*  Potassium Citrate: The Contributions of Dr. Charles Pak | Kidney Stone Evaluation And Treatment Program
IDIOPATHIC HYPERCALCIURIA (IH) *Control Your Salt for Fewer Stones and Stronger Bones ... Effects of Citrate and Calcium on Bone. Neutralization of chronic acid load ought to spare bone mineral losses, especially when ... The work was not a trial but a bone physiology observation using markers of formation and resorption. As against placebo, ... One interpretation is that bone mineral balance changes were not present. Another is that they were and simply could not be ...
  https://kidneystones.uchicago.edu/potassium-citrate-the-contributions-of-charles-pak-md/
*  Potassium Citrate - DrugBank
Bone Diseases / Metabolic Acidosis / Mineral Metabolism / Physical Capacity / Renal Transplant Patients. 1. ... Hypercalciuria / Renal Stones. 1. 3. Unknown Status. Prevention. Nephrocalcinosis. 1. 4. Not Yet Recruiting. Treatment. ...
  https://www.drugbank.ca/drugs/DB09125
*  Disorders of K, Mg, and Calcium balance - ONA
Hypertension, hyperkalemia, metabolic acidosis, hypercalciuria and low bone density. Normal renal function and low renin/ ... Inhibit bone reabsorption Increases ECa. 4-6 h. 48 h. Biphosphonates. Inhibit bone reabsorption decreasing osteoclast. 24-72 h ... In bone, PTH stimulates the differentiation of osteoblasts into osteoclasts, leading to release of Ca from bone pools. In the ... Prevent hypercalciuria: patients with hypothyroidism reabsorb Ca less efficiently and tend to develop hypercalciuria, with ...
  https://www.oncologynurseadvisor.com/critical-care-medicine/disorders-of-k-mg-and-calcium-balance/article/586320/
*  Vitamin D - wikidoc
... hypercalciuria and bone loss occurred in four patients with documented vitamin D toxicity.[40] Another study showed elevated ... Osteoporosis, a condition characterized by reduced bone mineral density and increased bone fragility. ... a bone-thinning disorder that occurs exclusively in adults and is characterised by proximal muscle weakness and bone fragility ... Deficiency results in impaired bone mineralization, and leads to bone softening diseases, rickets in children and osteomalacia ...
  http://www.wikidoc.org/index.php/Vitamin_D
*  Nephrolithiasis and Nephrocalcinosis | SpringerLink
Malluche HH, Tschoepe W, Ritz E, Meyer-Sabellek W, Massry SG: Abnormal bone histology in idiopathic hypercalciuria. J Clin ... Parfitt AM: PTH and osteoblasts, the relationship between bone turnover and bone loss, and the state of the bones in primary ... Coe FL, Parks JH, Moore E: Familial idiopathic hypercalciuria. N Engl J Med 300: 337-340, 1979.PubMedCrossRefGoogle Scholar ... Meches K, Szelid ZS: Autosomal dominant inheritance of hypercalciuria. Eur J Pediatr 133: 239-242, 1980.CrossRefGoogle Scholar ...
  https://link.springer.com/chapter/10.1007/978-1-4757-6632-5_8
*  Renal Diseases and Skeletal Health | Springer for Research & Development
Recent clinical observations underline the link between bone disease and disturbances of mineral metabolism with increased ... Bone disease in idiopathic hypercalciuria. Curr Opin Nephrol Hypertens. 2006;15:394-402.CrossRefPubMedGoogle Scholar ... When bone mass fails to predict bone failure. Calcif Tissue Int. 1993;53(Suppl. 1):S7-13.CrossRefPubMedGoogle Scholar ... Bone mineral density predicts fractures in chronic kidney disease. J Bone Miner Res. 2015;30:913-919 8.CrossRefPubMedGoogle ...
  https://rd.springer.com/chapter/10.1007%2F978-3-319-75110-8_11
*  Hypophosphatasia - Wikipedia
... hypercalciuria, and chronic bone demineralization". J. Pediatr. 130 (5): 825-8. doi:10.1016/S0022-3476(97)80029-7. PMID 9152296 ... one of the main components of bone, causing rickets in infants and children and osteomalacia (soft bones) in adults. PLP is the ... Bone. 40 (6): 1655-61. doi:10.1016/j.bone.2007.01.020. PMID 17395561. "Hypophosphatasia Signs and Symptoms". Hypophosphatasia. ... In the long bones, there is an abrupt change from a normal appearance in the shaft (diaphysis) to uncalcified regions near the ...
