Gastrointestinal involvement in langerhans cell histiocytosis: consider treatment as for multi-system disease | Archives of...
Results Dual therapy consisting of vinblastine and prednisolone was commenced with quick regression of her bone and skin ... Aims Langerhans cell histiocytosis (LCH) is a rare disorder characterised by abnormal proliferation of the Langerhans cell.1 ... Gastrointestinal involvement in langerhans cell histiocytosis: consider treatment as for multi-system disease ... Gastrointestinal involvement in langerhans cell histiocytosis: consider treatment as for multi-system disease ...http://adc.bmj.com/content/97/Suppl_1/A58.2
Langerhans Cell Histiocytosis
Important It is possible that the main title of the report Langerhans Cell Histiocytosis is not the name you expected. Please ... Most affected individuals have single or multiple bone lesions characterized by lytic lesions (holes in the bones). Although ... Langerhans Cell Histiocytosis. Important It is possible that the main title of the report Langerhans Cell Histiocytosis is not ... Langerhans cell histiocytosis was chosen because it seemed that the Langerhans cells might play a central role in the ...https://www.webmd.com/children/langerhans-cell-histiocytosis
Developmental Disorders of the Lymphatics: The effect of lenalidomide on rare blood disorders: Langerhans cell histiocytosis,...
This led to complete regression of CNS infiltrates on MRI but fluorodeoxyglucose accumulation in bone lesions did not change. ... Conclusion: We showed an effect of lenalidomide in Langerhans cell histiocytosis and in Castleman disease. The treatment led to ... The effect of lenalidomide on rare blood disorders: Langerhans cell histiocytosis, multicentric Castleman disease, POEMS ... We observed an excellent effect of lenalidomide in multifocal aggressive, repeatedly relapsing Langerhans cell histiocytosis ...http://lymphsystemdisorders.blogspot.com/2012/12/the-effect-of-lenalidomide-on-rare.html
Herpes Simplex Virus and Langerhans Cell Histiocytosis
The histological feature is granuloma-like proliferation of langerhans-type dendritic cells. Although the possible role of ... Langerhans cell histiocytosis (LCH) is a rare histiocytic proliferative disorder of unknown etiology and mainly affects young ... Langerhans cell histiocytosis: a primary viral infection of bone? Human herpes virus 6 latent protein detected in lymphocytes ... Langerhans cells are a type of non-lymphoid mononuclear cells involved in inflammatory responses; LCH is the neoplastic ...http://ijp.iranpath.org/article_27988.html
Combination Chemotherapy in Treating Young Patients With Langerhans Cell Histiocytosis - Full Text View - ClinicalTrials.gov
Multifocal bone disease (i.e., lesions in 2 or more different bones) ... Childhood Langerhans Cell Histiocytosis Drug: leucovorin calcium Drug: methotrexate Drug: prednisolone Drug: vinblastine ... Genetics Home Reference related topics: Langerhans cell histiocytosis Genetic and Rare Diseases Information Center resources: ... Histiocytosis, Langerhans-Cell. Lymphatic Diseases. Lung Diseases, Interstitial. Lung Diseases. Respiratory Tract Diseases. ...https://clinicaltrials.gov/ct2/show/NCT00276757?cond=%22Langerhans+cell+histiocytosis%22&rank=1
Pulmonary Langerhans Cell Histiocytosis - Pulmonary Disorders - Merck Manuals Professional Edition
Bone pain due to bone cysts (18%), rash (13%), and polyuria due to diabetes insipidus (5%) are the most common manifestations ... Pulmonary Langerhans Cell Histiocytosis (Eosinophilic Granuloma; Pulmonary Granulomatosis X; Pulmonary Langerhans' Cell ... Pulmonary Langerhans cell histiocytosis (PLCH) is proliferation of monoclonal Langerhans cells in lung interstitium and ... plasma cells, neutrophils, and eosinophils. PLCH is one manifestation of Langerhans cell histiocytosis, which can affect organs ...http://www.merckmanuals.com/professional/pulmonary-disorders/interstitial-lung-diseases/pulmonary-langerhans-cell-histiocytosis?Ref=n&ItemId=v8544792&RefId=x&Speed=256&Plugin=WMP&Error=
