*  Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM. | MRC Mitochondrial Biology Unit
Mitochondrial Proton-Translocating ATPases, Models, Molecular, Protein Conformation, Protein Folding. Abstract. Adenosine ... is synthesized in eukaryotic cells primarily by the mitochondrial ATP synthase. ATP synthases operate by a rotary catalytic ... We report here single particle electron cryomicroscopy (cryo-EM) analysis of the bovine mitochondrial ATP synthase. Combining ... Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM.. ...
  http://www.mrc-mbu.cam.ac.uk/publications/2468/structure-and-conformational-states-bovine-mitochondrial-atp-synthase-cryo-em
*  The structure of bovine F1-ATPase complexed with the peptide antibiotic efrapeptin. | MRC Mitochondrial Biology Unit
Proton-Translocating ATPases. Abstract. In the previously determined structure of mitochondrial F1-ATPase determined with ... 15 amino acids that inhibit both ATP synthesis and hydrolysis by binding to the F1 catalytic domain of F1F0-ATP synthase. In ... The structure of bovine F1-ATPase complexed with the peptide antibiotic efrapeptin.. ... The structure of bovine F1-ATPase complexed with the peptide antibiotic efrapeptin.. ...
  http://www.mrc-mbu.cam.ac.uk/publications/2687/structure-bovine-f1-atpase-complexed-peptide-antibiotic-efrapeptin
*  ATP synthase - Wikipedia
Proton and Sodium translocating F-type, V-type and A-type ATPases in OPM database The Nobel Prize in Chemistry 1997 to Paul D. ... "Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM". eLife. 4: e10180. doi:10.7554/eLife. ... However, whereas the F-ATP synthase generates ATP by utilising a proton gradient, the V-ATPase generates a proton gradient at ... The consumption of ATP by ATP-synthase pumps proton cations into the matrix. The evolution of ATP synthase is thought to have ...
  https://en.wikipedia.org/wiki/ATP_synthase
*  Structure and mechanism of the ATP synthase membrane motor inferred from quantitative integrative modeling | JGP
S2 shows a cryo-EM map of the subunit a-c-ring complex from the bovine mitochondrial ATP synthase. Fig. S3 shows alignment of ... The cytoplasmic loops of subunit a of Escherichia coli ATP synthase may participate in the proton translocating mechanism. J. ... The structure of bovine F1-ATPase in complex with its regulatory protein IF1. Nat. Struct. Biol. 10:744-750. doi:10.1038/nsb966 ... Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM. eLife. 4:e10180. doi:10.7554/eLife. ...
  http://jgp.rupress.org/content/early/2016/11/04/jgp.201611679
*  Further Insight into Mechanism of Action of Clodronate: Inhibition of Mitochondrial ADP/ATP Translocase by a Nonhydrolyzable,...
ATP synthase (F1Fo-ATPase), and ADP/ATP translocase. AppCCl2p is shown to inhibit the ADP/ATP translocase in the mitochondrial ... which is translocated by ANT (Watanabe et al., 1985). ATP and ADP are known to inhibit PT pore opening (Halestrap et al., 1997 ... A mixed rat bone cell population was cultured on clodronate-coated or control bovine bone slices as described previously (Boyde ... Moreover, if the translocation of bisphosphonate would occur in the protonated form, the high proton gradient across the basal ...
  http://molpharm.aspetjournals.org/content/61/5/1255
*  Oxidative phosphorylation - Wikipedia
As protons cross the membrane through the channel in the base of ATP synthase, the FO proton-driven motor rotates. Rotation ... "Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex". Science. 281 (5373): 64-71. Bibcode:1998Sci ... Becher B, Müller V (1994). "Delta mu Na+ drives the synthesis of ATP via an delta mu Na(+)-translocating F1F0-ATP synthase in ... "The cellular biology of proton-motive force generation by V-ATPases". J. Exp. Biol. 203 (Pt 1): 89-95. PMID 10600677. ...