  https://en.wikipedia.org/wiki/Hypophosphatasia
*  Evidence for an intestinal mechanism in hypercalciuria of spontaneously hypertensive rats | Endocrinology and Metabolism
Correction of hypertension for 6 mo failed to abolish the hypercalciuria. Bone Ca deposits were increased in 1-yr-old SHR. Ten- ... Evidence for an intestinal mechanism in hypercalciuria of spontaneously hypertensive rats. K. Lau, D. Zikos, J. Spirnak, B. Eby ... Evidence for an intestinal mechanism in hypercalciuria of spontaneously hypertensive rats. K. Lau, D. Zikos, J. Spirnak, B. Eby ... Evidence for an intestinal mechanism in hypercalciuria of spontaneously hypertensive rats Message Subject (Your Name) has ...
  http://ajpendo.physiology.org/content/247/5/E625
*  Dent's disease - Wikipedia
... hypercalciuria, nephrocalcinosis, metabolic bone disease, progressive kidney failure and a marked male predominance". Quarterly ... The mechanisms by which CLC-5 dysfunction results in hypercalciuria and the other features of Dent's disease remain to be ... Because of its rather rare occurrence, Dent's disease is often diagnosed as idiopathic hypercalciuria, i.e., excess calcium in ... Amiloride also increases distal tubular calcium reabsorption and has been used as a therapy for idiopathic hypercalciuria. A ...
  https://en.wikipedia.org/wiki/Dent's_disease
*  Hereditary causes of kidney stones and chronic kidney disease | SpringerLink
... familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC), and primary hyperoxaluria (PH) are rare but imp ... The ClC-5 knockout mouse model of Dent's disease has renal hypercalciuria and increased bone turnover. J Bone Miner Res 18:615- ... hypercalciuria, nephrocalcinosis, metabolic bone disease, progressive renal failure and a marked male predominance. Q J Med 87: ... Hampson G, Konrad MA, Scoble J (2008) Familial hypomagnesaemia with hypercalciuria and nephrocalcinosis (FHHNC): compound ...
  https://link.springer.com/article/10.1007/s00467-012-2329-z
*  neilbaum.net
h y p e rcalciuria withlow bone density Hypercalcemia:. Hypercalciuria with Low Bone Density and. Normal Serum Ca:. Urocit®-K ... FASTING HYPERCALCIURIA w Normal PTH. a b s o r p t i v eh y p e rc a l c i u r i a U r i n a ry Ca , 250 mg/day on StoneRisk® ... 5 g bid with oxalate restriction in TZ resistance/intolerance without bone disease ABSORPTIVE HYPERCALCIURIA TYPE II. , 250 mg/ ... If possible,bone density with hypercalcemia or markedh y p e rc a l c i u r i a SIMPLIFIED AMBULATORY EVALUATION. 1. 24-hour ...
  http://diseasepdf.com/n/neilbaum.net1.html
*  ZEMPLAR INJECTION (Paricalcitol) dosage, indication, interactions, side effects | EMPR
Concomitant aluminum-containing preparations (eg, antacids, phosphate binder); may cause aluminum bone toxicity. ... Diarrhea, nasopharyngitis, dizziness, vomiting, hypertension, hypersensitivity, nausea, edema; hypercalcemia, hypercalciuria, ...
  http://www.psychiatryadvisor.com/zemplar-injection/drug/3162/
*  Calcitriol (Systemic) (Professional Patient Advice) - Drugs.com
... hypercalciuria, hyperphosphatemia and adynamic bone disease. Withhold pharmacologic doses of vitamin D and its derivatives ... Parenteral aluminum exposure of ,4 to 5 mcg/kg/day is associated with CNS and bone toxicity; tissue loading may occur at lower ... It reduces PTH levels and improves calcium and phosphate homeostasis by stimulating bone resorption of calcium and increasing ... or bone pain), signs of fluid and electrolyte problems (mood changes, confusion, muscle pain or weakness, abnormal heartbeat, ...
