*  Acta Crystallogr Sect F Struct Biol Cryst Commun Volume 65(Pt 12); 2009 December 1
Crystallization and preliminary X-ray crystallographic analysis of blood coagulation factor V-activating proteinase (RVV-V) ... from Russell's viper venom. Daisuke Nakayama, Youssef Ben Ammar, Soichi Takeda. The crystallization and preliminary X-ray ... crystallographic analysis of blood coagulation factor V-activating proteinase are reported. The best crystal diffracted to 1.9 ...
  http://pubmedcentralcanada.ca/pmcc/issues/54752/
*  Comparison of green pit viper and Agkistrodon halys antivenom in inhibition of coagulopathy due to Trimeresurus albolabris...
Prolonged defibrination syndrome after green pit viper bite with persisting venom activity in patient's blood. Am J Clin Pathol ... Blood coagulation abnormalities associated with envenoming by Trimeresurus albolabris in Hong Kong. Singapore Med J 1993;34:145 ... venom. The venom promoted clotting and depleted fibrinogen level in a dose-dependent fashion. After incubation of the venom ... Blood 2001;97:3989-91. CrossRef 13. Li S, Wang J, Zhang X, et al. Proteomic characterization of two snake venoms: Naja naja ...
  http://hkmj.org/abstracts/v23n1/13.htm
*  Russellysin - Wikipedia
Russellysin (EC 3.4.24.58, Russell's viper venom factor X activator, RVV-X, blood-coagulation factor X activating enzyme, ... Russell's viper blood coagulation factor X activator, RVV-V) is an enzyme. This enzyme catalyses the following chemical ... "Coagulation factor X activating enzyme from Russell's viper venom (RVV-X). A novel metalloproteinase with disintegrin (platelet ... Has no action on insulin B chain This enzyme is present in the venom of Russell's viper (Vipera russelli). Furie, B.C.; Furie, ...
  https://en.wikipedia.org/wiki/Russellysin
*  venom facts, information, pictures | Encyclopedia.com articles about venom
Make research projects and school reports about venom easy with credible articles from our FREE, online encyclopedia and ... The venom of the gaboon viper is both hemotoxic and neurotoxic. Venoms may also contain agglutinins, which promote coagulation ... Hemotoxins perforate the blood vessels, causing hemorrhage, and hemolysins dissolve the red blood cells. The venom of the fer- ... ven·om·ous / ˈvenəməs/ • adj. (of animals, esp. snakes, or their parts) secreting venom; capable of injecting venom by means of ...
  http://www.encyclopedia.com/plants-and-animals/zoology-and-veterinary-medicine/zoology-general/venom
*  Western Gaboon Viper - Bitis gabonica - Overview - Encyclopedia of Life
Effect of gaboon viper (Bitis gabonica) venom on blood coagulation, platelets, and the fibrinolytic enzyme system. Journal of ... The Gaboon viper (Bitis gabonica) its biology, venom components and toxinology. Toxicon 22 (5): 669-694. ... East African Gaboon viper. Central, eastern and southern Africa. B. g. rhinoceros. (Schlegel, 1855). West African Gaboon viper ... True Vipers: Natural History and Toxinology of Old World Vipers. Malabar, Florida: Krieger Publishing Company. 359 pp. ISBN 0- ...
  http://eol.org/pages/1057054/overview
*  Gaboon viper - Wikipedia
Effect of gaboon viper (Bitis gabonica) venom on blood coagulation, platelets, and the fibrinolytic enzyme system. Journal of ... Two to three electrical bursts within a space of five seconds apart were enough to empty the venom glands. The Gaboon vipers ... The Gaboon viper (Bitis gabonica) its biology, venom components and toxinology. Toxicon 22 (5): 669-694. Morris PA. 1948. Boy's ... However, the venom glands are enormous and each bite produces the largest quantities of venom of any venomous snake; this is ...
  https://en.wikipedia.org/wiki/Gaboon_viper
*  CLINICAL CHEMISTRY 36-C: Animal and Plant Toxins
Prematurely activates factor X of the blood coagulation resulting in net anticoagulation. Viper and elapid venoms. ... Elapid venoms. Disintegrins. Anticoagulants that bind to GPIIb/IIIa receptor on platelets. Wide spread in viper venoms and also ... Pit-viper venoms, gila monster venoms. PLA2s. Hemorrhagic. PLA2s with a myriad of activities are scattered widely throughout ... Vipers and colubrids. Prothrombin activators. Premature activation of prothrombin in the coagulation cascade resulting in net ...
  http://clinicalchemistry36-c.blogspot.com/2011/07/animal-and-plant-toxins.html
*  GPM.1.8.2.0003.15 Determination of blood coagulation factors activity | Pharmacopoeia.ru
GPM.1.8.2.0003.15 Determination of blood coagulation factors activity Ministry of Health of the Russian Federation General ... Add 25 µL of the specific factor X activator obtained from the venom of Russell's viper into each well, and incubate at 37 ± ... Coagulation factor activity testing is based on two approaches:. *One-step method. Blood coagulation recovered in factor ... Activated blood coagulation factors. The determination is performed by coagulometry.. A solution of the tested sample is ...
