responses are widely explored in cancer immunotherapy. Early studies ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2017.00631/full
*  2018 Salon Winners
Adoptive Cell Transfer: A New Type of Cancer Immunotherapy. Award of Merit. ... ATR-inhibitor: A Novel Approach to Targeting the Achilles' Heel of Cancer. Award of Merit. ...
  https://ami.org/medical-illustration/view-art-and-animations/2018-salon-winners
*  Integrating T cell metabolism in cancer immunotherapy, Cancer Letters | 10.1016/j.canlet.2017.09.039 | DeepDyve
Cancer Letters" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications ... IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy ... Integrating T cell metabolism in cancer immunotherapy. Integrating T cell metabolism in cancer immunotherapy Dugnani, Erica; ... Integrating T cell metabolism in cancer immunotherapy. Dugnani, Erica; Pasquale, Valentina; Bordignon, Carlotta; Canu, Adriana ...
  https://www.deepdyve.com/lp/elsevier/integrating-t-cell-metabolism-in-cancer-immunotherapy-pKz7U2t3W5
*  Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem...
Bladder cancerCancer stem cellsImmunotherapyNatural killer cells. Background. Bladder cancer (BC) is the most common malignancy ... Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem- ... Cancer stem-like cells contribute to cisplatin resistance and progression in bladder cancer. Cancer Lett. 2012;322:70-7.View ... cell-based adoptive immunotherapy against chemoresistant bladder cancer stem-like cells (CSCs) in a pre-clinical relevant model ...
  https://0-bmcmedicine-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/s12916-016-0715-2