*  Gynecomastia - Wikipedia
Testicular tumors such as Leydig cell tumors or Sertoli cell tumors (such as in Peutz-Jeghers syndrome) or hCG-secreting ... A few cases of gynecomastia caused by the rare disorders aromatase excess syndrome and Peutz-Jeghers syndrome have responded to ... Fukami, M; Miyado, M; Nagasaki, K; Shozu, M; Ogata, T (March 2014). "Aromatase excess syndrome: a rare autosomal dominant ... found to be effective in rare cases of gynecomastia from disorders such as aromatase excess syndrome or Peutz-Jeghers syndrome ...
*  Endocrinology - Reproductive Endocrinology Flashcards by Josh Davies | Brainscape
Sertoli cell, germ cell, and granulosa cell), choriocarcinomas, and adrenal tumors. Male breast cancer is an uncommon cause.. 3 ... Various syndromes, such as Kallmann syndrome, Laurence-Moon-Bardet-Biedl syndrome, and Prader-Willi syndrome are also ... Androgen excess (due to adrenal tumors, PCOS, tumors with high human choriogonadotropin, and congenital adrenal hyperplasia). ... 4) Increased activity of enzyme that catalyzes estrogen production (aromatase) that is found in obesity, hyperthyroidism, and ...
*  Sex hormone binding globulin | definition of Sex hormone binding globulin by Medical dictionary
... and increased aromatase activity contributing to relative estrogen excess.. Androgen deficiency, diabetes, and the metabolic ... Estrogen and androgen regulation of sex hormone binding globulin secretion by a human liver cell line.. Sex hormone-binding ... Late-onset hypogonadism in male patients over 60 years of age with metabolic syndrome / Altmis Yas Ustu Metabolik Sendromlu ... Conversely, diabetes and the metabolic syndrome can be risk factors for hypogonadism through some similar but mostly distinct ...
*  1P - Pathology of Male Repro Tract Flashcards - Cram.com
2) Sertoli cells respond to FSH and are support cells for maturation of spermatogonia.. 3) Also secretes inhibin, a feedback ... What is Kallman's syndrome? Migration problems of GnRH neurons from olfactory placode.. Patients have difficulty smelling.. ... Do ANDROGEN or ESTROGEN excess cause problems with testicular development? YES! Estrogen negatively feedbacks at Anterior ... Can be converted to estradiol via aromatase (c19 --, c18) What do Sertoli cells do? ...
*  Most recent papers with the keyword CYP17A1 | Read by QxMD
Leydig cell dysfunction is associated with post-transcriptional deregulation of CYP17A1 in men with Sertoli cell-only syndrome. ... Although its etiology is unknown, excess androgens are thought to be a critical factor driving the pathology of PCOS. We ... previously demonstrated that continuous exposure to the aromatase inhibitor letrozole (LET) in mice produces many hallmarks of ... cell-dysfunction-is-associated-with-post-transcriptional-deregulation-of-cyp17a1-in-men-with-sertoli-cell-only-syndrome ...
*  Androgen insensitivity syndrome - Wikipedia
"Incidental detection of Sertoli-Leydig cell tumor by FDG PET/CT imaging in a patient with androgen insensitivity syndrome". Ann ... 20 lyase deficiency 17β-hydroxysteroid dehydrogenase deficiency 5α-reductase deficiency Androgen excess in 46,XX individuals: ... 11β-hydroxylase deficiency Aromatase deficiency Glucocorticoid receptor mutations Maternal virilizing tumor (e.g. luteoma) ... and Goldberg-Maxwell syndrome; PAIS includes Reifenstein syndrome, Gilbert-Dreyfus syndrome, Lub's syndrome, "incomplete ...
*  Gynecomastia: What Causes Man Boobs
Leydig/Sertoli cell tumors, or hCG-secreting choriocarcinoma.. Tumors that arise in other glands and are involved in disturbing ... In contrast, excess consumption of foods containing estrogen-like substances known as phytoestrogens may also cause ... Gynecomastia is also a feature of Klinefelter Syndrome, a genetic disorder caused by an extra X chromosome. These individuals ... Medicine for gynecomastia includes aromatase inhibitors that include testolactone and selective estrogen receptor modulators ...
*  Congenital adrenal hyperplasia due to 21-hydroxylase deficiency - Wikipedia
2007). "Testicular adrenal rest tumors and Leydig and Sertoli cell function in boys with classical congenital adrenal ... This conversion is mediated by aromatase and can be inhibited by aromatase blockers such as testolactone. Blocking the effects ... The androgen excess is mild enough that virilization is not apparent or goes unrecognized at birth and in early childhood. ... These clinical features, of course, are those of polycystic ovary syndrome, and a small percentage of women with Polycystic ...
