*  Protocadherin beta-8
... each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. ... Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.. 10716726. 2000. Large exons encoding ... These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown ... A striking organization of a large family of human neural cadherin-like cell adhesion genes.. ...
  https://pharos.nih.gov/idg/targets/Q9UN66
*  Cell adhesion receptors in C. elegans | Journal of Cell Science
Cadherins. Cadherins are calcium-dependent, homophilic, cell-cell adhesion receptors that regulate morphogenesis, pattern ... Two cadherin genes have been functionally characterized: hmr-1 and cdh-3. hmr-1 encodes two isoforms: HMR-1A, which is crucial ... The remaining putative cadherins (CDH-5, CDH-7, CDH-8, CDH-9, CDH-10 and CDH-12) have not been characterized, and are probably ... Pettitt, J., Wood, W. B. and Plasterk, R. H. (1996). cdh-3, a gene encoding a member of the cadherin superfamily, functions in ...
  http://jcs.biologists.org/content/117/10/1867
*  A molecular mechanism directly linking E-cadherin adhesion to initiation of epithelial cell surface polarity | JCB
... cadherin in cells because of a decrease in the level of endogenous E-cadherin commensurate with the level of ectopic E-cadherin ... E-cadherin-tdRFP accumulates at cell-cell contacts, and AQP3-EGFP coaccumulates with E-cadherin-tdRFP. Some AQP5-EGFP is at the ... E-cadherin-tdRFP was generated from EGFP-tagged E-cadherin (Adams et al., 1998). Photoactivatable constructs were generated by ... Newly synthesized AQP3 localized with E-cadherin at initial cell-cell contacts. E-cadherin dynamics and the formation of ...
  http://jcb.rupress.org/content/178/2/323
*  Cdh1 - Cadherin-1 precursor - Rattus norvegicus (Rat) - Cdh1 gene & protein
They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the ... IPR002126. Cadherin. IPR015919. Cadherin-like. IPR020894. Cadherin_CS. IPR000233. Cadherin_cytoplasmic-dom. IPR014868. Cadherin ... IPR002126. Cadherin. IPR015919. Cadherin-like. IPR020894. Cadherin_CS. IPR000233. Cadherin_cytoplasmic-dom. IPR014868. Cadherin ... PF00028. Cadherin. 5 hits. PF01049. Cadherin_C. 1 hit. PF08758. Cadherin_pro. 1 hit. ...
  http://www.uniprot.org/uniprot/Q9R0T4
*  TumorPortal
... each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. ... These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown ...
  http://www.tumorportal.org/view?geneSymbol=PCDHB9
*  Cdc6 expression represses E-cadherin transcription and activates adjacent replication origins. | Sigma-Aldrich
E-cadherin (CDH1) loss occurs frequently in carcinogenesis, contributing to invasion and metastasis. We observed that mouse and ... These data demonstrate that Cdc6 acts as a molecular switch at the E-cadherin locus, linking transcriptional repression to ... Cdc6 expression represses E-cadherin transcription and activates adjacent replication origins.. [Maria Sideridou, Roubini ... in various types of human cancer revealed a strong correlation between increased Cdc6 expression and reduced E-cadherin levels ...
  https://www.sigmaaldrich.com/catalog/papers/22201124
*  Wingless signaling modulates cadherin-mediated cell adhesion in Drosophila imaginal disc cells | Journal of Cell Science
To restore E-cadherin-mediated cell adhesion, cl-8 cells were transfected with a cDNA encoding mouse E-cadherin under control ... 4A), Arm co-fractionated with E-cadherin, indicating that the majority of Arm was complexed with E-cadherin and that the pool ... Thus, despite the presence of E-cadherin, a significant amount of Arm and α-catenin was not bound to E-cadherin upon activation ... Addition of Cu2+ resulted in an approximately eightfold increase in E-cadherin levels (Fig. 1A). Expression of E-cadherin ...
