*  KorA binds its operator binding site. (A) OA* with the | Open-i
A) OA* with the central 12-bp consensus operator sequence in red and green. (In OA the BrU bases are replaced by T.) The ... DNA-Binding Proteins/chemistry*/metabolism. *Operator Regions, Genetic*. *Plasmids/genetics*. *Repressor Proteins/chemistry*/ ... Figure 4: KorA binds its operator binding site. (A) OA* with the central 12-bp consensus operator sequence in red and green. ( ... Figure 4: KorA binds its operator binding site. (A) OA* with the central 12-bp consensus operator sequence in red and green. ( ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2665229_gkp044f4&req=4
*  NAVER Academic | ArgR-dependent Repression of Arginine and Histidine Transport Genes in Escherichia coli K-12
... of P hisJ by inhibition of RNA polymerase binding appears to occur through topological changes of the promoter region. ... Here we characterize the repressible Eσ 70 P artJ, P artP and P hisJ promoters and demonstrate that the cognate operators ... The organization of the ARG boxes and promoter elements in the control regions of the uptake genes is distinct from that of the ... Determination of the energy landscape of the ArgR-operator contacts by missing contact probing and mutant studies indicated ...
  http://academic.naver.com/article.naver?doc_id=146506156
*  A novel DNA-binding protein modulating methicillin resistance in staphylococcus aureus - Zurich Open Repository and Archive
RESULTS: Analysis of proteins binding to a DNA fragment containing the mec operator region identified a novel, putative helix- ... Nonpolar deletion of SA1665, in heterogeneously methicillin resistant S. aureus (MRSA) of different genetic backgrounds, ... RESULTS: Analysis of proteins binding to a DNA fragment containing the mec operator region identified a novel, putative helix- ... Although SA1665 bound to the mecA promoter region, it had no apparent influence on mecA transcription or translation, ...
  http://www.zora.uzh.ch/id/eprint/17908/
*  USDA APHIS | 'Am I Regulated?' Process
Element type (e.g., operators, promoters, origins of replication, terminators, ribosome binding regions); ... Brief description of genetic element's function. If your letter of inquiry contains confidential business information (CBI), ... Description of vector or vector agent used to induce genetic change in the organism (e.g., biolistic delivery, disarmed ... Description of intended genetic change in final product (e.g., insertion, deletion, substitution). ...
  https://www.aphis.usda.gov/aphis/ourfocus/biotechnology/SA_Regulations/Am+I+Regulated
*  Volume 31 Issue 12 | Optical Engineering
Three feature analysis tools-a genetic algorithm, a branch-and-bound algorithm, and a new class overlap region partitioning ... The solution is based on a singular value decomposition of the forward operator matrix. A priori information can be ... The problem of region segmentation is examined and a new algorithm for maximum a posteriori (MAP) segmentation is introduced. ... The observed image is modeled as a composite of two processes: a high-level process that describes the various regions in the ...
  https://www.spiedigitallibrary.org/journals/optical-engineering/volume-31/issue-12
*  Signals & sensors
Genetic operators can bind sensors to different pathways to respond to alternative contexts. Responding to a set of situational ... addressable binding regions, protein active sites and signal structures which can then be reused through the mutation genetic ... genetic operators. In general the association of environmental signals, sensors and actions is under the control of genetic ... Genetic operators. This page reviews the inhibiting effect of the value delivery system on the expression of new phenotypic ...
  http://robsstrategystudio.org/awfcpiss.htm
*  cis-acting locus - oi
A genetic region affecting the activity of genes on that same DNA molecule. Cis-acting loci generally do not encode proteins, ... but rather serve as attachment sites for DNA-binding proteins. Enhancers, operators, and promoters are examples of cis-acting ...
  http://oxfordindex.oup.com/view/10.1093/oi/authority.20110803095613471
*  Sequences of DNA probes used for defining the sequence | Open-i
Sequences of DNA probes used for defining the sequence requirements for high-affinity binding by EbfC. All were based upon the ... Binding Sites. *Conserved Sequence. *Molecular Sequence Data. *Nucleic Acid Conformation. *Operator Regions, Genetic ... Two high-affinity EbfC-binding sites are located immediately 5' of B. burgdorferi erp transcriptional promoters, and binding of ... Two high-affinity EbfC-binding sites are located immediately 5' of B. burgdorferi erp transcriptional promoters, and binding of ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2665219_gkp027f1&req=4
*  Polyepitope carrier protein - Patent # 6855321 - PatentGenius
... coli operator region (EPO Publ. No. 267 85 1).. In addition to a functioning promoter sequence, an efficient ribosome binding ... In Genetic Engineering: Proceedings of the International Symposium on Genetic Engineering (eds. H.W. Boyer and S. Nicosia); ... The operator permits negative regulated (inducible) transcription, as a gene repressor proteinmay bind the operator and thereby ... This transcription initiation region usually includes an RNA polymerase binding site and atranscription initiation site. A ...
