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*  International Journal of Pharmaceutical Sciences and Drug Research 2014; 6(4): 253-262
Hutchinson-Gilford progeria syndrome: report of a Libyan family and evidence of autosomal recessive inheritance. Clin Genet. ... Kieras FJ, Brown WT, Houck GE, Zebrower M. Elevation of urinary hyaluronic acid in Werner syndrome and progeria. Biochem Med ... IJPSPP Hutchinson-Gilford Progeria Syndrome: A Prematurely Aging Disorder Ahsas Goyal*, Neetu Agrawal, Bhupesh C. Semwal, ... Majority of affected patients show an autosomal dominant inheritance, although some cases of autosomal recessive inheritance ...
  http://spotidoc.com/doc/318324/international-journal-of-pharmaceutical-sciences-and-drug...
*  Progeroid syndromes - Wikipedia
Main article: Werner syndrome. Werner syndrome (WS) is a rare autosomal recessive disorder.[9][10] It has a global incidence ... Werner syndrome[edit]. Werner syndrome is inherited in an autosomal recessive manner, which means both parents must contribute ... Bloom syndrome[edit]. Main article: Bloom syndrome. Bloom syndrome (BS) is a very rare autosomal recessive disorder.[21] ... Rothmund-Thomson syndrome[edit]. autosomal recessive. Cancer[edit]. Some segmental progeroid syndromes, such as Werner syndrome ...
  https://en.wikipedia.org/wiki/Accelerated_aging_disease
*  anti-WHIP antibody [C1C3] | GeneTex
Werner helicase interacting protein 1) for WB. Anti-WHIP pAb (GTX107101) is tested in Human samples. 100% Ab-Assurance. ... Werner helicase interacting protein 1. Background. Werner's syndrome is a rare autosomal recessive disorder characterized by ... The protein encoded by this gene interacts with the N-terminal portion of Werner protein containing the exonuclease domain. ... FLJ22526 antibody, RP11-420G6.2 antibody, WHIP antibody, bA420G6.2 antibody, WRNIP1 antibody, werner helicase-interacting ...
  http://www.genetex.com/WHIP-antibody-C1C3-GTX107101.html
*  WRNIP1 - Wikipedia
Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. The protein encoded by this gene ... WRNIP1 has been shown to interact with Werner syndrome ATP-dependent helicase. GRCh38: Ensembl release 89: ENSG00000124535 - ... "A novel protein interacts with the Werner's syndrome gene product physically and functionally". J Biol Chem. 276 (23): 20364-9 ... "Entrez Gene: WRNIP1 Werner helicase interacting protein 1". Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to ...
  https://en.wikipedia.org/wiki/WRNIP1
*  WRN monoclonal antibody (M09), clone 3C11 - (H00007486-M09) - Products - Abnova
Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging. [ ...
  http://www.abnova.com/products/products_detail.asp?catalog_id=H00007486-M09
*  Progeroid syndromes - Wikipedia
Werner syndrome (WS) is a rare autosomal recessive disorder. It has a global incidence rate of less than 1 in 100,000 live ... autosomal recessive Some segmental progeroid syndromes, such as Werner syndrome (WS), Bloom syndrome (BS), Rothmund-Thomson ... Hutchinson-Gilford progeria syndrome, Werner syndrome, and Cockayne syndrome are the three genetic disorders in which patients ... Wiedemann-Rautenstrauch (WR) syndrome, also known as neonatal progeroid syndrome, is an autosomal recessive progeroid syndrome ...
  https://en.wikipedia.org/wiki/Progeroid_syndromes
*  Pregnancy sub-cluster 61
Werner's syndrome (WS) is a rare autosomal recessive disorder, characterised by skin changes prematurely during adolescence. An ... Dermatosparaxis Ehlers-Danlos syndrome (or EDS VIIC), a rare autosomal recessive connective tissue disorder, is characterized ... Carney complex is a rare, autosomal-dominant, multisystem disorder characterized by endocrine overactivity, spotty skin ... Carney Complex: A Rare Cause of Cushing Syndrome in Pregnancy. Spaniol Lt Alison LA Departments of Obstetrics and Gynecology, ...
  http://www.biomedsearch.com/cluster/69/Pregnancy/sub-61.html
*  Journal of Alzheimer's Disease - Volume 6, issue 6 - Journals - IOS Press
Werner syndrome (WS) is a rare autosomal recessive disorder characterized as a segmental progeroid syndrome. The gene (WRN) was ... Keywords: Alzheimer's disease, Werner syndrome, WRN 1367 polymorphisms, risk factor, association study ... is the most common neurodegenerative disorder in the elderly and is also considered a progeroid genetic syndrome. The etiology ... Werner helicase polymorphism is not associated with Alzheimer's disease Authors: Payão, Spencer Luiz Marques , de Labio, Roger ...
