*  Aromatase Inhibitors | Breast Cancer Action
More: What Are Aromatase Inhibitors?. In 2005, Breast Cancer Action launched an online survey to collect information from women ... Aromatase inhibitors (AIs) have quickly become standard treatments for postmenopausal women with estrogen-receptor-positive ... These reports are dedicated to the women who generously took the time to respond to BCA's Aromatase Inhibitor Side Effects ... In June 2008, BCA released the follow-up report, Side Effects Revisited: Women's Experiences with Aromatase Inhibitors based on ...
  https://bcaction.org/our-take-on-breast-cancer/treatment/aromatase-inhibitors/
*  Aromatase Inhibitor Linked to Bone Loss | Medpage Today
Taking the aromatase inhibitor exemestane (Aromasin) for primary prevention of breast cancer may weaken the bones, researchers ... Aromatase Inhibitor Linked to Bone Loss. Taking the aromatase inhibitor exemestane (Aromasin) for primary prevention of breast ... Taking the aromatase inhibitor exemestane (Aromasin) for primary prevention of breast cancer may weaken the bones, researchers ... Loss of bone density and fractures are known risks of aromatase inhibitors in breast cancer survivors taking the drugs to ...
  https://www.medpagetoday.com/hematologyoncology/breastcancer/31042
*  Improved syntheses of aromatase inhibitor... & related info | Mendeley
Another aromatase inhibitor, androst-4-ene-3,6,17-trione, has been efficiently prepared using PCC on montmorillonite K10, under ... Improved syntheses of aromatase inhibitors and neuroactive steroids efficient oxidations and reductions at key positions for ... Using testosterone as starting material, a new short synthesis of an aromatase inhibitor, 4-OHA, has been achieved through ...
  https://www.mendeley.com/papers/improved-syntheses-aromatase-inhibitors-neuroactive-steroids-efficient-oxidations-reductions-key-pos/
*  Higher Copayments Are Associated with Discontinuation of Aromatase Inhibitors
Discontinuation and nonadherence were higher among breast cancer patients taking brand name aromatase inhibitors (BAIs) vs ... Aromatase inhibitor use has been shown to reduce the risk of breast cancer recurrence. However, studies reported only 40%-60% ... Discontinuation and nonadherence were higher among breast cancer patients taking brand name aromatase inhibitors (BAIs) vs ... Discontinuation and nonadherence were higher among breast cancer patients taking brand name aromatase inhibitors (BAIs) vs ...
  http://www.prweb.com/releases/2014/10/prweb12261896.htm
*  DailyMed - Search Results for Aromatase Inhibitors
SEARCH RESULTS for: Aromatase Inhibitors [Drug Class] (65 results) * Share : JavaScript needed for Sharing tools. Bookmark & ...
  https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Aromatase%20Inhibitors&searchdb=class
*  Aromatase inhibitor - Wikipedia
Aromatase inhibitors work by inhibiting the action of the enzyme aromatase, which converts androgens into estrogens by a ... There are two types of aromatase inhibitors approved to treat breast cancer: Irreversible steroidal inhibitors, such as ... Chen S, Kao YC, Laughton CA (1997). "Binding characteristics of aromatase inhibitors and phytoestrogens to human aromatase". J ... inhibit the synthesis of estrogen via reversible competition for the aromatase enzyme. Available aromatase inhibitors (AIs) ...
  https://en.wikipedia.org/wiki/Aromatase_inhibitor
*  Smoking Seems to Make Aromatase Inhibitors Less Effective
Tags: 50 to 64, 65 and older, Estrogen-Receptor Positive, Aromatase Inhibitors, Arimidex (chemical name: anastrozole), Aromasin ... Aromatase inhibitors aren't commonly used to reduce recurrence risk in premenopausal women. Still, in some cases a ... "The treatment with aromatase inhibitors worked significantly better in the non-smoking patients," she continued. "However, we ... "Smokers who were treated with aromatase inhibitors had a three times higher risk of recurrence of breast cancer compared with ...
  https://www.breastcancer.org/research-news/smoking-may-make-ais-less-effective
*  Acupuncture Eases Joint Pain Caused by Aromatase Inhibitors
Aromatase inhibitors may cause muscle and joint aches and pains. Less common but more severe side effects of aromatase ... Both tamoxifen and aromatase inhibitors can cause side effects. Tamoxifen may cause hot flashes and increase the risk of blood ... All the women had been taking an aromatase inhibitor for at least 30 days and all had a joint pain score that was 3 or higher ... Aromatase inhibitors aren't commonly used to reduce recurrence risk in premenopausal women. ...
  https://www.breastcancer.org/research-news/acupuncture-eases-joint-pain-caused-by-ais
*  Steroidal aromatase inhibitor - Wikipedia
If nonsteroidal aromatase Inhibitors are not working or patients are relapsing, then the use of steroidal aromatase inhibitors ... Aromatase inhibitors stops this conversion and lowers the levels of estrogen. Treating breast cancer with aromatase inhibitors ... "Aromatase inhibitors: Are there differences between steroidal and nonsteroidal aromatase inhibitors and do they matter?". ... Steroidal aromatase inhibitors irreversibly inhibit the enzyme by binding covalently to the binding site of aromatase so the ...
