*  Adoptive immunotherapy of cancer: accomplishments and prospects.
Recent developments in modern cellular immunology have expanded the opportunities for utilizing adoptive immunotherapy in human ... Adoptive immunotherapy is an approach to cancer treatment that has not received significant evaluation in cancer patients. ... Adoptive immunotherapy is an approach to cancer treatment that has not received significant evaluation in cancer patients. ... Adoptive immunotherapy is an approach to the treatment of cancer that deserves further study.. ...
  http://www.biomedsearch.com/nih/Adoptive-immunotherapy-cancer-accomplishments-prospects/6362866.html
*  A New Approach to Simultaneously Quantify Both TCR α- and β-Chain Diversity after Adoptive Immunotherapy | Clinical Cancer...
A New Approach to Simultaneously Quantify Both TCR α- and β-Chain Diversity after Adoptive Immunotherapy. Minying Zhang, ... A New Approach to Simultaneously Quantify Both TCR α- and β-Chain Diversity after Adoptive Immunotherapy ... A New Approach to Simultaneously Quantify Both TCR α- and β-Chain Diversity after Adoptive Immunotherapy ... A New Approach to Simultaneously Quantify Both TCR α- and β-Chain Diversity after Adoptive Immunotherapy ...
  http://clincancerres.aacrjournals.org/content/18/17/4733
*  Pilot Study of Sentinel-Node-Based Adoptive Immunotherapy in Advanced Colorectal Cancer
... Mona Karlsson, PhD,1 Per Marits, PhD,1 ... Vaccination trials have shown promising results in colorectal cancer patients.15-17 Adoptive immunotherapy, including ... Colon cancer survival rates with the new American Joint Committee on Cancer sixth edition staging. J Natl Cancer Inst. 2004;96: ... tumour reactive lymphocytes identified intraoperatively for the use in immunotherapy of colon cancer. Br J Cancer. 2006;94:1478 ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2889279/
*  Abstract A017: Method for molecular characterization of antigens, epitopes and T cell receptors for adoptive CD4 immunotherapy ...
Recent advances in cellular immunotherapy show that cancer cells can be efficiently eliminated by adoptive transfer of modified ... Abstract A017: Method for molecular characterization of antigens, epitopes and T cell receptors for adoptive CD4 immunotherapy ... Abstract A017: Method for molecular characterization of antigens, epitopes and T cell receptors for adoptive CD4 immunotherapy ... Method for molecular characterization of antigens, epitopes and T cell receptors for adoptive CD4 immunotherapy [abstract]. In ...
  http://cancerimmunolres.aacrjournals.org/content/4/11_Supplement/A017
*  T Cell Adoptive Immunotherapy of Newly Diagnosed Gliomas | Clinical Cancer Research
T Cell Adoptive Immunotherapy of Newly Diagnosed Gliomas. Gregory E. Plautz, David W. Miller, Gene H. Barnett, Glen H. J. ... T Cell Adoptive Immunotherapy of Newly Diagnosed Gliomas. Gregory E. Plautz, David W. Miller, Gene H. Barnett, Glen H. J. ... T Cell Adoptive Immunotherapy of Newly Diagnosed Gliomas. Gregory E. Plautz, David W. Miller, Gene H. Barnett, Glen H. J. ... T Cell Adoptive Immunotherapy of Newly Diagnosed Gliomas Message Subject (Your Name) has forwarded a page to you from Clinical ...
  http://clincancerres.aacrjournals.org/content/6/6/2209
*  BRAF Inhibition Increases Tumor Infiltration by T cells and Enhances the Antitumor Activity of Adoptive Immunotherapy in Mice |...
BRAF Inhibitor Vemurafenib Improves the Antitumor Activity of Adoptive Cell Immunotherapy. Cancer Res 2012;72:3928-37. ... Cancer immunotherapy: a treatment for the masses. Science 2004;305:200-5. ... BRAF Inhibition Increases Tumor Infiltration by T cells and Enhances the Antitumor Activity of Adoptive Immunotherapy in Mice. ... BRAF Inhibition Increases Tumor Infiltration by T cells and Enhances the Antitumor Activity of Adoptive Immunotherapy in Mice ...
  http://clincancerres.aacrjournals.org/content/19/2/393?rss=1
*  Differences in the Effects of Host Suppression on the Adoptive Immunotherapy of Subcutaneous and Visceral Tumors | Cancer...