Combination Chemotherapy in Treating Young Patients With Langerhans Cell Histiocytosis - Full Text View - ClinicalTrials.gov
Multifocal bone disease (i.e., lesions in 2 or more different bones) ... Combination Chemotherapy in Treating Young Patients With Langerhans Cell Histiocytosis. The safety and scientific validity of ... Childhood Langerhans Cell Histiocytosis Drug: leucovorin calcium Drug: methotrexate Drug: prednisolone Drug: vinblastine ... Genetics Home Reference related topics: Langerhans cell histiocytosis Genetic and Rare Diseases Information Center resources: ...https://clinicaltrials.gov/ct2/show/study/NCT00276757?cond=%22Langerhans+cell+histiocytosis%22&
Incidence and clinical features of langerhans cell histiocytosis in the UK and Ireland | Archives of Disease in Childhood
... bone marrow). Three children died, two of whom were diagnosed post mortem. ... Objectives: There are few published studies on epidemiology of Langerhans Cell Histiocytosis (LCH). We undertook a survey to ... Incidence and clinical features of langerhans cell histiocytosis in the UK and Ireland ... Incidence and clinical features of langerhans cell histiocytosis in the UK and Ireland ...http://adc.bmj.com/content/early/2008/12/05/adc.2008.144527
Treatment of Langerhans cell histiocytosis bone lesions with zoledronic acid: a case series.
Langerhans) cells. Although uncommon, it is potentially fatal and carries significant morbidity. Bone involvement is ... Langerhans cell histiocytosis (LCH) is a rare disease caused by a clonal proliferation of specialized dendritic ( ... Langerhans cell histiocytosis (LCH) is a rare disease caused by a clonal proliferation of specialized dendritic (Langerhans) ... cells. Although uncommon, it is potentially fatal and carries significant morbidity. Bone involvement is particularly ...http://www.biomedsearch.com/nih/Treatment-Langerhans-cell-histiocytosis-bone/21519845.html
March 2015 - Volume 34 - Issue 3 : The Pediatric Infectious Disease Journal
Kingella Kingae DNA in Langerhans Cell Histiocytosis of Bone. El Houmami, Nawal; Dubourg, Grégory; Minodier, Philippe; More ...https://journals.lww.com/pidj/Abstract/2015/03000/I
July 2014 - Volume 36 - Issue 5 : Journal of Pediatric Hematology/Oncology
Symptomatic Bone Langerhans Cell Histiocytosis Treated at Diagnosis or After Reactivation With Indomethacin Alone. Braier, ... Phagocytosis of Bafilomycin A1-treated Apoptotic Neuroblastoma Cells by Bone Marrow-derived Dendritic Cells Initiates a CD8α+ ... Novel t(2;12)(q31;p13) in a Case of Pediatric T-cell Acute Lymphoblastic Leukemia. Parihar, Mayur; Gupta, Anurag; Remani, Arun ... Renal Medullary Carcinoma in a White Adolescent With Sickle Cell Trait. Daher, Paul; Bourgi, Ali; Riachy, Edward; More ...https://journals.lww.com/jpho-online/Abstract/2014/07000/href
Protocols and Video Articles Authored by Luis Lassaletta
Petrous Bone Langerhans Cell Histiocytosis Treated with Radiosurgery Stereotactic and Functional Neurosurgery. 2007 , Pubmed ID ... Langerhans cell histiocytosis (LCH) is a rare disease that may show as a solitary or multifocal lesion of bone, soft tissue or ... Quality Standards for Bone Conduction Implants Acta Oto-laryngologica. 2015 , Pubmed ID: 26223816 Bone conduction implants are ... We report a case of IMT of the temporal bone in a young man presenting with a progressive hearing loss. Three years after ...https://www.jove.com/author/Luis_Lassaletta
Histiocytosis Differential Diagnoses
Such a description excludes diseases in which infiltration of these cells occurs in response to a primary pathology. ... Epidermal Langerhans cells are derived from cells originating in bone marrow. Nature. 1979 Nov 15. 282(5736):324-6. [Medline]. ... Differential In situ cytokine profiles of Langerhans-like cells and T cells in Langerhans cell histiocytosis: abundant ... Lack of T-cell receptor gene rearrangements in cells involved in Langerhans cell histiocytosis. Cancer. 1995 Mar 1. 75(5):1162- ...https://emedicine.medscape.com/article/958026-differential
