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*  Biological Characterization of an Improved Pyrrole-Based Colchicine Site Agent Identified through Structure-Based Design |...
Biological Characterization of an Improved Pyrrole-Based Colchicine Site Agent Identified through Structure-Based Design. ... Biological Characterization of an Improved Pyrrole-Based Colchicine Site Agent Identified through Structure-Based Design ... Correction to: Biological Characterization of an Improved Pyrrole-Based Colchicine Site Agent Identified Through Structure- ... Our previous modeling and biological studies showed that an ethyl ester is optimal at the C2 substitution of the pyrrole, ...
  http://molpharm.aspetjournals.org/content/89/2/287
*  Pyrroles - A Novel Synthetic Method For Pyrrole Derivatives From Nitrodienes | 66638
Pyrrole nucleus is one of the most important heterocycles abundantly found in bioactive natural molecules, forming the ... 1,2,5-Trisubstituted pyrroles display interesting biological properties, such as anti-inflammatory, antipsychotic, spasmolytic ... Pyrroles - A novel synthetic method for pyrrole derivatives from nitrodienes. 6th World Congress on Medicinal Chemistry and ... The electronic properties of pyrrole are important in the context of conducting polymers, where poly-pyrroles have found many ...
  https://www.omicsonline.org/proceedings/pyrroles--a-novel-synthetic-method-for-pyrrole-derivatives-from-nitrodienes-66638.html
*  subject:(Pyrroles) - OATD
"A study of pyrroles in biological materials. - ." 1938. Doctoral Dissertation, McGill University. Accessed March 25, 2018. http ... A study of pyrroles in biological materials. - . [Internet] [Doctoral dissertation]. McGill University; 1938. [cited 2018 Mar ... In the gradual unravelling of the complexities of biological materials, it has become apparent that the pyrrole group of ... In the gradual unravelling of the complexities of biological materials, it has become apparent that the pyrrole group of ...
  https://oatd.org/oatd/search?q=subject%3A%28Pyrroles%29&pagesize=30
*  Pyrrole - Wikipedia
ISBN 1-57259-153-6. . Walsh, C. T., Garneau-Tsodikova, S. & Howard-Jones, A. R. Biological formation of pyrroles: Nature's ... Pyrrole aus Azinen" [Synthesis of pyrrole derivatives: pyrrole from diethyl succinyl succinate, pyrrole from azines]. Berichte ... In contrast, substituted pyrroles (including protected pyrroles) have been used in a broad range of transformations. Pyrroles ... Pyrrole is also weakly acidic at the N-H position, with a pKa of 17.5. Pyrrole was first detected by F. F. Runge in 1834, as a ...
  https://en.wikipedia.org/wiki/Pyrrole
*  Prodigiosin - Wikipedia
Walsh, C. T., Garneau-Tsodikova, S. & Howard-Jones, A. R. Biological formation of pyrroles: Nature's logic and enzymatic ... The biosynthesis of Prodigiosin involves the convergent coupling of three pyrrole type rings (labeled A, B, and C in figure 1) ... Oxidation of the resulting ring yields the final pyrrole ring C. Finally, these two pieces are stitched together in a ... Prodigiosin has recently received renewed attention for its wide range of biological activities, including activities as ...
  https://en.wikipedia.org/wiki/Prodigiosin
*  Difference between revisions of "OpenSourceMalaria:GSK Arylpyrrole Series" - OpenWetWare
Scifinder Search: 2,4,5-alkyl-1-aryl-pyrrole: 77552 hits, 905 biological studies: WO 2011127333 (A2) ... TCMDC Aryl pyrrole core InChi Key: LNROIXNEIZSESG-UHFFFAOYSA-N. * TCMDC Aryl pyrrole core InChi Key: LNROIXNEIZSESG-UHFFFAOYSA- ... Pyrrole core acid to amide: Amide Synthesis. Other known incidences of these molecules/this series. According to this paper, ... A number of these compounds and intermediates are available for biological testing from by request (contact information on the ...
