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*  A Bioinformatics Analysis of Bacterial Type-III Secretion System Genes and Proteins - eTheses Repository
A Bioinformatics Analysis of Bacterial Type-III Secretion System Genes and Proteins. ... T3SSs consist of multiple proteins which assemble to form an apparatus capable of exporting proteins through both membranes of ... Type-III secretion systems (T3SSs) are responsible for the biosynthesis of flagella, and the interaction of many animal and ... Proteins conserved amongst T3SSS can be used for analysis of these systems using computational homology searching. By using ...
  http://etheses.bham.ac.uk/1300/
*  Bacterial type III secretion systems: specialized nanomachines for protein delivery into target cells. - PubMed - NCBI
Bacterial type III secretion systems: specialized nanomachines for protein delivery into target cells.. Galán JE1, Lara-Tejero ... Bacterial type III secretion systems: specialized nanomachines for protein delivery into target cells ... Bacterial type III secretion systems: specialized nanomachines for protein delivery into target cells ... Bacterial type III secretion systems: specialized nanomachines for protein delivery into target cells ...
  https://www.ncbi.nlm.nih.gov/pubmed/25002086?dopt=Abstract
*  NMR STUDIES OF BACTERIAL TYPE III SECRETION APPARATUS NEEDLE AND TIP PROTEINS AND THE NMR STRUCTURE OF THE HANTAVIRUS...
NMR STUDIES OF BACTERIAL TYPE III SECRETION APPARATUS NEEDLE AND TIP PROTEINS AND THE NMR STRUCTURE OF THE HANTAVIRUS ... The type III secretion apparatus (TTSA) functions like a syringe to inject proteins through an external needle and into a ... Many Gram-negative bacterial pathogens utilize type III secretion systems (TTSSs) for subverting the normal cellular functions ... The tip complex is assembled by SipD, the tip protein in Salmonella, and BipD, the tip protein in Burkholderia. We also ...
  https://kuscholarworks.ku.edu/handle/1808/5438
*  Graduate Thesis Or Dissertation | Creation of an efficient protein expression and secretion system in the gram-positive...
Creation of an efficient protein expression and secretion system in the gram-positive bacterial vector, Streptococcus gordonii ... This bacterial expression system takes advantage of the natural pathway of protein export and anchoring on the surface of the ... These proteins were tested for the ability to bind chitin beads and cleave between the target protein and the intein. Results ... In this case, the affinity tag would need to be removed from the target protein. In order to both purify a protein and remove ...
  https://ir.library.oregonstate.edu/concern/graduate_thesis_or_dissertations/cn69m634q
*  Protein secretion systems in bacterial-host associations, and their description in the Gene Ontology
... ... including the processes of bacterial secretion. Here we survey bacterial secretion systems known to modulate interactions with ... Protein secretion plays a central role in modulating the interactions of bacteria with their environments. This is particularly ... A number of secreted proteins are destined to enter the host cell (effectors and toxins), and thus several secretion systems ...
  https://vtechworks.lib.vt.edu/handle/10919/18926
*  Defining Assembly Pathways by Fluorescence Microscopy | SpringerLink
Bacterial secretion systems are among the largest protein complexes in prokaryotes and display remarkably complex architectures ... Bacterial secretion systems are among the largest protein complexes in prokaryotes and display remarkably complex architectures ... Tseng T-T, Tyler B, Setubal J (2009) Protein secretion systems in bacterial-host associations, and their description in the ... In: Journet L., Cascales E. (eds) Bacterial Protein Secretion Systems. Methods in Molecular Biology, vol 1615. Humana Press, ...
  https://link.springer.com/protocol/10.1007%2F978-1-4939-7033-9_23
*  Identification of Effectors: Precipitation of Supernatant Material | SpringerLink
Bacterial secretion systems allow the transport of proteins, called effectors, as well as external machine components in the ... Bacterial secretion systems allow the transport of proteins, called effectors, as well as external machine components in the ... In: Journet L., Cascales E. (eds) Bacterial Protein Secretion Systems. Methods in Molecular Biology, vol 1615. Humana Press, ... Caldwell RB, Lattemann CT (2004) Simple and reliable method to precipitate proteins from bacterial culture supernatant. Appl ...
  https://link.springer.com/protocol/10.1007%2F978-1-4939-7033-9_31
*  Screening for Secretion of the Type VI Secretion System Protein Hcp by Enzyme-Linked Immunosorbent Assay and Colony Blot |...
