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*  NFE2L1 - Wikipedia
"Transcription factor NF-E2-related factor 1 impairs glucose metabolism in mice". Genes to Cells. 19 (8): 650-65. doi:10.1111/ ... "Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif". Oncogene. 14 ( ... Zhang Y, Lucocq JM, Hayes JD (Mar 2009). "The Nrf1 CNC/bZIP protein is a nuclear envelope-bound transcription factor that is ... an NF-E2-related transcription factor, by genetic selection in yeast". Proceedings of the National Academy of Sciences of the ...
  https://en.wikipedia.org/wiki/NFE2L1
*  Expression of Glutathione Peroxidase and Glutathione Reductase and Level of Free Radical Processes under Toxic Hepatitis in Rats
NF-E2-related factor 2) and Nrf1 are transcription factors that bind to AREs and activate these genes. Inactive Nrf2 is ... In the nucleus, Nrf2 activates genes through AREs by interacting with transcription factors in the bZIP family, including CREB ... Y. Huang, W. Li, and A. N. T. Kong, "Anti-oxidative stress regulator NF-E2-related factor 2 mediates the adaptive induction of ... D. Bloom, S. Dhakshinamoorthy, W. Wang, C. M. Celli, and A. K. Jaiswal, "Role of NF-E2 related factors in oxidative stress," in ...
  https://www.hindawi.com/journals/jt/2013/870628/
*  MAFK - Wikipedia
"The ubiquitous subunit of erythroid transcription factor NF-E2 is a small basic-leucine zipper protein related to the v-maf ... MafK is one of the small Maf proteins, which are basic region and basic leucine zipper (bZIP)-type transcription factors. The ... MafK was also identified as p18 NF-E2, a component of NF-E2 complex binding to a specific motif (NF-E2) in the regulatory ... Transcription factor MafK is a bZip Maf transcription factor protein that in humans is encoded by the MAFK gene. ...
  https://en.wikipedia.org/wiki/MAFK
*  Mechanisms of Nrf2/Keap1-Dependent Phase II Cytoprotective and Detoxifying Gene Expression and Potential Cellular Targets of...
... and review articles dealing with the cellular and molecular mechanisms of oxidative stress in the nervous system and related ... including NF-E2-related factor 2 (Nrf2) [8]. Nrf2 is a member of cap"n"collar (CNC) family of basic leucine zipper (bZIP) ... transcription factor that allows cells to mediate a collective activation of phase II cytoprotective and detoxifying enzymes [9 ... is activated in response to growth factors and external oxidants such as [32]. Because GSK3β activity is negatively regulated ...
  https://www.hindawi.com/journals/omcl/2013/839409/
*  MAFG - Wikipedia
Shivdasani RA, Rosenblatt MF, Zucker-Franklin D, Jackson CW, Hunt P, Saris CJ, Orkin SH (Jun 1995). "Transcription factor NF-E2 ... MafG is one of the small Maf proteins, which are basic region and basic leucine zipper (bZIP)-type transcription factors. The ... and its related sequences. Structural analyses have demonstrated that the basic region of a Maf factor recognizes the flanking ... Transcription factor MafG is a bZip Maf transcription factor protein that in humans is encoded by the MAFG gene. ...
  https://en.wikipedia.org/wiki/MAFG
*  Small Maf - Wikipedia
Hirotsu, Y (2012). "NF-E2-related factor 1 (Nrf1) serves as a novel regulator of hepatic lipid metabolism through regulation of ... sMafs form homodimers by themselves and heterodimers with other specific bZIP transcription factors, such as transcription ... Shivdasani, RA (1995). "Transcription factor NF-E2 is required for platelet formation independent of the actions of ... Toki, T (1997). "Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif ...
  https://en.wikipedia.org/wiki/Small_Maf
*  Novel Hematopoietic Target Genes in the NRF2-Mediated Transcriptional Pathway
... and review articles dealing with the cellular and molecular mechanisms of oxidative stress in the nervous system and related ... "Heme regulates the dynamic exchange of Bach1 and NF-E2-related factors in the Maf transcription factor network," Proceedings of ... Studies suggest that BACH1 heterodimerizes the same small Maf and other bZIP proteins as NRF2 and NFE2, indicating an ... R. A. Shivdasani and S. H. Orkin, "Erythropoiesis and globin gene expression in mice lacking the transcription factor NF-E2," ...
  https://www.hindawi.com/journals/omcl/2013/120305/
*  NFE2L2 - Wikipedia
"Chromosomal localization of the human NF-E2 family of bZIP transcription factors by fluorescence in situ hybridization". Human ... "Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the ... NFE2L2 and other genes, such as NFE2, NFE2L1 and NFE2L3, encode basic leucine zipper (bZIP) transcription factors. They share ... "NF-E2-related factor 2 promotes atherosclerosis by effects on plasma lipoproteins and cholesterol transport that overshadow ...
