*  Cap binding complex - Wikipedia
The 5' cap of eukaryotic messenger RNA is bound at all times by various Cap-binding complexes. In the nucleus freshly ... cap is bound by the mRNA decapping enzyme DCP2. A host of proteins accompany it including UPF1, UPF2, UPF3A, Dcp1, Dhh1, XRN1, ... transcribed mRNA molecules are bound on the 5' cap by the nuclear cap-binding complex of Cbc1/Cbc2 in yeast or CBP20/CBP80 in ... nuclear cap-binding protein complex at the US National Library of Medicine Medical Subject Headings (MeSH). ...
  https://en.wikipedia.org/wiki/Cap_binding_complex
*  Anti-eIF4E antibody [Y449] Recombinant (ab33768) | Abcam
Messanger RNA Cap Binding Protein eIF 4E antibody. *MGC111573 antibody. *mRNA cap binding protein antibody ... Phosphorylation increases the ability of the protein to bind to mRNA caps and to form the eIF4F complex. ... Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and ... Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1- ...
  https://www.abcam.com/eif4e-antibody-y449-ab33768.html
*  eIF4E (phospho S209)抗体[EP2151Y]|Abcam中国|Anti-eIF4E (phospho S209)抗体[EP2151Y]
Messanger RNA Cap Binding Protein eIF 4E antibody. *MGC111573 antibody. *mRNA cap binding protein antibody ... Phosphorylation increases the ability of the protein to bind to mRNA caps and to form the eIF4F complex. ... Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and ... Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1- ...
  http://www.abcam.cn/eif4e-phospho-s209-antibody-ep2151y-ab76256.html
*  Anti-eIF4E 抗体 (ab1126) | アブカム
Messanger RNA Cap Binding Protein eIF 4E antibody. *MGC111573 antibody. *mRNA cap binding protein antibody ... Phosphorylation increases the ability of the protein to bind to mRNA caps and to form the eIF4F complex. ... Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and ... Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1- ...
  http://www.abcam.co.jp/eif4e-antibody-ab1126.html
*  Developmental and Thermal Regulation of the Maize Heat Shock Protein, HSP101 | Plant Physiology
1987) Identification of two messenger RNA cap binding proteins in wheat germ: evidence that the 28-kDa subunit of eIF-4B and ... 1996) Isolation and characterization of the 102-kilodalton RNA-binding protein that binds to the 5′ and 3′ translational ... 1989) Polypeptide chain binding proteins: catalysts of protein folding and related processes in cells. Cell 59:591-601. ... RNA and protein from the embryo and endosperm were analyzed using northern and western analysis, respectively. Hsp101 protein ...
  http://www.plantphysiol.org/content/127/3/777.full
*  Protocols and Video Articles Authored by Brian J. Geiss
... virus capping enzyme with the Vaccinia virus VP39 protein bound to RNA suggests how the flavivirus capping enzyme may bind RNA ... end of the viral RNA using a fluorescence polarization-based RNA binding assay. We observed that the K(D) for RNA binding is ... The Flavivirus NS5 Protein is a True RNA Guanylyltransferase That Catalyzes a Two-step Reaction to Form the RNA Cap Structure ... Analysis of RNA Binding by the Dengue Virus NS5 RNA Capping Enzyme PloS One. 2011 , Pubmed ID: 22022449 Flaviviruses are small ...
  https://www.jove.com/author/Brian++J._Geiss
*  GEMIN5 Gene - GeneCards | GEMI5 Protein | GEMI5 Antibody
Protein Coding), Gem Nuclear Organelle Associated Protein 5, including: function, proteins, disorders, pathways, orthologs, and ... The RNA-binding protein Gemin5 binds directly to the ribosome and regulates global translation. (PMID: 27507887) Francisco- ... Binds to the 7-methylguanosine cap of RNA molecules (PubMed:19750007, PubMed:27834343, PubMed:27881600, PubMed:27881601, Ref.25 ... Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins. (PMID: 11714716) Gubitz AK … Dreyfuss G ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=GEMIN5
*  Post-translational regulation of rotavirus protein NSP1 expression in mammalian cells, Archives of Virology | 10.1007/s00705...
"Post-translational regulation of rotavirus protein NSP1 expression in mammalian cells, Archives of Virology" on DeepDyve, the ... RNA-binding and capping activities of proteins in rotavirus open cores. Patton, JT; Chen, D ... Rotavirus protein NSP3 (NS34) is bound to the 3′ end consensus sequence of viral mRNAs in infected cells ... Rotavirus RNA-binding protein NSP3 interacts with eIF4GI and evicts the poly(A) binding protein from eIF4F ...
  https://www.deepdyve.com/lp/springer_journal/post-translational-regulation-of-rotavirus-protein-nsp1-expression-in-ynxz1I2cNz
*  Thomas C Vanaman | Molecular & Cellular Biochemistry
"Structural analysis of the messenger RNA cap-binding protein. Presence of phosphate, sulfhydryl, and disulfide groups." The ... a peripheral membrane protein with covalently bound palmitic acid." The Journal of biological chemistry 262, 3 (1987): 1300-4. ... Specific probes for protein-binding domains." The Journal of biological chemistry 259, 24 (1984): 15414-24. [PubMed Link] , [ ... the vitamin D-dependent 28 kDa calcium binding protein." FEBS letters 297, 1-2 (1992): 127-31. [PubMed Link] , [ Full text ] ...
