*  British Library EThOS: Subversion of Rho GTPases by WxxxE effectors of attaching and effacing pathogens
... and Citrobacter rodentium are constituent members of the attaching and effacing (A/E) pathogens. The A/E group of bacteria are ... Citrobacter rodentium is a murine pathogen which is an excellent animal model for EPEC and EHEC infection. EPEC, EHEC and C. ... A/E pathogens utilise their T3SSs to translocate dozens of effector proteins directly from the bacteria into host cells. Once ... rodentium conserve a genomic region termed the locus of enterocyte effacement (LEE) which encodes a type 3 secretion system ( ...
  http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.523261
*  UniProt: D2THD2 CITRI
Citrobacter rodentium (strain ICC168) (Citrobacter freundii biotype OS 4280). OC Bacteria; Proteobacteria; Gammaproteobacteria ... "The Citrobacter rodentium genome sequence reveals convergent RT evolution with human pathogenic Escherichia coli."; RL J. ... DR KEGG; cro:ROD_01271; -. DR eggNOG; ENOG4105CAX; Bacteria. DR eggNOG; ENOG410XNUJ; LUCA. DR HOGENOM; HOG000221851; -. DR KO; ... Enterobacterales; OC Enterobacteriaceae; Citrobacter. OX NCBI_TaxID=637910 {ECO:0000313,EMBL:CBG86907.1, ECO:0000313,Proteomes: ...
  http://www.genome.jp/dbget-bin/www_bget?uniprot:D2THD2_CITRI
*  Microbiologists discover how gut bacterial resources are hijacked to promote intestinal and foodborne illnesses: December 2014...
UT Southwestern Medical Center microbiologists have identified key bacteria in the gut whose resources are hijacked to spread ... the gut bacterium Citrobacter rodentium. Mice whose gut microbiota consisted solely of B. thetaiotaomicron were more ... Though many E. coli bacteria are harmless and critical to gut health, some E. coli species are harmful and can be spread ... Once again, the research group saw that B. thetaiotaomicron caused changes in the environment that promoted C. rodentium ...
  http://www.utsouthwestern.edu/newsroom/articles/year-2014/ecoli-sperandio.html
*  Product Overview anti-MAP3K8 Antibodies
study to determine whether Tpl2 influences the immune response generated to the extracellular bacterium Citrobacter rodentium, ... expression and neutrophil recruitment during infection with extracellular bacteria ...
  http://www.antibodies-online.com/pi3k-akt-signaling-pathway-4/map3k8-antibody-4103/
*  New study: Traumatic brain injury causes intestinal damage | EurekAlert! Science News
They infected the mice with Citrobacter rodentium, a species of bacteria that is the rodent equivalent of E. coli, which ... Scientists discover gut bacteria in bees spread antibiotic-resistant genes to each other Arizona State University ... In mice with a TBI who were infected with this the bacteria, brain inflammation worsened. Furthermore, in the hippocampus, a ... which is often caused by bacteria, and 2.5 times more likely to die of a digestive system problem, compared with those without ...
  https://eurekalert.org/pub_releases/2017-12/uoms-nst120617.php
*  Frontiers | Beyond NK Cells: The Expanding Universe of Innate Lymphoid Cells | Immunology
ILC3s protect intestinal epithelium in vivo from attaching and effacing bacteria, such as Citrobacter rodentium, a mouse model ... By subtracting these ions to commensal bacteria, IL-22 favors expansion of pathogenic bacteria, such as Salmonella typhimurium ... In the absence of ILC3s, host-derived bacteria of the Alcaligenes species disseminate to peripheral organs and induce systemic ... cytotoxicity receptor NKp46 is dispensable for IL-22-mediated innate intestinal immune defense against Citrobacter rodentium. J ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2014.00282/full
*  Citrobacter rodentium - Wikipedia
Citrobacter rodentium is a Gram-negative species of bacteria. Schauer DB, Zabel BA, Pedraza IF, O'Hara CM, Steigerwalt AG, ... Citrobacter rodentium at the Encyclopedia of Life LPSN Type strain of Citrobacter rodentium at BacDive - the Bacterial ... Mundy R, MacDonald TT, Dougan G, Frankel G, Wiles S (2005). "Citrobacter rodentium of mice and man". Cell Microbiol. 7 (12): ... Bhinder G, Sham HP, Chan JM, Morampudi V, Jacobson K, Vallance BA (2013). "The Citrobacter rodentium mouse model: studying ...
  https://en.wikipedia.org/wiki/Citrobacter_rodentium
*  Protocols and Video Articles Authored by Bruce A. Vallance
The Citrobacter rodentium Mouse Model: Studying Pathogen and Host Contributions to Infectious Colitis', 'DNBS/TNBS Colitis ... Using Citrobacter rodentium, a mouse-adapted A/E bacterium, we found that Î"nleC and wild-type C. rodentium-infected mice ... Using Citrobacter rodentium, a mouse-adapted A/E bacterium, we found that Map colocalized with host cell mitochondria, and that ... we infected mice with Citrobacter rodentium, a mouse-adapted attaching and effacing (A/E) bacterium that infects colonic ...