  https://en.wikipedia.org/wiki/NFE2L2
*  MafG Sumoylation Is Required for Active Transcriptional Repression
Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins. Nature 367:568-572. [PubMed] ... including transcription, mitosis, and nuclear/cytoplasmic transport (35). An increasing number of transcription factors have ... Maf nuclear oncoprotein recognizes sequences related to an AP-1 site and forms heterodimers with both Fos and Jun. Mol. Cell. ... Two new members of the maf oncogene family, mafK and mafF, encode nuclear b-Zip proteins lacking putative trans-activator ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC1489127/?lang=en-ca
*  BACH2 - Wikipedia
... family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 ... "A combinatorial code for gene expression generated by transcription factor Bach2 and MAZR (MAZ-related factor) through the BTB/ ... It contains a BTB/POZ domain at its N-terminus which forms a disulphide-linked dimer and a bZip_Maf domain at the C-terminus. ... Vieira SA, Deininger MW, Sorour A, Sinclair P, Foroni L, Goldman JM, Melo JV (Dec 2001). "Transcription factor BACH2 is ...
  https://en.wikipedia.org/wiki/BACH2
*  BACH1 - Wikipedia
... family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 ... "A combinatorial code for gene expression generated by transcription factor Bach2 and MAZR (MAZ-related factor) through the BTB/ ... The C-terminus of the protein is a leucine zipper of the bzip_maf family. When this protein forms a heterodimer with MafK, it ... This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family ( ...
  https://en.wikipedia.org/wiki/BACH1
*  High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated...
... transcription factor family, has been implicated as a key molecule involved in antioxidant-responsive element (ARE)-mediated ... Two factors important in its detoxification are UDP-glucuronosyltransferase (UDP-GT), an ARE-regulated phase-II drug- ... Targeting the NF-E2-Related Factor 2 Pathway: a Novel Strategy for Traumatic Brain Injury. *Li Zhang, Handong Wang ... Nrf2, which belongs to the basic leucine zipper (bZip) transcription factor family, has been implicated as a key molecule ...
  https://www.semanticscholar.org/paper/High-sensitivity-of-Nrf2-knockout-mice-to-with-of-Enomoto-Itoh/d30a88208b063b8239b854f66cedf1c4e06da183
*  Oleanolic acid attenuates TGF-β1-induced epithelial-mesenchymal transition in NRK-52E cells | BMC Complementary and Alternative...
Oleanolic acid (OA), an activator of NF-E2-related factor 2 (Nrf2), is reported to attenuate renal fibrosis in mice with ... Oleanolic acid (OA), an activator of NF-E2-related factor 2 (Nrf2), is reported to attenuate renal fibrosis in mice with ... Nrf2 is a basic leucine-zipper (bZip) transcription factor that protects cells and tissues from oxidative and electrophilic ... Among many fibrogenic factors regulating renal fibrotic process, transforming growth factor-β1 (TGF-β1) is the key mediators ...
  https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-018-2265-y
*  IJMS | Free Full-Text | Emerging Roles for Intersectin (ITSN) in Regulating Signaling and Disease Pathways
Frataxin Deficiency Leads to Reduced Expression and Impaired Translocation of NF-E2-Related Factor (Nrf2) in Cultured Motor ... Plant bZIP Transcription Factors Responsive to Pathogens: A Review. Previous Article in Special Issue. Characterization and ...
  http://www.mdpi.com/1422-0067/14/4/7829
*  NFE2 - Transcription factor NF-E2 45 kDa subunit - Homo sapiens (Human) - NFE2 gene & protein
Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin ... Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C ... Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. ... sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. ...
  http://www.uniprot.org/uniprot/Q16621
*  Identification of Bach2 as a B‐cell‐specific partner for small Maf proteins that negatively regulate the immunoglobulin heavy...
Chan JY, Han X‐L and Kan YW (1993) Cloning of Nrf1, an NFE2related transcription factor, by genetic selection in yeast. Proc ... transcription factor. Introduction. Maf family transcription factors possess a conserved basic‐region leucine zipper (bZip) ... Moi P, Chan K, Asunis I, Cao A and Kan YW (1994) Isolation of NFE2related factor 2 (Nrf2), an NFE2‐like basic leucine zipper ... specific transcription factor NFE2 is a heterodimer formed between the erythroid‐ and megakaryocyte‐specific bZip protein, p45 ...
  http://emboj.embopress.org/content/17/19/5734
*  稲葉 俊哉(原爆放射線医科学研究所)
Transcription factor NF-E2 is essential for the polyploidization of a human megakaryoblastic cell line, Meg-J., Biochem. ... TEF, an antiapoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by down- ... Cell transformation mediated by homodimeric E2A-HLF transcription factors., Mol. Cell. Biology, 17巻, pp.1417-pp.1424, 19970401 ... TEF, an anti-apoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by ...
