Martineau, C; Najyb, O; Signor, C; Rassart, É; Moreau, R (September 2016). "Apolipoprotein D deficiency is associated to high ... "Structural insight into the dual ligand specificity and mode of high density lipoprotein association of apolipoprotein D". The ... Identification of apolipoprotein D, apolipoprotein A-IV, apolipoprotein E, and apolipoprotein A-I". The Journal of Biological ... Apolipoprotein D (ApoD) is a component of HDL that has no marked similarity to other apolipoprotein sequences. It has a high ...

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.. 85. ... BIRC7-E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer.. 133. ... Crystal structure of UbcH5b~ubiquitin intermediate: insight into the formation of the self-assembled E2~Ub conjugates.. 46. ... Systematic E2 screening reveals a UBE2D-RNF138-CtIP axis promoting DNA repair.. 35. ...

Apolipoprotein E. The gene regulating the apolipoprotein E is considered a significant risk factor in the presence of AD in ... A similar association has been reported in persons with DS and dementia. [95] Telomere shortening may be a biological marker of ... In patients without DS, the APOE ϵ four alleles are associated with an increased risk of AD, and the ϵ e2 allele may be ... Associations of vegetable and fruit consumption with age-related cognitive change. Neurology. 2006 Oct 24. 67(8):1370-6. [QxMD ...

Protective role of the apolipoprotein E2 allele in age-related disease traits and survival: evidence from the Long Life Family ... Genome-wide association study of personality traits in the long life family study.. Bae HT, Sebastiani P, Sun JX, Andersen SL, ... Genome-Wide Association Study and Linkage Analysis of the Healthy Aging Index.. Minster RL, Sanders JL, Singh J, Kammerer CM, ... Independent associations of TOMM40 and APOE variants with body mass index.. Kulminski AM, Loika Y, Culminskaya I, Huang J, ...

Apolipoprotein E4 Medicine & Life Sciences 44% * Apolipoprotein E2 Medicine & Life Sciences 29% ... Association of Apolipoprotein e with Intracerebral Hemorrhage Risk by Race/Ethnicity: A Meta-analysis. JAMA neurology. 2019 Apr ... Association of Apolipoprotein e with Intracerebral Hemorrhage Risk by Race/Ethnicity : A Meta-analysis. In: JAMA neurology. ... Association of Apolipoprotein e with Intracerebral Hemorrhage Risk by Race/Ethnicity: A Meta-analysis. / Marini, Sandro; ...

Apolipoprotein E (APOE) is a lipid-transport protein abundantly expressed in most neurons in the central nervous system. APOE- ... Role of apolipoprotein E in neurodegenerative diseases Vo Van Giau,1 Eva Bagyinszky,1 Seong Soo A An,1 SangYun Kim2 1Department ... four different mutations give a band at the E2 position, E2 (Arg158 → Cys), E2 (Lys146 → Gln), E2 (Arg145 Cys), and E2- ... Identification and characterization of a novel apolipoprotein E variant, apolipoprotein E3′ (Arg136 → His): association with ...

Association of Apolipoprotein e2 Allele with Insulin Resistance and Risk of Type 2 Diabetes Mellitus Among an Admixed ... Association between vitamin A, vitamin E and apolipoprotein E status with mild cognitive impairment among elderly people in low ... Apolipoprotein E4 association with metabolic syndrome depends on body fatness. Atherosclerosis 2015 Dec 245 35-42. Torres-Perez ... Association between Apolipoprotein E Variants and Obesity-Related Traits in Mexican School Children. Journal of nutrigenetics ...

Results: The ε4 allele grouping (E2 = 2/2,2/3,2/4; E3 = 3/3; E4 = 3/4,4/4) was associated with a smaller increase in ... Dive into the research topics of Preliminary report on the association of apolipoprotein E polymorphisms, with postoperative ... title = "Preliminary report on the association of apolipoprotein E polymorphisms, with postoperative peak serum creatinine ... T1 - Preliminary report on the association of apolipoprotein E polymorphisms, with postoperative peak serum creatinine ...

Results: ApoE e2 was over-represented in 251 perinatal deaths (13% v 8% in healthy newborns, odds ratio (OR) = 1.63, 95% ... Little is known of the distribution of ApoE alleles in newborns, and their association with perinatal brain damage has not been ... Background: The apolipoprotein E (ApoE) polymorphism has been well studied in the adult human population, in part because the ... The raised prevalence of ApoE e2 associated with perinatal death suggests that this allele is detrimental to pregnancy outcome ...

