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*  ENA-78 elisa kit | Porcine Epithelial Neutrophil Activating Peptide 78 ELISA Kit-CAA55355.1
Chemokine Receptors Bind Chemokines Pathway antibodies. Chemokine Receptors Bind Chemokines Pathway Diagram. ... CXCL11 elisa kit >16 publications with ENA-78 and CXCL11. CXCL16 elisa kit >8 publications with ENA-78 and CXCL16. ... Chemokine Signaling Pathway antibodies. Chemokine Signaling Pathway Diagram. Chemokine Signaling Pathway antibodies. Chemokine ... Molecular Function: chemokine activity; CXCR chemokine receptor binding. Biological Process: G-protein coupled receptor protein ...
  https://www.mybiosource.com/prods/ELISA-Kit/Porcine/Epithelial-Neutrophil-Activating-Peptide-78/ENA-78/datasheet.php?products_id=28798
*  CXCR3 - Wikipedia
CXCR3-A binds to the CXC chemokines CXCL9 (MIG), CXCL10 (IP-10), and CXCL11 (I-TAC) whereas CXCR3-B can also bind to CXCL4 in ... Binding of CXCL9, CXCL10, and CXCL11 to CXCR3 is able to elicit increases in intracellular Ca2++ levels and activate ... Binding of chemokines to CXCR3 induces various cellular responses, most notably integrin activation, cytoskeletal changes and ... Chemokine receptor CXCR3 is a Gαi protein-coupled receptor in the CXC chemokine receptor family. Other names for CXCR3 are G ...
  https://en.wikipedia.org/wiki/CXCR3
*  Scientists solve the structure of a membrane protein that is increased in cancer: post #1
has solved the structure of a membrane protein called the atypical chemokine receptor 3 (ACKR3). The study, published online 18 ... ACKR3 is able to bind chemokines CXCL11 and CXCL12. ACKR3 is upregulated in many cancer types, making it a potential drug ... The interactions between chemokines and seven-transmembrane chemokine receptors are known to drive cell migration. Study co- ... has solved the structure of a membrane protein called the atypical chemokine receptor 3 (ACKR3). The study, published online 18 ...
  http://www.protocol-online.org/forums/topic/35688-scientists-solve-the-structure-of-a-membrane-protein-that-is-increased-in-cancer/
*  Pulsed high-dose dexamethasone modulates Th1-/Th2-chemokine imbalance in immune thrombocytopenia | Journal of Translational...
Plasma levels of CCL5 and CXCL11 (Th1-associated) and of CCL11 (Th2-associated) were determined by ELISA. Gene expression of ... Th1-/Th2-associated chemokine and chemokine receptor profiles in ITP patients before and after pulsed HD-DXM was studied. ... Th2-associated chemokines and chemokine receptors may play important roles in the pathogenesis of ITP. Importantly, regulating ... Our aim was to investigate the mechanism of pulsed HD-DXM for management of ITP, specifically regarding the chemokine pathways ...
  https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-016-1064-9
*  Plus it
CXCL12 shares CXCR7 binding with another chemokine, CXCL11, that is also a ligand for CXCR3. CXCR4 triggers preferentially G- ... The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes. J Biol Chem 2005;280:35760-6 ... Chemokine receptor trio: CXCR3, CXCR4, and CXCR7 crosstalk via CXCL11 and CXCL12. Cytokine Growth Factor Rev 2013;24:41-9. ... Forty-seven chemokines have been identified-27 CC and 17 CXC chemokines as well as a single CX3C and two single C chemokines (1 ...
  http://clincancerres.aacrjournals.org/content/21/19/4278
*  Fluidigm | Consumables | Anti-Human CD183/CXCR3 (G025H7)-163Dy-100 Tests
... is a chemokine receptor that binds CXCL9, CXCL10, and CXCL11. ... It is a chemokine receptor that binds CXCL9, CXCL10, and CXCL11 ...