  https://en.wikipedia.org/wiki/Steroidal_aromatase_inhibitor
*  Aromatase Inhibitors | Springer for Research & Development
... aromatase).. Whereas the first aromatase inhibitors to be used therapeutically could be shown to produce drug-induced ... However, second-generation drugs were developed and most recently third-generation inhibitors have evolved which possess ...
  https://rd.springer.com/book/10.1007/978-3-7643-8693-1
*  Preventing Sexual Dysfunction With Aromatase Inhibitors
Aromatase inhibitors (AIs) are used to try to stop breast cancer from forming or returning after treatment in women who are in ... Preventing Sexual Dysfunction in Women on Aromatase Inhibitors. Trial Phase:. Phase 2. Minimum Age:. 18 Years. Maximum Age:. N/ ... Preventing Sexual Dysfunction in Women on Aromatase Inhibitors. If you agree to take part in this study, you will be randomly ... 3. Began adjuvant therapy with an aromatase inhibitor 12 to 18 months before survey sent. out (Benchmark Survey only). 4. Was ...
  http://www.knowcancer.com/cancer-trials/NCT01603303/
*  Optimizing the Use of Aromatase Inhibitors | Cancer Network
The third-generation aromatase inhibitors (AIs)-anastrozole (Arimidex), letrozole (Femara), and exemestane (Aromasin)-are ...
  http://www.cancernetwork.com/supplements-2009-breast-cancer/optimizing-use-aromatase-inhibitors
*  Aromatase inhibitors for women with uterine fibroids | Cochrane
Aromatase inhibitors for women with uterine fibroids. Review question Are aromatase Inhibitors safe and effective for treating ... It has been suggested that aromatase inhibitors may shrink uterine fibroids by blocking the production of oestrogen. A review ... Both in vitro studies and clinical trials have suggested that use of the aromatase inhibitors (AIs), a class of anti-oestrogens ... To evaluate the effectiveness and safety of aromatase Inhibitors (AIs) in women with uterine fibroids. ...
  https://www.cochrane.org/CD009505/MENSTR_aromatase-inhibitors-for-women-with-uterine-fibroids
*  Aromatase Inhibitors: A Promising New Treatment for Endometriosis
... an aromatase inhibitor currently used to prevent breast cancer recurrence in postmenopausal women, shows promise in the ... "This study demonstrates the potential of aromatase inhibitors to significantly and rapidly reduce disease severity and pain, ... an aromatase inhibitor currently used to prevent breast cancer recurrence in postmenopausal women, shows promise in the ... We need to attack the root problem - the aromatase - in order to eliminate this cycle, halt the local production of estrogen ...
  http://www.prohealth.com/library/showarticle.cfm?libid=10264
*  Aromatase Inhibitor-Induced Erythrocytosis in a Patient Undergoing Hormonal Treatment for Breast Cancer
A. D. T. Diaz-Thomas et al., "Too much of a good thing: polycythemia and aromatase inhibitors," AAP Capital Letters, abstract ... J.-M. A. Nabholtz, "Long-term safety of aromatase inhibitors in the treatment of breast cancer," Therapeutics and Clinical Risk ... Aromatase Inhibitor-Induced Erythrocytosis in a Patient Undergoing Hormonal Treatment for Breast Cancer. Sri Lakshmi Hyndavi ... A. Iyengar and D. Sheppard, "A case of erythrocytosis in a patient treated with an aromatase inhibitor for breast cancer," Case ...
  https://www.hindawi.com/journals/crihem/2015/784783/ref/
*  Aromatase Inhibitor-Induced Erythrocytosis in a Patient Undergoing Hormonal Treatment for Breast Cancer
Aromatase Inhibitor-Induced Erythrocytosis in a Patient Undergoing Hormonal Treatment for Breast Cancer. Sri Lakshmi Hyndavi ... Aromatase inhibitors (AIs) are most commonly used for breast cancer patients with hormone receptor positive disease. Although ... We discuss the pathophysiology of aromatase inhibitor-induced erythrocytosis and reference of similar cases reported in the ... the side effect profile of aromatase inhibitors is well known, including common side effects like arthralgia, bone pain, ...
  https://www.hindawi.com/journals/crihem/2015/784783/abs/
*  BMI Affects Aromatase Inhibitor-Linked Estrogen Suppression - MPR
... positive breast cancer with either of two aromatase inhibitors, anastrozole or letrozole. ... At higher BMI, the levels of estrogen were greater for patients receiving treatment with both aromatase inhibitors, and this ... To examine the correlation between estrogen suppression and aromatase inhibitors and BMI, Elizabeth Folkerd, PhD, of the Royal ... positive breast cancer with either of two aromatase inhibitors, anastrozole or letrozole. ...