  https://openwetware.org/wiki/?title=OpenSourceMalaria:GSK_Arylpyrrole_Series&diff=708788&oldid=597172
*  Difference between revisions of "OpenSourceMalaria:GSK Arylpyrrole Series" - OpenWetWare
Scifinder Search: 2,4,5-alkyl-1-aryl-pyrrole: 77552 hits, 905 biological studies: WO 2011127333 (A2) ... A number of these compounds and intermediates are available for biological testing from Todd group by request. ...
  https://openwetware.org/wiki/?title=OpenSourceMalaria:GSK_Arylpyrrole_Series&diff=565683&oldid=565682
*  Difference between revisions of "OpenSourceMalaria:GSK Arylpyrrole Series" - OpenWetWare
Scifinder Search: 2,4,5-alkyl-1-aryl-pyrrole: 77552 hits, 905 biological studies: WO 2011127333 (A2) ... Pyrrole core acid to amide: Amide Synthesis. Other known incidences of these molecules/this series. Related compounds are known ... A number of these compounds and intermediates are available for biological testing from Todd group by request. If you would ... The [1] side chain would target ester isosteres (see TCMDC-123812) but with greater biological stability. ...
  https://openwetware.org/wiki/?title=OpenSourceMalaria:GSK_Arylpyrrole_Series&diff=prev&oldid=597163
*  Double and#946;-alanine Substitutions Incorporated in 12-ring Pyrrole-Imidazole
Bando T, Sugiyama H (2006) Synthesis and biological properties of sequence-specific DNA-alkylating pyrrole-imidazole polyamides ... 2013) Effect of single pyrrole replacement with β-alanine on DNA binding affinity and sequence specificity of hairpin pyrrole/ ... Open circles denote pyrrole subunits, and filled (black) circles represent imidazoles in the simplified structure above. Dp=N, ... John WT, Eldon EB, Milan M, Dervan PB (1996) Extension of Sequence-Specific Recognition in the Minor Groove of DNA by Pyrrole- ...
  https://www.omicsonline.org/open-access/double-alanine-substitutions-incorporated-in-12ring-pyrroleimidazolepolyamides-for-lengthened-dna-minor-groove-recognition-2379-1764-1000175.php?aid=71916
*  Therapeutic Effect of Lecithinized Superoxide Dismutase against Colitis | Journal of Pharmacology and Experimental Therapeutics
2008) Applicability of new spin trap agent, 2-diphenylphosphinoyl-2-methyl-3,4-dihydro-2H-pyrrole N-oxide, in biological system ... LPS was from List Biological Laboratories Inc. (Campbell, CA). Alexa Fluor 488 goat anti-rabbit immunoglobulin G was purchased ...
  http://jpet.aspetjournals.org/content/328/1/152.long
*  Novel N-pyrrolylcarboxylic Acid Derivative As A Potential New Analgesic and Anti-inflammatory Drug - Novel N-pyrrolylcarboxylic...
18.Mohamed M S, Kamel R, Fatahala S S. (2011) New condensed pyrroles of potential biological interest. Syntheses and structure- ... synthesis and biological evaluation of hetero-aromatic moieties substituted pyrrole-2-carbonitrile derivatives as dipeptidyl ... The pyrrolic core is chosen due to its relatively low toxicity.11, 12 The pyrrole heterocycle is part of the chemical structure ... 19.Kim K J, Choi M J, Shin J, Kim M, Choi H. (2014) Synthesis, biological evaluation, and docking analysis of a novel family of ...
  https://openaccesspub.org/ijp/article/501
*  Facile Synthesis and Antimicrobial Evaluation of Some New Heterocyclic Compounds Incorporating a Biologically Active Sulfamoyl...
P. R. Kumar, S. Raju, P. Satish Goud et al., "Synthesis and biological evaluation of thiophene [3,2-b] pyrrole derivatives as ... The biological evaluation of the products 3a, 3c, 6, 7, 8b, 10, 15, 16, and 17 was carried out at the Medical Mycology ... M. S. A. El-Gaby, A. M. Gaber, A. A. Atalla, and K. A. Abd Al-Wahab, "Novel synthesis and antifungal activity of pyrrole and ... T. H. Maren, "Relatons between structure and biological activity of sulfonamides," Annual Review of Pharmacology and Toxicology ...
  https://www.hindawi.com/journals/tswj/2014/165495/
*  2PE1: Crystal Structure Of Human Phosphoinositide-Dependent Protein Kinase 1 (Pdk1) {2-Oxo-3-[1-(1h-Pyrrol-2-Yl)-Eth-(Z)...