  http://jcs.biologists.org/content/119/12/2425
*  E-cadherin Immunohistochemistry Stain and Acute Erythroid Leukemia, the Emerging Story | OMICS International
E-Cadherin is calcium-dependent cell adhesion molecule encoded by CDH1 gene at chromosome 16q22.1. Ecadherin regulates cell- ... E-cadherin. E-cadherin (epithelial cadherin) is a polypeptide protein belongs to cadherins family whose primary function is to ... E-cadherin was moderately positive (≈ 40%) in immature erythroid precursors. E-cadherin stain is a useful marker that more ... E-cadherin is encoded by CDH1 gene which is located on the long (q) arm of chromosome 16 at position 22.1. [3] It is mainly ...
  https://www.omicsonline.org/open-access/ecadherin-immunohistochemistry-stain-and-acute-erythroid-leukemia-theemerging-story-2157-7099-1000352.php?aid=59564
*  BioE PhD Defense Presentation- Chimdimnma Esimai | BioE Graduate Program
Cadherin proteins mediate cell-cell adhesion in a calcium-dependent manner. The functional roles for cadherin proteins early in ... underscore the importance of cadherin proteins. Quantitative assessment of cadherin interaction structure, force, and ... The goal of this thesis was to engineer adhesive surfaces that support cadherin-based adhesion as a model system to analyze ... Adhesive force measurements promise to meet this challenge of elucidating how cadherin complex assembly and function coheres in ...
  http://www.bioengineering.gatech.edu/bioe-phd-defense-presentation-chimdimnma-esimai
*  British Library EThOS: The molecular mechanism of cadherin-mediated adhesion
My work examines the role of a conserved tryptophan residue, Trp2, in the adhesive domain of cadherins that has been shown to ... Our results thus define the mechanism of cadherin adhesion as a dynamic balance between the conflicting tendencies of Trp2 to ... Structural studies have shown Trp2 to be integrated into its own cadherin domain, integrated into the domain an opposing ... Using conformation specific antibodies I show that Trp2 integrates into the domain fold of its own cadherin molecule in ...
  http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.603783
*  Catenins as mediators of the cytoplasmic functions of cadherins | Journal of Cell Science
The catenins are polypeptides that bind to the conserved cytoplasmic tail of cadherins and are required for cadherin function. ... Catenins as mediators of the cytoplasmic functions of cadherins Message Subject (Your Name) has sent you a message from Journal ... α-Catenin is related to vinculin and seems to be required for the interaction of cadherins with the actin cytoskeleton. β- ... The catenins may be involved in the regulation of cadherin function during tissue morphogenesis and tumorigenesis. ...
  http://jcs.biologists.org/content/1993/Supplement_17/155
*  CDH17 - Wikipedia
Cadherin-17 is a protein that in humans is encoded by the CDH17 gene. This gene is a member of the cadherin superfamily, genes ... 2004). "Ksp-cadherin is a functional cell-cell adhesion molecule related to LI-cadherin". Exp. Cell Res. 294 (2): 345-55. doi: ... "Entrez Gene: CDH17 cadherin 17, LI cadherin (liver-intestine)". Gessner R, Tauber R (2001). "Intestinal cell adhesion molecules ... The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane ...
  https://en.wikipedia.org/wiki/CDH17
*  CDH4 - Wikipedia
Cadherin-4 is a protein that in humans is encoded by the CDH4 gene. This gene is a classical cadherin from the cadherin ... "Entrez Gene: CDH4 cadherin 4, type 1, R-cadherin (retinal)". Brady-Kalnay SM, Mourton T, Nixon JP, Pietz GE, Kinch M, Chen H, ... Kools P, Vanhalst K, van Roy F (Oct 1999). "Assignment of cadherin-4 (R-cadherin, CDH4) to human chromosome band 20q13.3". ... Suzuki S, Sano K, Tanihara H (1991). "Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue". ...
  https://en.wikipedia.org/wiki/CDH4
*  What are Cadherins?