  http://www.patentgenius.com/patent/6855321.html
*  SPIDR: small-molecule peptide-influenced drug repurposing | SpringerLink
The genetic algorithm-based search procedure, GAMPMS, was used to heuristically explore the ligand binding domain of the α3β2- ... are more likely to correlate to the peptide signatures when associating with the sizable binding region of nAChR. ... The mutation operator provided an amino acid an equal chance of being substituted for any other amino acids within the defined ... The estimated binding free energy of α-CTx MII was − 12.38 kcal/mol compared to the ∆Gbind of the top ten mutants ranging from ...
  https://link.springer.com/article/10.1186/s12859-018-2153-y
*  CH391L/S13/Refactoring Operons - OpenWetWare
... it with synthetic genetic parts and circuits" [2]. The result of this process is is a simplified genetic system whose DNA ... Expression levels of each operon are controlled by synthetic ribosome binding sites (RBSs). The resulting gene cluster is a set ... Prokaryotic genes associated with a specific function are often grouped together in contiguous regions of the genome known as ... operators, mRNA secondary structure, etc. [2]. Bioinformatics approaches are then used to identify and remove putative ...
  https://openwetware.org/wiki/?title=CH391L/S13/Refactoring_Operons&oldid=691677
*  7CFR Restrictions on the Introduction of Regulated Articles. As revised May PDF
... operators, promoters, origins of replication, terminators, and ribosome binding regions). The genetic material added to a ... GENETIC ENGINEERING - PLASMIDS, EPISOMES GENETIC ENGINEERING - PLASMIDS, EPISOMES Genetic Engineering Genetic engineering is a ... Genetic Engineering. Restriction endonuclease. 1. Enzymes Chapter 10. Genetic Engineering Tools and Techniques 1. Enzymes 2. 3 ... Genetic engineering. The genetic modification of organisms by recombinant DNA techniques. Inspector. Any employee of the Animal ...
  http://docplayer.net/256588-7cfr340-340-0-restrictions-on-the-introduction-of-regulated-articles-as-revised-may-1997.html
*  CH391L/S13/Refactoring Operons - OpenWetWare
This genetic separation allows for expression to remain tightly off in the absence of a controller, and also allows one ... The first step of the design process is to remove regions of noncoding DNA and any regulatory genes. Essential genes are then ... Expression levels of each operon are controlled by synthetic ribosome binding sites (RBSs). The resulting gene cluster is a set ... operators, mRNA secondary structure, pause sites, methylation sites, and codon regulation [2]. Bioinformatics approaches are ...
  https://openwetware.org/wiki/?title=CH391L/S13/Refactoring_Operons&oldid=691503
*  Gene structure - Wikipedia
The 5' UTR binds the ribosome, which translates the protein-coding region into a string of amino acids that fold to form the ... The operator sequence next to the promoter is the main regulatory element in prokaryotes. Repressor proteins bound to the ... Jacob, F.; Monod, J. (1961-06-01). "Genetic regulatory mechanisms in the synthesis of proteins". Journal of Molecular Biology. ... The proximal promoter region binds transcription factors that modify the affinity of the core promoter for RNA polymerase. ...
  https://en.wikipedia.org/wiki/Gene_structure
*  Difference between revisions of "CH391L/S13/Refactoring Operons" - OpenWetWare
it with synthetic genetic parts and circuits. ' ,cite,Temme2012,/cite,. The result of this process is is a simplified genetic ... The first step of the design process is to remove regions of noncoding DNA and any known regulatory genes. Essential genes are ... Expression levels of each operon are controlled by synthetic ribosome binding sites (RBSs). The resulting gene cluster is a set ... internal regulatory elements i.e. promoters, operators, mRNA secondary structure, pause sites, methylation sites, and codon ...
  https://openwetware.org/wiki/?title=CH391L/S13/Refactoring_Operons&diff=693170&oldid=691476
*  NetLogo Models Library: Synthetic Biology - Genetic Switch
... is not bound to the lac operator region. The probability of an RNA polymerase binding to the promoter and starting ... ONPG molecules bind to LacI repressor proteins that changes the shape of LacIs preventing them binding to the operator region ... They bind to the operator region (see below) of the DNA and do not let RNAP to pass along the gene, thus stopping protein ... These complexes cannot bind to the operator region of the DNA.. *ONPG molecules - These are grey pentagons in the model. [ONPG ...
  http://ccl.northwestern.edu/netlogo/models/SyntheticBiology-GeneticSwitch
*  Patent US6750056 - Metal binding proteins and associated methods - Google Patents
The metal binding proteins include have amino acid sequences analogous to at least one metal binding protein, and conservative ... Also provided are the associated nucleic acid sequences encoding metal binding proteins. ... Metal binding proteins, associated compositions and methods for their production and use are disclosed. ... such as the functional or metal binding regions of the metal binding protein isomers of the present invention. ...