*  Hormones Primer - Hormone Correction
Excesses. The most common disease of GH excess is a pituitary tumor composed of somatotroph cells of the anterior pituitary. ... Estradiol is produced in the Sertoli cells of the testes. There is evidence that estradiol is to prevent apoptosis of male ... Hyperthyroidism (an example is Graves Disease) is the clinical syndrome caused by an excess of circulating free thyroxine, free ... the enzyme aromatase converts testosterone into estradiol that is responsible for masculinization of the brain in a male mice. ...
*  First Pass Miss Exam 3 Flashcards by Matthew Miller | Brainscape
Aromatase -> they can make estrogens. Both cell types make progesterone, progesterones are transferred to theca cells to become ... Androgen binding protein - used by Sertoli cells to keep T concentrations high in the lumen. Sex hormone binding globulin - ... Elevated GnRH levels due to primary gonadal failure, as in gonadal dygenesis of Turner syndrome (deletion or rearrangement of X ... Cushing's: ACTH excess - slight overproduction of aldosterone -> hypertension + hypokalemia. Addison's: ACTH deficiency - ...
*  Pesticide-Induced Diseases: Sexual and Reproductive Dysfunction - Beyond Pesticides
The Sertoli cells provide the physical and nutritional support for the spermatogenic cells. Over 400 genes were differentially ... Some common pathologies associated with aromatase disruption include breast cancer, prostate cancer, polycystic ovary syndrome ... Except for an excess of Attention Deficit Hyperactivity Disorder - ADHD (OR = 3.6, 1.3-9.6) among children born to glyphosate ... Roundup disrupts male reproductive functions by triggering calcium-mediated cell death in rat testis and Sertoli cells.. The ...
*  Endocrine/Repro Flashcards - Cram.com
LH stim theca to produce testosterone, goes to granulosa cells for aromatase to convert to 17beta estradiol (2nd stp stim by ... FSH act on Sertoli maintain spermatogenesis), also makes inhibin which inhib FSH sxn ... GH excess would do what to glucose levels glucose intolerance bc GH prevents glu uptake by cells ... the primordial germ cell arrives in the ovary at 4wk and difft into oogonia (46,2N). enter meiosis I to form 1 oocytes (46, 4N ...
*  List of syndromes - Wikipedia
... mineralocorticoid excess syndrome Arakawa's syndrome II Ardalan-Shoja-Kiuru syndrome AREDYLD syndrome Aromatase excess syndrome ... Sertoli cell-only syndrome Serum sickness-like reaction Setleis syndrome Severe acute respiratory syndrome Shaken baby syndrome ... syndrome Wende-Bauckus syndrome Werner syndrome Wernicke-Korsakoff syndrome West syndrome Westerhof syndrome Wet lung syndrome ... syndrome Levator ani syndrome Leydig cell hypoplasia Liddle's syndrome Liebenberg syndrome LIG4 syndrome Lima syndrome Limb ...
*  Free Medical Flashcards about biochem test 2 2011
Leydig cells do what?. produce testosterone from androstenedione, then send it to the sertoli cells (testicle)Stimulated by LH ... Granulosa cells=estrogens. Corpus Luteum=progesterone. These are regulated by FSH via aromatase. ... DiGeorge's syndrome is associated with a partial or complete lack of what organ?. Thymus, presents early with infections ... How is ketoacidosis conected to the high NADH from excess alcohol consumption?. (malnourished, fasted, esp) high NADH decreases ...
*  9. Reproductive System
Aromatase catalyses the conversion of testosterone to estradiol in the Sertoli cells and in other peripheral tissues. ... For example, it is believed that excess production of androgens by thecal cells will lead to follicle atresia. In addition, ... Chromosomal anomalies associated with abnormal growth include Down's syndrome, trisomy 18 and most malformation syndromes. ... That is, as the cells mature the epididymis absorbs components from the fluid including secretions from the Sertoli cells (e.g ...
*  rrr u nts 1 Flashcards - Cram.com
only sertoli cells of seminif tubules are present (germinal cell aplasia). Spermatogenesis absent. Both male and female type ... Acute syndrome, due to obstruction of cystic duct of common bile duct. Deep pain ... Acute estrinism, dec in inhibin causes inc in FSH, causing inc aromatase in Leydig and inc estrogen ... hypersecretion of gastric acid, trophic increased density of parietal cells; decrease In G cells; basic level high, no increase ...
