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*  Cap binding complex - Wikipedia
The 5' cap of eukaryotic messenger RNA is bound at all times by various Cap-binding complexes. In the nucleus freshly ... cap is bound by the mRNA decapping enzyme DCP2. A host of proteins accompany it including UPF1, UPF2, UPF3A, Dcp1, Dhh1, XRN1, ... transcribed mRNA molecules are bound on the 5' cap by the nuclear cap-binding complex of Cbc1/Cbc2 in yeast or CBP20/CBP80 in ... nuclear cap-binding protein complex at the US National Library of Medicine Medical Subject Headings (MeSH). ...
  https://en.wikipedia.org/wiki/Cap_binding_complex
*  Anti-eIF4E antibody [Y449] Recombinant (ab33768) | Abcam
Messanger RNA Cap Binding Protein eIF 4E antibody. *MGC111573 antibody. *mRNA cap binding protein antibody ... Phosphorylation increases the ability of the protein to bind to mRNA caps and to form the eIF4F complex. ... Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and ... Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1- ...
  https://www.abcam.com/eif4e-antibody-y449-ab33768.html
*  Insights from a Paradigm Shift: How the Poly(A)-Binding Protein Brings Translating mRNAs Full Circle
K. S. Browning, S. R. Lax, and J. M. Ravel, "Identification of two messenger RNA cap binding proteins in wheat germ. Evidence ... S. Cheng and D. R. Gallie, "eIF4G, eIFiso4G, and eIF4B bind the poly(A)-binding protein through overlapping sites within the ... U. Kühn and T. Pieler, "XenopusPoly(A) binding protein: functional domains in RNA binding and protein-protein interaction," ... Y. V. Svitkin, V. M. Evdokimova, A. Brasey et al., "General RNA-binding proteins have a function in poly(A)-binding protein- ...
  https://www.hindawi.com/journals/njos/2014/873084/ref/
*  eIF4E (phospho S209)抗体[EP2151Y]|Abcam中国|Anti-eIF4E (phospho S209)抗体[EP2151Y]
Messanger RNA Cap Binding Protein eIF 4E antibody. *MGC111573 antibody. *mRNA cap binding protein antibody ... Phosphorylation increases the ability of the protein to bind to mRNA caps and to form the eIF4F complex. ... Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and ... Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1- ...
  http://www.abcam.cn/eif4e-phospho-s209-antibody-ep2151y-ab76256.html
*  Anti-eIF4E 抗体 (ab1126) | アブカム
Messanger RNA Cap Binding Protein eIF 4E antibody. *MGC111573 antibody. *mRNA cap binding protein antibody ... Phosphorylation increases the ability of the protein to bind to mRNA caps and to form the eIF4F complex. ... Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and ... Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1- ...
  http://www.abcam.co.jp/eif4e-antibody-ab1126.html
*  eIF4E重组抗体[EP2151Y] eIF4E抗体(ab76256)| Abcam中国
Messanger RNA Cap Binding Protein eIF 4E antibody. *MGC111573 antibody. *mRNA cap binding protein antibody ... Phosphorylation increases the ability of the protein to bind to mRNA caps and to form the eIF4F complex. ... Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and ... Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1- ...
  https://www.abcam.cn/eif4e-phospho-s209-antibody-ep2151y-ab76256.html
*  Developmental and Thermal Regulation of the Maize Heat Shock Protein, HSP101 | Plant Physiology
1987) Identification of two messenger RNA cap binding proteins in wheat germ: evidence that the 28-kDa subunit of eIF-4B and ... 1996) Isolation and characterization of the 102-kilodalton RNA-binding protein that binds to the 5′ and 3′ translational ... 1989) Polypeptide chain binding proteins: catalysts of protein folding and related processes in cells. Cell 59:591-601. ... RNA and protein from the embryo and endosperm were analyzed using northern and western analysis, respectively. Hsp101 protein ...
  http://www.plantphysiol.org/content/127/3/777.full
*  LSM1 Gene - GeneCards | LSM1 Protein | LSM1 Antibody
Protein Coding), LSM1 Homolog, MRNA Degradation Associated, including: function, proteins, disorders, pathways, orthologs, and ... This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind ... Gene Ontology (GO) annotations related to this gene include RNA cap binding. ... Protein Symbol:. O15116-LSM1_HUMAN. Recommended name:. U6 snRNA-associated Sm-like protein LSm1. Protein Accession:. O15116. ...
  https://www.genecards.org/cgi-bin/carddisp.pl?gene=LSM1
*  Protocols and Video Articles Authored by Brian J. Geiss
... virus capping enzyme with the Vaccinia virus VP39 protein bound to RNA suggests how the flavivirus capping enzyme may bind RNA ... end of the viral RNA using a fluorescence polarization-based RNA binding assay. We observed that the K(D) for RNA binding is ... The Flavivirus NS5 Protein is a True RNA Guanylyltransferase That Catalyzes a Two-step Reaction to Form the RNA Cap Structure ... Analysis of RNA Binding by the Dengue Virus NS5 RNA Capping Enzyme PloS One. 2011 , Pubmed ID: 22022449 Flaviviruses are small ...