Cancer Research Online ISSN: 1538-7445. Cancer Research Print ISSN: 0008-5472. Journal of Cancer Research ISSN: 0099-7013. ... Thus, suppression of adoptive immunotherapy appears to be relevant to tumors confined to the skin and subcutaneous tissue but ... The adoptive immunotherapy of intradermal MCA 105 tumor with immune cells required prior immunosuppression of the recipient by ... Differences in the Effects of Host Suppression on the Adoptive Immunotherapy of Subcutaneous and Visceral Tumors. Alfred E. ...
  http://cancerres.aacrjournals.org/content/46/7/3426
*  Endothelial Activation and Blood-Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells |...
Your Name) has forwarded a page to you from Cancer Discovery Message Body (Your Name) thought you would be interested in this ... Endothelial Activation and Blood-Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells. ... Endothelial Activation and Blood-Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells ... Endothelial Activation and Blood-Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells ...
  http://cancerdiscovery.aacrjournals.org/content/early/2017/10/10/2159-8290.CD-17-0698
*  Review: Adoptive immunotherapy against ovarian cancer Ovarian Cancer and Us OVARIAN CANCER and US ...
Sandi Pniauskas Ovarian Cancer and Us Sandi Pniauskas ovarian cancer and related concerns: genetics, treatments, education, ... Adoptive cell-therapy has been shown to be an active treatment for different kinds of cancers, such as melanoma and other solid ... Adoptive immunotherapy seems to be generally well-tolerated and toxicities reported are especially related to use of cytokines ... However, clinical research is still at an early stage and only few evidences of efficacy of adoptive immunotherapy in EOC have ...
  https://ovariancancerandus.blogspot.com/2016/05/review-adoptive-immunotherapy-against.html
*  Effective adoptive immunotherapy of triple-negative breast cancer by folate receptor-alpha redirected CAR T cells is influenced...
... the pre-selection of patients with high antigen expression levels when utilizing CAR-based adoptive T cell therapies of cancer ... may represent an ideal tumor-associated marker for immunotherapy for TNBC. The aim of the present study was to apply a chimeric ... The poor prognosis and the limited efficacy of targeted therapy in patients with triple-negative breast cancer (TNBC) have ... Effective adoptive immunotherapy of triple-negative breast cancer by folate receptor-alpha redirected CAR T cells is influenced ...
  https://jhoonline.biomedcentral.com/articles/10.1186/s13045-016-0285-y
*  Wiley Online Library: Search Results Page
Implications for Cancer Immunotherapy by Adoptive T Cell Transfer. Scandinavian Journal of Immunology. Volume 73, Issue 6, June ... From cancer immunosurveillance to cancer immunotherapy. Immunological Reviews. Volume 220, Issue 1, December 2007, Pages: 82- ... Cytokines in cancer immunity and immunotherapy. Immunological Reviews. Volume 202, Issue 1, December 2004, Pages: 275-293, Mark ... Revisiting cancer immunoediting by understanding cancer immune complexity. The Journal of Pathology. Volume 224, Issue 1, May ...
  http://onlinelibrary.wiley.com/advanced/search/results?articleDoi=10.1034/j.1600-065X.2002.18801.x&scope=allContent&start=1&resultsPerPage=20
*  May 1990 - Scientific American
Adoptive Immunotherapy for Cancer. Also called cell-transfer therapy, it is one of a new class of approaches being developed to ... strengthen the innate ability of the immune system to fight cancer ...
  https://www.scientificamerican.com/magazine/sa/1990/05-01/
*  Protocols and Video Articles Authored by Caius G. Radu
Imaging Adoptive Cell Transfer Based Cancer Immunotherapy Current Pharmaceutical Biotechnology. Sep, 2010 , Pubmed ID: 20497110 ... PET Imaging of Cancer Immunotherapy Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jun, 2008 ... Dec, 2011 , Pubmed ID: 22123951 The goal of cancer immunotherapy is the generation of an effective, stable, and self-renewing ... Oct, 2012 , Pubmed ID: 23052208 Immunotherapy aims to re-engage and revitalize the immune system in the fight against cancer. ...
  https://www.jove.com/author/Caius+G._Radu
*  A novel series of conferences tackling the hurdles confronting the translation of novel cancer immunotherapies | Journal of...