The results presented demonstrate that the association between ApoE gene and CVD may be modulated by the presence of MetS, with ... Apolipoprotein E (ApoE) is involved on cholesterol and triglycerides metabolism regulation. Once ApoE polymorphism may ... Among patients with MetS, we observed an independent association between CVD prevalence and E4 allele frequency (OR 2.42 (1.17 ... These associations remained significant even after confounding factor corrections. ...

Apolipoprotein E moderates the association between non‐APOE polygenic risk score for Alzheimers disease and aging on ... Apolipoprotein E moderates the association between non‐APOE polygenic risk score for Alzheimers disease and aging on ... APOE ε4 can modify the association between polygenic risk scores (PRSs) and longitudinal cognition decline, with the modifying ... APOE ε4 can modify the association between PRS and cognition decline.. Highlights ...

No association was found between K1 intake and prostate cancer. As noted above, 5, 6 cheese, which provides the longer-chain ... Apolipoprotein E polymorphism: A new genetic marker of hip fracture risk-The Study of Osteoporotic Fractures.. . J Bone Miner ... Thus ApoE genotype significantly impacts blood levels of vitamin K, which are highest in E2, intermediate in E3 and lowest in ... Association of congenital deficiency of multiple vitamin K-dependent coagulation factors and the phenotype of the warfarin ...

É 4 status. We used cerebrospinal fluid (CSF) amyloid-ß (Aß)42 and phosphorylated tau (p-tau) to investigate associations with ... The brain-derived neurotropic growth factor (BDNF) gene has been linked to dementia, inflammation, and Apolipoprotein E (APOE) ... Association Between Cognition, Health Related Quality of Life, and Costs in a Population at Risk for Cognitive Decline. ... BACKGROUND: The association between health-related quality of life (HRQoL) and care costs in people at risk for cognitive ...

A08: Association Between Food Opportunities During the School Day and Selected Dietary Behaviors of Alternative High School ... M. Tjepkema, R. Wilkins, S. Senécal, É. Guimond, C. Penney. (Includes podcast with M. Tjepkema, Senior Research Analyst at ... A05: Cardiovascular Risk According to Plasma Apolipoprotein and Lipid Profiles in a Canadian First Nation ...

Apolipoprotein E2 transgenic rabbits. Modulation of the type III hyperlipoproteinemic phenotype by estrogen and occurrence of ... American Diabetes Association, American Heart Association, American Society for Clinical Nutrition, and Endocrine Society ... American Diabetes Association, American Federation for Medical Research, American Medical Association, American Society of ... The association of triglyceride levels with the incidence of initial and recurrent acute pancreatitis. Lipids Health Dis. 2021 ...

Recent studies show an association between elevated plasma LDL, a well-known cardiovascular risk factor, and a higher risk of ... Association of Apolipoprotein E in Lipoprotein subspecies with risk of dementia. JAMA Netw Open. 2020;3(7): e209250. ... 2018;12(1):89-98.e2.. Article PubMed Google Scholar *. Koch M, DeKosky ST, Goodman M, Sun J, Furtado JD, Fitzpatrick AL, et al ... Association of plasma apolipoproteins and levels of inflammation-related factors with different stages of Alzheimers disease: ...

A similar association has been seen with bacterial infections in numerous studies. A meta-analysis of 25 separate studies, ... There was no correlation between carriers and noncarriers of apolipoprotein E (ApoE) allele and baseline periodontitis or ... He served as president to the Colorado Association of Naturopathic Physicians and is a past member of the board of directors of ... To observe any associations between periodontitis and dementia severity, rate of cognitive decline, or chronic inflammation in ...

APOE2/E2 and APOE2/E3 carriers vs. others) did not show an association with T2DM (OR [95% CI] = 0.88 [0.71-1.08). The ... Retinopathy; T2DM; Apolipoprotein E; Polymorphism; Gender Popis. Background Common polymorphisms within the apolipoprotein E ( ... We perform the case-control study to analyse the association between the APOE polymorphism and risk of T2DM and to analysed the ... Yet, APOE4 allele revealed an association with retinopathy. In particular, female T2DM patients with at least one APOE4 allele ...

Apolipoprotein E e2 genotype delays onset of dementia with Lewy bodies in a Norwegian cohort. Journal of neurology, ... Association of tumor necrosis factor-alpha 308G/A polymorphism with recurrent miscarriages in women. Journal of human ... Association between inherited CYP2D6/2C19 phenotypes and anticholinergic measures in elderly patients using anticholinergic ...

Given no major result of this core mutation on association of viral glycoprotein E2 and core proteins, this unexplored pathway ... Interestingly, parts within the particularly low density lipoprotein this kind of as apolipoprotein B and apolipoprotein E are ... Colocalization concerning Apoli poprotein B and core was also not affected by 79A82A core mutation. It is plausible that ... may possibly involve occasions relevant with viral particle secretory pathway af ter powerful assembly of viral glycoprotein E2 ...