*  Chapter 342. Disorders of the Adrenal Cortex | Harrison's Principles of Internal Medicine, 18e | AccessMedicine | McGraw-Hill...
cortisone, leading to excess activation of the MR by cortisol. Cushing's syndrome. Cortisol excess overcomes the capacity of ... autosomal dominant multiple neoplasia condition associated with cardiac myxomas, hyperlentiginosis, Sertoli's cell tumors, and ... aromatase, CYP19A1). These enzymes require electron donation via specific redox cofactor enzymes, P450 oxidoreductase (POR), ... Syndrome of apparent mineralocorticoid excess (AME). Mutations in HSD11B2 result in lack of renal activation of cortisol to ...
*  Basic Concepts
Small cell CA → Centrally located → SIADH, Eaton-Lambert, Venocaval obstruction Syndrome, Hornor's syndrome - Large Cell CA → ... Aromatase enzyme inhibitors McCune Albright syndrome has association with Cushing's syndrome, not Cushing's disease (which is ... secrete estrogen Sertoli-Leyding cell tumors - secrete testosterone Krukenberg's tumor - contains signet ring cells from ... Registered with US copy right office 20 ENDOCRINOLOGY  Hyperprolactinemia: Excess production (Pituitary adenoma) or ...
*  OB/GYN Flashcards - Cram.com
FSH (recall Sertoli cells responsible for spermatogenesis and secrete inhibin to feed back to FSH secretion). ... Polycystic ovary syndrome. Classic triad of hyperandrogenism (acne hirsutism, deep voice, clitoromegaly), anovulation (oligo- ... Aromatase inhibitors, block conversion of androgens to estrogen and treat ER+ breast cancer. ... Due to dysregulation of the menstrual cycle via excess estrogen and insufficient progesterone, occurring in adolescents just ...
*  List of OMIM disorder codes - Wikipedia
HESX1 SERKAL syndrome; 611812; WNT4 Sertoli-cell-only syndrome; 400042; ZNF148 SESAME syndrome; 612780; KCNJ10 Severe combined ... ASL Aromatase deficiency; 613546; CYP19A1 Aromatase excess syndrome; 139300; CYP19A1 Aromatic L-amino acid decarboxylase ... T cell-negative, B-cell/natural killer-cell positive; 608971; CD3D Severe combined immunodeficiency, T cell-negative, B-cell/ ... T cell-negative, B-cell/natural killer-cell positive; 608971; PTPRC Severe combined immunodeficiency, T-cell negative, B-cell/ ...
*  2014-2015 Boys Tennis Singles-Doubles Championships
Sertoli and Leydig cells were damaged. Along with structural alterations, fertility rate in experimental animals was ... CdCl2 at sub-lethal concentration strongly attenuated LH stimulated P450 aromatase activity and P450 aromatase activity and ... The thyroid gland may be define as the tissue which is capable of a accumulating iodine in great excess and combining it with ... Work at the Oceanic Institute in Hawaii has shown potential for breeding shrimp resistant to Taura syndrome virus (TSV), ...
*  Indian Patents. 258133:C-MET ANTIBODIES
USA 77:4216 (1980)); mouse sertoli cells (TM4, Mather, Biol. Reprod. 23:243-251 (1980) ); monkey kidney cells (CV1 ATCC CCL 70 ... and aromatase inhibitors that inhibit the enzyme aromatase, which regulates estrogen production in the adrenal glands, such as ... Excess, unannealed oligonucleotide was removed with a QIAQUICK PCR purification kit (Qiagen kit 28106) using a modified ... nephrotic syndrome, undesired or aberrant tissue mass growth (non-cancer), hemophilic joints, hypertrophic scars, inhibition of ...
*  How to Reverse Testicular Atrophy - 78 Steps Health Journal
... and Sertoli cell-only pheno-types (11). In addition to the loss of germ cells and atrophy, the seminiferous tubules exhibit ... But if you take in too much youll actually increase the aromatase enzyme in your body. Because Mark is a pro researcher on ... Studies on candidate syndromes (e.g., precocious puberty and macro-orchia) have yielded negative results. ... The primary factor mediating gonadal damage in acromegaly is GH excess. GH regulates testicular function, by stimulating the ...
*  Endocrinology
aromatase excess syndrome. *Androgen receptor (Androgen insensitivity syndrome). *general: Hypogonadism (Delayed puberty) ... Sutherland investigated whether hormones enter cells to evoke action, or stayed outside of cells. He studied norepinephrine, ... chemical communication between cells within a tissue or organ), autocrine signals (a chemical that acts on the same cell), and ... Some of the most common endocrine diseases include diabetes mellitus, hypothyroidism and the metabolic syndrome. Care of ...