... the heterogeneity of cancer and the limited efficacy profile of current immunotherapy platforms are the two main hurdles. ... clinical data of several approaches point to a roadmap that carries the promise to significantly advance cancer immunotherapy. ... year and outlines the focus of the second meeting to be held in 2013 that will be dedicated to stem cells and immunotherapy. ... Restifo NP, Dudley ME, Rosenberg SA: Adoptive immunotherapy for cancer: harnessing the T cell response. Nat Rev Immunol. 2012, ...
  https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-10-218
*  Daniel J. Powell Jr. | Members | Institute for Translational Medicine and Therapeutics | Perelman School of Medicine at the...
Cancer immunotherapy with a focus on adoptive T cell transfer and cancer vaccination.. Selected Publications. Ye Q, Song D, ... A universal strategy for adoptive immunotherapy of cancer through use of a novel T cell antigen receptor. Cancer Research 72(7 ... Rethinking Ovarian Cancer II: A Roadmap for Reducing Mortality from High-grade Serous Ovarian Cancer. Nature Reviews Cancer 15( ... One obstacle to successful immunotherapy is the lack of highly avid, tumor-reactive T cells in multiple cancers. One current ...
  http://www.med.upenn.edu/apps/faculty/index.php/g5455356/p8186734
*  Adoptive immunotherapy with MUC1-mRNA transfected dendritic cells and cytotoxic lymphocytes plus gemcitabine for unresectable...
AIT with MUC1-DCs and MUC1-CTLs plus GEM may be a feasible and effective treatment for pancreatic cancer. ... Forty-two patients with unresectable or recurrent pancreatic cancer were treated. DCs were generated by culture with ... a human pancreatic cancer cell line, and then with interleukin-2. Patients were treated with GEM, while MUC1-DCs were ... we performed combination therapy with AIT and GEM for patients with unresectable or recurrent pancreatic cancer. ...
  https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-12-175
*  "Active Immunotherapy and Adoptive Cell Transfer as an Effective Cancer" by Philip Jay Cynamon
... and that there is potential for adoptive cell transfer to be adopted as a widespread effective treatment for cancer. ... To fight cancer effectively, T cells must be able to recognize cancerous antigens and the environment in which these T cells ... Moreover, the results of adoptive cell transfer are more positive when patients' own T cells are used. These findings show that ... This paper discusses a method of providing such an environment called adoptive cell transfer, as well as the elements that ...
  https://touroscholar.touro.edu/sjlcas/vol9/iss1/8/
*  Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem...
Bladder cancerCancer stem cellsImmunotherapyNatural killer cells. Background. Bladder cancer (BC) is the most common malignancy ... Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem- ... Cancer stem-like cells contribute to cisplatin resistance and progression in bladder cancer. Cancer Lett. 2012;322:70-7.View ... cell-based adoptive immunotherapy against chemoresistant bladder cancer stem-like cells (CSCs) in a pre-clinical relevant model ...
  https://0-bmcmedicine-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/s12916-016-0715-2
*  Safety, tumor trafficking and immunogenicity of chimeric antigen receptor (CAR)-T cells specific for TAG-72 in colorectal...
A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer. Clin Cancer Res. 2006;12:6106-15. ... Adoptive immunotherapy for cancer: harnessing the T cell response. Nat Rev Immunol. 2012;12:269-81.CrossRefPubMedGoogle Scholar ... Adoptive T cell transfer for cancer immunotherapy in the era of synthetic biology. Immunity. 2013;39:49-60.CrossRefPubMedGoogle ... 5.Mary Crowley Cancer CenterDallasUSA. *6.Laboratory of Tumor Immunology and Biology, Center for Cancer ResearchNational Cancer ...