  http://seeds.office.hiroshima-u.ac.jp/profile/ja.1e597bcbcf537f05520e17560c007669.html
*  Linking ER Stress to Autophagy: Potential Implications for Cancer Therapy
PERK also phosphorylates the Nuclear factor-E2-related factor 2 (Nrf2) [30]. Nrf2 is a bZIP Cap 'n Collar transcription factor ... Processed ATF6 moves to the nucleus where it forms active homodimers or dimerizes with other bZIP transcription factors like NF ... bZIP) transcription factor XBP1s that regulates the transcription of several genes involved in ER quality control mechanisms, ... a member of the bZIP family of transcription factors [29]. The PERK-eIF2. -ATF4 axis regulates the expression of genes involved ...
  https://www.hindawi.com/journals/ijcb/2010/930509/
*  Low and High Dose UVB Regulation of Transcription Factor NF-E2-Related Factor 2 | Cancer Research
Nrf2, a member of the NF-E2 family of transcription factors, is not essential for murine erythropoiesis, growth, and ... bZIP; ref. 13). Nrf2−/− mice are viable and live to adulthood, showing that Nrf2 is not required for erythropoiesis, ... Low and High Dose UVB Regulation of Transcription Factor NF-E2-Related Factor 2. Sankaranarayanan Kannan and Anil K. Jaiswal ... Transcription factor NF-E2-related factor 2 (Nrf2) regulates antioxidant response element (ARE)-mediated expression and ...
  http://cancerres.aacrjournals.org/content/66/17/8421
*  MAFG - Transcription factor MafG - Homo sapiens (Human) - MAFG gene & protein
... such as NFE2, NFE2L1 and NFE2L2, and recruiting them to specific DNA-binding sites (PubMed:8932385, PubMed:9421508, PubMed: ... Transcription factor, component of erythroid-specific transcription factor NFE2L2 (PubMed:11154691). Activates globin gene ... Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NFE2L2 transcription factor (PubMed: ... IPR004827. bZIP. IPR004826. bZIP_Maf. IPR028551. MafG. IPR008917. TF_DNA-bd_sf. IPR024874. Transciption_factor_Maf_fam. ...
  http://www.uniprot.org/uniprot/O15525
*  Curcumin Protects Human Keratinocytes against Inorganic Arsenite-Induced Acute Cytotoxicity through an NRF2-Dependent Mechanism
... and review articles dealing with the cellular and molecular mechanisms of oxidative stress in the nervous system and related ... collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible ... Nuclear factor erythroid 2-related factors (NRFs) are a family of transcription factors that regulate the cellular adaptive ... J. Y. Chan, M. Kwong, R. Lu et al., "Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in ...
  https://www.hindawi.com/journals/omcl/2013/412576/
*  NFE2L2 Gene - GeneCards | NF2L2 Protein | NF2L2 Antibody
Nuclear Factor, Erythroid 2 Like 2, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - ... Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the ... Transcription factors. Protein Domains for NFE2L2 Gene. Blocks:. * bZIP transcription factor, bZIP_1 ... nuclear factor,erythroid derived 2-like 2,Capncollar (CNC) family of transcription factor,NF-E2-like *NFE2L2 ...
  https://www.genecards.org/cgi-bin/carddisp.pl?gene=NFE2L2
*  NRF1 - Wikipedia
"Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif". Oncogene. 14 ( ... "Interaction of the CNC-bZIP factor TCF11/LCR-F1/Nrf1 with MafG: binding-site selection and regulation of transcription". ... structurally and functionally related transcription factors from humans and drosophila". J. Cell Sci. 113 (23): 4263-73. PMID ... key transcription factor for eukaryotic initiation factor-2 alpha is strongly homologous to developmental transcription factors ...
  https://en.wikipedia.org/wiki/NRF1
*  С ?? ҩ ??.??Ϣ?? .11202501??11203000
11202592:The bZIP Transcription Factor ATFx Binds Human T-C. *11202593:The 5'-Terminal Region of the Aichi Virus Genome E ... 11202674:Role of Tumor Necrosis Factor-Related Apoptosis-In. *11202675:Murine Coronavirus Evolution In Vivo: Functional C ... 11202717:Factors Required for the Uridylylation of the Foot. *11202718:Attenuation of Equine Influenza Viruses through Tr ... 11202823:Respiratory Syncytial Virus Influences NF-B-Depend. *11202824:Activation of the N-Ras CPI3K CAkt-mTOR Pathway by H ...
  http://www.100md.com/index/other/byinfono/022/406.htm
*  Therapeutic Approach to Neurodegenerative Diseases by Medical Gases: Focusing on Redox Signaling and Related Antioxidant Enzymes
... and review articles dealing with the cellular and molecular mechanisms of oxidative stress in the nervous system and related ... Their expression is regulated by several transcription factors and/or cofactors like nuclear factor-erythroid 2 (NF-E2) related ... Nrf2 belongs to the cap'n'collar (CNC) family of basic region-leucine zipper (bZip)-type transcription factors [10]. NF-E2 is a ... Nuclear factor-erythroid 2 (NF-E2) related factor 2 (Nrf2) is an important transcription factor and is recognized as a major ...
  https://www.hindawi.com/journals/omcl/2012/324256/