  https://en.wikipedia.org/wiki/Oxidative_phosphorylation
*  Hyperlipid: 2013
This reduces uncoupling because there is a much lower voltage pushing protons back in to the mitochondrial matrix. This means ... Life (03) ATP synthase (1) * Life (04) On the bench top (1) ... We can now translocate GLUT4s to the cell surface and start to ... The fluorescence rises with inner mitochondrial membrane potential, delta psi. Antimycin A blocks ATPase so hyperpolarises the ... BSA (bovine serum albumin) eliminates the uncoupling as it "hoovers-up" all available FFAs.. Does this uncoupling happen in ...
  http://high-fat-nutrition.blogspot.com.br/2013/
*  http://ufdc.ufl.edu/UFE0042762/00001
The F 1 F o ATPase is also important for maintenance of the proton motive force (PMF) Assembly of the F 1 F o ATP synthase has ... the F 1 F o ATP S ynthase Acid tolerance has been largely attributed to the activity of the proton translocating F 1 F o ATPase ... P rotein concentrat ion s were determined by BCA assay with a 1/500 dilution of membranes A 1 m g/ml s tock solution of bovine ... Jia, L., Dienhart, M., Schramp, M., McCauley, M., Hell, K. & Stuart, R. A. (2003) Yeast Oxa1 interacts with mitoc hondrial ...
  http://ufdc.ufl.edu/UFE0042762/00001
*  M5 Receptors
With pH Together, it models the traveling push for ATP synthase, and for cytosolic Ca2+ to enter the matrix [9]. Average ... the extrusion of Ca2+ generates huge amounts of protons that are sent to mitochondrial matrix leading to pH lower [13]. AR-42 ... The crystal structure of the bovine enzyme has been determined previously (8), showing that the four redox-active centers of ... Plasma membrane layer California2+-ATPase (PMCA) by extruding California2+ outdoors the cell,. Posted by techtasys , M5 ...
  http://www.techtasys.com/category/m5-receptors/
*  Fosforylacja oksydacyjna - Wikipedia, wolna encyklopedia
a b Becher B, Müller V. Delta mu Na+ drives the synthesis of ATP via a delta mu Na(+)-translocating F1F0-ATP synthase in ... a b c d Schultz B, Chan S. Structures and proton-pumping strategies of mitochondrial respiratory enzymes. „Annu Rev Biophys ... ATP synthase complex from bovine heart mitochondria: the oligomycin sensitivity conferring protein is essential for ... Nelson N, Perzov N, Cohen A, Hagai K, Padler V, Nelson H. The cellular biology of proton-motive force generation by V-ATPases ...
  https://pl.wikipedia.org/wiki/Fosforylacja_oksydacyjna
*  Proteomic changes in a childhood acute lymphoblastic leukemia cell line during the adaptation to vincristine | Boletín Médico...
Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient ... The B-lineage pediatric ALL cell line CCRF-SB (ATCC CCL-120) was grown in RPMI-1640 with 10% (v/v) fetal bovine serum, 100 U/ml ... Sarcoplasmic/ endoplasmic reticulum calcium ATPase 2 P16615 Cation transporter, ion channel Homeostatic process This magnesium- ... 40 Calcium is translocated from the cytosol to the sarcoplasmic reticulum lumen by the AT2A2 protein (assigned to the ...
  http://www.elsevier.es/es-revista-boletin-medico-del-hospital-infantil-401-articulo-proteomic-changes-in-childhood-acute-S1665114617300473
*  Adenosine triphosphate - Wikipedia
Flow of protons down this potential gradient - that is, from the intermembrane space to the matrix - yields ATP by ATP synthase ... which is translocated to the mitochondrial matrix. Another malate dehydrogenase-catalyzed reaction occurs in the opposite ... Å resolution of F1-ATPase from bovine heart mitochondria". Nature. 370 (6491): 621-628. doi:10.1038/370621a0. PMID 8065448. ... ATP synthase then ensues exactly as in oxidative phosphorylation. Some of the ATP produced in the chloroplasts is consumed in ...