  http://pharmacopoeia.ru/en/ofs-1-8-2-0003-15-opredelenie-aktivnosti-faktorov-svertyvaniya-krovi/
*  Snake venom factor V activator - Wikipedia
Kisiel, W.; Canfield, W. (1981). "M. Snake venom proteases that activate blood-coagulation factor V". Methods Enzymol. 80: 275- ... from Russell's viper venom. Identification of isoproteins RVV-Vα, -Vβ and -Vγ and their complete amino acid sequences". J. Biol ... Snake venom factor V activator (EC 3.4.21.95) is an enzyme. This enzyme catalyses the following chemical reaction Fully ... Snake venom factor V activator at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and Cellular ...
  https://en.wikipedia.org/wiki/Snake_venom_factor_V_activator
*  US4287180A - Method for treating blood clotting factor inhibitors - Google Patents
... about from 1-10 are used in therapeutically effective amounts to treat blood clotting factor inhibitors. ... Path." 36(3):214(1961). Russell's viper venom and cephalin were obtained from Burroughs Wellcome & Co. and the Hyland Division ... Blood coagulation is best visualized as a cascade of reactions between formed and soluble blood components in which most ... Blood coagulation is an exceedingly complex process. The interaction of various blood components which eventually gives rise to ...
  https://patents.google.com/patent/US4287180?oq=flatulence
*  Snake venom - Wikipedia
... saw-scaled vipers, bushmasters, rattlesnakes) acts more on the vascular system, bringing about coagulation of the blood and ... Some of the proteins in snake venom have very specific effects on various biological functions including blood coagulation, ... In the vipers, which have the most highly developed venom delivery apparatus, the venom gland is very large and is surrounded ... Boomslang (Dispholidus typus) and twig snake (Thelotornis spp.) venom are toxic to blood cells and thin the blood (hemotoxic, ...
  https://en.wikipedia.org/wiki/Snake_venom
*  Robert Gwyn Macfarlane - Wikipedia
He examined the Venom of many different snakes and isolated the poison of the Russell's Viper to have the strongest blood ... Working in 1951 with Prof Alexander Stuart Douglas at the Blood Coagulation Research Unit in Oxford they jointly discovered a ... Perhaps his greatest contribution to modern medicine was his deciphering of the Enzyme cascade process of blood coagulation. ... 1953 (with R. Biggs) Human Blood Coagulation and its Disorders. Blackwell Scientific Publications, Oxford. 1961 (with A.H.T. ...
  https://en.wikipedia.org/wiki/Robert_Gwyn_Macfarlane
*  Most recent papers with the keyword Thrombelastograph | Read by QxMD
Human plasma was exposed to the venom of three different C. simus subspecies and venoms obtained from B. asper vipers located ... April 2017: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis ... July 2016: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis ... Effects of iron and carbon monoxide on Lachesis muta muta venom-mediated degradation of plasmatic coagulation. ...
  https://www.readbyqxmd.com/keyword/95773
*  Farnesyl Diphosphate Synthase
Serine proteases are main the different parts of viper venom and focus on various stages from the bloodstream coagulation ... Generally they have haemotoxic effects by affecting numerous stages of the blood coagulation system. They can take action ... Venom gland cDNA synthesis To improve the expression from the venom gland genes venom was extracted from an individual specimen ... Snake venom serine proteases are a major component of venom and have been recognized mainly in the venoms of MDV3100 snakes ...
  http://www.ovarian-cancersymptoms.com/category/farnesyl-diphosphate-synthase/
*  Cardiolipin Antibodies
Cardiolipin antibody tests help diagnose the cause of blood clots, recurrent miscarriages or antiphospholipid syndrome (APS). ... antibodies are autoantibodies that can affect blood clotting. ... dilute Russell viper venom test, DRVVT). If cardiolipin ... 2003 September, Modified) Anticardiolipin antibodies (IgG, IgM, IgA). Clinical Coagulation Laboratory Coagulation Test ... There are three classes of cardiolipin antibodies that may be present in the blood: IgG, IgM and/or IgA. The two most commonly ...
  https://labtestsonline.org/tests/cardiolipin-antibodies
*  Approches In Venom Theropy-Akash Dhanak, SlideSearchEngine.com
Approches In Venom Theropy-Akash Dhanak Science-Technology presentation by SKY.AKASHDIP ... Date: Apr 27,2006 'Russell's viper- Daboia russelli' available via http://en.wikipedia.org/wiki/ 'Blood Coagulation' available ... This Venom Has Great effect on the blood coagulation cascade. Slide 15: Factor X Needs Protease Enzyme to potentiate the ... Coagulation Factor X Activating Enzyme from Russell's Viper Venom (RVV-X)'; 267(20), 14109-1411,(1992) Slide 19: Thank You ...