  https://www.jove.com/author/Brian++J._Geiss
*  GEMIN5 Gene - GeneCards | GEMI5 Protein | GEMI5 Antibody
Protein Coding), Gem Nuclear Organelle Associated Protein 5, including: function, proteins, disorders, pathways, orthologs, and ... The RNA-binding protein Gemin5 binds directly to the ribosome and regulates global translation. (PMID: 27507887) Francisco- ... Binds to the 7-methylguanosine cap of RNA molecules (PubMed:19750007, PubMed:27834343, PubMed:27881600, PubMed:27881601, Ref.25 ... Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins. (PMID: 11714716) Gubitz AK … Dreyfuss G ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=GEMIN5
*  Post-translational regulation of rotavirus protein NSP1 expression in mammalian cells, Archives of Virology | 10.1007/s00705...
"Post-translational regulation of rotavirus protein NSP1 expression in mammalian cells, Archives of Virology" on DeepDyve, the ... RNA-binding and capping activities of proteins in rotavirus open cores. Patton, JT; Chen, D ... Rotavirus protein NSP3 (NS34) is bound to the 3′ end consensus sequence of viral mRNAs in infected cells ... Rotavirus RNA-binding protein NSP3 interacts with eIF4GI and evicts the poly(A) binding protein from eIF4F ...
  https://www.deepdyve.com/lp/springer_journal/post-translational-regulation-of-rotavirus-protein-nsp1-expression-in-ynxz1I2cNz
*  Thomas C Vanaman | Molecular & Cellular Biochemistry
"Structural analysis of the messenger RNA cap-binding protein. Presence of phosphate, sulfhydryl, and disulfide groups." The ... a peripheral membrane protein with covalently bound palmitic acid." The Journal of biological chemistry 262, 3 (1987): 1300-4. ... Specific probes for protein-binding domains." The Journal of biological chemistry 259, 24 (1984): 15414-24. [PubMed Link] , [ ... the vitamin D-dependent 28 kDa calcium binding protein." FEBS letters 297, 1-2 (1992): 127-31. [PubMed Link] , [ Full text ] ...
  https://biochemistry.med.uky.edu/users/vanaman
*  Improved methodology for the affinity isolation of human protein complexes expressed at near endogenous levels
Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation. Cell. 2009;138:328-339. [PMC free ... is required for the nuclear export of CBC bound to capped RNAs and the subsequent re-import of CBC along with importin-β (44,45 ... A nuclear cap binding protein complex involved in pre-mRNA splicing. Cell. 1994;78:657-668. [PubMed] ... A cap-binding protein complex mediating U snRNA export. Nature. 1995;376:709-712. [PubMed] ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC3605737/?lang=en-ca
*  Five-prime cap - Wikipedia
"Cocrystal Structure of the Messenger RNA 5′ Cap-Binding Protein (eIF4E) Bound to 7-methyl-GDP". Cell. 89 (6): 951-961. doi: ... Nuclear export of RNA is regulated by the cap binding complex (CBC), which binds exclusively to 7-methylguanylate-capped RNA. ... "ab initio capping mechanism." For capping with 7-methylguanylate, the capping enzyme complex (CEC) binds to RNA polymerase II ... this kind of mechanism ensures capping, as with polyadenylation). The enzymes for capping can only bind to RNA polymerase II, ...
  https://en.wikipedia.org/wiki/Five-prime_cap
*  Translation initiation mediated by RNA looping | PNAS
In the cap-dependent translation, eIF4G is loaded onto mRNA as a protein complex with eIF4E (cap-binding protein) and eIF4A ( ... binding protein (PABP) that binds to the poly(A) tail. Moreover, eIF4G plays pivotal roles in IRES-dependent translation of ... When A-capped RNAs containing MS2-binding sites were introduced into HEK293T cells expressing MS2-4GMC protein, expression of ... cap structure and 3′-poly(A) via an RNA-protein complex consisting of cap-eIF4E-eIF4G-PABP-poly(A) preferentially facilitates ...
  http://www.pnas.org/content/112/4/1041
*  DEAD box - Wikipedia
Sonenberg N (1988). "Cap-binding proteins of eukaryotic messenger RNA: functions in initiation and control of translation". ... which makes the branch point recognition sequence of U2 available to bind the branch point sequence. Prp28 may have a role in ... Tanaka N, Schwer B (July 2005). "Characterization of the NTPase, RNA-binding, and RNA helicase activities of the DEAH-box ... but DEAD box proteins use ATP and DEAH does not. DEAD box proteins are considered to be RNA helicases and many have been found ...