  https://en.wikipedia.org/wiki/Adenosine_triphosphate
*  Adenosine triphosphate - Wikipedia
Flow of protons down this potential gradient - that is, from the intermembrane space to the matrix - yields ATP by ATP synthase ... Abrahams, J.; Leslie, A.; Lutter, R.; Walker, J. (1994). "Structure at 2.8 Å resolution of F1-ATPase from bovine heart ... which is translocated to the mitochondrial matrix. Another malate dehydrogenase-catalyzed reaction occurs in the opposite ... ATP synthase then ensues exactly as in oxidative phosphorylation.[21] Some of the ATP produced in the chloroplasts is consumed ...
  https://en.m.wikipedia.org/wiki/Adenosine_triphosphate
*  Complementation of the Fo c Subunit of Escherichia coli with That of Streptococcus mutans and Properties of the Hybrid FoF1 ATP...
In vivo evidence for the role of the epsilon subunit as an inhibitor of the proton-translocating ATPase of Escherichia coli. J ... coli ATP synthase. We could not express functional S. mutans ATP synthase from the cloned ATP operon (see Fig. S1 and S2 in the ... It is localized in bacterial plasma membranes and mitochondrial inner and chloroplast thylakoid membranes. F1 has three ... using bovine serum albumin (fraction V; Sigma) as a standard. ... ATP synthase (H+-ATPase): results by combined biochemical and ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC3807490/?lang=en-ca
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... and activity of F0F1-ATPase. Energy status of RPTC is assessed by determining the intracellular ATP content. Mitochondrial ... MitGO-ATeam is a Förster resonance energy transfer (FRET) probe in which the ε subunit of the FoF1-ATP synthase is sandwiched ... dissipation of the proton motive force, membrane potential collapse and an increase in mitochondrial matrix volume (swelling) ... Upon binding of insulin to its receptor, vesicles containing GLUT4 translocate from the cytoplasm to the plasma membrane, ...
  https://www.jove.com/visualize/abstract/22028857/changes-cardiac-substrate-transporters-metabolic-proteins-mirror
*  Fosforilasi oksidatif - Wikipedia bahasa Indonesia, ensiklopedia bebas
a b Joshi S, Huang YG (1991). "ATP synthase complex from bovine heart mitochondria: the oligomycin sensitivity conferring ... "Hyperthyroidism stimulates mitochondrial proton leak and ATP turnover in rat hepatocytes but does not change the overall ... "Delta mu Na+ drives the synthesis of ATP via a delta mu Na(+)-translocating F1F0-ATP synthase in membrane vesicles of the ... Müller V (2004). "An exceptional variability in the motor of archaeal A1A0 ATPases: from multimeric to monomeric rotors ...
  https://id.wikipedia.org/wiki/Fosforilasi_oksidatif
*  Bcl-xL regulates mitochondrial energetics by stabilizing the inner membrane potential | JCB
Because the mitochondrial F1FO ATP synthase is an important control point for proton flux across the inner mitochondrial ... The structure of bovine F1-ATPase complexed with the antibiotic inhibitor aurovertin B. Proc. Natl. Acad. Sci. USA. 93:6913- ... Endogenous Bcl-xL in HeLa cells resides predominantly in the cytosol as a homodimer and translocates to mitochondria via its C- ... The mitochondrial F1FO ATP synthase synthesizes ATP in the mitochondrial matrix using cytosolic ADP and phosphate as substrates ...
  http://jcb.rupress.org/content/195/2/263.long
*  Publications | Paul Scherrer Institut (PSI)
The structure of bovine mitochondrial F1-ATPase ? an example of rotational catalysis? Leslie AGW, Abrahams JP, van Raaij M, ... ATP-induced conformational changes of the nucleotide-binding domain of Na,K-ATPase Hilge M, Siegal G, Vuister G, Güntert P, ... Evidence for proton shuffling in a thioredoxin-like protein during catalysis Narzi D, Siu SWI, Stirnimann CU, Grimshaw JPA, ... A Type IV Translocated Legionella Cysteine Phytase Counteracts Intracellular Growth Restriction by Phytate Weber Stephen, ...