  https://www.drugs.com/ppa/calcitriol-systemic.html
*  IDIOPATHIC CALCIUM PHOSPHATE STONE FORMERS
Hi Al, Idiopathic hypercalciuria is a cause of bone disease, and I suspect you are an example. The elevated urine pH and 20% ... IDIOPATHIC HYPERCALCIURIA (IH) *Control Your Salt for Fewer Stones and Stronger Bones ... My father and I both have had chronic issues with hypercalciuria, bone loss, and unexplained chronic tight muscles. However, my ... cause bone disease! the same bone disease already known to be caused by MSK as well. But you say "whatever the cause" the ...
  https://kidneystones.uchicago.edu/idiopathic-calcium-phosphate-stone-formers/
*  Hyperchloremic Acidosis
Buffering of the chronic acid load by the bone, causing bone dissolution and promoting hypercalciuria ... Hypercalciuria and hypocitraturia are present, so there is a propensity to nephrolithiasis and nephrocalcinosis. Most of the ... Hypercalciuria, nephrolithiasis, and nephrocalcinosis are also prevented when alkali therapy is started in the early stages of ... This is probably due in part to the release of calcium and phosphate during bone buffering of the excess protons. Decreased ...
  http://misc.medscape.com/pi/android/medscapeapp/html/A240809-business.html
*  Hypophosphatemia
... hypercalciuria, bone pain, muscle weakness, and high levels of 1,25 dihydroxyvitamin D-3. The cause of this disorder is an ... Bone Biopsy. Bone biopsy is the only method for defining bone pathology. Hyperparathyroidism and osteomalacia may both have ... Bone films and bone densitometry studies can help determine the severity of the bone loss that has occurred. ... Bone loses approximately 300 mg of phosphate per day, but that is generally balanced by an uptake of 300 mg. Bone metabolism of ...
  http://misc.medscape.com/pi/android/medscapeapp/html/A242280-business.html
*  JCI - Renal tubular NEDD4-2 deficiency causes NCC-mediated salt-dependent hypertension
... hypercalciuria, normomagnesemia, and low bone mineral density. J Clin Endocrinol Metab. 2002;87(7):3248-3254.. View this ... Moreover, the constitutive Nedd4LPax8/LC1 KO mice showed decreased plasma aldosterone (Figure 6D) and hypercalciuria (Table 2 ... Under a high-Na+ diet, KO mice exhibited hypercalciuria and increased blood pressure, which were reversed by thiazide treatment ... PHAII patients and mouse models with overactive NCC display hypercalciuria that can be treated by thiazides, whereas ...
  https://www.jci.org/articles/view/61110
*  Soluble adenylyl cyclase - Wikipedia
... characterization of a gene with base substitutions associated with the absorptive hypercalciuria phenotype and low spinal bone ... Bone density experiments in mouse calvaria cultured indicates that HCO−3-sensing sAC is a physiological appropriate regulator ... of bone formation and/or reabsorption. sAC activation by bicarbonate necessary for motility and other aspects of capacitation ...
  https://en.wikipedia.org/wiki/Soluble_adenylyl_cyclase
*  Calcium - B-Healthy
With hypercalcemia, hypercalciuria, hyperparathyroidism, bone tumors, and sarcoidosis; in chronic renal failure patients, ... AdvaCAL , Alka-Mints , Apo-Cal , atomic number 20, Bica , Bo-Ne-Ca , bone meal, bovine cartilage, Ca, Cal-100 , Calcanate , ... Orlistat (Xenical , Alli ) has been shown to induce a relative increase in bone turnover (increased resorption or bone loss), ... Inhaled steroids have been reported to disturb normal bone metabolism, and they are associated with a decrease in bone mineral ...
  http://www.bhealthyonline.com/ns/DisplayMonograph.asp?storeID=XPJ5GAQTH9S92JS100AKHMCCQAUX6Q83&DocID=bottomline-calcium
*  Shamir Tuchman - Children's National Health System
... bone mineral metabolism alterations in hypercalciuria, and vitamin D status in kidney transplant patients. ...
  https://childrensnational.org/research-and-education/about-cri/faculty-and-leadership-directory/shamir-tuchman
*  Oliver Wrong - Wikipedia
... hypercalciuria, nephrocalcinosis, metabolic bone disease, progressive renal failure and a marked male predominance". QJM. 87: ... hypercalciuria, nephrocalcinosis, metabolic bone disease, progressive renal failure and a marked male predominance". QJM. 87: ...
  https://en.wikipedia.org/wiki/Oliver_Wrong