Cadherins are a group of proteins that help cells stick together. They are the main components of certain types of junctions ... Classical cadherins include E-cadherin, N-cadherin, P-cadherin and N-cadherin 2. They all have a similar structure, with five ... Cadherin structure. Cadherins are named for calcium dependent adhesion. The external domain of a cadherin molecule - the part ... Cadherins' role in cancer. E-cadherin, a member of the cadherin family, has a very important role in organizing the epithelium ...
  https://www.news-medical.net/health/What-are-Cadherins.aspx
*  E-Cadherin | SpringerLink
Epithelial cadherin; Uvomorulin E-cadherin, a 120 kDa molecule, is a prototypical member of the classical cadherin family of ... Thus, E-cadherin and other members of the cadherin family play a crucial role in establishing and maintaining the integrity of ... E-cadherin, a 120 kDa molecule, is a prototypical member of the classical cadherin family of single-pass transmembrane proteins ... E-cadherin is the main adhesion molecule of the adherens junctions of epithelial cells, and via catenins it is linked to the ...
  https://link.springer.com/referenceworkentry/10.1007/978-3-642-27841-9_1777-2
*  Cadherin - Wikipedia
... cadherin 9, type 2 (T1-cadherin) CDH10 - cadherin 10, type 2 (T2-cadherin) CDH4 - R-cadherin (retinal) CDH5 - VE-cadherin ( ... N-cadherins are found in neurons CDH12 - cadherin 12, type 2 (N-cadherin 2) CDH3 - P-cadherin (placental): P-cadherins are ... cadherin 7, type 2 CDH8 - cadherin 8, type 2 CDH11 - OB-cadherin (osteoblast) CDH13 - T-cadherin - H-cadherin (heart) CDH15 - M ... KSP-cadherin CDH17 - LI cadherin (liver-intestine) CDH18 - cadherin 18, type 2 CDH19 - cadherin 19, type 2 CDH20 - cadherin 20 ...
  https://en.wikipedia.org/wiki/Cadherin
*  T-cadherin - Wikipedia
T-cadherin also known as cadherin 13, H-cadherin (heart) (CDH13) is a unique member of cadherin superfamily because it lacks ... T-cadherin expression results in LDL-induced migration of T-cadherin expressing cells compared to control. It is likely that T- ... T-cadherin expression was found to be altered in tumor vessels: in Lewis carcinoma lung metastasis the expression of T-cadherin ... T-cadherin is a GPI-anchored member of cadherin superfamily, which lacks a direct contact with cytoskeleton and therefore is ...
  https://en.wikipedia.org/wiki/T-cadherin
*  VE-cadherin - Wikipedia
VE-cadherin is a classical cadherin from the cadherin superfamily and the gene is located in a six-cadherin cluster in a region ... Cadherin 5, type 2 or VE-cadherin (vascular endothelial cadherin) also known as CD144 (Cluster of Differentiation 144), is a ... "Functional properties of human vascular endothelial cadherin (7B4/cadherin-5), an endothelium-specific cadherin". Arterioscler ... VE-cadherin is indispensable for proper vascular development - there have been two transgenic mouse models of VE-cadherin ...
  https://en.wikipedia.org/wiki/VE-cadherin
*  Cadherin cytoplasmic region - Wikipedia
In molecular biology, the cadherin cytoplasmic region is a conserved region found at the C-terminus of cadherin proteins. A key ... Nagafuchi A, Takeichi M (December 1988). "Cell binding function of E-cadherin is regulated by the cytoplasmic domain". EMBO J. ... Yap AS, Niessen CM, Gumbiner BM (May 1998). "The juxtamembrane region of the cadherin cytoplasmic tail supports lateral ... of the cadherin. This region induces clustering and also binds to the protein catenin (p120ctn). The cytoplasmic region is ...