  https://www.psi.ch/lbr/publications
*  Equilibrative Nucleoside Transporters
The obstructing remedy comprised of 5% regular donkey serum, 2% bovine serum albumin, and 0.5% Triton X-100 in PBS. In some ... Intracellular translocation of histatins can be inhibited by low temps (19) or pretreatment of cells with proton ionophores ... Treatment of cells with a spermidine synthase inhibitor increased spermidine uptake and Hst 5 killing whereas protonophores and ... 11). Comparison with amphipathic peptides that translocated across and disrupted liposome membranes showed that Hst 5 did PP121 ...
  http://www.ovarian-cancersymptoms.com/category/equilibrative-nucleoside-transporters/
*  Adenosine triphosphate - wikidoc
This produces a proton-motive force and this drives the ATP synthase, exactly as in oxidative phosphorylation.[20] Some of the ... Abrahams J, Leslie A, Lutter R, Walker J (1994). "Structure at 2.8 A resolution of F1-ATPase from bovine heart mitochondria". ... which is translocated to the mitochondrial matrix. Another malate dehydrogenase-catalyzed reaction occurs in the opposite ... In neutral solution, ATP is ionized and exists mostly as ATP4−, with a small proportion of ATP3−.[8] As ATP has several ...
  http://es.wikidoc.org/index.php/Adenosine_triphosphate
*  The world's most compressed sentence - Peter Horttanainen
FoF1-ATP synthase family of proteins convert the chemical energy in ATP to the electrochemical potential energy of a proton ... 1992 - Isolation of the first reported mitochondrial DNA helicase (from bovine brain)[21] ... those that translocate in a 5′-3′ direction along single-stranded DNA and those that operate with the opposite polarity. For ... including two domains that are structurally similar to the ATPase domain of the recombination protein RecA (Story and Steitz ...
  http://peterhorttanainen.com/the-worlds-most-compressed-sentence/
*  The ATP synthase is involved in generating mitochondrial cristae morphology. | MRC Mitochondrial Biology Unit
The inner membrane of the mitochondrion folds inwards, forming the cristae. This folding allows a greater amount of membrane to be packed into the mitochondrion. The data in this study demonstrate that subunits e and g of the mitochondrial ATP synthase are involved in generating mitochondrial cristae morphology. These two subunits are non-essential components of ATP synthase and are required for the dimerization and oligomerization of ATP synthase. Mitochondria of yeast cells deficient in either subunits e or g were found to have numerous digitations and onion-like structures that correspond to an uncontrolled biogenesis and/or folding of the inner mitochondrial membrane. The present data show that there is a link between dimerization of the mitochondrial ...
  http://www.mrc-mbu.cam.ac.uk/publications/2738/atp-synthase-involved-generating-mitochondrial-cristae-morphology
*  Plus it
In the past decade, ectopic ATP synthase has been shown to involve a variety of functions in lipid metabolism, immune recognition, and invasiveness of tumors (3, 6, 9, 16), regulation of intracellular pH (14, 30), differentiation (13), control of proliferation and cell death (3, 10, 15). Ectopic ATP synthase has been shown to localize on the cell membrane of different cancer cell types. Here, we show that the ATP synthase complex and ETC are localized on the membrane of lung cancer cells. In an attempt to shed light on the cellular processes affected by the action of this complex, and to provide further insights into the mechanistic action of the ATP synthase inhibitor citreoviridin, we show that the inhibition of ectopic ATP synthase is associated with the inhibition of lung cancer cell growth and the activation of UPR. By disrupting the ...
