*  British Library EThOS: Subversion of Rho GTPases by WxxxE effectors of attaching and effacing pathogens
... and Citrobacter rodentium are constituent members of the attaching and effacing (A/E) pathogens. The A/E group of bacteria are ... Citrobacter rodentium is a murine pathogen which is an excellent animal model for EPEC and EHEC infection. EPEC, EHEC and C. ... A/E pathogens utilise their T3SSs to translocate dozens of effector proteins directly from the bacteria into host cells. Once ... rodentium conserve a genomic region termed the locus of enterocyte effacement (LEE) which encodes a type 3 secretion system ( ...
  http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.523261
*  Microbiologists discover how gut bacterial resources are hijacked to promote intestinal and foodborne illnesses: December 2014...
UT Southwestern Medical Center microbiologists have identified key bacteria in the gut whose resources are hijacked to spread ... the gut bacterium Citrobacter rodentium. Mice whose gut microbiota consisted solely of B. thetaiotaomicron were more ... Though many E. coli bacteria are harmless and critical to gut health, some E. coli species are harmful and can be spread ... Once again, the research group saw that B. thetaiotaomicron caused changes in the environment that promoted C. rodentium ...
  http://www.utsouthwestern.edu/newsroom/articles/year-2014/ecoli-sperandio.html
*  Publishers of academic thesis & dissertations. Free search & preview. PDF downloads. Instant access to paperback & ebook...
... that Zbtb46+ Notch2-dependent cDCs were specifically required for survival after infection with the enterohemorrhagic bacterium ... Citrobacter rodentium. Following infection, CD11b+ cDCs were required for the induction of anti-microbial peptides from ... cDCs were specifically required for survival after infection with the enterohemorrhagic bacterium Citrobacter rodentium. ...
  http://www.dissertation.com/abstracts/2045417
*  The battle in the body: Watch as an infection takes hold before it is beaten back by the immune system | Daily Mail Online
The team from Imperial College London used a version of the bacteria 'Citrobacter rodentium', which they had genetically ... By day 12 the battle was over and no more Citrobacter rodentium is visible in scans. The mouse has effectively recovered from ... He added: 'The infection of mice with Citrobacter rodentium is an excellent model to study infection with E. coli 0157 in ... They charted the bacteria's course by analysing the tiny amounts of light that escaped from the animal. More light meant there ...
  https://www.dailymail.co.uk/health/article-2167607/The-battle-body-Watch-infection-takes-hold-beaten-immune-system.html
*  Product Overview anti-MAP3K8 Antibodies
study to determine whether Tpl2 influences the immune response generated to the extracellular bacterium Citrobacter rodentium, ... expression and neutrophil recruitment during infection with extracellular bacteria ...
  http://www.antibodies-online.com/pi3k-akt-signaling-pathway-4/map3k8-antibody-4103/
*  New study: Traumatic brain injury causes intestinal damage | EurekAlert! Science News
They infected the mice with Citrobacter rodentium, a species of bacteria that is the rodent equivalent of E. coli, which ... Scientists discover gut bacteria in bees spread antibiotic-resistant genes to each other Arizona State University ... In mice with a TBI who were infected with this the bacteria, brain inflammation worsened. Furthermore, in the hippocampus, a ... which is often caused by bacteria, and 2.5 times more likely to die of a digestive system problem, compared with those without ...
  https://eurekalert.org/pub_releases/2017-12/uoms-nst120617.php
*  Frontiers | In Silico Screening of the Human Gut Metaproteome Identifies Th17-Promoting Peptides Encrypted in Proteins of...