  https://biochemistry.med.uky.edu/users/vanaman
*  Improved methodology for the affinity isolation of human protein complexes expressed at near endogenous levels
Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation. Cell. 2009;138:328-339. [PMC free ... is required for the nuclear export of CBC bound to capped RNAs and the subsequent re-import of CBC along with importin-β (44,45 ... A nuclear cap binding protein complex involved in pre-mRNA splicing. Cell. 1994;78:657-668. [PubMed] ... A cap-binding protein complex mediating U snRNA export. Nature. 1995;376:709-712. [PubMed] ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC3605737/?lang=en-ca
*  Five-prime cap - Wikipedia
"Cocrystal Structure of the Messenger RNA 5′ Cap-Binding Protein (eIF4E) Bound to 7-methyl-GDP". Cell. 89 (6): 951-961. doi: ... Nuclear export of RNA is regulated by the cap binding complex (CBC), which binds exclusively to 7-methylguanylate-capped RNA. ... "ab initio capping mechanism." For capping with 7-methylguanylate, the capping enzyme complex (CEC) binds to RNA polymerase II ... this kind of mechanism ensures capping, as with polyadenylation). The enzymes for capping can only bind to RNA polymerase II, ...
  https://en.wikipedia.org/wiki/Five-prime_cap
*  NCBP2 Antibody
RNA cap binding. RNA 7-methylguanosine cap binding. RNA binding. mRNA binding. protein binding. snRNA binding. poly(A) RNA ... The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' ... nuclear cap binding protein subunit 2, 20kD; nuclear cap binding protein subunit 2, 20kDa; Nuclear cap-binding protein subunit ... The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC ...
  https://www.thermofisher.com/antibody/product/NCBP2-Antibody-Polyclonal/PA5-38625
*  PBAD promoter - Wikipedia
The two bound AraC proteins dimerize and cause looping of the DNA. The looping prevents binding of CAP and RNA Polymerase, ... Additionally, CAP binds to two CAP binding sites upstream of the I1 and I2 operators and helps activate the PBAD promoter. In ... The cyclic AMP receptor protein CAP binds between the PBAD and PC promoters, stimulating transcription of both when bound by ... The N-terminal arm of AraC interacts with its DNA binding domain, allowing two AraC proteins to bind to the O2 and I1 operator ...
  https://en.wikipedia.org/wiki/PBAD_promoter
*  OriGene - NCBP2 (NM 007362) cDNA Clone
Human nuclear cap binding protein subunit 2, 20kDa (NCBP2), transcript variant 1 available for purchase from OriGene - Your ... The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC ... Gene Summary: The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the ... Mouse nuclear cap binding protein subunit 2 (Ncbp2). $390. Next day. MG219175. Ncbp2 (GFP-tagged) - Mouse nuclear cap binding ...
  http://www.origene.com/human_cdna/NM_007362/SC115562.aspx
*  DEAD box - Wikipedia
Sonenberg N (1988). "Cap-binding proteins of eukaryotic messenger RNA: functions in initiation and control of translation". ... which makes the branch point recognition sequence of U2 available to bind the branch point sequence. Prp28 may have a role in ... Tanaka N, Schwer B (July 2005). "Characterization of the NTPase, RNA-binding, and RNA helicase activities of the DEAH-box ... but DEAD box proteins use ATP and DEAH does not. DEAD box proteins are considered to be RNA helicases and many have been found ...
  https://en.wikipedia.org/wiki/DEAD_box
*  anti-CBP80 antibody [N2], N-term | GeneTex
... nuclear cap binding protein subunit 1, 80kDa) for ICC/IF, IHC-P, WB. Anti-CBP80 pAb (GTX106328) is tested in Human samples. 100 ... The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes ... The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' ... nuclear cap-binding protein subunit 1 antibody, NCBP 80 kDa subunit antibody, "nuclear cap binding protein subunit 1, 80kDa ...
  http://www.genetex.com/CBP80-antibody-N2-N-term-GTX106328.html
*  Bacteria: Third RNA binding protein identified
This protein and the RNA molecules that bind to it represent a largely unresearched class of gene activity regulators in the ... Baffin Island - Disappearing ice caps. Giff Miller, geologist and paleoclima-tologist, is walking the margins of melting ... Bacteria: Third RNA binding protein identified. 18.10.2016. Small regulatory RNA molecules are vital for salmonella and other ... The structures of the different regulatory RNA molecules are shown left, their preferred protein binding partners on the right ...