  http://cancerres.aacrjournals.org/content/72/18/4696
*  Phosphorylation of the F1Fo ATP Synthase β Subunit | Circulation Research
Preconditioning (PC) is a phenomenon by which physiological and pharmacological interventions protect the heart from damage during future ischemic episodes (for review see1). Mitochondria have long been implicated in this protective phenotype.2,3 In studying the link between PC and the mitochondria, our group observed phosphorylation of the F1Fo ATP synthase complex β subunit (ATPβ) in response to adenosine mediated PC.4 There have been several observations connecting modulation of the ATP synthase complex to PC, including its specific downregulation to preserve ATP pools during ischemia.5-7 The goal of the present work was to gain insight into the functional aspects of phosphorylation of ATPβ by mutation of the amino acid residues in a model system.. It is becoming increasingly clear that mitochondria participate in control by kinase cascades and protein phosphorylation (for reviews, see ...
  http://circres.ahajournals.org/content/106/3/504
*  Horizontal membrane-intrinsic α-helices in the stator a-subunit of an F-type ATP synthase. | MRC Mitochondrial Biology Unit
ATP, the universal energy currency of cells, is produced by F-type ATP synthases, which are ancient, membrane-bound nanomachines. F-type ATP synthases use the energy of a transmembrane electrochemical gradient to generate ATP by rotary catalysis. Protons moving across the membrane drive a rotor ring composed of 8-15 c-subunits. A central stalk transmits the rotation of the c-ring to the catalytic F1 head, where a series of conformational changes results in ATP synthesis. A key unresolved question in this fundamental process is how protons pass through the membrane to drive ATP production. Mitochondrial ATP synthases form V-shaped homodimers in cristae membranes. Here we report the structure of a native and active mitochondrial ...
  http://www.mrc-mbu.cam.ac.uk/publications/2697/horizontal-membrane-intrinsic-%CE%B1-helices-stator-subunit-f-type-atp-synthase
*  Mitochondrial Coupling Factor 6 Is Present on the Surface of Human Vascular Endothelial Cells and Is Released by Shear Stress |...
Mitochondrial ATP synthase consists of 3 domains, namely the extrinsic and intrinsic membrane domains, F1 and F0, respectively, joined by a stalk.1,2 Four subunits of the stalk were identified and designated as coupling factor 6 (CF6), oligomycin sensitivity conferral protein, and subunits b and d.3-5 Of these 4 subunits, CF6 was reported to be essentially required for energy transduction.6 We recently demonstrated that CF6 is an endogenous inhibitory peptide of prostacyclin synthesis in vascular endothelial cells.7 This novel function of CF6 was discovered from the investigation of the mechanism of the discrepancy of prostacyclin synthesis seen in spontaneously hypertensive rats: The level of circulating prostacyclin in spontaneously hypertensive rats was decreased compared with that in normotensive control Wistar Kyoto rats, although the generation activity of prostacyclin in aortic strips was higher in spontaneously hypertensive rats than ...
  http://circ.ahajournals.org/content/104/25/3132
*  AtpB recombinant protein standard for quantitation
quantification of AtpB, ATP synthase, AS03-030, Anti-AtpB, ATP Synthase, Beta subunit of ATP synthase polyclonal antibody, Arabidopsis thaliana chloroplastic ATP synthase subunit beta AtCg00480 and Arabidopsis thaliana mitochondrial ATP synthase subunit
  http://www.agrisera.com/en/artiklar/plantalgal-cell-biology/photosynthesis-/protein-standards-quantitation/atpb-protein-standard.html
*  ATP synthase subunit beta antibody | acris-antibodies.com
ATP5B is a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons…
  https://www.acris-antibodies.com/target/atp-synthase-subunit-beta-antibody.htm
*  MTATP6P6 Gene - GeneCards | MTATP6P6 Pseudogene
Complete information for MTATP6P6 gene (Pseudogene), Mitochondrially Encoded ATP Synthase 6 Pseudogene 6, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=MTATP6P6
*  Hepatic overexpression of ATP synthase β subunit activates PI3K/Akt pathway to ameliorate hyperglycemia of diabetic mice |...