  https://www.fluidigm.com/reagents/proteomics/3163004b-antihuman-cd183-cxcr3--g025h7--163dy--100tests
*  The chemokine receptor CXCR7 interacts with EGFR to promote breast cancer cell proliferation | Molecular Cancer | Full Text
The CXC chemokine receptor-7 (CXCR7) is the latest chemokine receptor implicated in cancer. Although over expressed in breast ... Recent advances have revealed a significant contribution of chemokines and their receptors in tumor growth, survival after ... CXCR7 is a seven-transmembrane receptor that binds chemokines CXCL11/ITAC, CXCL12/SDF-1a, and macrophage migratory inhibitory ... The CXC chemokine receptor-7 (CXCR7) is the latest chemokine receptor implicated in cancer. Although over expressed in breast ...
  https://molecular-cancer.biomedcentral.com/articles/10.1186/1476-4598-13-198
*  124(5)
... and canonically binds 3 structurally related chemokines: CXCL9, CXCL10, and CXCL11. Here we have shown that CXCL10/CXCR3 ... CXCL11 binds CXCR3 with a higher affinity than CXCL10, suggesting that CXCL11 has the potential to restrain inflammatory ... The chemokine-binding GPCR CXCR3 is preferentially expressed on CD4+ T cells, ... Finally, we showed that very low doses of CXCL11 rapidly suppress signs of EAE in C57BL/6 mice lacking functional CXCL11. ...
  https://www.jci.org/124/5
*  CXCL10 // C-X-C motif chemokine 10 | Bioclinica
The CXCR3 receptor also binds the IFN γ inducible chemokines CXCL9 and CXCL11 and the platelet-derived chemokines CXCL4 and ... Antonelli, A., Ferrari, S.M., Giuggioli, D., Ferrannini, E., Ferri, C., and Fallahi, P. (2014). Chemokine (C-X-C motif) ligand ...
  http://bioclinica.com/biomarker-services/biomarker-menu/cxcl10-c-x-c-motif-chemokine-10
*  ACKR3 - Wikipedia
It is now classified as a chemokine receptor able to bind the chemokines CXCL12/SDF-1 and CXCL11. The protein is also a ... Atypical chemokine receptor 3 also known as C-X-C chemokine receptor type 7 (CXCR-7) and G-protein coupled receptor 159 (GPR159 ... "The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes". The Journal of Biological ... "Proteolytic processing of CXCL11 by CD13/aminopeptidase N impairs CXCR3 and CXCR7 binding and signaling and reduces lymphocyte ...
  https://en.wikipedia.org/wiki/ACKR3
*  Protocols and Video Articles Authored by Michael D. Menger (Translated to German)
The CXCL12 pathway is connected with another chemokine, CXCL11, through its second receptor CXCR7. CXCL11 also binds to the ... Interaction of the Chemokines I-TAC (CXCL11) and SDF-1 (CXCL12) in the Regulation of Tumor Angiogenesis of Colorectal Cancer ... PDX-1 binding to its own promoter was not influenced by glucose, whereas USF1 binding to the PDX-1 promoter was reduced. The ... In the present study, we found that (i) CK2 binds to PDX-1, (ii) the binding between CK2 and PDX-1 is regulated by glucose, ( ...
  https://www.jove.com/author/Michael++D._Menger?language=German
*  Protocols and Video Articles Authored by Michael D. Menger (Translated to Hindi)
The CXCL12 pathway is connected with another chemokine, CXCL11, through its second receptor CXCR7. CXCL11 also binds to the ... Interaction of the Chemokines I-TAC (CXCL11) and SDF-1 (CXCL12) in the Regulation of Tumor Angiogenesis of Colorectal Cancer ... In the present study, we found that (i) CK2 binds to PDX-1, (ii) the binding between CK2 and PDX-1 is regulated by glucose, ( ... Leukocyte binding to HDMEC was assessed in an in vitro adhesion assay. Dorsal skinfold chambers in BALB/c mice were used to ...
  https://www.jove.com/author/Michael++D._Menger?language=Hindi
*  Identification of genes differentially expressed in T cells following stimulation with the chemokines CXCL12 and CXCL10 | BMC...