  http://www.innovations-report.com/html/reports/life-sciences/bacteria-third-rna-binding-protein-identified.html
*  Capping enzyme - Wikipedia
Wen, Y; Yue, Z; Shatkin, AJ (Oct 13, 1998). "Mammalian capping enzyme binds RNA and uses protein tyrosine phosphatase mechanism ... domain and a C-terminal oligonucleotide binding (OB) domain. The NTase domain, conserved in capping enzymes, DNA and RNA ... When this complex of RNA polymerase II and the capping enzymes is achieved, the capping enzymes are able to add the cap to the ... cap is therefore specific to RNAs synthesized by this polymerase rather than those synthesized by RNA polymerase I or RNA ...
  https://en.wikipedia.org/wiki/Capping_enzyme
*  Impact of DNA3′pp5′G capping on repair reactions at DNA 3′ ends | PNAS
2011) Cap and cap-binding proteins in the control of gene expression. Wiley Interdiscip Rev RNA 2(2):277-298. ... Because the available crystal structures of Schizosaccharomyces pombe and human aprataxin with AMP bound in the active site are ... G cap. DNA capping blocks 3′ end-resection and healing, while permitting DNA synthesis from the cap guanosine-3′-OH primer by ... Protein concentrations were determined by the BioRad dye binding method with BSA as the standard. E. coli exonucleases I and ...
  http://www.pnas.org/content/111/31/11317
*  After fertilization of sea urchin eggs, eIF4G is post-translationally modified and associated with the cap-binding protein...
... eIF4G binds independently of eIF4E to a large secondary structure element within the RNA called the internal ribosome entry ... Protein A Sepharose beads with anti-SgIF4G but without proteins and protein A Sepharose beads with proteins but without anti- ... Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo. Mol. ... Repression of cap-dependent translation by 4E-binding protein 1, competition with p220 for binding to eukaryotic initiation ...
  http://jcs.biologists.org/content/120/3/425
*  Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome.
The eIF4F complex is composed of the 5′ cap binding protein eIF4E, a scaffolding protein eIF4G, and the RNA helicase eIF4A 23. ... Alternatively, H1a bound, and constitutively active mGluR5 which drives total protein synthesis rates (Fig. 3) 20 could elevate ... 0/Carrier Proteins; 0/Fmr1 protein, mouse; 0/Grm5 protein, mouse; 0/Grm5 protein, rat; 0/Homer protein; 0/Peptides; 0/Protein ... which in turn phosphorylates the cap-binding protein eIF4E (S209) 23. ERK also phosphorylates eIF4E binding protein (4EBP) at ...
  http://www.biomedsearch.com/nih/Disrupted-Homer-scaffolds-mediate-abnormal/22267161.html
*  Nuclear cap-binding protein complex - Wikipedia
Nuclear cap-binding protein complex is a RNA-binding protein which binds to the 5' cap of pre-mRNA. The cap and nuclear cap- ... When RNA is exported to the cytoplasm the nuclear cap-binding protein complex is replaced by cytoplasmic cap binding complex. ... Human nuclear cap-binding protein complex plays important role in the maturation of pre-mRNA and uracil-rich small nuclear RNA ... Human nuclear cap-binding protein complex shows the large subunit, CBC80 consists of 757 amino acid residues. Its secondary ...
  https://en.wikipedia.org/wiki/Nuclear_cap-binding_protein_complex
*  KH domain protein RCF3 is a tissue-biased regulator of the plant miRNA biogenesis cofactor HYL1 | PNAS
... the nuclear cap-binding complex (CBC), the double-stranded RNA-binding protein HYPONASTIC LEAVES1 (HYL1), and the HYL1 ... binding proteins (PCBPs) and are predicted to bind RNA (20⇓-22). RCF3 contributes to tolerance against various stresses, ... 2015) The RNA-binding protein HOS5 and serine/arginine-rich proteins RS40 and RS41 participate in miRNA biogenesis in ... 2002) Genome analysis: RNA recognition motif (RRM) and K homology (KH) domain RNA-binding proteins from the flowering plant ...
  http://www.pnas.org/content/112/45/14096
*  Loss of Protein Arginine Methyltransferase 8 Alters Synapse Composition and Function, Resulting in Behavioral Defects | Journal...
We also examined levels of the RNA binding protein FMRP and a number of cap-dependent translation regulators as these proteins ... 2008) Identification of proteins interacting with protein arginine methyltransferase 8: the Ewing sarcoma (EWS) protein binds ... PRMT8 can physically interact with a number of RNA binding proteins, and numerous RNA binding proteins, such as FMRP, are ... Despite the requirement of this protein complex for global cellular protein synthesis, alterations in cap binding complex ...
  http://www.jneurosci.org/content/37/36/8655?rss=1
*  Karla M Neugebauer, PhD > Biological & Biomedical Sciences | Yale...
Specialized Terms: pre-mRNA splicing, transcription, gene architecture, SR proteins, cap-binding complex, RNA-protein ... Illustration of the nucleus and cytoplasm of a eukaryotic cell containing nonmembrane-bound cellular bodies, such as nucleoli, ... The RNA-binding landscapes of two SR proteins reveal unique functions and binding to diverse RNA classes. Änkö, M-L., M. Müller ... The RNA-binding landscapes of two SR proteins reveal unique functions and binding to diverse RNA classes. Genome Biology 13: ...
  http://medicine.yale.edu/bbs/people/karla_neugebauer-2.profile