Indeed presence of these bacteria confers resistance to the intestinal pathogen Citrobacter rodentium (Ivanov et al., 2009). ... in vivo studies suggest that infection by Citrobacter rodentium in IL-23 -/- mice can be prevented by transferring Th22 but not ... 2015). Induction of Th17 cells by segmented filamentous bacteria in the murine intestine. J. Immunol. Methods 421, 104-111. doi ... 2013). Role of sortase-dependent pili of Bifidobacterium bifidum PRL2010 in modulating bacterium-host interactions. Proc. Natl ...
  https://www.frontiersin.org/articles/10.3389/fmicb.2017.01726/full
*  Frontiers | Beyond NK Cells: The Expanding Universe of Innate Lymphoid Cells | Immunology
ILC3s protect intestinal epithelium in vivo from attaching and effacing bacteria, such as Citrobacter rodentium, a mouse model ... By subtracting these ions to commensal bacteria, IL-22 favors expansion of pathogenic bacteria, such as Salmonella typhimurium ... In the absence of ILC3s, host-derived bacteria of the Alcaligenes species disseminate to peripheral organs and induce systemic ... cytotoxicity receptor NKp46 is dispensable for IL-22-mediated innate intestinal immune defense against Citrobacter rodentium. J ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2014.00282/full
*  Citrobacter rodentium - Wikipedia
Citrobacter rodentium is a Gram-negative species of bacteria. Schauer DB, Zabel BA, Pedraza IF, O'Hara CM, Steigerwalt AG, ... Citrobacter rodentium at the Encyclopedia of Life LPSN Type strain of Citrobacter rodentium at BacDive - the Bacterial ... Mundy R, MacDonald TT, Dougan G, Frankel G, Wiles S (2005). "Citrobacter rodentium of mice and man". Cell Microbiol. 7 (12): ... Bhinder G, Sham HP, Chan JM, Morampudi V, Jacobson K, Vallance BA (2013). "The Citrobacter rodentium mouse model: studying ...
  https://en.wikipedia.org/wiki/Citrobacter_rodentium
*  Citrobacter rodentium | Harvard Catalyst Profiles | Harvard Catalyst
A species of gram-negative bacteria in the genus CITROBACTER, family ENTEROBACTERIACEAE. As an important pathogen of laboratory ... "Citrobacter rodentium" by people in Harvard Catalyst Profiles by year, and whether "Citrobacter rodentium" was a major or minor ... "Citrobacter rodentium" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical ... Virulence factors enhance Citrobacter rodentium expansion through aerobic respiration. Science. 2016 09 16; 353(6305):1249-53. ...
  https://connects.catalyst.harvard.edu/Profiles/display/Concept/Citrobacter%20rodentium
*  UniProt: D2THD2 CITRI
Citrobacter rodentium (strain ICC168) (Citrobacter freundii biotype OS 4280). OC Bacteria; Proteobacteria; Gammaproteobacteria ... "The Citrobacter rodentium genome sequence reveals convergent RT evolution with human pathogenic Escherichia coli."; RL J. ... DR KEGG; cro:ROD_01271; -. DR eggNOG; ENOG4105CAX; Bacteria. DR eggNOG; ENOG410XNUJ; LUCA. DR HOGENOM; HOG000221851; -. DR KO; ... Enterobacterales; OC Enterobacteriaceae; Citrobacter. OX NCBI_TaxID=637910 {ECO:0000313,EMBL:CBG86907.1, ECO:0000313,Proteomes: ...
  http://www.genome.jp/dbget-bin/www_bget?uniprot:D2THD2_CITRI
*  Protocols and Video Articles Authored by Grady E. Carlson (Translated to Chinese)
Gram-negative bacteria including Escherichia coli, Citrobacter rodentium, Salmonella typhimurium, and Shigella flexneri are ... Sep, 2013 , Pubmed ID: 23810904 Gram-negative bacteria possess an outer membrane envelope consisting of an outer leaflet of ... Here we report that the purified human recombinant (r) CST-9 protects against the deadly bacterium Francisella tularensis (Ft) ... Additionally, we demonstrated that Entamoeba histolytica prefers to engulf bacteria with intact LPS and that this engulfment ...