The T6SS facilitates the secretion and injection of toxic effector proteins into host... ... The bacterial type VI secretion system (T6SS) is a secretory apparatus encoded by many Gram-negative bacteria. ... In: Journet L., Cascales E. (eds) Bacterial Protein Secretion Systems. Methods in Molecular Biology, vol 1615. Humana Press, ... Screening for Secretion of the Type VI Secretion System Protein Hcp by Enzyme-Linked Immunosorbent Assay and Colony Blot. ...
  https://link.springer.com/protocol/10.1007%2F978-1-4939-7033-9_32
*  Use of synthetic signal sequences to explore the protein export machinery. - Semantic Scholar
... for protein secretion are decoded and used to target proteins to the protein machinery that facilitates their translocation ... Of these, signal sequences specify that a protein should be secreted from a cell or incorporated into the cytoplasmic membrane ... We review research on how the information in signal sequences enables their passenger proteins to be correctly and efficiently ... The information for correct localization of newly synthesized proteins in both prokaryotes and eukaryotes resides in self- ...
  https://www.semanticscholar.org/paper/Use-of-synthetic-signal-sequences-to-explore-the-Cl%C3%A9rico-Maki/10afedb2e1bd002c7a2641a8775f83e0bc104ed7
*  A signal peptide peptidase (SPP) reporter activity assay based on the cleavage of type II membrane protein substrates provides...
... designed based on data suggesting that SPP has an orientation distinct from presenilin and cleaves type II membrane proteins, ... Membrane proteases in the bacterial protein secretion and quality control pathway.. *Ross E. Dalbey, Peng Wang, Jan Maarten van ... Signal peptide peptidases: a family of intramembrane-cleaving proteases that cleave type 2 transmembrane proteins.. *Todd E ... A signal peptide peptidase (SPP) reporter activity assay based on the cleavage of type II membrane protein substrates provides ...
  https://www.semanticscholar.org/paper/A-signal-peptide-peptidase-%28SPP%29-reporter-activity-Nyborg-Jansen/215d203f31ddb20dbaf6d16cd18a678cd2cd7dae
*  Role and Function of the Type IV Secretion System in Anaplasma and Ehrlichia Species | Springer for Research & Development
Papanikou E, Karamanou S, Economou A (2007) Bacterial protein secretion through the translocase nanomachine. Nat Rev Microbiol ... Khweek AA, Caution K, Akhter A, Abdulrahman BA, Tazi M, Hassan H et al (2013) A bacterial protein promotes the recognition of ... Niu H, Xiong Q, Yamamoto A, Hayashi-Nishino M, Rikihisa Y (2012) Autophagosomes induced by a bacterial Beclin 1 binding protein ... Rikihisa Y, Lin M (2010) Anaplasma phagocytophilum and Ehrlichia chaffeensis type IV secretion and Ank proteins. Curr Opin ...
  https://rd.springer.com/chapter/10.1007%2F978-3-319-75241-9_12
*  Frontiers | Mycobacterium marinum mmar 2318 and mmar 2319 are Responsible for Lipooligosaccharide Biosynthesis and Virulence...
2006). Identification of a conserved bacterial protein secretion system in Vibrio cholerae using the Dictyostelium host model ... Type VI secretion system translocates a phage tail spike-like protein into target cells where it cross-links actin. Proc. Natl ... Bacterial Strains, Cells, and Growth Conditions. Mycobacterium smegmatis mc2155 and M. marinum NTUH-M6094 (clinically isolated ... The bacterial suspension was plated in six-well (350 μL/well) or 24-well (50 μL) plates containing SM agar (Pan et al., 2011) ...
