Loading...
*  Hemophilia Treatment Drugs Market Size, Share, Sales, Growth, Trends, Demand and Forecast to 2021 | Healthcare
The reports we provide are based on a research that covers a magnitude of factors such as technological evolution, economic ... Blood Analysis Sampling Tube Market Growth Opportunities by Regions, Type & Application; Trend Forecast to 2021 ...
  http://beforeitsnews.com/healthcare/2017/03/hemophilia-treatment-drugs-market-size-share-sales-growth-trends-demand-and-forecast-to-2021-2507443.html
*  Correlation of Factor VIIa Values With Factor VII Gene Polymorphism, Fasting and Postprandial Triglyceride Levels, and...
Activation of factor VII bound to tissue factor: a key early step in the tissue factor pathway of blood coagulation. Proc Natl ... Factor VIIc levels were reported to be a risk factor for fatal coronary heart disease (CHD). Factor VIIc and VIIag levels were ... The factor VII AA genotype was associated with a higher factors VIIag and VIIc levels. It was associated with a higher factor ... Correlation of Factor VII Polymorphism With Factor VIIa, VIIc, and VIIag Levels. Of the 395 subjects who had factor VII ...
  http://circ.ahajournals.org/content/98/25/2815
*  GPM.3.3.2.0002.15 Human coagulation factor VII | Pharmacopoeia.ru
GPM.3.3.2.0002.15 Human coagulation factor VII Pharmacopoeia Monograph First Edition The present Pharmacopoeia Monograph ... Coagulation factor IX activity. Coagulation factor IX activity, per vial or millilitre of reconstituted solution, should be ... "Determination of blood coagulation factor activity".specific activity = coagulation factor VII activity / protein content ... Human coagulation factor VII preparations may contain coagulation factors II, IX, and X, protein С and protein S, the content ...
  http://pharmacopoeia.ru/en/fs-3-3-2-0002-15-faktor-svertyvaniya-krovi-vii-cheloveka/
*  CHAPTER 123 HEMOPHILIA A AND HEMOPHILIA B | Free Medical Textbook
Factor Viii Deficiency) Definition and History Etiology and Pathogenesis Genetics Prenatal Diagnosis and Carrier Detection ... Clinical Features Laboratory Features Differential Diagnosis Therapy Course and Prognosis Hemophilia B (Factor IX Deficiency,… ... neutralizes specifically factor VIII and not other blood-clotting factors that influence the PTT (i.e., factors IX, XI, XII, PK ... The factor IX in patients with hemophilia Bm competes with factor X for activation by the factor VIIa/tissue factor complex, ...
  https://medtextfree.wordpress.com/2012/02/09/chapter-123-hemophilia-a-and-hemophilia-b/
*  Factor IX expression in skeletal muscle of a severe hemophilia B patient 10 years after AAV-mediated gene transfer. - Semantic...
... we show persistent factor IX expression in injected muscle tissue. F.IX transcripts were detected in injected skeletal muscle ... Although the procedure appeared safe, circulating F.IX levels remained subtherapeutic (, 1%). Recently, we obtained muscle ... In previous work we transferred a human factor IX-encoding adeno-associated viral vector (AAV) into skeletal muscle of men with ... Blood}, year={2012}, volume={119 13}, pages={3038-41} }. ... Factor IX expression in skeletal muscle of a severe hemophilia ...
  https://www.semanticscholar.org/paper/Factor-IX-expression-in-skeletal-muscle-of-a-sever-Buchlis-Podsakoff/e3aa07b9e467618ed3042df27bf3b24075c60881
*  Coagulation factor XIa | Article about Coagulation factor XIa by The Free Dictionary
Find out information about Coagulation factor XIa. A procoagulant present in normal blood but deficient in hemophiliacs. Also ... known as plasma thromboplastin antecedent Explanation of Coagulation factor XIa ... coagulation factor IX. *coagulation factor IX. *coagulation factor IX , Fc fusion protein ... Related to Coagulation factor XIa: Factor ixa factor XI. [′fak·tər ə′le·vən] (biochemistry) A procoagulant present in normal ...
