*  Bcl-2 - Wikipedia
These pro-apoptotic proteins are in turn activated by BH3-only proteins, and are inhibited by the function of BCL-2 and its ... This is the first FDA approval of a protein-protein inhibitor of BCL-2. Bcl-2 has been shown to interact with: BAK1, BCAP31, ... Tagami S, Eguchi Y, Kinoshita M, Takeda M, Tsujimoto Y (Nov 2000). "A novel protein, RTN-XS, interacts with both Bcl-XL and Bcl ... encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L)". The ...
  https://en.wikipedia.org/wiki/Bcl-2
*  Bcl-2 homologous antagonist killer - Wikipedia
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act ... "Entrez Gene: BAK1 BCL2-antagonist/killer 1". Westphal D, Kluck RM, Dewson G (Feb 2014). "Building blocks of the apoptotic pore ... As a member of the BCL2 protein family, BAK1 functions as a pro-apoptotic regulator involved in a wide variety of cellular ... BAK1 has been shown to interact with: BCL2-like 1, Bcl-2, MCL1, P53, Casp8p41, VDAC2, Mtx2, Mcl-1, Bid, Bim, and Puma. GRCh38: ...
  https://en.wikipedia.org/wiki/Bcl-2_homologous_antagonist_killer
*  List of MeSH codes (D12.644) - Wikipedia
... bcl-x protein MeSH D12.644.360.075.718.968 --- bh3 interacting domain death agonist protein MeSH D12.644.360.100 --- ca(2+)- ... bcl-associated death protein MeSH D12.644.360.075.718.400 --- bcl-2-associated x protein MeSH D12.644.360.075.718.750 --- bcl-2 ... homologous antagonist-killer protein MeSH D12.644.360.075.718.937 --- ... x-linked inhibitor of apoptosis protein MeSH D12.644.360.075.718 --- proto-oncogene proteins c-bcl-2 MeSH D12.644.360.075. ...
  https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D12.644)
*  Photoactivated peptide - Wikipedia
Chemistry portal Biology portal Photochromism Azobenzene Spiropyran Diarylethene Photodynamic therapy Bcl-2 Bak (Bcl-2 ... homologous antagonist killer) Bid (BH3 interacting-domain death agonist) Luis Moroder, G. Andrew Woolley, Rudolf K. Allemann, ... "Reversible Photocontrol of DNA Binding by a Designed GCN4-bZIP Protein". Biochemistry. 45: 6075-6084. doi:10.1021/bi060142r. ...
  https://en.wikipedia.org/wiki/Photoactivated_peptide
*  Cytochrome c - Wikipedia
protein binding. • heme binding. • electron carrier activity. Cellular component. • cytosol. • protein phosphatase type 2A ... BAK1/Bcl-2 homologous antagonist killer. Bcl-2-associated death promoter. Anti-apoptotic:. Bcl-2. Bcl-xL. ... Soltys BJ, Gupta RS (2000). "Mitochondrial proteins at unexpected cellular locations: export of proteins from mitochondria from ... "Effect of constitutive 70-kDa heat shock protein polymerization on its interaction with protein substrate". The Journal of ...
  https://en.wikipedia.org/wiki/Cytochrome_C
*  Caspase 8 - Wikipedia
"Fas-mediated apoptosis in neuroblastoma requires mitochondrial activation and is inhibited by FLICE inhibitor protein and Bcl-2 ... natural killer cell activation. • negative regulation of I-kappaB kinase/NF-kappaB signaling. • TRAIL-activated apoptotic ... protein complex binding. • scaffold protein binding. • protein binding. • identical protein binding. • cysteine-type ... The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD ...
  https://en.wikipedia.org/wiki/CASP8
*  Reactive oxygen species - Wikipedia
In the intrinsic pathway, ROS function to facilitate cytochrome c release by activating pore-stabilizing proteins (Bcl-2 and ... Bcl-xL) as well as inhibiting pore-destabilizing proteins (Bcl-2-associated X protein, Bcl-2 homologous antagonist/killer). The ... The apoptosomes bind to and activate caspase-9, another free-floating protein. The caspase-9 then cleaves the proteins of the ... causing oxidized protein levels to increase. This led researchers to conclude that oxidation of cellular proteins is ...
  https://en.wikipedia.org/wiki/Reactive_oxygen_species
*  List of MeSH codes (D12.776.476) - Wikipedia
... bcl-associated death protein MeSH D12.776.476.075.718.400 -- bcl-2-associated x protein MeSH D12.776.476.075.718.425 -- bcl-2 ... homologous antagonist-killer protein MeSH D12.776.476.075.718.875 -- bcl-x protein MeSH D12.776.476.075.718.937 -- bh3 ... smad1 protein MeSH D12.776.476.024.417.500.200 -- smad2 protein MeSH D12.776.476.024.417.500.300 -- smad3 protein MeSH D12.776. ... smad proteins, inhibitory MeSH D12.776.476.024.417.249.600 -- smad6 protein MeSH D12.776.476.024.417.249.700 -- smad7 protein ...
  https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D12.776.476)
*  Apoptosis - Wikipedia
Many viruses encode proteins that can inhibit apoptosis.[94] Several viruses encode viral homologs of Bcl-2. These homologs can ... such as Natural Killer and cytotoxic T cells) that then induce the infected cell to undergo apoptosis.[89] ... The adenovirus E1B-55K protein and the hepatitis B virus HBx protein are examples of viral proteins that can perform such a ... these inhibitory proteins target retinoblastoma tumor-suppressing proteins.[74] These tumor-suppressing proteins regulate the ...
  https://en.wikipedia.org/wiki/Pro-apoptotic
*  Caspase - Wikipedia
... which is facilitated by binding to adaptor proteins via protein-protein interaction motifs that are collectively referred to as ... BAK1/Bcl-2 homologous antagonist killer. Bcl-2-associated death promoter. Anti-apoptotic:. Bcl-2. Bcl-xL. ... 7 (2): 99-109. doi:10.1038/nrmicro2070. PMC 2910423 . PMID 19148178.. *^ a b c d e f Eldridge, Matthew JG; Shenoy, Avinash R. " ... The adaptor protein FADD will recruit (by a Death domain-Death domain interaction). The other end of the adaptor contains a DED ...
  https://en.wikipedia.org/wiki/Caspase