  https://content.iospress.com/journals/journal-of-alzheimers-disease/6/6
*  POLD1 - Wikipedia
The WRN gene is mutated in Werner syndrome (an autosomal recessive disorder) leading to accelerated aging and increased genetic ... MDPL/MDP, AWS and Werner's syndrome all present with progeria. A first example of germline transmission was observed in a ... Kamath-Loeb AS, Shen JC, Schmitt MW, Loeb LA (April 2012). "The Werner syndrome exonuclease facilitates DNA degradation and ... Oshima J, Sidorova JM, Monnat RJ (March 2016). "Werner syndrome: Clinical features, pathogenesis and potential therapeutic ...
  https://en.wikipedia.org/wiki/POLD1
*  Ageing Research Reviews
Abstract Werner syndrome (WS) is a heritable autosomal recessive human disorder characterized by the premature onset of several ... Werner syndrome (WRN) gene variants and their association with altered function and age-associated diseases.. ... However, despite being the most prevalent neurodegenerative disorder, the number one communication disorder, and one of the top ... B, Valdiglesias V Abstract Frailty is an emerging geriatric syndrome characterized by higher vulnerability to stressors, with ...
  https://medworm.com/journal/ageing-research-reviews/
*  Joseph Paruta - Wikipedia
It is suspected that Joseph suffered from Werner syndrome, a rare autosomal recessive disorder that is characterized by the ... By middle age he started to lose his telltale white hair as the Werner's syndrome worsened. He had a hoarse voice and his skin ... It is also suspected that he suffered from impulse control disorders such as antisocial personality disorder. Gravano would ... By 1959, at the age of thirty Joseph had the telltale condition of the syndrome by having a "birdlike" facial appearance. This ...
  https://en.wikipedia.org/wiki/Joseph_Paruta
*  WRN - ddPCR Probe - Digital PCR | PrimePCR | Bio-Rad
Defects in this gene are the cause of Werner syndrome an autosomal recessive disorder characterized by premature aging. [ ...
  http://www.bio-rad.com/en-us/prime-pcr-assays/assay/dhsacpe5039819-primepcr-ddpcr-expression-probe-assay-wrn-human
*  CP-91149 | High-Throughput Screen for the Chemical Inhibitors
Germline mutations in the WRN gene cause an autosomal recessive disorder Werner syndrome (WS). WS is usually characterized by ... We record that the manifestation of Werner proteins facilitates the changeover in human being cells of ALT type I love ... role from the SV40 source of replication and the consequences of Werner proteins and telomerase on telomere framework and ... Werner protein also colocalizes with telomeres in human ALT cells [13]. cells that lack functional telomerase undergo telomere ...
  http://acancerjourney.info/index.php/tag/cp-91149/
*  'werner syndrome' Protocols and Video...
... werner syndrome' include 'A Fluorescence-based Exonuclease Assay to Characterize DmWRNexo, Orthologue of Human Progeroid WRN ... Werner Syndrome: An autosomal recessive disorder that causes premature aging in adults, characterized by sclerodermal skin ...
  https://www.jove.com/keyword/werner+syndrome
*  Werner's syndrome protein (WRN) migrates Holliday junctions and co‐localizes with RPA upon replication arrest | EMBO Reports
Individuals affected by the autosomal recessive disorder Werner's syndrome (WS) develop many of the symptoms characteristic of ... Fry, M. and Loeb, L.A. (1999) Human Werner syndrome DNA helicase unwinds tetrahelical structures of the fragile X syndrome ... Yamagata, K., Kato, J., Shimamoto, A., Goto, M., Furuichi, Y. and Ikeda, H. (1998) Bloom's and Werner's syndrome genes suppress ... Kamath‐Loeb, A.S., Shen, J.C., Loeb, L.A. and Fry, M. (1998) Werner syndrome protein: II. Characterization of the integral 3′-5 ...
  http://embor.embopress.org/content/1/1/80
*  Lipodystrophy, including Lipoatrophy
Psychiatry healthcare professionals gain a thorough knowledge base of psychiatric disorder information to offer the best ... Werner syndrome: Autosomal recessive disorder, prematurely aged appearance, cataract, diabetes mellitus, hypogonadism, ... Leprachaunism (Donohue syndrome): Rare autosomal recessive disorder, mutations in the insulin receptor gene, intrauterine and ... Cockayne syndrome: Rare auotosomal recessive disorder characterized by growth failure, onset during second year of life, ...
  http://www.psychiatryadvisor.com/dermatology/lipodystrophy-including-lipoatrophy/article/589225/
*  Werner syndrome
... is a rare autosomal recessive disorder, caused by mutations in the WRN gene. Clinical findings include: senile ... Werner syndrome (WS) is an autosomal recessive genetic instability and progeroid ('premature aging') syndrome which is ... Unfortunately there is no cure for Werner syndrome at this time. If you or a loved one has been diagnosed with Werner syndrome ... "Werner syndrome" (open studies are recruiting volunteers) and 1 "Werner syndrome" studies with "all" status. Visit ...
