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*  Autismo e doenças invasivas de desenvolvimento
... with some visual stimuli and high tolerance of pain, also contribute to behavioral disorders in autistic patients. Mood and ... Abnormal responses to sensory stimuli, such as loud sounds, tactile hypersensitivity, fascination ... functional behavioral analysis and in behavioral change techniques. In addition to social and cognitive deficits, behavioral ... The treatment of autistic patients requires a multidisciplinary approach. Basic treatment consists of behavioral changes, ...
  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572004000300011&lng=pt&tlng=en
*  Matrix Metalloproteinases and Minocycline: Therapeutic Avenues for Fragile X Syndrome
... behavioral neuroscience, cognitive neuroscience, biological psychology, and biological psychiatry. ... Behavioral problems include hyperactivity and hypersensitivity to sensory stimuli, anxiety and mood disorders, disrupted sleep ... patients present with a wide spectrum of behavioral, physical, and neurological symptoms [4-6]. ... Of the FXS patients followed throughout the course of the study, most displayed improvements in several areas, including ...
  https://www.hindawi.com/journals/np/2012/124548/
*  Foundations of Skills Training by Chris Skidmore on Prezi
behavioral urges. , and emotion-linked actions or habits.. Heightened emotional sensitivity. (hypersensitivity to emotional ... RCT; Chronically suicidal BPD patients (N=47) randomly assigned to 1 year of DBT or to treatment as usual (TAU) in community. ... extreme reactions to emotional stimuli, disrupted cognitive processing and self soothing). BPD was re-conceptualized as a ... Cognitive-Behavioral Therapy Didactics Series, October 2016. When was the last time you felt that way?. References. Linehan, M ...
  https://prezi.com/kadbx61vr3qu/foundations-of-skills-training/
*  Oral Care Tips for Aging Teeth
Tai Chi as Exercise Option for Patients With Heart Disease. Cognitive Behavioral Therapy to Treat Menopausal Symptoms. ... Dentin Hypersensitivity. Dentin hypersensitivity is an oral condition characterized by sharp pain in the affected dental area ... If an elder person is not comfortable with his/her dentist, then choose a dentist who is trained to treat elderly patients. ...
  http://www.medindia.net/patients/lifestyleandwellness/oral-care-tips-for-aging-teeth.htm
*  Plus it
2009) Trait impulsivity predicts escalation of sucrose seeking and hypersensitivity to sucrose-associated stimuli. Behav ... Behavioral training in the five-choice serial reaction time task.. Detailed description of the behavioral apparatus and ... in patients suffering from ADHD. In this respect, recent studies showed that motor impulsivity in rats may be a risk factor for ... but also escalation of sucrose seeking and hypersensitivity to sucrose-associated stimuli (Diergaarde et al., 2009). It is ...
  http://www.jneurosci.org/content/31/4/1284
*  Sleep disturbances are associated with specific sensory sensitivities in children with autism | Springer for Research &...
ERP evidence of enhanced excitatory and reduced inhibitory processes of auditory stimuli during sleep in patients with primary ... Sensory hypersensitivity as a contributing factor in the relation between sleep and behavioral disorders in normal ... 2). Note that children can be hypersensitive to some stimuli and hyposensitive to other stimuli even within the same sensory ... both vestibular hypersensitivity and hypersensitivity towards touch scores single-handedly explained a considerable amount of ...
  https://rd.springer.com/article/10.1186/s13229-018-0206-8
*  Fragile X syndrome - Wikipedia
Refractive errors in patients with FXS are also common. Individuals with FXS are at a higher risk of developing seizures, with ... Behavioral therapy can be used to decrease the child's sensitivity in some cases. Perseveration is a common communicative and ... Children with fragile X have very short attention spans, are hyperactive, and show hypersensitivity to visual, auditory, ... tactile, and olfactory stimuli. These children have difficulty in large crowds due to the loud noises and this can lead to ...
  https://en.wikipedia.org/wiki/Fragile_X_syndrome
*  Plus it
When a neuron responsive to the above stimuli was identified, the colon was distended for 10 sec at 80 mmHg to test whether the ... Behavioral/Systems/Cognitive. *. Influence of Reward on Corticospinal Excitability during Movement Preparation ... 1995) Altered rectal perception is a biological marker of patients with irritable bowel syndrome. Gastroenterology 109:40-52. ... The loss of gonadal hormones decreases sensitivity, and estrogen replacement leads to recovery and some hypersensitivity. The ...
  http://www.jneurosci.org/content/23/9/3908
*  We're Making Progress! - Migraine Research Foundation
Demonstrated the promise of a brief behavioral sleep intervention for migraine patients, suggesting that directly treating co- ... Found that a high sensitivity to external stimuli predicts the effectiveness of amitriptyline in preventing migraine, opening ... Discovered ground-breaking information about BDNF, a protein that could cause pain hypersensitivity in migraine. ... Found that brief behavioral interventions, especially cognitive behavioral therapy, may reduce headache frequency and anxiety ...
