*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
OHCs are cylindrical sensorimotor cells located in the Organ of Corti, the auditory organ inside the mammalian inner ear. The ... and the hair cells of the utricle are similar in both structure and function to the hair cells in the auditory organ, the organ ... Neuroscience, Issue 36, hearing, mice, cochlea, organ of Corti, organotypic, culture, hair cell, stem cell, gene expression, in ... Since there is no cell line that satisfactorily represents mammalian hair cells, research on hair cells relies on primary organ ...
  https://www.jove.com/visualize/abstract/24804771/a-lack-immune-system-genes-causes-loss-high-frequency-hearing-but
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
OHCs are cylindrical sensorimotor cells located in the Organ of Corti, the auditory organ inside the mammalian inner ear. The ... Combined fMRI and TMS applied over the auditory cortex should enable a better understanding of brain mechanisms of auditory ... We will use somatosensory stimuli to locate the hand somatosensory areas, auditory stimuli to locate the auditory cortices, ... Auditory cortex pertains to the processing of sound, which is at the basis of speech or music-related processing1. However, ...
  https://www.jove.com/visualize/abstract/19890383/effect-before-cause-supramodal-recalibration-of-sensorimotor-timing
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
OHCs are cylindrical sensorimotor cells located in the Organ of Corti, the auditory organ inside the mammalian inner ear. The ... and the hair cells of the utricle are similar in both structure and function to the hair cells in the auditory organ, the organ ... Since there is no cell line that satisfactorily represents mammalian hair cells, research on hair cells relies on primary organ ... rows of outer hair cells that span the length of the organ of Corti. Hair cells transduce sound-induced mechanical vibrations ...
  https://www.jove.com/visualize/abstract/23284995/neurotrophin-gene-therapy-for-sustained-neural-preservation-after
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
OHCs are cylindrical sensorimotor cells located in the Organ of Corti, the auditory organ inside the mammalian inner ear. The ... Bioengineering, Issue 86, Label-free optics, quantitative microscopy, cellular biophysics, cell mass, cell volume, cell density ... reconstruction facilitates the study of 3D shape and volume change of an organ at the level of macrostructures made up of cells ... We here describe the use of PAFP and PSFP expression to image two protein species in fixed cells. Extension of the technique to ...
  https://www.jove.com/visualize/abstract/25360586/convolutional-virtual-electric-field-for-image-segmentation-using
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... while auditory hair cells in the organ of Corti are the primary transducers for hearing 1. Cell fate specification in these ... Auditory hair cells located within the mouse organ of Corti detect and transmit sound information to the central nervous system ... Neuroscience, Issue 36, hearing, mice, cochlea, organ of Corti, organotypic, culture, hair cell, stem cell, gene expression, in ... rows of outer hair cells that span the length of the organ of Corti. Hair cells transduce sound-induced mechanical vibrations ...
  https://www.jove.com/visualize/abstract/25706271/integrated-annotation-analysis-situ-hybridization-images-using-imanno
*  Ear tipping | Article about ear tipping by The Free Dictionary
organ of hearing and equilibrium. The human ear consists of outer, middle, and inner parts. The outer ear is the visible ... The organ of Corti contains several cell types in addition to the auditory hair cells. The hair cells lying on the internal ... The alternating changes of pressure agitate the basilar membrane on which the organ of Corti rests, moving the hair cells. This ... Each of the otolith organs also has a sensory area, called a macula, that contains hair cells and supporting cells. The cilia ...
  http://encyclopedia2.thefreedictionary.com/ear+tipping
*  The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation...
The auditory hair cells in the organ of Corti located in the cochlea also fall into two categories, inner hair cells and outer ... The hair cells and support cells of the organ of Corti continue to disappear until the entire organ of Corti has been destroyed ... Ultrastructural analysis of the organ of Corti. To determine the ultrastructural defects in the cells of the organ of Corti, we ... Similarly, the organization of the auditory hair cells in the organ of Corti is also aberrant. The characteristic three rows of ...
  http://dev.biologists.org/content/130/1/221
*  Glossary :: Sound Transduction
Inner hair cell. A type of auditory cell in the organs of Corti; the primary transducer of sound into change in membrane ... An auditory receptor organ which contains rods of Corti, hair cells, and supporting cells.. ... A type of auditory receptor cell in the organ of Corti within the inner ear.. ... Hair cell. An auditory cell that transduces sound energy into a change in membrane potential, or a vestibular cell that ...
  https://mda06kf.webnode.com/glossary/
*  Defining the cellular environment in the organ of Corti following extensive hair cell loss: a basis for future sensory cell...