  https://www.jove.com/author/Grady+E._Carlson?language=Chinese
*  High-fiber diet keeps gut microbes from eating colon's lining, protects against infection | EurekAlert! Science News
... eroding it to the point where dangerous invading bacteria can infect the colon wall, new research in mice shows. ... When the researchers infected the mice with Citrobacter rodentium - the E. coli-like bacteria - they observed that these ... And the four bacteria strains that flourished most in low-fiber and no-fiber conditions were the only ones that make enzymes ... He also notes the role of U-M colleagues led by Gabriel Nunez and Nobuhiko Kamada in providing the C. rodentium pathogen model ...
  https://www.eurekalert.org/pub_releases/2016-11/uomh-hdk111416.php
*  Protocols and Video Articles Authored by Bruce A. Vallance
The Citrobacter rodentium Mouse Model: Studying Pathogen and Host Contributions to Infectious Colitis', 'DNBS/TNBS Colitis ... Using Citrobacter rodentium, a mouse-adapted A/E bacterium, we found that Î"nleC and wild-type C. rodentium-infected mice ... Using Citrobacter rodentium, a mouse-adapted A/E bacterium, we found that Map colocalized with host cell mitochondria, and that ... we infected mice with Citrobacter rodentium, a mouse-adapted attaching and effacing (A/E) bacterium that infects colonic ...
  https://www.jove.com/author/Bruce+A._Vallance
*  Findings | Science
VANCOUVER, CANADA-Infect some strains of lab mice with the pathogen Citrobacter rodentium and they die, yet other strains ... Boosting and then cutting back their diet caused mice with gut bacteria from the child with kwashiorkor to lose and then gain ... Citrobacter caused severe diarrhea in these rodents. The researchers found that the shift in the microbial makeup reduced by ... When infected with Citrobacter, the once vulnerable rodents lived to tell the tale, Finlay reported at the International Human ...
  http://science.sciencemag.org/content/331/6023/findings
*  Molecular explanation for the contradiction between systemic Th17 defect and localized bacterial infection in hyper-IgE...
... and Citrobacter rodentium, which are rarely observed in HIES patients (16, 17, 20, 21, 36, 37). The reason for this difference ... Most patients suffer from recurrent infections by fungi and bacteria, predominantly the Gram-positive bacteria S. aureus. The ... 2, B and C). When bacteria were cultured with the culture supernatant from keratinocytes stimulated by control T cells, the ... and mice that do not produce IL-22 are susceptible to lung infection by the Gram-negative bacteria Klebsiella pneumoniae and ...
  http://jem.rupress.org/content/206/6/1291
*  Cellular and Molecular Gastroenterology and Hepatology
... and the mouse pathogen Citrobacter rodentium. These bacteria, which infect the intestinal epithelium, activate a syringe-like ... such as translocation of bacteria across the epithelium. ...
  https://www.gastro.org/journals-and-publications/cellular-and-molecular-gastroenterology-and-hepatology
*  JCI - Commensal Propionibacterium strain UF1 mitigates intestinal inflammation via Th17 cell regulation
... or pathogenic bacteria (e.g., Citrobacter rodentium) (18), demonstrates the same trend due to the lack of competitive commensal ... bacteria.. Figure 2. Characterization of P. UF1 bacterium. (A) Genome sequence comparison of isolated P. UF1 with known P. ... The enriched bacteria, via bead complex, were spread over several MRS-lactate agar plates (MRS agar with 1% sodium lactate; w/v ... C) Phylum structure of the abundant bacteria in fecal samples of HBMF and FF preterm infants on days 21 ± 3. (D) Taxonomic ...
  https://hzyouma.com.www.mobile.jci.org/articles/view/95376
*  10 Best Probiotics For Depression & Anxiety: Gut-Brain Axis Modification
Citrobacter rodentium: This is a Gram-negative bacterium that is associated with higher mortality rates in mice. Whether ... Introducing healthy bacteria in your gut should help kill off some of the bad bacteria and prevent D-lactic acid build-up from ... A study from 2006 found that when mice were infected with Citrobacter rodentium, early-stages of the infection were associated ... That said, it is unlikely that Citrobacter rodentium solely causes memory deficits - it may also directly increase anxiety in ...