ATP synthase β subunit (ATPSβ) had been previously shown to play an important role in controlling ATP synthesis in pancreatic β cells. This study aimed to investigate the role of ATPSβ in regulation of hepatic ATP content and glucose metabolism in diabetic mice. Both ATPSβ expression and ATP content were reduced in the livers of type 1 and type 2 diabetic mice. Hepatic overexpression of ATPSβ elevated cellular ATP content, and ameliorated hyperglycemia of STZ-induced diabetic mice and db/db mice. ATPSβ overexpression increased phosphorylated Akt (pAkt) levels and reduced PEPCK and G6pase expression levels in the livers. Consistently, ATPSβ overexpression repressed hepatic glucose production in db/db mice. In cultured hepatocytes, ATPSβ overexpression increased intracellular and extracellular ...
  http://diabetes.diabetesjournals.org/content/early/2013/11/22/db13-1096?with-ds=yes&cited-by=yes&legid=diabetes%3Bdb13-1096v1
*  ATP5D - ATP synthase subunit delta, mitochondrial precursor - Homo sapiens (Human) - ATP5D gene & protein
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ...
  http://www.uniprot.org/uniprot/P30049
*  blw - ATP synthase subunit alpha, mitochondrial precursor - Drosophila melanogaster (Fruit fly) - blw gene & protein
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the ...
  http://www.uniprot.org/uniprot/P35381
*  Ch. 8: Photosynthesis - Mr. Hoyles Science Page
Mr. Hoyle Biology Lecture Notes Ch. 8: Photosynthesis 8.1 Energy and Life A. Plants and some other living things can use light energy from the sun to make food These organisms are called autotrophs B. Many organisms cannot use the sun’s energy directly These organisms are called heterotrophs, and get their energy from food C. Adenosine triphosphate (ATP) is a compound that cells use to store and release energy ATP is the basic energy source of all cells Cells use energy from ATP to carry out many activities Active transport, synthesis of proteins and nucleic acids, and responses to chemical signals at the cell surface ATP is made up of adenine, a 5-carbon sugar called ribose, and three phosphate groups D. Adenosine diphosphate (ADP) is a compound similar to ATP ADP only has two phosphate groups When energy is available, a cell can store small amounts of energy by adding a phosphate group to ADP to form ATP ...
  https://paperzz.com/doc/840045/ch.-8--photosynthesis---mr.-hoyles-science-page
*  ATP5B Full-Length MS Protein Standard - Creative Proteomics
ATP5B Full-Length MS Protein Standard (NP_001677), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase ...
  https://www.creative-proteomics.com/product/detail-cpfl301638_845.htm
*  ATP5B - Wikipedia
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the beta subunit of the ...
  https://en.wikipedia.org/wiki/ATP5B
*  ATP synthase ecto-α-subunit: a novel therapeutic target for breast cancer | Journal of Translational Medicine | Full Text
In this study we combined several advanced techniques, such as proteomic analysis using the Proteome Lab PF 2D fractionation system, MALDI-TOF/MS and tissue microarray, with functional analysis to identify novel biomarkers for improved prediction of progression, metastasis and response to therapy for breast cancer. The work was also performed in an attempt to better understand molecular mechanisms involved in breast cancer carcinogenesis and metastasis. Our studies revealed one highly over-expressed protein, the α-subunit of ATP synthase, in breast cancer. This observation was validated, refined and extended through a series of IHC on tissue microarray, immunofluorescence and functional analyses. The over-expression of ATP synthase α-subunit was detected by IHC in several different human tumor samples, including breast cancer, hepatocellular carcinoma, colon cancer and prostate cancer (data not shown). Since ATP ...
  https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-9-211
*  Technology - Mitochondrial-Targeted Peptide Modulators of Delta Protein Kinase C Interaction with the d-subunit of F1Fo ATP...
One important event contributing to cardiac injury during reperfusion therapy is an excessive inhibition of the F1Fo ATP synthase by δPKC. Enhancing the return of aerobic ATP production following cardiac ischemia reperfusion would dramatically improve the survival and functionality of the heart. d-subunit F1Fo-derived peptides interfere with or enhance δPKC modulation of F1Fo ATP synthase or ATPase activities. These peptides are first-in-class drugs that potentially protect the myocardium by facilitating a more rapid return of aerobic ATP synthesis following an ischemia reperfusion or hyperglycemic insult. They have potential as solo or adjunctive therapy with other cardio-protective drugs ...
  http://augustaoic.technologypublisher.com/technology/7678
*  ATP Synthase, H Transporting, Mitochondrial F0 Complex, Subunit D ATP Synthase, H+ Transporting, Mitochondrial F0 ...