... the sensory epithelium repairs to close the lesions but no new hair cells arise and hearing impairment ensues. For any cell ... Following the loss of hair cells from the mammalian cochlea, ... cells from the organ of Corti - the auditory sensory epithelium ... GLAST expression increases over the latter stages of organ of Corti development [32]. Supporting cells of the organ of Corti ... In the CBA/Ca mice, the repaired organ of Corti formed of expanded Deiters' cells persisted along the entire organ of Corti ...
  http://www.biomedsearch.com/nih/Defining-Cellular-Environment-in-Organ/22299045.html
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
OHCs are cylindrical sensorimotor cells located in the Organ of Corti, the auditory organ inside the mammalian inner ear. The ... quantification of cell behavior in a confluent layer, with regard to barrier function, cell motility, quality of cell-cell and ... is an in vitro impedance measuring system to quantify the behavior of cells within adherent cell layers. To this end, cells are ... In order to evaluate whether co-localization of two cell types is the mere result of random cell positioning or reflects ...
  https://www.jove.com/visualize/abstract/25923338/passive-acoustic-monitoring-temporal-variability-odontocete-tonal
*  Neurog1 can partially substitute for Atoh1 function in hair cell differentiation and maintenance during organ of Corti...
... mechanotransducers that convert sound into auditory signals in the mammalian organ of Corti (OC). Previous work demonstrated ... The organ of Corti (OC) is such a model system, with hair cells (HCs) and supporting cells (SCs) organized into the most ... 2014). Inner ear hair cell-like cells from human embryonic stem cells. Stem Cells Dev. 23, 1275-1284. doi:10.1089/scd.2014.0033 ... Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti. Dev. Cell ...
  http://dev.biologists.org/content/142/16/2810
*  Regulated vesicular trafficking of specific PCDH15 and VLGR1 variants in auditory hair cells.
Auditory / metabolism, ultrastructure*. Immunoprecipitation. Mice. Mice, Neurologic Mutants. Mutation. Organ of Corti / ... Cell Compartmentation. Cell Differentiation. Cell Polarity / physiology*. Disease Models, Animal. Gene Knockdown Techniques. ... coimmunoprecipitation experiments between SNAP25 and VLGR1 show a physical interaction of these two proteins in organ of Corti ... Immature mouse cochleae and UB/OC-1 cells were used in this work to address whether specific variants of PCDH15 and VLGR1 are ...
  http://www.biomedsearch.com/nih/Regulated-Vesicular-Trafficking-Specific-PCDH15/23035094.html
*  Frontiers | Assessing Auditory Processing Deficits in Tinnitus and Hearing Impaired Patients with the Auditory Behavior...
Since HL, tinnitus and APD affects to several parts of the ascending auditory pathway from the periphery to the auditory cortex ... Since HL, tinnitus and APD affects to several parts of the ascending auditory pathway from the periphery to the auditory cortex ... These auditory impairments can be concomitant or mutually excluding. APD are not necessarily accompanied by significant HL, ... These auditory impairments can be concomitant or mutually excluding. APD are not necessarily accompanied by significant HL, ...
  https://www.frontiersin.org/articles/10.3389/fnins.2017.00187/full
*  Canal | definition of canal by Medical dictionary
... containing the auditory receptor cells (the organ of Corti), is sandwiched between the scala vestibuli above and the scala ... Either the external auditory canal or the internal auditory canal. See: external auditory canal ; internal auditory canal birth ... canal of Corti. See: Corti craniopharyngeal canal In the embryo, a temporary tubular space in the cartilage of the base of the ... canal of Corti a space between the outer and inner rods of Corti. ... canal of Corti. a space between the outer and inner rods of ...
  https://medical-dictionary.thefreedictionary.com/canal
*  Volkmann canals | definition of Volkmann canals by Medical dictionary
... containing the auditory receptor cells (the organ of Corti), is sandwiched between the scala vestibuli above and the scala ... Either the external auditory canal or the internal auditory canal. See: external auditory canal ; internal auditory canal birth ... canal of Corti. See: Corti craniopharyngeal canal In the embryo, a temporary tubular space in the cartilage of the base of the ... See: external auditory meatus. facial canal The tunnel followed by the facial nerve through the temporal bone. Inside the skull ...
  http://medical-dictionary.thefreedictionary.com/Volkmann+canals
*  Hearing - Wikipedia
... specialized auditory receptors located within the organ of Corti. While the hair cells do not produce action potentials ... It is divided lengthwise by the organ of Corti, which is the main organ of mechanical to neural transduction. Inside the organ ... 2011). "Integrating the biophysical and molecular mechanisms of auditory hair cell mechanotransduction". Nat Commun. 2: 523. ... 2011). "Integrating the biophysical and molecular mechanisms of auditory hair cell mechanotransduction". Nat Commun. 2: 523. ...
  https://en.wikipedia.org/wiki/Hearing
*  Trophic Support of Cultured Spiral Ganglion Neurons by Depolarization Exceeds and Is Additive with that by Neurotrophins or...
