*  Abstract 2841: Beta-Blocker Therapy Abolishes Postsystolic Shortening in Patients with Nonischemic Dilated Cardiomyopathy |...
Postsystolic shortening (PSS), a positive myocardial velocity after aortic valve closure as assessed by tissue Doppler imaging (TDI), is a common finding in patients with myocardial disease. Beta-blocker therapy is shown to improve both global and regional myocardial function. The aim of the present study was to examine whether beta-blocker therapy might reduce incidence and magnitude of PSS in patients with nonischemic dilated cardiomyopathy. Before and a few months after beta-blocker (carvedilol) therapy, 19 patients (7 men and 12 women, age 59±13 years) underwent conventional echo-assessment and TDI. From the apical two, four, and long-axis views, we constructed time velocity curves at the 12 basal and mid-myocardial segments of the left ventricular (LV) walls. PSS was defined if the positive myocardial velocity after aortic valve closure was greater than the ejection peak (Figure⇓). The number of PSS was counted before and after ...
  http://circ.ahajournals.org/content/118/Suppl_18/S_785.4
*  Abstract 16243: Beta-Blocker Therapy Reduce Threshold for Exercise Induced Ventricular Arrhythmias in Patients with CPVT |...
Introduction: Catecolaminergic polymorphic ventricular tachycardia (CPVT) is an inherited cardiac disease which predisposes to exercise-induced life-threatening arrhythmias. The current therapeutic recommendations are beta-blocker therapy and ICD implantation. We aimed to determine the effect of beta-blocker treatment on exercise-induced arrhythmias in CPVT patients.. Methods: A total of 38 CPVT patients were followed for 24 (8-288) months. Of these, 8 were index patients and 30 were mutation positive family members diagnosed by cascade genetic screening. Clinical evaluation including exercise test was performed at inclusion and repeated 3 months after initiation of beta-blocker therapy in maximum tolerable doses. Heart rate and workload at occurrence of ventricular premature beats (VPB), couplets and non-sustained VT (nsVT) were recorded.. Results: Exercise-induced arrhythmias were observed in 28 (79 %) patients before treatment. Resting and maximum heart ...
  http://circ.ahajournals.org/content/122/Suppl_21/A16243
*  Investigating the adverse respiratory effects of beta-blocker treatment: six years of prospective longitudinal data in a cohort...
Cochrane, B., Quinn, S., Walters, H. and Young, I. (2012), Investigating the adverse respiratory effects of beta-blocker treatment: six years of prospective longitudinal data in a cohort with cardiac disease. Internal Medicine Journal, 42: 786-793. doi: 10.1111/j.1445-5994.2011.02563.x ...
  http://onlinelibrary.wiley.com/doi/10.1111/j.1445-5994.2011.02563.x/references
*  Esmolol Infusion During Laminectomy: Effect on Quality of Recovery - Full Text View - ClinicalTrials.gov
A common practice used to control autonomic responses during surgery is to administer beta-blockers intraoperatively. This practice has been shown to effectively blunt autonomic responses to intraoperative events. Several studies have shown that administration of beta-blockers can decrease intraoperative anesthetic requirements. Additionally, it has been demonstrated in several studies that intraoperative beta-blocker administration may actually decrease postoperative pain scores and opioid requirements, although these results are not entirely consistent. The mechanism by which the decrease in postoperative pain and narcotic requirements occurs is unclear. It has been postulated that esmolol may itself possess some analgesic-like properties, as was suggested by studies performed in rodent models. It has also been postulated that perioperative beta-blockade may attenuate the neuroendocrine stress response to ...
  https://clinicaltrials.gov/ct2/show/NCT01179113
*  Gestational Outcomes of Beta Blocker Therapy as a Treatment of Palpitations | OMICS International
According to the reports from Ministry of Health in each country, the average life spans were expanded over the past century. This trend is expected to be extended furt..