  https://www.jove.com/author/Bruce+A._Vallance
*  Microbiota, Immune Subversion, and Chronic Inflammation
... mutants were outcompeted by wild-type bacteria in germ-free mice only in the presence of inflammatory Citrobacter rodentium ... Gut bacteria require neutrophils to promote mammary tumorigenesis. Oncotarget (2015) 6:9387-96.10.18632/oncotarget.3328 [PMC ... Several Gram-negative bacteria that express immune-evasive lipid A species are associated with an increased risk of ... Gram negative bacteria increase non-small cell lung cancer metastasis via toll-like receptor 4 activation and mitogen-activated ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC5346547/
*  Findings | Science
VANCOUVER, CANADA-Infect some strains of lab mice with the pathogen Citrobacter rodentium and they die, yet other strains ... Boosting and then cutting back their diet caused mice with gut bacteria from the child with kwashiorkor to lose and then gain ... Citrobacter caused severe diarrhea in these rodents. The researchers found that the shift in the microbial makeup reduced by ... When infected with Citrobacter, the once vulnerable rodents lived to tell the tale, Finlay reported at the International Human ...
  http://science.sciencemag.org/content/331/6023/findings
*  Molecular explanation for the contradiction between systemic Th17 defect and localized bacterial infection in hyper-IgE...
... and Citrobacter rodentium, which are rarely observed in HIES patients (16, 17, 20, 21, 36, 37). The reason for this difference ... Most patients suffer from recurrent infections by fungi and bacteria, predominantly the Gram-positive bacteria S. aureus. The ... 2, B and C). When bacteria were cultured with the culture supernatant from keratinocytes stimulated by control T cells, the ... and mice that do not produce IL-22 are susceptible to lung infection by the Gram-negative bacteria Klebsiella pneumoniae and ...
  http://jem.rupress.org/content/206/6/1291
*  Cellular and Molecular Gastroenterology and Hepatology
... and the mouse pathogen Citrobacter rodentium. These bacteria, which infect the intestinal epithelium, activate a syringe-like ... such as translocation of bacteria across the epithelium. ...
  https://www.gastro.org/journals-and-publications/cellular-and-molecular-gastroenterology-and-hepatology
*  JCI - Commensal Propionibacterium strain UF1 mitigates intestinal inflammation via Th17 cell regulation
... or pathogenic bacteria (e.g., Citrobacter rodentium) (18), demonstrates the same trend due to the lack of competitive commensal ... bacteria.. Figure 2. Characterization of P. UF1 bacterium. (A) Genome sequence comparison of isolated P. UF1 with known P. ... The enriched bacteria, via bead complex, were spread over several MRS-lactate agar plates (MRS agar with 1% sodium lactate; w/v ... C) Phylum structure of the abundant bacteria in fecal samples of HBMF and FF preterm infants on days 21 ± 3. (D) Taxonomic ...
  https://hzyouma.com.www.mobile.jci.org/articles/view/95376
*  10 Best Probiotics For Depression & Anxiety: Gut-Brain Axis Modification
Citrobacter rodentium: This is a Gram-negative bacterium that is associated with higher mortality rates in mice. Whether ... Introducing healthy bacteria in your gut should help kill off some of the bad bacteria and prevent D-lactic acid build-up from ... A study from 2006 found that when mice were infected with Citrobacter rodentium, early-stages of the infection were associated ... That said, it is unlikely that Citrobacter rodentium solely causes memory deficits - it may also directly increase anxiety in ...
  http://mentalhealthdaily.com/2016/03/01/10-best-probiotics-for-depression-anxiety-gut-brain-axis-modification/
*  Host fucosylation increases tolerance of a pathogena, D | Open-i
... rodentium-infected and uninfected mice (mean±s.e.m.; ... Citrobacter rodentium. Four days after infection, mice were ... as shown by reporter bacteria and community-wide analysis of microbial gene expression. Fucose affects the expression of ... It also improves host tolerance of the mild pathogen Citrobacter rodentium. Thus, rapid IEC fucosylation appears to be a ... It also improves host tolerance of the mild pathogen Citrobacter rodentium. Thus, rapid IEC fucosylation appears to be a ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4214913_nihms-625847-f0004&req=4
*  Requirement of epithelial integrin-linked kinase for facilitation of Citrobacter rodentium-induced colitis | BMC...
C rodentium (strain DBS 100) was given by gavage as an inoculum of 2.5 × 108 bacteria per 100 ul of Luria broth and the mice ... C. rodentium-induced colitis is attenuated in ILK-ko mice, and ILK is induced in response to infection. The C. rodentium ... MacDonald TT, Frankel G, Dougan G, Goncalves NS, Simmons C: Host defences to citrobacter rodentium. Int J Med Microbiol. 2003, ... Here we report on the role of epithelial derived ILK in response to Citrobacter rodentium infection. ...
  https://bmcgastroenterol.biomedcentral.com/articles/10.1186/1471-230X-13-137
*  Transplanted human fecal microbiota enhanced Guillain Barré syndrome autoantibody responses after Campylobacter jejuni...