... a central axon projects to the cochlear nucleus and a peripheral axon to the organ of Corti. Hair cells, the auditory receptors ... 1994) Expression of BDNF and NT-3 mRNA in hair cells of the organ of Corti: quantitative analysis in developing rats. Hear Res ... In mature organ of Corti, NT-3 is expressed in the inner hair cells, and BDNF is not expressed (Ylikoski et al., 1993; Pirvola ... SGN appearance was examined in cells cultured under the same conditions as used for the cell counts described above; the cells ...
  http://www.jneurosci.org/content/17/6/1959.long
*  Postgangionic | definition of Postgangionic by Medical dictionary
These ganglia contain the cell bodies of the neurons that receive auditory signals from the organ of Corti. The axons of these ... It consists of bipolar cells that send fibers peripherally to the organ of Corti and centrally to the cochlear nuclei of the ... Besides neuronal cell bodies, these ganglia contain satellite cells, Schwann cells, axonal processes, and blood vessels. The ... sending fibers peripherally to the organ of Corti and centrally to the cochlear nuclei of the brainstem. Called also Corti's ...
  http://medical-dictionary.thefreedictionary.com/Postgangionic
*  Susan K. McConnell's Profile | Stanford Profiles
The mammalian auditory sensory epithelium, the organ of Corti, comprises the hair cells and supporting cells that are pivotal ... When crude cell contacts were restored by pelleting E29 cells together, most transplanted neurons cells became specified to ... reduction in the number of auditory hair cells. The primary cause appears to be reduced precursor cell proliferation in the ... to inductions and cell-cell interactions that determine cell fates more flexibly. ...
  https://profiles.stanford.edu/susan-mcconnell
*  Molecular remodeling of tip links underlies mechanosensory regeneration in auditory hair cells. - PubMed - NCBI
... in the IHCs of the mouse organ of Corti dissected at P1 (top) and P6 (bottom). For each age, left insets show representative ... Molecular remodeling of tip links underlies mechanosensory regeneration in auditory hair cells.. Indzhykulian AA1, Stepanyan R ... In terminally differentiated mammalian auditory hair cells, tip links are subjected to sound-induced forces throughout an ... Molecular Remodeling of Tip Links Underlies Mechanosensory Regeneration in Auditory Hair Cells ...
  https://www.ncbi.nlm.nih.gov/pubmed/23776407
*  Frontiers | Potassium Channel Activator Attenuates Salicylate-Induced Cochlear Hearing Loss Potentially Ameliorating Tinnitus |...
Salicylate-induced hearing loss is believed to arise from a reduction in the electromotile response of outer hair cells (OHCs) ... Salicylate-induced hearing loss is believed to arise from a reduction in the electromotile response of outer hair cells (OHCs) ... KCNQ2 is expressed in the modiolus and organ of corti, synaptic regions under hair cells, spiral ganglion auditory neurons, and ... KCNQ4, a novel potassium channel expressed in sensory outer hair cells, is mutated in dominant deafness. Cell (1999) 96:437-46 ...
  https://www.frontiersin.org/articles/10.3389/fneur.2015.00077/full
*  Anatomy Atlases: Atlas of Microscopic Anatomy: Section 1 - Cells
Bipolar cell bodies: Spiral ganglion. Peripheral processes of sensory hair cells located in the organ of Corti.* Central ... auditory part of the eighth cranial nerve). See Plate 311. *Corti was a nineteenth-century Italian anatomist. Next Page , ... SPIRAL GANGLION CELLS. Cochlear nerve Guinea pig, Müller's fluid, H. & E., 612 x.. Bone: Modiolus or central conical pillar of ... Plate 6.105 Spiral Ganglion Cells: Cochlear nerve. Ronald A. Bergman, Ph.D., Adel K. Afifi, M.D., Paul M. Heidger, Jr., Ph.D.. ...
  http://www.anatomyatlases.org/MicroscopicAnatomy/Section06/Plate06105.shtml
*  Deafness | definition of deafness by Medical dictionary
n impaired hearing caused by pathologic conditions in the auditory nerve or the hair cells of the organ of Corti in the inner ... Alexander's deafness congenital deafness due to cochlear aplasia, chiefly of the organ of Corti and adjacent ganglion cells, ... damage to the organ of Corti by noise; or a tumor of an auditory nerve). Hearing aids are usually of little benefit. ... Mondini's deafness congenital deafness due to dysgenesis of the organ of Corti, with partial aplasia of the bony and membranous ...
  https://medical-dictionary.thefreedictionary.com/deafness
*  Auditory fatigue - Wikipedia
The remainder of this article mainly references the cochlea, outer hair cells, and organ of Corti. In general, structural ... The OHCs are the most fragile of the hair cells, hence their involvement in auditory fatigue and other hearing impairments. ... The outer hair cells, or OHCs, can be thought of as microamplifiers that provide stimulation to the inner hair cells. ... Auditory fatigue is defined as a temporary loss of hearing after exposure to sound. This results in a temporary shift of the ...
  https://en.wikipedia.org/wiki/Auditory_fatigue