  https://www.frontiersin.org/articles/10.3389/fmicb.2015.01458/full
*  Biopolymers, Volume 7, Polyamides and Complex Proteinaceous Materials I - Fillers
Cell Membranes: Protein Components and Functions (W. Wimley). Bacterial Protein Secretion and Targeting (A. Driessen, et al.). ... self-assembling proteins, cell membranes, feathers, elastic proteins, silk proteins, adhesive proteins, protein composites, ... Topics included are: poly(g-d-glutamate), cyanophycin, modifications of proteins, sweet-tasting proteins, motor proteins, ... Self-assembling Symmetric Protein Materials (J. Padilla & T. Yu). Self-assembly Protein Systems: Microbial S-layers (U. Sleytr ...
  http://www.chemtec.org/proddetail.php?prod=978-3-527-30222-2&cat=19
*  Diversification of Type VI Secretion System Toxins Reveals Ancient Antagonism among Bee Gut Microbes | mBio
Identification of a conserved bacterial protein secretion system in Vibrio cholerae using the Dictyostelium host model system. ... This study examined the role of type VI secretion systems (T6SSs)-protein complexes used to deliver toxic proteins into ... A widespread bacterial type VI secretion effector superfamily identified using a heuristic approach. Cell Host Microbe 11:538- ... Burkholderia type VI secretion systems have distinct roles in eukaryotic and bacterial cell interactions. PLoS Pathog 6: ...
  https://mbio.asm.org/content/8/6/e01630-17
*  Infectious Diseases | Sackler Faculty of Medicine | Tel Aviv University
Bacterial Protein Secretion Systems and Toxins'. Dr. Dor Salomon, Ph.D. and his lab are identifying novel virulent and ... Host-Virus Interactions in Bacterial Systems'. Prof. Udi Qimron, Ph.D. studies basic aspects of bacteriophage growth with ... Fuad Iraqi, Ph.D. actively identifies and characterizes genes involves in the host response to a variety of bacterial and ... emphasis on the recently identified bacterial defense system, the CRISPR. Our ultimate objective is to identify novel ...
  https://en-med.tau.ac.il/InfectiousDiseases
*  Evaluation of Protein Translocation into Eukaryotic Cells by Yersinia pestis | Springer for Research & Development
Bacterial proteins, whether surface bound or secreted, are crucial for mediating bacterial virulence. Many Gram-negative... ... Protein-protein interactions are important during bacterial pathogenesis. ... Cornelis GR (2000) Type III secretion: a bacterial device for close combat with cells of their eukaryotic host. Philos Trans R ... Protein-protein interactions are important during bacterial pathogenesis. Bacterial proteins, whether surface bound or secreted ...
  https://rd.springer.com/protocol/10.1007%2F978-981-10-7947-4_17
*  Staff Profile - Institute for Cell and Molecular Biosciences - Newcastle University
students on projects that exploit bacterial genetics to study bacterial protein secretion. ... My expertise utilise Bacterial genetics to study fundmental apsects of the bacterial life cycle. My laboratory uses, protein ... The bacterial flagellar protein export apparatus processively transports flagellar proteins even with extremely infrequent ATP ... The rate of protein secretion dictates the temporal dynamics of flagellar gene expression. Molecular Microbiology 2008, 70(4), ...
  http://www.ncl.ac.uk/camb/staff/profile/phillipaldridge.html
*  Type VI secretion requires a dynamic contractile phage tail-like structure
Type VI Secretion Systems (T6SS) are bacterial virulence-associated nanomachines composed of proteins that are evolutionarily ... Identification of a conserved bacterial protein secretion system in Vibrio cholerae using the Dictyostelium host model system. ... Type VI secretion system translocates a phage tail spike-like protein into target cells where it cross-links actin. Proc Natl ... T6SS+ bacterial effector cells are thought to kill target cells through delivery of toxic effector proteins in a cell-cell ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC3527127/?lang=en-ca
*  TIGR01168
2003 May;185(9):2910-9. RN [3] RM PMID:16929299 RT Signal sequence directs localized secretion of bacterial surface proteins. ... RN [2] RM PMID: 12700270 RT The YSIRK-G/S motif of staphylococcal protein A and its role in efficiency of signal peptide ... There is a strong correlation between proteins carrying this region at the N-terminus and those carrying the Gram-positive ... Many surface proteins found in Streptococcus, Staphylococcus, and related lineages share apparently homologous signal sequences ...
  http://www.jcvi.org/cgi-bin/tigrfams/HmmReportPage.cgi?acc=TIGR01168
*  Frontiers | Modulation of Type III Secretion System in Pseudomonas aeruginosa: Involvement of the PA4857 Gene Product |...