  https://en.wikipedia.org/wiki/Cadherin_cytoplasmic_region
*  Cadherin-16 (IPR030721) | InterPro | EMBL-EBI
Cadherins are transmembrane proteins that mediate cell-cell adhesion in animals [PMID: 22833291]. Cadherin-16 (CDH16) or kidney ... CDH16/Ksp-cadherin is expressed in the developing thyroid gland and is strongly down-regulated in thyroid carcinomas.. ... Expression of Ksp-cadherin during kidney development and in renal cell carcinoma.. Br. J. Cancer 92 2010-7 2005 ... CDH16 colocalises with CDH1/E-cadherin on the basolateral plasma membrane of thyrocytes, and might play a role during thyroid ...
  http://www.ebi.ac.uk/interpro/entry/IPR030721
*  Fat atypical cadherin 3 - Wikipedia
FAT atypical cadherin 3 is a protein that in humans is encoded by the FAT3 gene. ENSG00000282908 GRCh38: Ensembl release 89: ... Mitsui, K; Nakajima, D; Ohara, O; Nakayama, M (2002). "Mammalian fat3: A large protein that contains multiple cadherin and EGF- ... FAT atypical cadherin 3". Retrieved 2014-09-11. Berndt, J. D.; Aoyagi, A; Yang, P; Anastas, J. N.; Tang, L; Moon, R. T. (2011 ...
  https://en.wikipedia.org/wiki/Fat_atypical_cadherin_3
*  Re: cadherins
... From:. DDittus787@aol.com. --part1_c5.f6ea0ca.27fcf0de_boundary Content-Type: text/plain; charset='US-ASCII' ... We use Zymeds cadherins, fresh slides (a must) protease 1 4-8 min, 32 min ,BR,incubation, Hope this helps. Dana,/FONT,,/HTML ... Content-Transfer-Encoding: 7bit We use Zymeds cadherins, fresh slides (a must) protease 1 4-8 min, 32 min incubation, Hope this ...
  http://www.histosearch.com/histonet/Apr01/Re.cadherins.html
*  Cadherin related family member 3 - Wikipedia
Cadherin related family member 3 (CDHR3), also known as CDH28 or its abbreviation CDHR3, is a protein that in humans is encoded ... Bochkov YA, Watters K, Ashraf S, Griggs TF, Devries MK, Jackson DJ, Palmenberg AC, Gern JE (2015). "Cadherin-related family ... it is believed to be related the function of similar cadherins which function in cell adhesion and cell-to-cell signaling. A ... Cadherin related family member 3". Retrieved 2017-09-05. "Tissue expression of CDHR3 - Summary - The Human Protein Atlas". www. ...
  https://en.wikipedia.org/wiki/Cadherin_related_family_member_3
*  Anti-pan Cadherin antibody (ab74635) | Abcam
Rabbit polyclonal pan Cadherin antibody validated for IHC and tested in Human, Mouse, Rat, Chk, Cow, Dog, Xl and Mk. Immunogen ... This antibody recognizes members of the Cadherin family of proteins including E-cadherin, N-cadherin, P-cadherin and R-cadherin ... In adhesion junctions cadherins are bound to beta and gamma catenins which in turn bind to alpha catenin, an actin binding ... Cadherins are expressed in a tissue specific manner and and are required for assembly of cells into solid tissue. Individual ...
  http://www.abcam.com/pan-cadherin-antibody-ab74635.html
*  Cadherin-catenin complex in learning and memory - Wikipedia
Dimerized cadherins readily bind to their presynaptic cadherin partners. Inhibition of N-cadherin binding via blocking ... N-cadherins are transmembrane proteins expressed in the majority of CNS synapses. N-cadherins are most commonly expressed on ... At basal levels of synaptic activity, N-cadherins are largely monomers and are thus weakly adhesive to cadherins located in the ... P120 ctn proteins are thought to either inhibit endocytosis of neural cadherins, or act at the cell surface to control cadherin ...
  https://en.wikipedia.org/wiki/Cadherin%E2%80%93catenin_complex_in_learning_and_memory