1h-Pyrrol-2-Yl)ethyl]-2h-Indol-5-Yl}ureaGlycerin; Propane-1,2,3-triolGlycerolSulfate Ion ... Biological Unit for 2PE1: monomeric; determined by author. .unitschema-1{ background-image:url("/Structure/mmdb/mmdbimage.fcgi? ... 2PE1: Crystal Structure Of Human Phosphoinositide-Dependent Protein Kinase 1 (Pdk1) {2-Oxo-3-[1-(1h-Pyrrol-2-Yl)-Eth-(Z)- ... 1-{2-Oxo-3-[(1r)-1-(1h-Pyrrol-2-Yl)ethyl]-2h-Indol-5-Yl}urea. ...
  https://www.ncbi.nlm.nih.gov/Structure/pdb/2PE1
*  Lipidic furan, pyrrole, and thiophene compounds for treatment of cancer, neurological disorders, and fibrotic disorders -...
Buu-Hoi et al., "Thiophen derivatives of potential biological interest. Part IV. Tuberculostatic thiophen compounds" J. Chem. ... Synthesis of 2-(8Z,11Z-heptadecadlenyl)pyrrole (Scheme 3). *Step 1: A Mixture of pyrrole (2.0 g, 29.8 mmol) 8Z,11Z- ... In order to generate 2-alkylated pyrroles, pyrrole was acylated using zinc powder to afford 2-acylpyrroles. The 2-acylpyrroles ... In this paper, the authors disclosed the synthesis of 2-alkylated pyrroles and 3-alkylated pyrroles. The intermediates were ...
  http://www.freepatentsonline.com/9814694.html
*  KF/Al2O3: As a Solid Phase and Recyclable Basic Catalyst for Synthesis Mono and Bis Pyrimidine Derivatives
23] Bellina F., Rossi R., Synthesis and Biological Activity of Pyrrole, Pyrroline and Pyrrolidine Derivatives with Two Aryl ... 3-Dipolar Cycloaddition Route to Pyrrolines and Pyrroles from Imino Chlorosulfides, Tetrahedron Lett., 33: 6155-6158 (1992). ... 4-oxadiazoles Under Microwave-Assisted Solvent Free Conditions and Their Biological Activity, International Journal of ...
  http://www.ijcce.ac.ir/article_25189.html
*  A comparative study of the biological properties of Australian elapid venoms.
4-substituted 3-hydroxy-1h-pyrrole-2,5-dione deriv.... 16307769 - Isolation of a new l-amino acid oxidase from crotalus ... 4. The data show that information on venom biological properties can be used for differentiation of many species of Australian ... The non-procoagulant Australian venoms exhibited biological properties similar to other elapid venoms, while the procoagulant ...
  http://www.biomedsearch.com/nih/comparative-study-biological-properties-Australian/1981349.html
*  Homeopathy on the crossroads of traditional and integrative medicine in the Middle-East | SpringerLink
and its biological activities. Arch Pharm Res 30(8):927-931CrossRefPubMedGoogle Scholar ... El-Desouky SK, Kim KH, Ryu SY, Eweas AF, Gamal-Eldeen AM, Kim YK (2007) A new pyrrole alkaloid isolated from Arum palaestinum ...
  https://link.springer.com/article/10.1007%2Fs12682-014-0196-z
*  Gold(3+) bromide 2-oxo-2H-pyrrol-5-olate - 1,3-bis(2-methyl-2-butanyl)-2,3-didehydro-1H-3λ<sup>5</sup>-imidazole (1:2:1:1) |...