  https://www.empr.com/news/bmi-affects-aromatase-inhibitor-linked-estrogen-suppression/article/251114/
*  Acupuncture Reduces Joint Pain In Breast Cancer Patients On Aromatase Inhibitors
One of the major drawback of aromatase inhibitors, a class of drugs, commonly used in the management of estrogen receptor- ... One of the major drawback of aromatase inhibitors, a class of drugs, commonly used in the management of estrogen receptor- ... has found that acupuncture can significantly reduce the troublesome joint pain caused by the aromatase inhibitors. ...
  http://www.rttnews.com/2853620/acupuncture-reduces-joint-pain-in-breast-cancer-patients-on-aromatase-inhibitors.aspx?type=wh
*  Lack of Overall Survival Improvement Linked to Toxicity of Aromatase Inhibitors
Study says the toxicities associated with aromatase inhibitors (AIs) may explain the lack of overall survival improvement ... Lack of Overall Survival Improvement Linked to Toxicity of Aromatase Inhibitors. by Kathy Jones on August 23, 2011 at 7:54 PM ... Thus, it is conceivable that a late survival advantage with aromatase inhibitors over tamoxifen may also emerge over time." The ... The researchers write, "The cumulative toxicity of aromatase inhibitors when used as up-front treatment may explain the lack of ...
  http://www.medindia.net/news/Lack-of-Overall-Survival-Improvement-Linked-to-Toxicity-of-Aromatase-Inhibitors-89547-1.htm
*  Dimethyldiguanide Combined With Aromatase Inhibitor (AI) in Metastatic Breast Cancer - Tabular View - ClinicalTrials.gov
Dimethyldiguanide Combined With Aromatase Inhibitor (AI) in Metastatic Breast Cancer. The safety and scientific validity of ... Dimethyldiguanide Combined With Aromatase Inhibitor (AI) in Metastatic Breast Cancer. Official Title ICMJE Phase II Study of ...
  https://clinicaltrials.gov/ct2/show/record/NCT01654185
*  Aromatase inhibitors and cardiac toxicity: getting to the heart of the matter | SpringerLink
Recent advances in breast cancer treatment include the advent of aromatase inhibitors (AIs) in the adjuvant setting with better ... Venturini M, Del Mastro L (2006) Safety of adjuvant aromatase inhibitor therapy. Cancer Treat Rev 32(7):548-556PubMedCrossRef ... Pritchard KI, Abramson BL (2006) Cardiovascular health and aromatase inhibitors. Drugs 66(13):1727-1740PubMedCrossRefGoogle ... Smith IE, Dowsett M (2003) Aromatase inhibitors in breast cancer. NEJM 348(24):2432-2442CrossRefGoogle Scholar ...
  https://link.springer.com/article/10.1007%2Fs10549-006-9470-y
*  Physical Activity to Reduce Joint Pain During Aromatase Inhibitor Therapy - Full Text View - ClinicalTrials.gov
Aromatase Inhibitors. Steroid Synthesis Inhibitors. Enzyme Inhibitors. Molecular Mechanisms of Pharmacological Action. Estrogen ... Physical Activity to Reduce Joint Pain During Aromatase Inhibitor Therapy. The safety and scientific validity of this study is ... Taking an aromatase inhibitor as adjuvant treatment for State I, II, or II breast cancer for at least 4 weeks ... For post-menopausal women diagnosed with hormone-receptor positive breast cancer tumors, aromatase inhibitors (AIs) are the ...
  https://clinicaltrials.gov/ct2/show/NCT01900418?term=Leigh
*  Vaginal gene expression during treatment with aromatase inhibitors
Aromatase inhibitor-treated women had higher than expected estradiol and estrone levels but still significantly lower than ... Vaginal tissue from aromatase inhibitor-treated women had low expression of genes involved in cell differentiation, ... Background: Aromatase inhibitor (AI) treatment suppresses estrogen biosynthesis and causes genitourinary symptoms of menopause ... Vaginal gene expression during treatment with aromatase inhibitors. Kunovac Kallak, Theodora Uppsala University, Disciplinary ...
  http://uu.diva-portal.org/smash/record.jsf?pid=diva2:791163
*  Both Fish Oil and Placebo Ease Joint Pain in Women Taking Aromatase Inhibitors
Aromatase inhibitors may cause muscle and joint aches and pains. Less common but more severe side effects of aromatase ... Both tamoxifen and aromatase inhibitors can cause side effects. Tamoxifen may cause hot flashes and increase the risk of blood ... If you're currently taking an aromatase inhibitor and having joint pain, you may want to talk to your doctor about this study ... Both Fish Oil and Placebo Ease Joint Pain in Women Taking Aromatase Inhibitors * ...
  https://www.breastcancer.org/research-news/fish-oil-and-placebo-ease-joint-pain
*  A Case of Erythrocytosis in a Patient Treated with an Aromatase Inhibitor for Breast Cancer
... Abhinav Iyengar and Dawn Sheppard ... To our knowledge, erythrocytosis has not been previously described in association with aromatase inhibitors. These drugs ...
  https://www.hindawi.com/journals/crihem/2013/615189/abs/