*  11α- and 11β-Hydroxyprogesterone, Potent Inhibitors of 11β-Hydroxysteroid Dehydrogenase, Possess Hypertensinogenic Activity in...
Several important studies have led to the hypothesis that changes in 11β-HSD activity are key to the anomalous regulation of Na+ retention by glucocorticoids. The studies of Ulick et al22 23 have clearly shown that children with apparent mineralocorticoid excess syndrome have a specific defect, with markedly diminished 11β-HSD activity leading to Na+ retention, hypokalemia, and low plasma aldosterone and renin levels. When treated with cortisol, these children developed Na+ retention and a marked increase in BP, indicating that cortisol was acting as a mineralocorticoid.24 The subsequent experiments of Stewart et al8 demonstrated that the hypertension caused by excessive licorice ingestion was also due to diminished 11β-HSD activity caused by glycyrrhetinic acid inhibition of this enzyme. The earlier work of Kornel et al10 11 also indicated that impaired 11β-HSD activity may play a role in essential hypertension by showing altered ratios of ...
*  Enciklop dia
Primer reninismus: A kering sben jelenl v akt v renin f k nt a ves b l ered, a juxtaglomerularis appar tus (JGA) sejtjei termelik, proteolyticus aktiv l d st k vet en alakul ki preprorenin-, majd proreninb l. Primer reninismust okoz t pusosan a JGA-sejtek tumora, s az n. Zimmermann-pericyt kb l kifejl d haemangiopericytoma. A JGA sejtjein k v l a ves ben renint termelhetnek nephroblastoma-sejtek (Wilms-tumor), s egy b veser kok sejtjei is. Renintermel extrarenalis tumorok is ismertek, a t d , a m j, az urogenitalis traktus, az orbita s a pancreas bizonyos daganatai eset ben. L tsz lagos mineralokortikoid-t ls ly - apparent mineralocorticoid excess (AME): A gl kokortikoid hormonok mineralokortikoid aktivit s t a 11b-hidroxiszteroid-dehidrogen z (11b-HSD) enzimek szab lyozz k. Az enzimnek k t izoformja l tezik, 11b-HSD1 s 11b-HSD2. A 11b-HSD1 NADP-dependens, redukt z aktivit s enzim, melyet sz mos szerv nkben kimutattak, de AME-ben szenved betegek eset ben mut ci t nem igazoltak eddig az ...
*  Plus it
The study of human physiology is paramount to understand disease and develop rational and targeted treatments. Conversely, the study of human disease can teach us a lot about physiology. Investigations into primary inherited nephrogenic diabetes insipidus (NDI) have contributed enormously to our understanding of the mechanisms of urinary concentration and identified the vasopressin receptor AVPR2, as well as the water channel AQP2 as key players for water reabsorption in the collecting duct. Yet, there are also secondary forms of NDI, for instance as a complication of lithium treatment. The focus of this review is secondary NDI associated with inherited human diseases, such as Bartter syndrome or apparent mineralocorticoid excess. Currently, the underlying pathophysiology of this inherited secondary NDI is unclear, but there appears to be true AQP2 deficiency. To better understand the underlying mechanism(s) collaboration of clinical and experimental ...
*  Loeys-Dietz syndrome: a possible solution for Akhenaten's and his family's mystery syndrome
Several hypotheses have been proposed to explain a familial disease that caused the bizarre appearance of the royalty, including Marfan syndrome, Wilson-Turner X-linked mental retardation syndrome, Fröhlich syndrome (adiposogenital dystrophy), Klinefelter syndrome, androgen insensitivity syndrome,1 myotonic dystrophy,2 and aromatase excess syndrome in conjunction with sagittal craniosynostosis syndrome, or Antley-Bixler syndrome.3 Hawass and co-workers published results of their molecular genetic studies on mummified remains of the royal family of the 18th dynasty to determine any pathologies and familial disease that might have afflicted them.4 Tests showed no sign of craniosynostoses and Antley-Bixler or ...