pediatricradiologyflash Flashcards by Scott P | Brainscape
Benign: Osteochondroma, Aneurysmal bone cyst, Mesenchymal hamartoma, Langerhans cell histiocytosis, Fibrous dysplasia, ... Sickle cell disease. Congenital obstructive anomalies of the biliary tract. Total parenteral nutrition. Furosemide treatment. ... Sickle cell disease. Glycogen storage disease. Amyloidosis. Bilateral Wilms' tumor. Acute glomerulonephritis. Acquired immune ... Sickle-cell disease. Hypercalciuria. Renal tubular acidosis. Medullary sponge kidney. Hyperparathyroidism. Drugs (furosemide. ...https://www.brainscape.com/flashcards/pediatricradiologyflash-3793356/packs/5656497
Langerhans cell histiocytosis - Wikipedia
... is a rare disease involving clonal proliferation of Langerhans cells, abnormal cells deriving from bone marrow and capable of ... "Langerhans cell histiocytosis - Histiocyte Society Evaluation and Treatment Guidelines". April 2009. "Langerhans Cell ... This primary bone involvement helps to differentiate Eosinophilic Granuloma from other forms of Langerhans Cell Histiocytosis ( ... who is ultimately diagnosed with Langerhans cell histiocytosis. Langerhans cell histiocytosis is occasionally misspelled as " ...https://en.wikipedia.org/wiki/Langerhans_cell_histiocytosis
Langerhans cell histiocytosis - Biology-Online Dictionary
The lytic bone lesion is a hallmark of Langerhans cell histiocytosis.2 ... Histiocytes are reticular connective tissue macrophage or a dendritic cell. They came from the stem cells of the bone marrow, ... Langerhans cell. Reference(s): 1 Histiocyte. Retrieved from []. 2 Shreve, P. & Townsend, D. (2011). Clinical PET-CT in ... Langerhans cells are components of the lesions. Its symptoms include inflammation, lethargy, fever, and weight loss. There is ...https://www.biology-online.org/dictionary/Histiocytosis_langerhans-cell
Antibodies against human CSF-1R - HOFFMANN-LA ROCHE INC.
"Presence of osteoclast-like multinucleated giant cells in the bone and monostotic lesions of Langerhans cell histiocytosis" J. ... such as CHO cells, NS0 cells, SP2/0 cells, HEK293 cells, COS cells, yeast, or E. coli cells, and the antibody is recovered from ... Histiocytosis X (also called Langerhans cell histiocytosis, LCH) is a proliferative disease of Langerhans dendritic cells that ... In addition expression of CSF-1R has been reported in Langerhans cells in skin, a subset of smooth muscle cells (Inaba, T., et ...http://www.freepatentsonline.com/9169323.html
An Study of 18F Sodium Fluoride Whole Body Scans in Patients for Whom 99mTc Bone Scans Would Normally be Indicated
... clinicaltrials.gov To show the usefulness of using locally produced 18F Sodium Fluoride for PET bone scans, in place of 99m ... Pituitary gland and bone involvement of Langerhans cell histiocytosis in a boy and brief review of the literature. ... Study of Bone Disease in Older HIV-infected Adults. This study will look to see if there are changes in the blood cells that ... Bone is the third metastatic site after liver and lungs. Bone metastases occur in one out of three lung cancers and are usually ...https://www.bioportfolio.com/resources/trial/68055/An-Study-of-18F-Sodium-Fluoride-Whole-Body-Scans-in-Patients-for.html
ScopeMed.org - Deposit for Medical Articles
Langerhans cell histiocytosis involving bilateral temporal bones in infant patient: a case report. Yahya A. AlQahtani, Abdullah ... Can cyclin D1 be utilized as a second step after basal cell marker for both diagnosis and prognosis of prostatic adenocarcinoma ...http://www.scopemed.org/?term=Mazen%20Alqahtani&sarea=author&b1=Search+ScopeMed
Cosmetics | Free Full-Text | Safety Evaluation of Cosmetic Ingredients: In Vitro Opportunities for the Identification of...