CXCR3 (GPR9; CD183), the receptor for CXCL10 also binds the CXC chemokines CXCL9 and CXCL11 [19]. Recent studies of the CNS ... chemokine receptors that bind only one chemokine specific ligand; (2) chemokine receptors that bind more than one chemokine ... promiscuous chemokine receptors that bind to numerous chemokines [2].. The chemokine receptor CXCR4 binds to the CXC chemokine ... FerritinChemokine ReceptorJurkat CellFerritin Heavy ChainOptimal Migration. Background. CXC and CC chemokines are small soluble ...
  https://bmcimmunol.biomedcentral.com/articles/10.1186/1471-2172-5-17
*  Chemokine Cooperativity Is Caused by Competitive Glycosaminoglycan Binding | The Journal of Immunology
3). Similarly, a GAG-binding-deficient mtCXCL11 (CXCL11 50s or CXCL11K57A,K59A,R62A) was impaired in its ability to cooperate ... Mutant chemokines that do not bind to GAGs do not display chemokine cooperativity. (A) CHO-CCX-CKR cells were treated with ... 2E). These chemokines bind to several GAGs with relatively low affinity compared with other chemokines (e.g., CXCL8, CCL2, and ... A model for chemokine cooperativity. (A) In the absence of cooperative chemokines, CCL19/CCL21 binds to its seven-transmembrane ...
  http://www.jimmunol.org/content/192/8/3908
*  OTTHUMP00000032170 | definition of OTTHUMP00000032170 by Medical dictionary
... which selectively binds CXCL9, CXCL10 and CXCL11; it induces cellular responses involved in leukocyte traffic, most notably ... A gene on chromosome 2q21 that encodes a seven-transmembrane G protein-coupled receptor belonging to the CXC chemokine receptor ...
  https://medical-dictionary.thefreedictionary.com/OTTHUMP00000032170
*  Mouse CXCR3 APC-conjugated Antibody FAB1685A-025: R&D Systems
CXCR3 is a G protein coupled chemokine receptor that binds the alpha chemokines MIG (CXCL9), IP-10 (CXCL10) and I-TAC (CXCL11 ... CD183 antigen; CD183; chemokine (C-X-C motif) receptor 3; chemokine (C-X-C) receptor 3; CKR-L2IP-10 receptor; CMKAR3; C-X-C ... Chemokine receptor CXCR3 promotes growth of glioma.. Authors: Liu C, Luo D, Reynolds BA. Carcinogenesis, 2011;32(2):129-37. ... Chemokine gene expression during fatal murine cerebral malaria and protection due to CXCR3 deficiency.. Authors: Miu J, ...
  https://www.rndsystems.com/products/mouse-cxcr3-apc-conjugated-antibody-220803_fab1685a
*  ACKR3 - Atypical chemokine receptor 3 - Homo sapiens (Human) - ACKR3 gene & protein
Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. Chemokine binding does not activate G-protein-mediated signal ... Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. ... Not involved in cell migration, adhesion or proliferation of normal hematopoietic progenitors but activated by CXCL11 in ... Required for regulation of CXCR4 protein levels in migrating interneurons, thereby adapting their chemokine responsiveness. In ...
  http://www.uniprot.org/uniprot/P25106
*  Atypical Chemokine Receptor 3 (C-X-C Chemokine Receptor Type 7 or Chemokine Orphan Receptor 1 or G Protein Coupled Receptor 159...
C-X-C Chemokine Receptor Type 7 or Chemokine Orphan Receptor 1 or G Protein Coupled Receptor 159 or G Protein Coupled Receptor ... It acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. Chemokine binding does not activate G-protein-mediated signal ... Atypical Chemokine Receptor 3 (C-X-C Chemokine Receptor Type 7 or Chemokine Orphan Receptor 1 or G Protein Coupled Receptor 159 ... It controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven ...
  https://www.researchandmarkets.com/reports/4518521/atypical-chemokine-receptor-3-c-x-c-chemokine
*  A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development | JEM
... also known as CXCL11) strongly displaced 125I SDF-1 binding (Fig. 2 A, top). Similarly, when 125I I-TAC was used as the ... 90 discrete chemokines and chemokine variants to displace the binding of SDF-1 to CEM-NKr and MCF-7 cells was investigated. On ... The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes. J. Biol. Chem. 280:35760- ... Previously I-TAC, as well as two other chemokines, Mig (CXCL9) and IP10 (CXCL10), had been thought to bind only CXCR3 (18, 19 ...
