*  THE HOMOGENEITY OF RAT-LIVER MICROSOMAL CYTOCHROME-P-448 ACTIVITY AND ITS ROLE IN THE ACTIVATION OF BENZO[A]PYRENE TO MUTAGENS ...
THE HOMOGENEITY OF RAT-LIVER MICROSOMAL CYTOCHROME-P-448 ACTIVITY AND ITS ROLE IN THE ACTIVATION OF BENZO[A]PYRENE TO MUTAGENS ... THE HOMOGENEITY OF RAT-LIVER MICROSOMAL CYTOCHROME-P-448 ACTIVITY AND ITS ROLE IN THE ACTIVATION OF BENZO[A]PYRENE TO MUTAGENS ...
  http://epubs.surrey.ac.uk/823360/
*  ZFIN Publication: Knecht et al., 2017
Benzo[a]pyrene (B[a]P) is a well-known genotoxic polycylic aromatic compound whose toxicity is dependent on signaling via the ... Exposure to benzo[a]pyrene during development resulted in transgenerational inheritance of neurobehavioral and physiological ... Aryl hydrocarbon receptor, Benzo[a]pyrene, Developmental toxicity, Neurobehavioral, Physiological deficits, Transgenerational, ... Animals; Animals, Genetically Modified; Behavior, Animal/drug effects*; Benzo(a)pyrene/toxicity*; DNA Methylation/drug effects ...
  http://zfin.org/ZDB-PUB-170607-4
*  Sarcoma-Producing Cell Lines Derived from Clones Transformed in vitro by Benzo[a]pyrene | Science
Cells derived from mixed Syrian hamster embryo cultures were treated with pyrene (control) or with benzo[a]pyrene. Transformed ... Sarcoma-Producing Cell Lines Derived from Clones Transformed in vitro by Benzo[a]pyrene ... Sarcoma-Producing Cell Lines Derived from Clones Transformed in vitro by Benzo[a]pyrene ... Sarcoma-Producing Cell Lines Derived from Clones Transformed in vitro by Benzo[a]pyrene ...
  http://science.sciencemag.org/content/165/3896/917
*  "Carcinogenicity of benzo-ring derivatives of benzo(a)pyrene on mouse s" by W Levin, A W. Wood et al.
Carcinogenicity of benzo-ring derivatives of benzo(a)pyrene on mouse skin. ... "Carcinogenicity of benzo-ring derivatives of benzo(a)pyrene on mouse skin." (1977). Subject Strain Bibliography 1977. 715. ...
  https://mouseion.jax.org/ssbb1977/715/
*  benzo[a]pyrene | C20H12 - PubChem
... pyrene , C20H12 , CID 2336 - structure, chemical names, physical and chemical properties, classification, patents, literature, ...
  https://pubchem.ncbi.nlm.nih.gov/compound/benzo_a_pyrene
*  Benzo[a]pyrene (BaP) CASRN 50-32-8 | IRIS | US EPA, ORD
Benzo[a]pyrene (BaP). CASRN 50-32-8. *Toxicological Review (PDF) (234 pp, 4.67 M) ... Under EPA's Guidelines for Carcinogen Risk Assessment (U.S. EPA, 2005a), benzo[a]pyrene is "carcinogenic to humans" based on ... Sep 2016: IRIS Toxicological Review of Benzo[a]pyrene (Interagency Science Discussion Draft) (Report) ... Jun 2011: IRIS Toxicological Review of Benzo[a]pyrene (Interagency Science Consultation Draft) (Report) ...
  https://cfpub.epa.gov/ncea/iris2/chemicalLanding.cfm?substance_nmbr=136
*  "Interaction of benzo(a)pyrene and its dihydrodiol-epoxide derivative w" by J M. Backer and I B. Weinstein
Interaction of benzo(a)pyrene and its dihydrodiol-epoxide derivative with nuclear and mitochondrial dna in c3h10t1/2 cell ... Backer, J M. and Weinstein, I B., "Interaction of benzo(a)pyrene and its dihydrodiol-epoxide derivative with nuclear and ...
  https://mouseion.jax.org/ssbb1982/181/
*  Tentative Identification of Benzo[a]pyrene Metabolite-Nucleoside Complexes Produced in Vitro by Mouse Liver Microsomes |...