  https://rd.springer.com/article/10.1186/s40425-017-0222-9
*  CAR T-Cell Immunotherapy: The 2018 Advance of the Year | Cancer.Net
What is this innovative cancer treatment? What are the risks and benefits? ... The 2018 Clinical Cancer Advances report of the American Society of Clinical Oncology has crowned an adoptive cell ... Here are 3 recent examples of the potential that adoptive cell immunotherapy brings to cancer treatment. ... Immunotherapy is a cancer treatment intended to make the body's immune system able to detect and destroy cancer cells. Immune ...
  https://www.cancer.net/blog/2018-01/car-t-cell-immunotherapy-2018-advance-year
*  Most recent papers with the keyword t cell repertoire | Read by QxMD
Adoptive cancer immunotherapy using DNA-demethylated T helper cells as antigen-presenting cells. ... www.readbyqxmd.com/read/29511178/adoptive-cancer-immunotherapy-using-dna-demethylated-t-helper-cells-as-antigen-presenting- ... In cancer cells, cancer/testis (CT) antigens become epigenetically derepressed through DNA demethylation and constitute ... attractive targets for cancer immunotherapy. Here we report that activated CD4+ T helper cells treated with a DNA-demethylating ...
  https://www.readbyqxmd.com/keyword/85410
*  Immunotherapy for Leukemia and Lymphoma | Cancer Support Community
New understanding of how the immune system works have led to a variety of exciting new results using immunotherapy for ... Adoptive Cell Therapies In adoptive T cell therapy, T cells are removed from a person with cancer, taken to a lab, and modified ... The type of immunotherapy used depends on the exact subtype of blood cancer being treated. Many immunotherapy treatment options ... Living With Cancer*Living With Cancer Topics*Cancer Diagnosis? What You Need to Know*Tips for Newly Diagnosed ...
  https://www.cancersupportcommunity.org/immunotherapy-leukemia-and-lymphoma
*  Frontiers | Neoantigen Targeting-Dawn of a New Era in Cancer Immunotherapy? | Immunology
Initially, neoantigens were not recognized as preferred targets for cancer immunotherapy due to their enormous diversity and ... we discuss the various subtypes of tumor antigens with a focus on neoantigens and their potential in cancer immunotherapy. We ... we discuss the various subtypes of tumor antigens with a focus on neoantigens and their potential in cancer immunotherapy. We ... of neoantigens in checkpoint inhibition has changed our view on the clinical potential of neoantigens in cancer immunotherapy. ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2017.01848/full
*  Emerging Role of Gamma Delta T-cells in Immunotherapies
Keywords: Chimeric antigen receptor T-cell therapy, gamma delta T-cells, γδ T-cells, adoptive T-cell therapies, cancer ... This service provides valuable insights across the global adoptive T-cell therapy landscape, while outlining the key unmet ... This edition of the Future Tech TOE focuses on the emerging role of gamma delta T-cell platforms in immunotherapy applications ... Keywords: Chimeric antigen receptor T-cell therapy, gamma delta T-cells, γδ T-cells, adoptive T-cell therapies, cancer ...
  http://www.frost.com/c/10107/sublib/display-report.do?id=D835-00-22-00-00&bdata=aHR0cDovL3d3dy5mcm9zdC5jb20vYy8xMDEwNy9zdWJsaWIvY2F0ZWdvcnktaW5kZXguZG8%2FYW5jaG9yPUQ4MzUtMDAtMjItMDAtMDAmY2F0ZWdvcnk9dGVjaG5vbG9neUB%2BQFRlY2hub2xvZ3kgUmVzZWFyY2hAfkAxNTA3NDM3ODM3NTgz
*  Targeting O-Acetyl-GD2 Ganglioside for Cancer Immunotherapy
... cancer immunology, transplantation immunology, immune pathology, immunodeficiency, autoimmune diseases, immune disorders, and ... 9. Adoptive Immunotherapy with O-Acetyl-GD2-Specific CARs. Chimeric antigen receptor (CAR) based adoptive immunotherapy is an ... Target selection is a key feature in cancer immunotherapy, a promising field in cancer research. In this respect, gangliosides ... and adoptive transfer of lymphocytes, genetically engineered to acquire tumor cell specificity. Immunotherapies of cancers ...
  https://www.hindawi.com/journals/jir/2017/5604891/