  http://jem.rupress.org/content/203/9/2201
*  Chemokines and Transplant Vasculopathy | Circulation Research
ELR− CXC chemokines include CXCL9, CXCL10, and CXCL11; they bind to their shared receptor CXCR3, which is expressed ... CXC Chemokine/CXC Chemokine Receptor. CXC chemokines are divided based on the presence or absence of the sequence glutamic acid ... Chemokine/Chemokine Receptors. Chemokines are a group of low-molecular-weight (8- to 11-kDa) cytokines that mediate cellular ... CC Chemokine/CC Chemokine Receptor. CC Chemokine Biology During Early Cardiac Allograft Dysfunction. Early cardiac allograft ...
  http://circres.ahajournals.org/content/103/5/454
*  Macrophage-specific metalloelastase (MMP-12) truncates and inactivates ELR+ CXC chemokines and generates CCL2, -7, -8, and -13...
... metalloproteinase processing of CXCL11/I-TAC results in loss of chemoattractant activity and altered glycosaminoglycan binding. ... Chemokine binding and activities mediated by the mouse IL-8 receptor. J Immunol 1995;155:2158-2164. ... The ELR motif in ELR+ CXC chemokines is crucial in cognate receptor binding and activation.5 Therefore, cleavage here is likely ... MMP-12 specifically cleaves human ELR+ CXC chemokines (CXCL1, -2, -3, -5, and -8) at E-LR, the critical receptor-binding motif ...
  http://www.bloodjournal.org/content/112/8/3455?sso-checked=true
*  C-X-C motif chemokine 11 | definition of C-X-C motif chemokine 11 by Medical dictionary
What is C-X-C motif chemokine 11? Meaning of C-X-C motif chemokine 11 medical term. What does C-X-C motif chemokine 11 mean? ... Looking for online definition of C-X-C motif chemokine 11 in the Medical Dictionary? C-X-C motif chemokine 11 explanation free ... CXCL11 induces calcium release in activated T-cells, binds to CXCR3 and may play an important role in CNS diseases involving T- ... CXCL11. (redirected from C-X-C motif chemokine 11) CXCL11. A gene on chromosome 4q21 that encodes a CXC-type chemokine that is ...
  https://medical-dictionary.thefreedictionary.com/C-X-C+motif+chemokine+11
*  US20160244518A1 - Methods for prevention and treatment of inflammation using anti-chemokine antibodies - Google Patents
Identification of chemokines which are over-produced makes it possible to block specific chemokine activity using antibodies to ... It is possible to inhibit inflammatory processes by administration of antibodies to chemokines. ... then evaluating the amount of antibody/chemokine binding, it is possible to evaluate the level of expression for each chemokine ... The 15 amino acid peptides from chemokines CXCL9, CXCL10, CXCL11, CCRL1, CCRL2, CCR5, CCL1, CCL2, CCL3, CCL4, CCL4L1, CCL5, ...
  https://patents.google.com/patent/US20160244518A1/en?oq=US+14%2F843%2C764
*  CXCR3 Gene - GeneCards | CXCR3 Protein | CXCR3 Antibody
C-X-C Motif Chemokine Receptor 3, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - ... and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular ... Chemokine CXC receptors (CXCRs) predominantly recognize CXC chemokines. CXC chemokines are distinguished by having four ... Isoform 3: Mediates the activity of CXCL11. *CXCR3_HUMAN,P49682. GENATLAS Biochemistry: chemokine receptor 3 for the interferon ...
  https://www.genecards.org/cgi-bin/carddisp.pl?gene=CXCR3
*  Transcriptional profiling provides insights into metronomic cyclophosphamide-activated, innate immune-dependent regression of...
Pathways involving tumor-expressed extracellular membrane-bound chemokines CXCL9, CXCL10, and CXCL11 were identified and show ... included several chemokines and chemokine receptors (CXCL9, CXCL10, CXCL11, CCL5, CCL26, CCR1), interleukins and interleukin ... NK cell-expressed chemokine receptor Cxcr3 (the known interacting receptor for chemokines CXCL9, CXCL10, and CXCL11), MHC class ... which binds tumor-cell specific membrane-bound activation ligands CXCL9, CXCL10, and CXCL11 [106], all of which were also ...
  https://bmccancer.biomedcentral.com/articles/10.1186/s12885-015-1358-y