  http://www.google.com/patents/US6750056?dq=6289460
*  Subspace trust-region algorithm with conic model for unconstrained optimization
In this new algorithm, the subspace technique is used in the trust region subproblem with conic model, and the dogleg method is ... A global error bound via the SQP method for constrained optimization problem. Journal of Industrial & Management Optimization, ... A hybrid method combining genetic algorithm and Hooke-Jeeves method for constrained global optimization. Journal of Industrial ... Global convergence of an inexact operator splitting method for monotone variational inequalities. Journal of Industrial & ...
  http://aimsciences.org/article/doi/10.3934/naco.2013.3.223
*  Biotechnology Glossary J-Q
Operator The region of DNA that is upstream from a gene or genes and to which one or more regulatory proteins (repressor or ... activator) bind to control the expression of the gene(s).. Operon A functionally integrated genetic unit for the control of ... Nucleus A dense protoplasmic membrane-bound region of a eukaryotic cell that contains the chromosomes, separated from the ... Kartagener's syndrome A genetic disorder in which the heart and other internal organs are on the opposite side of the body to ...
  http://www.bioscreening.net/glossary/biotechnology-glossary-j-q/
*  Structure of the C‐terminal domain of Tup1, a corepressor of transcription in yeast | The EMBO Journal
For example, in the regulation of mating‐type genes, the DNA‐binding protein, Matα2, binds with MCM1 to operator sites upstream ... The conserved region on the top surface of the propeller is also present in Groucho/TLE, but somewhat smaller. In addition, the ... Srb10, Srb11, Sin4 and Rox3 were each identified in genetic screens as being involved in repression by the Tup1‐Ssn6 complex ( ... A universal feature of Tup1‐Ssn6‐mediated repression is that sequence‐specific DNA‐binding proteins must bind upstream of the ...
  http://emboj.embopress.org/content/19/12/3016
*  Synechocystis - Wikipedia
... all of which repress gene expression by a repressor molecule that binds the gene operator and blocks RNAP progression. Progress ... Type I promoters consists of a consensus -35 and -10 region (Pribnow box) upstream of the gene start site. Heidorn et al. 2011 ... PCC6803 is considered a model organism, yet there exist few synthetic parts that can be used for genetic engineering. As ... In E. coli, a repressor binds the DNA operon and dislodges RNAP due to the loosely bound beta clamp, whereas in Synechocystis, ...
  https://en.wikipedia.org/wiki/Synechocystis
*  List of genetic algorithm applications - Wikipedia
"Genetic Programming for Estimation of Heat Flux between the Atmosphere and Sea Ice in Polar Regions". Auffarth, B. (2010). ... Calculation of bound states and local-density approximations Chemical kinetics (gas and solid phases) Climatology: Modelling ... Clustering by a Genetic Algorithm with Biased Mutation Operator. WCCI CEC. IEEE, July 18-23, 2010. http://citeseerx.ist.psu.edu ... an article on genetic particle models Hill T, Lundgren A, Fredriksson R, Schiöth HB (2005). "Genetic algorithm for large-scale ...
  https://en.wikipedia.org/wiki/List_of_genetic_algorithm_applications
*  Unrelated toxin-antitoxin systems cooperate to induce persistence | Journal of The Royal Society Interface
... autorepresses transcription by binding to one or more operators in the promoter region. The toxin enhances repression, in some ... This can be seen in Bacillus subtilis genetic competence, spore formation, and swimming or chaining, as well as the persistent ... An eightfold decrease in β moves the system from Region 3 to Region 29, which is similar to Region 21 save that active ... and hence binds with twice the affinity, or 2/KH. The fourth term assumes that the complex D binds the operator with the same ...
  http://rsif.royalsocietypublishing.org/content/12/108/20150130
*  Conservation of Genetic Information Between Regulatory Proteins and their Cognate DNA/RNA Binding Sites: A Basis for Site...
... operators and response elements) has been observed and is proposed as a basis for site-specific recognition. We present anal ... Conservation of information between prokaryotic and eukaryotic regulatory proteins and their cognate binding sites on DNA and ... Nucleotide sequences similar to this operator are found within the Ala tRNA synthetase protein binding regions of the Ala tRNA ... Conservation of Genetic Information Between Regulatory Proteins and their Cognate DNA/RNA Binding Sites: A Basis for Site- ...
  http://www.jbsdonline.com/conservation-genetic-information-between-regulatory-proteins-and-their-cognate-dna-rna-binding-sites-basis-site-specific-protein-nucleotide-recognition-and-origin-of-genetic-code-p11604.html
*  Messenger RNA - Wikipedia
... and their coding sequence is grouped and regulated together in a regulatory region, containing a promoter and an operator. Most ... Poliovirus mRNA uses a cloverleaf section towards its 5' end to bind PCBP2, which binds poly(A)-binding protein, forming the ... Genetic variants in 3' UTR have also been implicated in disease susceptibility because of the change in RNA structure and ... and three prime untranslated region (3' UTR), respectively. These regions are transcribed with the coding region and thus are ...
  https://en.wikipedia.org/wiki/Messenger_RNA