... pyrene phenols. The 7,8-oxide and the 9,10-oxide contribute to peaks E, F, G, and H. Benzo[a] pyrene thus may be metabolized to ... pyrene. Peaks A and C are unidentified. Peaks B, D, F, and I include products of benzo[a]pyrene quinones that are further ... Tentative Identification of Benzo[a]pyrene Metabolite-Nucleoside Complexes Produced in Vitro by Mouse Liver Microsomes. OLAVI ... Tentative Identification of Benzo[a]pyrene Metabolite-Nucleoside Complexes Produced in Vitro by Mouse Liver Microsomes. OLAVI ...
  http://molpharm.aspetjournals.org/content/14/2/306
*  Transpacific transport of benzo[a]pyrene emitted from Asia
Zhang, Y., Tao, S., Ma, J., & Simonich, S. (2011). Transpacific transport of benzo[a]pyrene emitted from asia. Atmospheric ... Transpacific transport of benzo[a]pyrene emitted from Asia Public Deposited Citeable URL:. http://ir.library.oregonstate.edu/ ... SimonichSChemistryTranspacificTransportBenzo_a_pyrene.pdf. 2017-07-11. Public. Press to Select an action * Download ... three dimensional atmospheric transport and chemistry model was applied to simulate transpacific transport of Benzo[a]pyrene ( ...
  https://ir.library.oregonstate.edu/concern/defaults/2r36tz23z
*  Aryl hydrocarbon (benzo[a]pyrene) hydroxylases in liver from rats of different age, sex and nutritional status. Distinction of...
... benzo[a]pyrene) hydroxylases in liver from rats of different age, sex and nutritional status. Distinction of two types by 7,8- ... Aryl hydrocarbon (benzo[a]pyrene) hydroxylases in liver from rats of different age, sex and nutritional status. Distinction of ... article{Wiebel1975ArylH, title={Aryl hydrocarbon (benzo[a]pyrene) hydroxylases in liver from rats of different age, sex and ...
  https://www.semanticscholar.org/paper/Aryl-hydrocarbon-benzo-a-pyrene-hydroxylases-in-li-Wiebel-Gelboin/87ca945175919431b5583b6dfe254fe45cf8e02b
*  "Leukemia in mice fed benzo(a)pyrene, a clinical, pathologic and hemato" by R H. Rigdon, M C. Benge et al.
Rigdon, R H.; Benge, M C.; Kirchoff, H; Mack, J; and Neal, J, "Leukemia in mice fed benzo(a)pyrene, a clinical, pathologic and ... Leukemia in mice fed benzo(a)pyrene, a clinical, pathologic and hematologic study. ...
  https://mouseion.jax.org/ssbb1969/1799/
*  Enzyme immunoassay of benzo[a]pyrene conjugated to DNA, RNA and microsomal proteins using a monoclonal antibody. - Semantic...
... pyrene metabolites bound to DNA, RNA and proteins. The lower detection limit for the assay was 1 pmol for benzo[a]pyrene bound ... The monoclonal antibody, raised through in vitro immunization reacted with benzo[a] ... pyrene covalently conjugated to macromolecules has been developed. ... An enzyme immunoassay for the detection of benzo[a] ... Enzyme immunoassay of benzo[a]pyrene conjugated to DNA, RNA and ...
  https://www.semanticscholar.org/paper/Enzyme-immunoassay-of-benzo-a-pyrene-conjugated-to-Wallin-Borrebaeck/9877edcc0bbb0a62e3aa44ba46aab97c2e32a42f
*  NIOSHTIC-2 Publications Search - 00187006 - Binding of benzo(a)pyrene to hepatic cytosolic protein enhances its microsomal...
... pyrene (50328) (BaP) to a protein in rat liver cytosol facilitates its oxidation by microsomal enzymes. Cytosols were prepared ... Evidence was presented to indicate that the binding of benzo(a) ... Binding of benzo(a)pyrene to hepatic cytosolic protein enhances ... Evidence was presented to indicate that the binding of benzo(a)pyrene (50328) (BaP) to a protein in rat liver cytosol ... NIOSH-Publication; NIOSH-Grant; Dermatitis; Liver-enzymes; Enzyme-activity; Metabolic-study; Pyrenes; Lipids; Carcinogens; ...
  https://www.cdc.gov/niosh/nioshtic-2/00187006.html
*  Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments...
... including benzo[a]pyrene (BaP), are metabolically activated by cytochrome P450s (CYPs). In order to evaluate the role of ... including benzo[a]pyrene (BaP), are metabolically activated by cytochrome P450s (CYPs). In order to evaluate the role of ... pyrene by liquid chromatography-tandem mass spectrometry analysis. Hepatic microsomes isolated from BaP-treated and untreated ...
  http://oxfordindex.oup.com/view/10.1093/carcin/bgn002
*  Benzopyrene - Wikipedia
Two isomeric species of benzopyrene are benzo[a]pyrene and the less common benzo[e]pyrene. They belong to the chemical class of ... Benzo[a]pyrene Benzo[e]pyrene W. D. Betts "Tar and Pitch" in Kirk‑Othmer Encyclopedia of Chemical Technology, 1997, John Wiley ... benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide from benzo[a]pyrene) which intercalate into DNA, interfering with transcription. ... Denissenko, M. F.; Pao, A.; Tang, M.-s.; Pfeifer, G. P. (1996). "Preferential Formation of Benzo[a]pyrene Adducts at Lung ...