  https://migraineresearchfoundation.org/migraine-research-progress/
*  Interoception - Wikipedia
... showing positive outcomes for some patients. Nociception refers to the receiving and processing of pain inducing stimuli by the ... These sensory and affective characteristics of thermoregulation may motivate certain behavioral responses depending on the ... paradigms have been used to study how innocuous signals might lead to abnormal states of gastrointestinal hypersensitivity and ... patients with MDD are less accurate at counting heartbeat than are patients with panic or anxiety disorders. However, patients ...
  https://en.wikipedia.org/wiki/Interoception
*  Mind-Body Techniques for Pain Management - The Rheumatologist
Patients who catastrophize have more pain,' added Dr. Chiaramonte. 'That is so important for us to know, because we can teach ... This central sensitization amplifies neural signaling and elicits pain hypersensitivity. "The CNS is distorting how much pain ... It can include, for example, cognitive behavioral therapy, medications and acupuncture. A key concept in integrative pain ... distort and amplify pain such that the symptoms no longer directly reflect the peripheral noxious stimuli. ...
  http://www.the-rheumatologist.org/article/mind-body-techniques-pain-management/
*  Depersonalization disorder - Wikipedia
... due to threat hypersensitivity and an external locus of control. One cognitive behavioral conceptualization is that ... Patients demonstrate abnormal cortisol levels and basal activity. Studies found that patients with DPD could be distinguished ... In a test of skin conductance responses to unpleasant stimuli, the subjects showed a selective inhibitory mechanism on ... Patients with drug-induced depersonalization do not appear to be a clinically separate group from those with a non-drug ...
  https://en.wikipedia.org/wiki/Depersonalization_disorder
*  Different cochleovestibular manifestations and outcomes in patients diagnosed with dengue | Brazilian Journal of...
9 and further induces compensatory changes in central auditory pathways that increase behavioral responses to sound stimuli.10 ... Moreover, 25-40% of patient's also present hypersensitivity to sounds (hyperacusis). Both symptoms could reflect synaptic ... almost all patients with vertigo also had hearing loss (28/30), and patients without hearing loss did not have vertigo (19/21). ... Three patients started tinnitus during dengue and have partial or total improvement: MNFM (Case 2) and GPNN (Case 3), who also ...
  http://rborl.org.br/en-different-cochleovestibular-manifestations-outcomes-in-avance-S1808869417301386
*  Sensory Integration Therapy and Auditory Integration Therapy
Comparison of behavioral intervention and sensory-integration therapy in the treatment of challenging behavior. J Autism Dev ... Sensory integration refers to the process by which the brain organizes and interprets external stimuli such as touch, movement ... Due to the individual nature of sensory integration therapy and the large variation in individual therapists and patients, ... is an intervention developed to correct or improve auditory hypersensitivity, distortions, and delays in the signals that ...
  https://www.wellmark.com/Provider/MedPoliciesAndAuthorizations/MedicalPolicies/policies/Sensory_Integration_Therapy.aspx
*  EMA401 - Wikipedia
This causes behavioral hypersensitivity of TRPV1 to its stimuli. Increased AT2R activity causes hyperalgesia. AT2R antagonist ... patients taking EMA401 did not show any difference in vital signs or 12-lead ECG assessments compared to the patients taking ... Relief of hindpaw hypersensitivity was dose dependent. EMA400 had the highest antineuropathic potency, 60-fold more potent than ... It was initially established as a potential drug option for patients suffering pain caused by postherpetic neuralgia. It may ...
  https://en.wikipedia.org/wiki/EMA401
*  How Your Brain and Emotions Control Your Gut and Cause Pain
... cognitive behavioral therapy, breathing techniques and other behaviors relieve GI pain and problems. ... Director of Behavioral Medicine. Digestive Health Program. We all understand what it means to have a "gut feeling," or to feel ... For many patients, living with unpredictable GI symptoms can be highly stressful on its own. Having to find a bathroom at a ... "visceral hypersensitivity," meaning that the nerves of the gut are overly sensitive and firing in response to normal digestion ...
  https://www.loyolamedicine.org/blog/how-your-brain-and-emotions-control-your-gut
*  Examining the Reversibility of Long-Term Behavioral Disruptions in Progeny of Maternal SSRI Exposure | eNeuro
SSRI treatment ameliorated the hypersensitivity to sensory stimuli but further exacerbated the response to social stimuli. ... of ASD patients exhibit elevated 5-HT levels in whole-blood platelets (Benza and Chugani, 2015), changes to 5-HT can either ... Adult behavioral testing for all cohorts began at P60. Adult behavioral testing of the Celf6-Extended cohort included a battery ... In: Handbook of behavioral neuroscience, handbook of the behavioral neurobiology of serotonin, Chap 3.1 ( Jacobs BL, Muller CP ...