*  7.3 Metabolic Alkalosis - Maintenance
Volume depletion and potassium depletion may coexist in some disorders (eg vomiting). Severe potassium depletion alone can cause a metabolic alkalosis but this is typically only of mild to moderate degree. The mechanism seems to be related to an intracellular shift of H+ ('intracellular acidosis') in exchange for K+. The alkalosis is generated predominantly due to non-renal mechanisms. Renal mechanisms are frequently involved in causing the potassium depletion (eg in syndromes of mineralocorticoid excess).. Volume depletion has long been implicated in maintenance of an alkalosis. The idea is that hypovolaemia is associated with increased fluid and sodium reabsorption in the proximal tubule and bicarbonate is reabsorbed in preference to chloride; the alkalosis thus being maintained. The role of volume depletion has probably been over-emphasised: the co-existing chloride depletion is the most important factor responsible for ...
*  Mineralocorticoids
A group of hormones (the most important being aldosterone) that regulate the balance of water and electrolytes (ions such as sodium and potassium) in the body. The mineralocorticoid hormones act on the kidney (and specifically on the tubules of…
*  Ame Restaurant - San Francisco, CA | OpenTable
Get menu, photos and location information for Ame in san francisco, CA. Or book now at one of our other 8360 great restaurants in San Francisco.
*  Diomedes Diaz - Enseñame Como Te Olvido lyrics | LyricsMode.com
Enseñame Como Te Olvido lyrics by Diomedes Diaz: Estamos frente a frente los dos / Y te confienso / Que has hecho con mi vida lo que tu
*  Çameria
Grupi Patriotik Atdhetar Çamëria eshte organ i Shoqerive Politike Atdhetare Çamëria ne Diaspore. Qellimi i ketij grupi eshte informimi, sensibilizimi dhe MOBILIZIMI i publikut shqiptar, nderkombetar dhe te huaj rreth GJENOCIDIT DHE DRAMES ÇAME dhe zgjidhjes se saj. Kjo liste organizon here pas here studime dhe debate konstruktive per zgjidhjen dhe nderkombetarizimin e çeshtjes çame. Çdo anetar eshte i lire te postoje edhe shkrime qe nuk kane lidhje me Çamërine por qellimi kryesor i kesaj liste eshte dhe mbetet çeshtja çame, islame dhe shqiptare ne Ballkan. Per te pare fotot dhe deshmite e vjetra historike te Çamerise lexuesit duhet te behen anetare te grupit. Motoja jone eshte: = | MOS PYET CFARE KA BERE CAMERIA PER TY | = = | POR THUAJ CFARE KAM BERE UNE PER CAMERINE! | =
*  Çameria
Grupi Patriotik Atdhetar Çamëria eshte organ i Shoqerive Politike Atdhetare Çamëria ne Diaspore. Qellimi i ketij grupi eshte informimi, sensibilizimi dhe MOBILIZIMI i publikut shqiptar, nderkombetar dhe te huaj rreth GJENOCIDIT DHE DRAMES ÇAME dhe zgjidhjes se saj. Kjo liste organizon here pas here studime dhe debate konstruktive per zgjidhjen dhe nderkombetarizimin e çeshtjes çame. Çdo anetar eshte i lire te postoje edhe shkrime qe nuk kane lidhje me Çamërine por qellimi kryesor i kesaj liste eshte dhe mbetet çeshtja çame, islame dhe shqiptare ne Ballkan. Per te pare fotot dhe deshmite e vjetra historike te Çamerise lexuesit duhet te behen anetare te grupit. Motoja jone eshte: = | MOS PYET CFARE KA BERE CAMERIA PER TY | = = | POR THUAJ CFARE KAM BERE UNE PER CAMERINE! | =
*  amebicide
Any agent that causes the destruction of amebas. SYN: amebacide. [ameba + L. caedo, to kill] * * * ame·bi·cide also ame·ba·cide or chiefly Brit amoe·bi·cide also amoe·ba·cide ə mē bə .sīd n a substance used to kill or capable of killing amebas…
*  Snickers Drink Sportscap 8x 350 ml - US FOOD, ihr online Shop f r ame, 15,99 €
Zutaten: MILCH (0,05% Fett) (86%), Wasser, Zucker, Fruktose, MOLKENpulver (aus MILCH), ERDNUSSpaste: ger stete ERDN SSE (1,3%), Raps l, Kakaopulver (0,6%),
*  Blog de Floo----O----oora - Floo----O----oora - Skyrock.com
*  Un-Planned Prisonhood
BILL BERKOWITZ FOR BUZZFLASH AT TRUTHOUT Rampant growth, overcrowding, neglected inmates, staffing inadequacies, and unsound facilities mark Ame...
*  Forum - Madain Sari
Hello vex and ame - recruitment is still closed for now till summer wraps up and 4.1 drops. I believe we will re-open shortly after 4.1. Thanks ...
*  人HSD3a肽(ab50442)|Abcam中国