  https://en.wikipedia.org/wiki/DEAD_box
*  NCBP2 Antibody
RNA cap binding. RNA 7-methylguanosine cap binding. RNA binding. mRNA binding. protein binding. snRNA binding. poly(A) RNA ... The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' ... nuclear cap binding protein subunit 2, 20kD; nuclear cap binding protein subunit 2, 20kDa; Nuclear cap-binding protein subunit ... The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC ...
  https://www.thermofisher.com/antibody/product/NCBP2-Antibody-Polyclonal/PA5-38625
*  PBAD promoter - Wikipedia
The two bound AraC proteins dimerize and cause looping of the DNA. The looping prevents binding of CAP and RNA Polymerase, ... Additionally, CAP binds to two CAP binding sites upstream of the I1 and I2 operators and helps activate the PBAD promoter. In ... The cyclic AMP receptor protein CAP binds between the PBAD and PC promoters, stimulating transcription of both when bound by ... The N-terminal arm of AraC interacts with its DNA binding domain, allowing two AraC proteins to bind to the O2 and I1 operator ...
  https://en.wikipedia.org/wiki/PBAD_promoter
*  Capping enzyme - Wikipedia
Wen, Y; Yue, Z; Shatkin, AJ (Oct 13, 1998). "Mammalian capping enzyme binds RNA and uses protein tyrosine phosphatase mechanism ... domain and a C-terminal oligonucleotide binding (OB) domain. The NTase domain, conserved in capping enzymes, DNA and RNA ... When this complex of RNA polymerase II and the capping enzymes is achieved, the capping enzymes are able to add the cap to the ... cap is therefore specific to RNAs synthesized by this polymerase rather than those synthesized by RNA polymerase I or RNA ...
  https://en.wikipedia.org/wiki/Capping_enzyme
*  OriGene - NCBP2 (NM 007362) cDNA Clone
Human nuclear cap binding protein subunit 2, 20kDa (NCBP2), transcript variant 1 available for purchase from OriGene - Your ... The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC ... Gene Summary: The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the ... Mouse nuclear cap binding protein subunit 2 (Ncbp2). $390. Next day. MG219175. Ncbp2 (GFP-tagged) - Mouse nuclear cap binding ...
  http://www.origene.com/human_cdna/NM_007362/SC115562.aspx
*  Structural dynamics of the lac repressor-DNA complex revealed by a multiscale simulation | PNAS
... which includes binding sites for RNA polymerase and the activator protein CAP (1). ... where the protein binds disjoint DNA segments (Fig. 1c ), is indeed altered when the protein is bound to a continuous DNA loop ... 1), deposited to the Protein Data Bank (ID code 1Z04), was built from several Protein Data Bank structures; protein or DNA ... The lac repressor (LacI) is a celebrated DNA-binding protein that regulates the function of the lac operon (1), a set of genes ...
  http://www.pnas.org/content/102/19/6783.full
*  Nuclear cap-binding protein complex - Wikipedia
Nuclear cap-binding protein complex is a RNA-binding protein which binds to the 5' cap of pre-mRNA. The cap and nuclear cap- ... When RNA is exported to the cytoplasm the nuclear cap-binding protein complex is replaced by cytoplasmic cap binding complex. ... Human nuclear cap-binding protein complex plays important role in the maturation of pre-mRNA and uracil-rich small nuclear RNA ... Human nuclear cap-binding protein complex shows the large subunit, CBC80 consists of 757 amino acid residues. Its secondary ...
  https://en.wikipedia.org/wiki/Nuclear_cap-binding_protein_complex
*  NCBP2 - Nuclear cap-binding protein subunit 2 - Homo sapiens (Human) - NCBP2 gene & protein
In the CBC complex, NCBP2/CBP20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires NCBP1/CBP80 to stabilize the ... The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in ... before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of ... movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. ...
  https://www.uniprot.org/uniprot/P52298&format=html
*  anti-CBP80 antibody [N2], N-term | GeneTex
... nuclear cap binding protein subunit 1, 80kDa) for ICC/IF, IHC-P, WB. Anti-CBP80 pAb (GTX106328) is tested in Human samples. 100 ... The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes ... The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' ... nuclear cap-binding protein subunit 1 antibody, NCBP 80 kDa subunit antibody, "nuclear cap binding protein subunit 1, 80kDa ...
  http://www.genetex.com/CBP80-antibody-N2-N-term-GTX106328.html
*  Eukaryotic initiation factor 4F - Wikipedia
The eIF4F complex is composed of three non-identical subunits: the DEAD-box RNA helicase eIF4A, the cap-binding protein eIF4E, ... Eukaryotic initiation factor 4F (eIF4F) is a heterotrimeric protein complex that binds the 5' cap of messenger RNAs (mRNAs) to ... via eIF4A's RNA helicase activity. The eIF4F proteins interact with a number of different binding partners, and there are ... eIF4E binds the m7G 5' cap and the eIF4G scaffold, connecting the mRNA 5' terminus to a hub of other initiation factors and ...
  https://en.wikipedia.org/wiki/Eukaryotic_initiation_factor_4F