  https://www.omicsonline.org/open-access/gestational-outcomes-of-beta-blocker-therapy-as-a-treatment-of-palpitations-2155-9880-1000537.php?aid=92028
*  Ivabradine - DrugBank
Ivabradine is a novel heart rate lowering medicine for the symptomatic management of stable angina pectoralis and symptomatic chronic heart failure. Ivabradine, brand name Corlanor, was approved by the FDA in April 2015 for the treatment of chronic heart failure in patients with an ejection fraction of ≤35%, in sinus rhythm with resting heart rate ≥70 beats per minute, who are not on beta-blockers due to contraindications or already receiving maximum beta-blocker dose. Ivabradine acts by selectively inhibiting the
  https://www.drugbank.ca/drugs/DB09083
*  Abstract 11877: Beta-blocker Dose Stratifies Both Mortality Risk and Circulating Procollagen Levels In African-Americans With...
Introduction: While African Americans (AAs) have the highest prevalence of heart failure (HF) and HF mortality, insufficient data exists regarding the impact of HF medication on mortality in AAs. This study aimed to identify medication use practices associated with survival in a predominantly AA HF population.. Methods: HF patients were prospectively recruited from, and followed within, the University of Illinois Health System from 11/2001 to 11/2015, when vital status was determined. Data were extracted from electronic health records and Social Security Death Index. Beta-blocker (BB), ACE-I, and ARB doses were categorized as high, medium, or low based on published HF trials. Associations between dose and all-cause mortality were assessed using a Cox proportional hazard model, adjusting for enrollment age, sex, race, ischemic or non-ischemic etiology, NYHA functional class, and concomitant HF medication use. Using linear regression (adjusted for the same covariates), doses were also compared ...
  http://circ.ahajournals.org/content/134/Suppl_1/A11877
*  BB-meta-HF: Efficacy of beta-blockers in heart failure patients with atrial fibr
A total of 18,254 participants were assessed, of which 13,946 (76.4%) were in sinus rhythm and 3,066 (16.8%) in AF. Crude death rates over a mean follow-up of 1.5 years (SD 1.1) were 16.0% in sinus rhythm and 20.7% in AF. Beta-blocker therapy in patients with sinus rhythm led to a significant reduction in all-cause mortality (HR 0.73, 0.67-0.80; p,0.001) and CV-hospitalisation (HR 0.78, 0.73-0.83; p,0.001), as well as CV-death, HF-hospitalisation, the composite of all-cause mortality/CV-hospitalisation and the composite of CV-death/HF-hospitalisation. In contrast, there was no apparent effect from beta-blockers on any outcome in patients with AF, including mortality (HR 0.97, 0.83-1.14; p=0.73) and CV-hospitalisation (HR 0.91, 0.79-1.04; p=0.15). All outcomes demonstrated significant interaction p-values for beta-blocker efficacy according to baseline rhythm. The lack of efficacy for mortality was seen across all AF sub-groups. AF patients ...
  https://www.escardio.org/Congresses-%26-Events/ESC-Congress/Congress-resources/Session-Reports/Reports-2014/BB-meta-HF-Efficacy-of-beta-blockers-in-heart-failure-patients-with-atrial-fibr
*  Preventive Cardiology: Beta-blockers | Kendall Regional Medical Center | Miami, FL
Learn more about Preventive Cardiology: Beta-blockers at Kendall Regional Medical Center Current UsesHow Beta-Blockers WorkWhat You Should Knowrevision ...
  https://kendallmed.com/hl/?/29883/beta-blockers&com.dotmarketing.htmlpage.language=1
*  Beta-blockers | Reston Hospital Center
Learn more about Beta-blockers at Reston Hospital Center Coenzyme Q 10 (CoQ 10 ) -Supplementation....
  http://restonhospital.com/hl/?/21397/Atenolol
*  Beta-blockers | Doctors Hospital
Learn more about Beta-blockers at Doctors Hospital of Augusta Coenzyme Q 10 (CoQ 10 ) -Supplementation...