  https://encyclopedia2.thefreedictionary.com/Coagulation+factor+XIa
*  Hemophilia B
Hereditary factor IX deficiency disease, Christmas disease Hemophilia B is a bleeding disorder that slows the blood clotting ... Factor IX deficiency (hemophilia B) is less common than factor VIII deficiency (hemophilia A), and innovations in therapy for ... The current study describes anti-factor (F) IX antibody profiles in 37 patients who have HB. Anti-FIX IgG4 levels exhibited a ... Survey of the anti-factor IX immunoglobulin profiles in patients with hemophilia B using a fluorescence-based immunoassay. ...
  http://diseaseinfosearch.org/Hemophilia+B/3315
*  Coagulation Factor VII Antibodies: Novus Biologicals
Browse our Coagulation Factor VII Antibody catalog backed by our Guarantee+. ... Coagulation Factor VII Antibodies available through Novus Biologicals. ... Blood Coagulation Disorders (20). *. Carcinoma (20). *. Cardiovascular Diseases (20). *. Coronary Heart Disease (20) ...
  https://www.novusbio.com/gene-id/2155?related_pathways=Secretion
*  Clotting factors - Mnemonic - Ramneet Kaur - Medium
Christmas factor, Plasma thromboplastin component (PTC); intrinsic pathway; deficiency leads to hemophilia B. Factor XI - ... Clotting factors:. *The clotting factors are a group of chemicals in the blood which is responsible for the formation of blood ... Factor XIII - Fibrin stabilizing factor (FSF); common pathway; cross-links fibrin.. *Factor VIII & IX are sex-linked characters ... Factor VII - Stable factor, Proconvertin; both extrinsic & intrinsic pathway.. Factor VIII - Antihaemophilic factor (AHF); ...
  https://medium.com/@enulucky/clotting-factors-mnemonic-ef7e68b8c6ba
*  Factor XI - Wikipedia
... factor XII, factor XI, and factor IX). Factor XIa activates factor IX by selectively cleaving arg-ala and arg-val peptide bonds ... "Activation of human blood coagulation factor XI independent of factor XII. Factor XI is activated by thrombin and factor XIa in ... "Expression of human blood coagulation factor XI: characterization of the defect in factor XI type III deficiency". Blood. 79 (6 ... This is thought that this exposes the factor IX binding site of the third apple domain, allowing factor XI's protease activity ...
  https://en.wikipedia.org/wiki/Factor_XI
*  Haemophilia B - Wikipedia
... is a blood clotting disorder caused by a mutation of the factor IX gene, leading to a deficiency of factor IX. It is the second ... Factor IX when activated activates factor X which helps fibrinogen to fibrin conversion. Factor IX becomes active eventually in ... which has a longer half life than factor VIII and as such factor IX can be transfused less frequently. Blood transfusions may ... which allows for neatly packaged bottles of factor IX concentrates. With the rise of factor IX concentrates it became easier ...
  https://en.wikipedia.org/wiki/Haemophilia_B
*  A Comprehensive Generic Drug Naming Resource - DrugPatentWatch
blood factor IX. octakin (see -kin). interleukin-8 analogues and derivatives. -octadekin (see -kin). interleukin-18 human ... combination of two different types of colony stimulating factors. -dodekin (see -kin). interleukin-12 analogues and derivatives ... granulocyte macrophage colony stimulating factor (GM-CSF) types substances. -grastim (see -stim). granulocyte colony ... perfluorinated compounds used as blood substitutes and/or diagnostic agents. -peridol (see -perone). antipsychotics, ...
  https://www.drugpatentwatch.com/blog/a-comprehensive-generic-drug-naming-resource/
*  Open-Label Single Ascending Dose of Adeno-associated Virus Serotype 8 Factor IX Gene Therapy in Adults With Hemophilia B - Full...