Compare ATP Synthase, H Transporting, Mitochondrial F0 Complex, Subunit D ATP Synthase, H+ Transporting, Mitochondrial F0 Complex, Subunit D ELISA Kits from leading suppliers on Biocompare. View specifications, prices, citations, reviews, and more.
  http://www.biocompare.com/pfu/110627/soids/2-589908/Assay_Kit/ELISA_ATP_Synthase_H_Transporting_Mitochondrial_F0_Complex_Subunit_D
*  ATP synthase | Article about ATP synthase by The Free Dictionary
Looking for ATP synthase? Find out information about ATP synthase. An enzyme that catalyzes the conversion of phosphate and adenosine diphosphate into adenosine triphosphate during oxidative phosphorylation in mitochondria... Explanation of ATP synthase
  https://encyclopedia2.thefreedictionary.com/ATP+synthase
*  ATPAF2抗体|Abcam中国|Anti-ATPAF2抗体
ATPAF2兔多克隆抗体(ab74235)可与人样本反应并经WB, ELISA实验严格验证。中国75%以上现货,所有产品均提供质保服务,可通过电话、电邮或微信获得本地专属技术支持。
  http://www.abcam.cn/atpaf2-antibody-ab74235.html
*  Probable ATP synthase elisa and antibody
Shop Probable ATP synthase ELISA Kit, Recombinant Protein and Probable ATP synthase Antibody at MyBioSource. Custom ELISA Kit, Recombinant Protein and Antibody are available.
  https://www.mybiosource.com/protein_family.php?root=probable-atp-synthase
*  RCSB PDB - Protein Feature View - ATP synthase subunit epsilon, mitochondrial - P21306 (ATP5E YEAST)
The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex assemblies. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
  http://www.rcsb.org/pdb/protein/P21306
*  RCSB PDB - Protein Feature View - ATP synthase subunit gamma - Q6C338 (Q6C338 YARLI)
The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex assemblies. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
  http://www.rcsb.org/pdb/protein/Q6C338
*  UniProt: A0A0B0HBM8 SOVGS
ID A0A0B0HBM8_SOVGS Unreviewed; 612 AA. AC A0A0B0HBM8; DT 04-MAR-2015, integrated into UniProtKB/TrEMBL. DT 04-MAR-2015, sequence version 1. DT 25-OCT-2017, entry version 14. DE RecName: Full=V-type ATP synthase subunit I {ECO:0000256,RuleBase:RU361189}; GN Name=atpA0I {ECO:0000313,EMBL:KHF26072.1}; GN ORFNames=JV46_14330 {ECO:0000313,EMBL:KHF26072.1}; OS Solemya velum gill symbiont. OC Bacteria; Proteobacteria; Gammaproteobacteria; OC sulfur-oxidizing symbionts. OX NCBI_TaxID=2340 {ECO:0000313,EMBL:KHF26072.1, ECO:0000313,Proteomes:UP000030856}; RN [1] {ECO:0000313,EMBL:KHF26072.1, ECO:0000313,Proteomes:UP000030856} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=WH {ECO:0000313,EMBL:KHF26072.1, RC ECO:0000313,Proteomes:UP000030856}; RX PubMed=25342549; DOI=10.1186/1471-2164-15-924; RA Dmytrenko O., Russell S.L., Loo W.T., Fontanez K.M., Liao L., RA Roeselers G., Sharma R., Stewart F.J., Newton I.L., Woyke T., Wu D., RA Lang J.M., Eisen J.A., ...
  http://www.genome.jp/dbget-bin/www_bget?uniprot:A0A0B0HBM8_SOVGS