  http://www.slidesearchengine.com/slide/approches-in-venom-theropy-akash-dhanak
*  Coagulation - Wikipedia
... dilute Russell's viper venom time (dRVVT), miscellaneous platelet function tests, thromboelastography (TEG or Sonoclot), ... Coagulation (also known as clotting) is the process by which blood changes from a liquid to a gel, forming a blood clot. It ... Coagulation can physically trap invading microbes in blood clots. Also, some products of the coagulation system can contribute ... Coagulation begins almost instantly after an injury to the blood vessel has damaged the endothelium lining the vessel. Leaking ...
  https://en.wikipedia.org/wiki/Coagulation
*  APTT legal definition of APTT
... dilute Russell viper venom test; TCT, thrombin clotting time; ECT, ecarin clotting time; [C.. The laboratory and the new oral ... Coagulation screening test INR and APTT results from different laboratories for Dabi and Riva samples are summarized in Table 2 ... The long-awaited whole-blood thrombin generation test. ABBREVIATIONS: APC = activated protein C; APTT = activated partial ... Cutaneous and systemic effects of varying doses of brown recluse spider venom in a rabbit model ...
  http://legal-dictionary.thefreedictionary.com/APTT
*  Activated partial thromboplastin time | definition of activated partial thromboplastin time by Medical dictionary
... falsely decreased coagulation factors that corrected upon dilution, a positive dilute Russell's Viper venom assay, and a ... clotting time (coagulation time) the time required for blood to clot in a glass tube; see also clotting. ... Coagulation was assessed by two standard measurements of blood clotting time, activated clotting time (ACT) and activated ... 3) The most commonly used screening assays include the activated partial thromboplastin time and dilute Russell viper venom ...
  https://medical-dictionary.thefreedictionary.com/activated+partial+thromboplastin+time
*  Lupus anticoagulant - Wikipedia
... such as the dilute Russell's viper venom time, or the Kaolin clotting time. Excess phospholipid will eventually correct the ... The presence of prolonged clotting times on a routine plasma test often triggers functional testing of the blood clotting ... Investigators speculate that the antibodies interfere with phospholipids used to induce in vitro coagulation. In vivo, the ... Lupus anticoagulant antibodies in living systems cause an increase in inappropriate blood clotting. The name derives from their ...
  https://en.wikipedia.org/wiki/Lupus_anticoagulant
*  Factor V Leiden - Wikipedia
... dilute Russell's viper venom time) based test or an aPTT based test. In both methods, the time it takes for blood to clot is ... May 1994). "Mutation in blood coagulation factor V associated with resistance to activated protein C". Nature. 369 (6475): 64-7 ... Herskovits AZ, Lemire SJ, Longtine J, Dorfman DM (November 2008). "Comparison of Russell viper venom-based and activated ... The risk of developing a clot in a blood vessel depends on whether a person inherits one or two copies of the factor V Leiden ...
  https://en.wikipedia.org/wiki/Factor_V_Leiden
*  PTT | LabCorp
National Hemophilia Foundation: Learn about Coagulation Disorders. National Heart, Lung, Blood Institute: Blood Diseases and ... Dilute Russell viper venom test (DRVVT) - a test that may be done if the presence of lupus anticoagulant is suspected (See the ... A blood clot in a vein or artery *An acute condition such as disseminated intravascular coagulation (DIC) that may cause both ... For more on this, see the article on the Coagulation Cascade.). How is the sample collected for testing?. A blood sample is ...
  https://www.labcorp.com/help/patient-test-info/ptt
*  Snake Venom Enzymes Proteins Substances Neurotoxic Effect Coagulants Biology Essay
Snake venom is adapted saliva that is formed by distinct glands of only certain species of snakes. The gland which secretes ... ... Repeat blood tests, ECG, at clinically related breaks. Abnormal coagulation must be corrected; watch for spread intravascular ... Snake example: most Vipers and the members of Naja genus. This is milder venom that generally causes only localized symptoms at ... When human is bitten with hemotoxic venom by a snake, the venom decrease blood pressure and increase blood clotting. The venom ...
  https://www.ukessays.com/essays/biology/snake-venom-enzymes-proteins-substances-neurotoxic-effect-coagulants-biology-essay.php
*  Batroxobin - Wikipedia
This then renders the blood more prone to coagulation. An overdose will lead to excessive blood-clotting, which can result in ... The venom batroxobin also induces clots, but does this with or without tissue damage. This is because batroxobin isn't ... venomous species of pit viper found east of the Andes in South America. It is a hemotoxin which acts as a serine protease ... Which leads to a reduction of blood viscosity and blood coagulability. The blood is thinner and there is an increased tendency ...
  https://en.wikipedia.org/wiki/Batroxobin
*  LC2 - Snaclec coagulation factor X-activating enzyme light chain 2 precursor - Daboia siamensis (Eastern Russel's viper) - LC2...
The enzyme activates coagulation factor X (F10) by cleaving the Arg-Ile bond and is also able to activate coagulation factor IX ... Regulatory subunit of the blood coagulation factor X- and IX-activating enzyme. ... Regulatory subunit of the blood coagulation factor X- and IX-activating enzyme. The enzyme activates coagulation factor X (F10 ... "New insights into the functions and N-glycan structures of factor X activator from Russell's viper venom.". Chen H.S., Chen J.M ...
  http://www.uniprot.org/uniprot/Q4PRD2