Hemophilia B is a genetic X-linked bleeding disorder caused by a deficiency in blood-clotting Factor IX (FIX) activity. FIX is ... The purpose of this study is to evaluate the safety of single ascending IV doses of a Factor IX (FIX) Gene Therapy in up to 16 ... Open-Label Single Ascending Dose of Adeno-associated Virus Serotype 8 Factor IX Gene Therapy in Adults With Hemophilia B. This ... Drug Information available for: Factor IX Complex Genetic and Rare Diseases Information Center resources: Hemophilia Hemophilia ...
  https://clinicaltrials.gov/ct2/show/NCT01687608
*  KAKEN - Research Projects | Studies on the Activity Measurement for Blood Proteases using their Monoclonal Antibodies (KAKENHI...
2Glc-O-Ser-53 Found in the First Epidermal Growth Factor-like Domain of Bovne Blood Clotting Factor IX.' J. Biol. Chem.265(4). ... Publications] Suehiro,K.,et al.: 'Blood Clotting Factor IX Nagoya 3:The Molecular Defect of Zymogen Activation Caused by an ... Publications] Suehiro,K.,et al.: 'Blood Clotting Factor IX Nagoya 3:The Molecular Defect of Zymogen Activation Caused by an ... Factor VII / tissue factor / Synthetic Peptide substrate / Extrinsic coagulation / gamma-Gla domain / Blood protease / ...
  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-02557016/
*  Monoclonal Antibody to an Epitope on the Heavy Chain of Factor IX Missing in Three Hemophilia-B Patients By - Semantic Scholar
The antibody inhibited factor IX procoagulant activity. but did not appreciably interfere with the cleavage of factor IX by ... Bovine factor IX had little crossreactivity with the monoclonal antibody. Of 55 patient ... After gel electrophoresis and blotting of reduced samples of factor IXa. the antibody bound exclusively to the heavy chain. ... factor XIa nor with the binding of antithrombin-lll-heparin complex to factor IXa. The antigen-solid-phase-antibody complex ...
  https://www.semanticscholar.org/paper/Monoclonal-Antibody-to-an-Epitope-on-the-Heavy-of-Arthur-R./64073691d9ba2ce8f850cba41f474a5bd32d2949
*  Patent US4540573 - Undenatured virus-free biologically active protein derivatives - Google Patents
A mammalian blood protein-containing composition such as whole blood, plasma, serum, plasma concentrate, cryoprecipitate, ... factor IX or the prothrombin complex (factors II, VII, IX, X), fibrinogen and any other blood derivative including HBsAg used ... factor II, factor VII, factor VIII, factor IX, factor X, factor XIII, factor I, immunoglobulins, prealbumin, retinol-binding ... factor II, factor VII, factor VIII, factor IX, factor X, fibrinogen and IgM. Additionally, the present invention concerns ...
  http://www.google.ca/patents/US4540573
*  Avigen's Gene Therapy Approach Shows Promise In Treating Hemophilia B With,,Single Intramuscular Admi...( Long-Term Factor IX...
Long-Term Factor IX Expression and Improved Blood Clotting Time Ac...SEATTLE WASHINGTON (May 28 1998): Scientists at Avigen Inc ... Long-Term Factor IX Expression and Improved Blood Clotting Time Achieved. SEATTLE, WASHINGTON (May 28, 1998): Scientists at ... that shows the ability of AAV-mediated gene therapy to achieve sustained production of factor IX resulting in improved blood ... A single intramuscular administration of an AAV vector containing the gene for factor IX was given. The animals showe. '"/> ...
  http://news.bio-medicine.org/biology-news-2/Avigens-Gene-Therapy-Approach-Shows-Promise-In-Treating-Hemophilia-B-With-0D-0ASingle-Intramuscular-Administration-14573-1/
*  Ixinity: Indications, Side Effects, Warnings - Drugs.com
Blood clots have happened with Ixinity (factor IX (recombinant)). Tell your doctor if you have ever had a blood clot. Talk with ... If you have an allergy to Factor IX or any other part of Ixinity (factor IX (recombinant)). ... factor IX (recombinant)) come to room temperature before mixing. Do not heat Ixinity (factor IX (recombinant)). ... Generic Name: Factor IX (Recombinant) (FAK ter nyne ree KOM be nant). Brand Name: BeneFIX, Ixinity, Rixubis ...