... cell-based, and/or computational methods, the so-called ... Langerhans cells are derived from cells originating in bone ... 5. Antigen presentation to TH cells and memory T-cell generation (immunogenicity). In vitro T-cell activation. [50,65,66]. ... Langerhans cells (LC) represent the second most prominent cell type in the epidermis (2%-5% of the epidermal population). LC ... the evaluation of in vitro effects of chemicals on cells such as human endothelial cells, bronchial epithelial cells, ...http://www.mdpi.com/2079-9284/1/1/61/htm
Surgical treatment of Langerhans cell histiocytosis with bone and soft tissue involvement in pediatric patients. Abstract PDF. ... Muscle strength after ACL reconstruction with bone tendon-bone patellar autograft tested by Cybex II dynamometer. Abstract PDF ... Bone lengthening of congenitally short metacarpus and metatarsus by the callus distraction technique. Abstract PDF. ... The effect of surgical washers used with olive K-wires on bone surface kinetics in external fixation: a biomechanical study. ...http://aott.org.tr/search/author?firstName=Levent&middleName=&lastName=Eralp&affiliation=&country=
Osteosarcoma - NORD (National Organization for Rare Disorders)
Other conditions include Langerhans cell histiocytosis and certain types of bone cysts. Traumatic growing pains can also cause ... Osteoblasts are cells that work to develop new bone. When they become cancerous they may produce an immature form of bone ... noncancerous bone disorder including Paget disease of bone or fibrous dysplasia, which result in increased bone turnover. Bone ... Samarium and radium 223 are radioactive drugs that target areas where bone cells are growing. This includes tumor cells in ...https://rarediseases.org/rare-diseases/osteosarcoma/
Pediatric Radiology News :: Peer reviewed pediatric radiology cases. Radiology teaching files for pediatric radiology,...
Eosinophilic granuloma / monostotic bone lesion of a langerhans cell histiocytosis (LCH) To the case. More radiology images!. ...http://www.kinderradiologie-online.de/index.shtml?Bereich=Nachrichten&lang=en&Year=2010&Month=03
Langerhans cells develop from a lymphoid-committed precursor | Blood Journal
Reconstitution experiments with bone marrow (BM) cells. The BM cells (2 × 106) from C57 BL/Ka Ly 5.2 donor mice were injected ... T cells, B cells, thymic lymphoid CD8+ DCs, and myeloid cells. The percentage of Ly 5.2+ donor cells and of the different cell ... Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset. Immunity. 1995;3:459- ... Langerhans cells (LCs) are specialized dendritic cells (DCs) strategically located in stratified epithelia, such as those of ...http://www.bloodjournal.org/content/96/5/1633?sso-checked=true
Hematopoietic Cell Transplantation and Novel Therapies in Hemophagocytic Lymphohistiocytosis | SpringerLink
Hematopoietic cell transplantation (HCT) is currently the only curative therapy for primary HLH. While HCT carries substantial ... The use of reduced-intensity stem cell transplantation in haemophagocytic lymphohistiocytosis and Langerhans cell histiocytosis ... Hematopoietic cell transplantation for Chediak-Higashi syndrome. Bone Marrow Transplant. 2007;39(7):411-5.CrossRefPubMedGoogle ... Allogeneic hematopoietic stem cell transplantation for patients with hemophagocytic syndrome (HPS) in Japan. Bone Marrow ...https://link.springer.com/chapter/10.1007/978-3-319-59632-7_15