... bromide 2-oxo-2H-pyrrol-5-olate - 1,3-bis(2-methyl-2-butanyl)-2,3-didehydro-1H-3λ,sup>5. ... Biological Properties. Chemical Reactions. Chemical Safety Data. Drugs or Compounds in Development. Imaging Agents. ... o-2H-pyrrol-5-olat --1,3-bis(2-methyl-. 2-butanyl)-2,3-dide. hydro-1H-3λ5-imidazol (1:2:1:1) [German] [ACD/IUPAC Name] ... oxo-2H-pyrrol-5-ola. te - 1,3-bis(2-meth. yl-2-butanyl)-2,3-d. idehydro-1H-3λ5. -imidazole (1:2:1:1) [ACD/IUPAC Name] ...
  http://www.chemspider.com/Chemical-Structure.23558984.html?rid=f5bd117b-b00a-4936-9831-989970987f0f
*  Browse by Eprint ID - CaltechAUTHORS
2000) Targeting the Ets Binding Site of the HER2/neu Promoter with Pyrrole-Imidazole Polyamides. Journal of Biological ...
  https://authors.library.caltech.edu/view/ids/10741.html
*  Plus it
In the current study we provide the first documentation of the biological activity of members in this novel pyrrole carboxamide ... which was a positive ratio that was 40-fold less than that seen with the pyrrole carboxamide library. Furthermore, the pyrrole ... The pyrrole carboxamide library contained 41 building blocks for the R3 position; these included aliphatic as well as aromatic ... Arnold D, Foster C, Huryn D, Lazo J, Johnston P, and Wipf P (2007) Synthesis and biological activity of a focused library of ...
  http://jpet.aspetjournals.org/content/322/3/940
*  Anti-Inflammatory Effects of Protein Kinase Inhibitor Pyrrol Derivate
Nakvasina, Biological Membranes: Structural Organization, Functions, Modification by Physical and Chemical Agents, Voronezh ... Protein kinase inhibitor pyrrol derivate 1-(4-Cl-benzyl)-3-Cl-4-(CF3-fenylamino)-1Н-pyrrol-2,5-dione (MI-1) (Figure 1) has been ... Anti-Inflammatory Effects of Protein Kinase Inhibitor Pyrrol Derivate. Halyna M. Kuznietsova, Maryna S. Yena, Iryna P. Kotlyar ... Figure 1: 1-(4-Cl-benzyl)-3-Cl-4-(CF3-fenylamino)-1Н-pyrrol-2,5-dione (MI-1): structural formula. ...
  https://www.hindawi.com/journals/tswj/2016/2145753/
*  Hantzsch pyrrole synthesis - Wikipedia
Pyrroles are found in a variety of natural products with biological activity, so the synthesis of substituted pyrroles has ... 3-dicarbonylated pyrroles can be synthesized by a version of the Hantzsch Pyrrole Synthesis. These pyrroles are particularly ... Alternative methods for synthesizing pyrroles exist, such as the Knorr Pyrrole Synthesis and Paal-Knorr Synthesis. Below is one ... which also have biological significance. A library of substituted pyrrole analogs can be quickly produced by using continuous ...
  https://en.wikipedia.org/wiki/Hantzsch_pyrrole_synthesis
*  malaria research community | The Synaptic Leap
Here is a summary of the biological data obtained for the aryl pyrroles to date:. The team have been looking for patterns in ... First Set of Biological Results from the Third Round of Compounds. Published by Alice Williamson ... In late September, the commercial compounds, plus some of the synthetic targets (and analogues) were sent away for biological ... Read more about First Set of Biological Results from the Third Round of Compounds ...
  http://www.thesynapticleap.org/malaria/posts?page=1
*  Publications - Latvijas Organiskās sintēzes institūts
Structure, reactivity, biological applications and future perspectives . Химия гетероцикл.соед. 2002 (11), 1617-1618. ... Andersons A.; Simonyan S.; Lukevics E. Pyrrole-pyridine interconversions on the tungsten catalyst . Latvian J. Chem. 2002(2), ... Veretennikova N.; Skorova A.; Jansone D.; Lukevics E.; Leite L.; Melikyan G. Computer analysis of the biological activity of 2- ... Veretennikova N.; Skorova A.; Jansone D.; Lukevics E.; Leite L.; Melikyan G. Computer analysis of the biological activity of 4- ...
  http://www.osi.lv/en/publications/?op&gads=2002&pg=3&print=1
*  Faculty Full Profile
Intramolecular macrolactonization, photophysical and biological studies of new class of polycyclic pyrrole derivatives†. Org. ...
  http://vidyasagar.ac.in/Faculty/Profile/Print?fac_u_id=Fac-CHEM-164