  http://mentalhealthdaily.com/2016/03/01/10-best-probiotics-for-depression-anxiety-gut-brain-axis-modification/
*  Host fucosylation increases tolerance of a pathogena, D | Open-i
... rodentium-infected and uninfected mice (mean±s.e.m.; ... Citrobacter rodentium. Four days after infection, mice were ... as shown by reporter bacteria and community-wide analysis of microbial gene expression. Fucose affects the expression of ... It also improves host tolerance of the mild pathogen Citrobacter rodentium. Thus, rapid IEC fucosylation appears to be a ... It also improves host tolerance of the mild pathogen Citrobacter rodentium. Thus, rapid IEC fucosylation appears to be a ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4214913_nihms-625847-f0004&req=4
*  Requirement of epithelial integrin-linked kinase for facilitation of Citrobacter rodentium-induced colitis | BMC...
C rodentium (strain DBS 100) was given by gavage as an inoculum of 2.5 × 108 bacteria per 100 ul of Luria broth and the mice ... C. rodentium-induced colitis is attenuated in ILK-ko mice, and ILK is induced in response to infection. The C. rodentium ... MacDonald TT, Frankel G, Dougan G, Goncalves NS, Simmons C: Host defences to citrobacter rodentium. Int J Med Microbiol. 2003, ... Here we report on the role of epithelial derived ILK in response to Citrobacter rodentium infection. ...
  https://bmcgastroenterol.biomedcentral.com/articles/10.1186/1471-230X-13-137
*  JCI - Gut microbiome, obesity, and metabolic dysfunction
Antibiotic treatment alters the colonic mucus layer and predisposes the host to exacerbated citrobacter rodentium-induced ... Role of intestinal bacteria in gliadin-induced changes in intestinal mucosa: study in germ-free rats. PLoS One. 2011;6(1): ... as treatment with metronidazole reduces mucus thickness and thereby predisposes mice to exacerbated Citrobacter rodentium- ... Polysaccharide utilization by gut bacteria: potential for new insights from genomic analysis. Nat Rev Microbiol. 2008;6(2):121- ...
  https://www.jci.org/articles/view/58109
*  Transplanted human fecal microbiota enhanced Guillain Barré syndrome autoantibody responses after Campylobacter jejuni...
16S rRNA gene), Citrobacter rodentium (espB gene), and Enterococcus faecalis (ddl gene). Dedicated sentinel mice were used to ... Molecular mimicry revisited: gut bacteria and multiple sclerosis. J Clin Microbiol. 2006;44(6):2099-104.View ArticlePubMed ... a TH2-associated antibody bias in Humicrobiota mice that was not associated with the presence of the inoculating bacterium (Fig ... retained a microbiota distinct from that of their Convmicrobiota counterparts that could be primarily distinguished by bacteria ...
  https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-017-0284-4
*  cortisol Archives - Geospatial Ecology of Marine Megafauna Laboratory
... disrupts commensal microbial populations in the intestines and leads to increased colonization by Citrobacter rodentium. ... Colonization of facultative bacteria (i.e., aerobic bacteria) begins at birth [3], and later, anaerobic bacteria also colonizes ... causing the bacteria to cross the epithelial barrier (reducing the overall numbers of bacteria in the gut), activating immune ... Are bacteria important? What do we get by analyzing microbiomes?. By Leila Lemos, PhD candidate, Fisheries and Wildlife ...
  http://blogs.oregonstate.edu/gemmlab/?tag=cortisol
*  Helminthic Therapy: Using Worms to Treat Immune-Mediated Disease | SpringerLink
Concurrentinfection withan intestinal helminth parasite impairs host resistance to enteric Citrobacter rodentium and enhances ... Resident enteric bacteria are necessary for development of spontaneous colitis and immunesystem activation in interleukin-10- ... Citrobacter-induced colitis in mice. Infect Immun 2005; 73(9):5468-5481.CrossRefPubMedGoogle Scholar ...
  https://link.springer.com/chapter/10.1007/978-1-4419-1601-3_12