  http://www.diseaseinfosearch.org/result/7471
*  Atypical Werner syndrome | definition of Atypical Werner syndrome by Medical dictionary
What is Atypical Werner syndrome? Meaning of Atypical Werner syndrome medical term. What does Atypical Werner syndrome mean? ... Looking for online definition of Atypical Werner syndrome in the Medical Dictionary? Atypical Werner syndrome explanation free ... Werner syndrome. (vĕr′nər) or Werner's syndrome. (-nərz). n.. An autosomal recessive disorder characterized by short stature ... Werner syndrome. (redirected from Atypical Werner syndrome). Also found in: Dictionary. Wer·ner syn·drome. (wĕr'nĕr), [MIM* ...
  https://medical-dictionary.thefreedictionary.com/Atypical+Werner+syndrome
*  Werner syndrome - Wikipedia
Werner syndrome (WS), also known as "adult progeria", is a rare, autosomal recessive disorder which is characterized by the ... Werner syndrome is named after the German scientist Otto Werner. He identified the syndrome in four siblings observed with ... The mutation in the WRN gene that causes Werner syndrome is autosomal and recessive, meaning that sufferers must inherit a copy ... Otto Werner was the first to observe Werner syndrome in 1904 as a part of his dissertation research. As a German ...
  https://en.wikipedia.org/wiki/Werner_syndrome
*  WRNIP1 - PrimePCR Assay and Template | Life Science | Bio-Rad
Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. The protein encoded by this ... Werner helicase interacting protein 1 Assay Type: SYBR® Green Assay Design: Exonic Application: Gene Expression Unique Assay ID ... Werner helicase interacting protein 1 Assay Type: SYBR® Green Assay Design: exonic Application: Gene Expression Unique Assay ID ... Werner helicase interacting protein 1 Assay Type: Probe Assay Design: exonic Application: Gene Expression Unique Assay ID: ...
  http://www.bio-rad.com/en-us/prime-pcr-assays/gene/wrnip1-human
*  To Compare Corneal Aberration in Subjects With Contralateral AcrySof IQ Toric Intraocular Lens (IOL) and AcrySof IQ IOL With...
Werner Syndrome. An autosomal recessive disorder that causes premature aging in adults, characterized by sclerodermal skin ... Rothmund-thomson Syndrome. An autosomal recessive syndrome occurring principally in females, characterized by the presence of ... Hallermann's Syndrome. An oculomandibulofacial syndrome principally characterized by dyscephaly (usually brachycephaly), parrot ... numerous pathogenic variants in additional genes associated with autosomal-recessive inf.... Grade of Cataract and Its ...
  https://www.bioportfolio.com/resources/trial/69137/To-Compare-Corneal-Aberration-in-Subjects-With-Contralateral-AcrySof-IQ-Toric-Intraocular.html
*  High-deductible Health Plan Enrollment Among Adults Aged 18-64 With Employment-based Insurance Coverage.
Werner Syndrome. An autosomal recessive disorder that causes premature aging in adults, characterized by sclerodermal skin ... High Deductible Health Plans and Bipolar Disorder. Using eleven years (2004-2014) of claims data from the largest US commercial ...
  https://www.bioportfolio.com/resources/pmarticle/2140968/High-deductible-Health-Plan-Enrollment-Among-Adults-Aged-18-64-With-Employment.html
*  Understanding the impact of 1q21.1 copy number variant | Orphanet Journal of Rare Diseases | Full Text
... an autosomal recessive disorder, associated with predisposition to cancer and premature aging, neither of which were noted in ... The Werner syndrome LBCs (WRN) were from a WRN syndrome patient homozygous for the p.Arg368X pathogenic mutation. A549 ... Franchitto A, Oshima J, Pichierri P: The G2-phase decatenation checkpoint is defective in Werner syndrome cells. Cancer ... Copy Number VariantAtaxia Telangiectasia MutateAMPK ActivityCopy Number ChangeWerner Syndrome ...
  https://ojrd.biomedcentral.com/articles/10.1186/1750-1172-6-54
*  Werner Syndrome - GeneReviews® - NCBI Bookshelf
Individuals with Werner syndrome develop normally until the end of the first decade. The first sign is the lack of a growth ... Myocardial infarction and cancer are the most common causes of death; the mean age of death in individuals with Werner syndrome ... Werner syndrome is characterized by the premature appearance of features associated with normal aging and cancer predisposition ... an autosomal recessive disorder caused by pathogenic variants in RECQL4) and Bloom syndrome (an autosomal recessive disorder ...
  https://www.ncbi.nlm.nih.gov/books/NBK1514/
*  Absence of premature senescence in Werner's syndrome keratinocytes
Werner's syndrome (WS) is an autosomal recessive genetic disorder caused by loss of function mutation in wrn and is a useful ... This is in support that Werner's syndrome is a segmental progeroid syndrome. ... Ibrahim B, Sheerin AN, Jennert-Burston K et al (2016) Absence of premature senescence in Werner's syndrome keratinocytes. ...
  https://bradscholars.brad.ac.uk/handle/10454/10330