  http://doctors-hospital.net/hl/?/21397/Timolol-Maleate&com.dotmarketing.htmlpage.language=1
*  Beta-blockers | Doctors Hospital
Learn more about Beta-blockers at Doctors Hospital of Augusta Coenzyme Q 10 (CoQ 10 ) -Supplementation...
  https://doctors-hospital.net/hl/?/21397/Carteolol&com.dotmarketing.htmlpage.language=1
*  Beta-blockers | Doctors Hospital
Learn more about Beta-blockers at Doctors Hospital of Augusta Coenzyme Q 10 (CoQ 10 ) -Supplementation...
  https://doctors-hospital.net/hl/?/21397/Esmolol-Hydrochloride&com.dotmarketing.htmlpage.language=1
*  Beta-blockers | Memorial Hospital
Learn more about Beta-blockers at Memorial Hospital Coenzyme Q 10 (CoQ 10 ) -Supplementation...
  https://memorialhospitaljax.com/hl/?/21397/Betachron-E-R&com.dotmarketing.htmlpage.language=1
*  Beta-blockers | Memorial Hospital
Learn more about Beta-blockers at Memorial Hospital Coenzyme Q 10 (CoQ 10 ) -Supplementation...
  https://memorialhospitaljax.com/hl/?/21397/Timolol-Maleate&com.dotmarketing.htmlpage.language=1
*  Beta-blockers | Oak Hill Hospital | Brooksville, FL
Learn more about Beta-blockers at Oak Hill Hospital Coenzyme Q 10 (CoQ 10 ) -Supplementation...
  https://oakhillhospital.com/hl/?/21397/Cartrol&com.dotmarketing.htmlpage.language=1
*  Beta-blockers | Portsmouth Regional Hospital
Learn more about Beta-blockers at Portsmouth Regional Hospital Coenzyme Q 10 (CoQ 10 ) -Supplementation...
  https://portsmouthhospital.com/hl/?/21397/Beta-Blockers&com.dotmarketing.htmlpage.language=1
*  Beta-blockers | Memorial Hospital
Learn more about Beta-blockers at Memorial Hospital Coenzyme Q 10 (CoQ 10 ) -Supplementation...
  http://memorialhospitaljax.com/hl/?/21397/Trandate&com.dotmarketing.htmlpage.language=1
*  Beta-blockers | Largo Medical Center | Largo, FL
Learn more about Beta-blockers at Largo Medical Center Coenzyme Q 10 (CoQ 10 ) -Supplementation...
  https://largomedical.com/hl/?/21397/Atenolol
*  Beta-blockers | Regional Medical Center Bayonet Point | Hudson, FL
Learn more about Beta-blockers at Regional Medical Center Bayonet Point Coenzyme Q 10 (CoQ 10 ) -Supplementation...
  https://rmchealth.com/hl/?/21397/Lopressor&com.dotmarketing.htmlpage.language=1
*  Beta-blockers | Regional Medical Center Bayonet Point | Hudson, FL
Learn more about Beta-blockers at Regional Medical Center Bayonet Point Coenzyme Q 10 (CoQ 10 ) -Supplementation...
  https://rmchealth.com/hl/?/21397/Sectral&com.dotmarketing.htmlpage.language=1
*  Beta-blockers | Wesley Medical Center
Learn more about Beta-blockers at Wesley Medical Center Coenzyme Q 10 (CoQ 10 ) -Supplementation.....
  https://wesleymc.com/hl/?/2010814684/Beta-blockers
*  Beta-blockers | Orange Park Medical Center
Learn more about Beta-blockers at Orange Park Medical Center Coenzyme Q 10 (CoQ 10 ) -Supplementation...
  http://orangeparkmedical.com/hl/?/2010814684/Beta-blockers&com.dotmarketing.htmlpage.language=1