... and bacterial motility,whereas chronic infectionsare often associated with biofilm formation and the type VI secretion system ( ... and bacterial motility,whereas chronic infectionsare often associated with biofilm formation and the type VI secretion system ( ... pathogen that causes serious acute or chronic infections in humans.Acute infections typically involve the type Ш secretion ... pathogen that causes serious acute or chronic infections in humans.Acute infections typically involve the type Ш secretion ...
  https://www.frontiersin.org/articles/10.3389/fmicb.2016.00007/full
*  An Intracellular Peptidyl-Prolyl cis/trans Isomerase Is Required for Folding and Activity of the Staphylococcus aureus Secreted...
Bacterial PPIases that are involved in protein secretion typically have more than one target in the cell. In L. monocytogenes, ... The PrsA lipoprotein is essential for protein secretion in Bacillus subtilis and sets a limit for high-level secretion. Mol ... that an intracellular cyclophilin has been implicated in bacterial protein secretion.. The general secretory (Sec) pathway is ... Type I signal peptidase and protein secretion in Staphylococcus aureus. J Bacteriol 194:2677-2686. doi:10.1128/JB.00064-12. ...
  https://jb.asm.org/content/199/1/e00453-16
*  YopN and TyeA Hydrophobic Contacts Required for Regulating Ysc-Yop Type III Secretion Activity by Yersinia pseudotuberculosis
protein-protein interaction, molecular modelling, protein secretion, mutagenesis, bacterial pathogenesis, regulation National ... Yersinia bacteria target Yop effector toxins to the interior of host immune cells by the Ysc-Yop type III secretion system. A ... YopN and TyeA Hydrophobic Contacts Required for Regulating Ysc-Yop Type III Secretion Activity by Yersinia pseudotuberculosis. ... Thus, this YopN C-terminal segment was analyzed for its role in type III secretion control. Bacteria producing YopN truncated ...
  http://umu.diva-portal.org/smash/record.jsf?pid=diva2%3A942392&c=13&searchType=SIMPLE&language=en&query=&af=%5B%5D&aq=%5B%5B%7B%22categoryId%22%3A%2211550%22%7D%5D%5D&aq2=%5B%5B%5D%5D&aqe=%5B%5D&noOfRows=50&sortOrder=author_sort_asc&sortOrder2=title_sort_asc&onlyFullText=false&sf=all
*  CBS Publications
Genome Update: Protein secretion systems in 225 bacterial genomes. Binnewies TT, Bendtsen JD, Hallin PF, Nielsen N, Wassenaar ... Genome opdate: Protein secretion systems in 225 bacterial genomes. Bennewies TT, Bendtsen JD, Hallin PF, Nielsen N, Wassenaar ... Genome update: Prediction of secreted proteins in 225 bacterial proteomes. Bendtsen JD, Binnewies TT, Hallin PF, Sicheritz- ... Functionality of System Components: Conservation of Protein Function in Protein Feature Space. Jensen LJ, Ussery DW, Brunak S. ...
  http://www.cbs.dtu.dk/publications/index.php?userid=517
*  Frontiers | Recognition of Extracellular Bacteria by NLRs and Its Role in the Development of Adaptive Immunity | Immunology
These mechanisms include bacterial secretion systems, pore-forming toxins and outer membrane vesicles. We will then focus on ... These mechanisms include bacterial secretion systems, pore-forming toxins and outer membrane vesicles. We will then focus on ... but also extracellular bacterial pathogens or their components. In this review, we will discuss the various mechanisms used by ... but also extracellular bacterial pathogens or their components. In this review, we will discuss the various mechanisms used by ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2013.00344/full
*  Structures of the C-terminal CLTD subdomains of the Int | Open-i
The bacterial intimins and invasins: a large and novel family of secreted proteins. ... Furthermore, there is little understanding of the molecular events governing secretion of these proteins to the extracellular ... The bacterial intimins and invasins: a large and novel family of secreted proteins. ... Furthermore, there is little understanding of the molecular events governing secretion of these proteins to the extracellular ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3008723_pone.0014403.g007&req=4