  https://www.drugs.com/cdi/ixinity.html
*  Genetically Modified Organisms by Kathryn Davis on Prezi
Polly produced the human protein Factor IX, a blood clotting protein used to treat hemophilia. The protein was secreted in ... 3D image of Factor IX protein. How can genetically modified mammals be useful for human health?. Transgenic Genetically ... This supports this idea that the nutrients in the natural system are the limiting factor.. Phytoremediation. Phytoremediation ...
  https://prezi.com/ccqzv__es7af/genetically-modified-organisms/
*  Correlation Between Vitamin D Status and Bone Mineral Density in Patients With Hemophilia
A deficiency of blood coagulation factor IX inherited as an X-linked disorder. (Also known as Christmas Disease, after the ... The classic hemophilia resulting from a deficiency of factor VIII. It is an inherited disorder of blood coagulation ... A lipid cofactor that is required for normal blood clotting. Several forms of vitamin K have been identified: VITAMIN K 1 ( ...
  https://www.bioportfolio.com/resources/trial/66747/Correlation-Between-Vitamin-D-Status-and-Bone-Mineral-Density-in-Patients-With.html
*  Early safety results promising for Phase I/II trial of gene therapy treatment of hemophilia B - Healthcanal.com : Healthcanal...
The Factor IX protein helps the blood form clots. Individual with hemophilia B lack adequate levels of this clotting factor. ... The patient's Factor IX production remains elevated more than nine months later. Since the infusion the patient has also not ... Levels of the Factor IX protein rose from less than 1 percent to 2 percent of normal after the experimental vector was infused ... Factor IX is needed for normal clot formation. A mutation in the gene that carries instructions for assembling the protein ...
  https://www.healthcanal.com/blood-heart-circulation/12949-early-safety-results-promising-for-phase-iii-trial-of-gene-therapy-treatment-of-hemophilia-b.html
*  BDI Pharma | Now part of McKesson
Factor IV Calcium ions. Factor IX Blood coagulation Factor IX, also known as Christmas Factor (CF) and Plasma Thromboplastin ... A blood plasma derivative product that is rich in coagulation factor VIII and also contains fibrinogen, factor IX, factor VIIa ... Christmas Factor Blood coagulation Factor IX. Also known as Plasma Thromboplastin Component (PTC). In the blood clotting ... Anti-Hemophilic Factor (AHF) Blood coagulation Factor VIII, a protein substance in blood plasma that is essential in the blood ...
  http://www.bdipharma.com/glossary
*  Health Articles: 9. Blood Pressure - Beware of Six Serious Risk Factors
The risk of high blood pressure is quite high and you can't afford to be complacent about it. Some specific risk factors that ... Be in the look out for these risk factors and if one or more of these factors apply to you, you should be cautious to avoid ... There are six risk factors which are more significant. If you have one or more of these factors, then you should take steps to ... Overweight:People who have excess weight are more prone to be affected by high blood pressure. In fact if you are overweight, ...
  http://health-and-fitness-articles-for-you.blogspot.in/2014/10/blood-pressure-beware-of-six-serious.html
*  Polly and Molly - Wikipedia
The protein in question was the human blood clotting factor IX. Another difference from Dolly the Sheep was the source cell ... The transgene that was inserted in the donor somatic cells was designed to express the human clotting factor IX protein in the ... 1997). "Human factor IX transgenic sheep produced by transfer of nuclei from transfected fetal fibroblasts". Science. 278 (5346 ... and deficiency leads to the disease haemophilia B of which treatment requires intravenous infusion of factor IX. The production ...
  https://en.wikipedia.org/wiki/Polly_and_Molly
*  About the theme
GM soybean plants capable of producing factor IX, a protein responsible for blood coagulation. Hemophilic patients do not ... they experienced significant growth in the vitamin content found in their blood. ...
  https://www.embrapa.br/en/tema-transgenicos/sobre-o-tema