16S rRNA gene), Citrobacter rodentium (espB gene), and Enterococcus faecalis (ddl gene). Dedicated sentinel mice were used to ... Molecular mimicry revisited: gut bacteria and multiple sclerosis. J Clin Microbiol. 2006;44(6):2099-104.View ArticlePubMed ... a TH2-associated antibody bias in Humicrobiota mice that was not associated with the presence of the inoculating bacterium (Fig ... retained a microbiota distinct from that of their Convmicrobiota counterparts that could be primarily distinguished by bacteria ...
  https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-017-0284-4
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... as well as the methods used to characterize Citrobacter rodentium infection in mice. C. rodentium is a gram negative, murine ... C. rodentium induced colitis is one such rare model that allows for the analysis of host responses to enteric bacteria, ... The Citrobacter rodentium Mouse Model: Studying Pathogen and Host Contributions to Infectious Colitis ... In addition, the diet-mediated effects were evident in a gastrointestinal infection model (Citrobacter rodentium) and in ...
  https://www.jove.com/visualize/abstract/24489720/dominant-effects-diet-on-microbiome-local-systemic-immune-response
*  Identification of Novel Components Influencing Colonization Factor Antigen I Expression in Enterotoxigenic Escherichia coli
... and functions as an environmental cue for both Vibrio cholerae and Citrobacter rodentium, though it has no effect on either CS5 ... Erythrocytes were stored for up to 2 weeks at 4°C. Bacteria were serially diluted in 25 μL DPBS-M in 96-well round bottom ... from Citrobacter rodentium. Mol Microbiol 68: 314-327. pmid:18284589 * View Article ... 9. Merritt ME, Donaldson JR (2009) Effect of bile salts on the DNA and membrane integrity of enteric bacteria. J Med Microbiol ...
  http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0141469
*  JoVE Author Search: Cadwell K
Citrobacter, Citrobacter Rodentium, Crohns Disease, Disease, Environment, Gene, Genes, Infections, Inflammatory Bowel Disease, ... Research Interests: Autophagy, Bacteria, Bacterial Infections, Citrobacter, Citrobacter Rodentium, Crohns Disease, Disease, ... Defining the role of Nod2 and bacteria in Atg16L1-dependent intestinal disease.. ...
  http://labindex.jove.com/author/Cadwell-K
*  Human Th17 cells | Arthritis Research & Therapy | Full Text
Citrobacter rodentium, Escherichia coli, Borrelia burgdoferi and fungal species, whereas IL-17 appears to play a modest role ( ... This results in granulocyte recruitment, which plays an important role in protection against extracellular bacteria but also in ... Th17 cells have been suggested to play an important role in responses against extracellular Gram-negative bacteria and fungi, ...
  https://arthritis-research.biomedcentral.com/articles/10.1186/ar2392
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... as well as the methods used to characterize Citrobacter rodentium infection in mice. C. rodentium is a gram negative, murine ... C. rodentium induced colitis is one such rare model that allows for the analysis of host responses to enteric bacteria, ... The Citrobacter rodentium Mouse Model: Studying Pathogen and Host Contributions to Infectious Colitis ... Bacteria, Bacterial Infections and Mycoses, bacteria, infection, viability, fluorescence microscopy, cell, imaging ...
  https://www.jove.com/visualize/abstract/22046438/bacterial-epithelial-contact-is-key-determinant-host-innate-immune
*  Frontiers | Hypothermia Promotes Interleukin-22 Expression and Fine-Tunes Its Biological Activity | Immunology
... which include intestinal Citrobacter rodentium (7) as well as lung Klebsiella pneumonia (8) and influenza infections (9), ... local IL-22 is supposed to prevent translocation of pathogenic bacteria that otherwise pose a risk for sepsis development (16 ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2017.00742/full
*  Helminthic Therapy: Using Worms to Treat Immune-Mediated Disease | SpringerLink
Concurrentinfection withan intestinal helminth parasite impairs host resistance to enteric Citrobacter rodentium and enhances ... Resident enteric bacteria are necessary for development of spontaneous colitis and immunesystem activation in interleukin-10- ... Citrobacter-induced colitis in mice. Infect Immun 2005; 73(9):5468-5481.CrossRefPubMedGoogle Scholar ...
  https://link.springer.com/chapter/10.1007/978-1-4419-1601-3_12
*  MH-Hannover: Profiles
Mechanisms of dendritic cell mediated recognition and immune regulation in intestinal infections with Citrobacter rodentium ... Topic: Influence of intestinal bacteria on the antibody repertoire of B-1 cells.. Supervisor: Dr. Siegfried Weiss, Research ... Research Topic: Dynamic interaction between bacteria and the intestinal barrier. Supervisor: Prof. Dr. André Bleich, Central ... Topic: Role of type I interferons in the innate and adaptive immune defense against Gram-negative bacteria ...
  https://www.mh-hannover.de/zib_alumni_profiles.html