  https://en.wikipedia.org/wiki/Benzopyrene
*  Benzo(e)pyrene - Wikipedia
Benzopyrene Benzo[a]pyrene Benzene Pyrene, a four-ring analogue Hoover, Rachel (February 21, 2014). "Need to Track Organic Nano ... Benzo[e]pyrene is a polycyclic aromatic hydrocarbon with the chemical formula C20H12. It is listed as a Group 3 carcinogen by ... including Benzo[e]pyrene, in the universe. According to scientists, more than 20% of the carbon in the universe may be ...
  https://en.wikipedia.org/wiki/Benzo(e)pyrene
*  Benzo(a)pyrene - Wikipedia
Benzopyrene Benzo[e]pyrene Pyrene, a four-ring analogue Toxification "benzo[a]pyrene". pubchem.ncbi.nlm.nih.gov. Assessment of ... Benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide is the carcinogenic product of three enzymatic reactions: Benzo[a]pyrene is first ... pyrene-7,8-epoxide. This product is metabolized by epoxide hydrolase, opening up the epoxide ring to yield (-)benzo[a]pyrene-7, ... Benzo[a]pyrene (BaP) is a polycyclic aromatic hydrocarbon found in coal tar with the formula C20H12. The compound is one of the ...
  https://en.wikipedia.org/wiki/Benzo(a)pyrene
*  Benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide - Wikipedia
Benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide is a metabolite of benzo[a]pyrene formed by the introduction of vicinal hydroxyl ... Benzo[a]pyrene is a derivative in which a fifth benzene ring has been fused to the pyrene system, and is a component of tobacco ... pyrene, but the syn isomers are also produced. (+)-Benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide has been shown to bind to an N2 ... pyrene-7,8-epoxide. The enzyme epoxide hydrolase, then hydrates the epoxide ring to yield the vicinal diol (−)-benzo[a]pyrene-7 ...
  https://en.wikipedia.org/wiki/(+)-Benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide
*  Benzopyrene dictionary definition | benzopyrene defined
and known to be a cause of cancer in animalssometimes called benz·py′rene Origin of benzopyrene benzo- + pyrene... ... benzopyrene definition: an aromatic hydrocarbon, CH, found in coal tar, cigarette smoke, etc. ... benzopyrene. ben·zo·py·rene. an aromatic hydrocarbon, CH, found in coal tar, cigarette smoke, etc. and known to be a cause of ... plural benzopyrenes) (Properly: benzo[a]pyrene). *(organic chemistry) A polycyclic aromatic hydrocarbon (having five fused ...
  http://www.yourdictionary.com/benzopyrene
*  Benzo[a]pyrene, 4,5-dihydro
The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
  https://webbook.nist.gov/cgi/inchi/InChI%3D1S/C20H14/c1-2-7-17-15
*  Benzo(a)pyrene - Toxicity | Technology Trends
Benzo(a)pyrene - Toxicity. Toxicity. A vast number of studies over the previous three decades have documented links between ... benzopyrene toxicity results from the bioactivation of benzopyrene to the ultimate toxic compound, benzopyrene -7,8-dihydrodiol ... Benzopyrene, found in tobacco smoke (including cigarette smoke), was shown to cause genetic damage in lung cells that was ... Thus in most cases small amounts of benzopyrene are metabolized by gut enzymes prior to being passed on to the blood. The lungs ...
  http://www.primidi.com/benzoapyrene/toxicity
*  Benzo[a]pyrene-7,8-dione | C20H10O2 - PubChem
... pyrene-7,8-dione , C20H10O2 , CID 105020 - structure, chemical names, physical and chemical properties, classification, patents ...
  https://pubchem.ncbi.nlm.nih.gov/compound/Benzo_a_pyrene-7_8-dione
*  Relief on the Way for Benzo[a]pyrene Cleanups? - Lexology
Land developers and remediators in Pennsylvania and New Jersey may soon have an easier time addressing soils containing benzo[a ... Benzo[a]pyrene is a polynuclear aromatic hydrocarbon (PAH) and is found as the result of the combustion of organic matter such ... Benzo[a]pyrene is often the highest-risk contaminant at sites impacted by PAHs and historic fill materials such as ash, and ... While the Final Assessment concludes that benzo[a]pyrene is still a potent carcinogen, the revised parameters show that the ...
  https://www.lexology.com/library/detail.aspx?g=672ea3e0-ce17-4559-be82-ef452d1bba4a