  http://www.eneuro.org/content/5/4/ENEURO.0120-18.2018
*  Frontiers | Amantadine in the Treatment of Pathological Gambling: A Case Report | Psychiatry
... the devastating consequences of this behavioral disturbance often entail severe damage to the lives of patients and their ... 2012) suggested that the dopaminergic response to reward-predicting stimuli and the link between addiction severity and DA ... hypersensitivity to reward and sustained activation toward uncertainty (Linnet et al., 2012). Furthermore, Joutsa et al. ( ... In cocaine-dependent patients with severe withdrawal symptoms, Kampman et al. (2000) found that amantadine was effective. Two ...
  https://www.frontiersin.org/articles/10.3389/fpsyt.2012.00102/full
*  Gag reflex
Patients had to write down the length of the time the base plate was worn each day so that one day's time could be compared ... Chronic diseases of gastrointestinal tract which increase its irritability so that normally sub-threshold stimuli excite the ... 6. 5. Social causes of gagging includes : - Heavy smoking which causes gagging result of hypersensitivity. - Chronic catarrah ... treated cases of hopeless gagger in whom they rapidly eliminated the hyperactive reflex by a method they formed as behavioral ...
  https://www.slideshare.net/indiandentalacademy/gag-reflex
*  Calcium Channel α2δ1 Subunit Mediates Spinal Hyperexcitability in Pain Modulation
The enhanced and prolonged responses to stimuli in dorsal horn neurons mirrored the extent of the reduced behavioral thresholds ... δ1 is highly likely the common factor associated with similar behavioral hypersensitivity in both models. Although the abnormal ... with increased duration of aftersensation to low levels of mechanical stimuli has been reported in neuropathic pain patients. ... Behavioral assays. After 1 h acclimation, mouse behavioral response to mechanical stimulation was tested as described ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC1635965/?lang=en-ca
*  Biology of bipolar disorder - Wikipedia
Depressed patients are quicker to react to negatively valenced stimuli, while manic patients are quicker to react to positively ... Using this behavioral pattern in "reverse translational" studies, this behavioral abnormality has been associated with the ... Hypersensitivity of reward systems is consistent across mood states in bipolar, and is evident in the prodrome. Increases in ... Serotonin may play a role in mania by increasing the salience of stimuli related to reward. One more line of evidence that ...
  https://en.wikipedia.org/wiki/Biology_of_bipolar_disorder
*  JCI - Mutations in sodium-channel gene SCN9A cause a spectrum of human genetic pain disorders
In contrast, there is a general failure to develop pain or hypersensitivity in response to inflammatory stimuli, while ... Several of these drugs have shown a degree of efficacy in patients with pain due to mutations in Nav1.7. Some PE patients have ... Instead, researchers rely on behavioral changes of animals such as signs of paw guarding, lifting, and limping. As a ... Patients typically sleep with uncovered feet, often cooled by a fan. Cold alleviates these complaints, and some patients search ...
  https://www.jci.org/articles/view/33297
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Moreover, the traditional methods used to determine behavioral responses to noxious thermal stimuli usually lack ... hypersensitivity to normally innocuous stimuli1. Hyperalgesia and allodynia have been studied in many different rodent models ... regions in the dorsal column with high resolution may allow for better optimization of paresthesia-pain overlap in patients. ... Medicine, Issue 23, Experimental pain, experimental inflammation, human, skin, heat stimuli, mechanical stimuli, pain threshold ...
  https://www.jove.com/visualize/abstract/24147079/inhibition-glycogen-synthase-kinase-3-prevents-remifentanil-induced
*  Protocols and Video Articles Authored by Samuel L. Drennan
... how ripple stimuli are processed in the central auditory system and how their neural representation contributes to behavioral ... Approximately 30% of patients discharged home from ED had similar risk profiles to admitted patients. ... The authors conclude by discussing 4 types of hypersensitivity reactions, serum sickness in particular, and the chimeric nature ... Through April 2008, 14 508 patients have been auto-assigned to a clinic; on average 320 patients were assigned monthly. A total ...
  https://www.jove.com/author/Samuel+L._Drennan
*  TNF-α and neuropathic pain - a review | Journal of Neuroinflammation | Full Text
... into peripheral sensitization and central sensitization of the nervous system in response to the nociceptive stimuli. Animal ... in relation to the stimuli. At time of this writing, there is as yet no common consensus about the etiology of neuropathic pain ... Neuropathic pain is characterized by disproportionate hypersensitivity to stimuli (hyperalgesia), abnormal pins-and-needles or ... From a behavioral standpoint, nociception is an adaptive tool for better survival, while neuropathic pain is considered ...
  https://jneuroinflammation.biomedcentral.com/articles/10.1186/1742-2094-7-27