Apolipoprotein ε in Brain and Retinal Neurodegenerative Diseases.. Morteza Abyadeh, Vivek Gupta, Joao A Paulo, Samran Sheriff, ... Associations between the gut-microbiome and PD symptoms, and between lifestyle factors (fibre intake, physical activity, and ... likewise ApoE E2 allele, which is a protective factor for AD, has been implicated as a risk factor for AMD and glaucoma. This ... The E4 allele of Apolipoprotein E (APOE) is a well-established genetic risk factor for late onset AD. The ApoE ε4 allele is ...

Effect of Replacing Race With Apolipoprotein L1 Genotype in Calculation of Kidney Donor Risk Index Journal Club. April 21, 2017 ... The American Association of Immunologists 2012 Summer Immunology Courses. July 29 - August 3, 2012 ... 7th Biennial Congress of the Asian-Pacific Hepato-Pancreato-Biliary Association (A-PHPBA 2019). September 4 - 7, 2019 ... Emirates Medical Association- Nephrology and Transplantation Society Conference 2022. December 9 - 12, 2022 ...

Association of the length of oestrogen exposure with risk of incident stroke in postmenopausal women: Insights from a 20-year ... Effects of gender, age and menopausal status on serum apolipoprotein concentrations. PMID: 27086565 ... É, Wong LK; TIAregistry.org Investigators.N Engl J Med. 2016 Apr 21;374(16):1533-1542. ... Unraveling the associations of age and menopause with cardiovascular risk factors in a large population-based study. PMID: ...

Every person has an APOE genotype determined by pairs of these alleles: APOE3/E3 (the most common), APOE3/E4, APOE3/E2, APOE2/ ... APOE encodes a secreted apolipoprotein involved in lipid metabolism. It is best known for its three major alleles-APOE2, APOE3 ... plus four genes associated with AD through association studies or pathology (APOE, MAPT, SORL1, and TREM2). The goal is to ... E4, APOE4/E4, or APOE2/E2. Other variants , many of them rare, have also been studied. Some have been tied to AD, to other ...

RESULTS: In women with apolipoprotein E2 (phenotypes E2/2, 2/3, and 2/4) compared with women without E2 (E3/3, 4/3, and 4/4), ... We tested the association of the 15 SNPs with cholelithiasis in the discovery cohort and found a significant association (most ... CONCLUSIONS: The data suggest that apolipoprotein E2 is a genetic factor providing protection against GSD in women. In contrast ... Publication: A genome-wide association study of total bilirubin and cholelithiasis risk …. A genome-wide association study of ...

The association of hepatitis C virus glycoproteins with apolipoproteins E and B early in assembly is conserved in lipoviral ... E1/E2 heterodimer binds host apolipoproteins such as APOB and APOE thereby forming a lipo-viro-particle (LVP) (PubMed:25122793 ... The association of hepatitis C virus glycoproteins with apolipoproteins E and B early in assembly is conserved in lipoviral ... The interaction between E2 and host apolipoprotein E/APOE allows the proper assembly, maturation and infectivity of the viral ...

The protein comes in three varieties: apolipoprotein E2, E3 and E4.. People who have the gene for the E4 form of apolipoprotein ... The association between aerobic fitness and executive function is mediated by prefrontal cortex volume. Brain Behav Immun. 2012 ... The E2 gene type is slightly protective against Alzheimers disease. About 11 percent of people have one copy of it, and 0.5 ... Apolipoprotein E4 gene carriers are by no means guaranteed to be afflicted with Alzheimers disease, unlike people with the ...

B) (95 CI)22.595 1.242 0.037 0.075 (0.007?.851)0.112 0.048 0.019 1.119 (1.018?.230)APOE = apolipoprotein E; WMH = ... B) (95 CI)22.595 1.242 0.037 0.075 (0.007?.851)0.112 0.048 0.019 1.119 (1.018?.230)APOE = apolipoprotein E; WMH = white matter ... However, the majority of studies in this field have not demonstrated any Terlipressin association between APOEe4 status and WMH ... e2 and/or e3) may increase the odds of high WMH volume. This hypothesis is supported by at least two previous studies [41,42]. ...

American Medical Association, American Neuropsychiatric Association, American Psychiatric Association, and Association for ... The E3 allele, which is more common than the E2 allele, may protect tau from hyperphosphorylation, and the E2 alleles effect ... Other than the apolipoprotein E epsilon 4 (APOE E4) genotype, no polymorphisms in other genes have been consistently found to ... American Medical Writers Association, American Psychiatric Association, American Society of Addiction Medicine, Association of ...