*  Gene - Wikipedia
The nucleotide sequence of a gene's DNA specifies the amino acid sequence of a protein through the genetic code. Sets of three ... Many prokaryotic genes are organized into operons, with multiple protein-coding sequences that are transcribed as a unit. The ... "Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid" (PDF). Nature. 171 (4356): 737-8. Bibcode: ... Telomeres are long stretches of repetitive sequence that cap the ends of the linear chromosomes and prevent degradation of ...
  https://en.wikipedia.org/wiki/Gene
*  CRISPR - Wikipedia
At that time the CRISPRs were described as segments of prokaryotic DNA containing short, repetitive base sequences. In a ... Cas1 proteins have diverse amino acid sequences. However, their crystal structures are similar and all purified Cas1 proteins ... CRISPRs are found in approximately 40% of sequenced bacterial genomes and 90% of sequenced archaea. CRISPR is an abbreviation ... By manipulating the nucleotide sequence of the guide RNA, the artificial Cas9 system could be programmed to target any DNA ...
  https://en.wikipedia.org/wiki/CRISPR
*  SPdb - a signal peptide database | Springer for Research & Development
This transient, short peptide sequence functions like a... ... protein targeting and protein translocation in both prokaryotic ... The EMBL Nucleotide Sequence Database. Nucleic Acids Res 2005, 33 Database Issue: D29-33.Google Scholar ... This repetitive process can and should be eliminated by creating a centralised repository of signal peptide sequences. ... which are usually found at the amino terminus of secreted proteins. Signal peptides are present in both prokaryotic and ...
  https://rd.springer.com/article/10.1186/1471-2105-6-249
*  DNA - Wikipedia
The relationship between the nucleotide sequences of genes and the amino-acid sequences of proteins is determined by the rules ... simulation software Meiosis Mitochondrial DNA Nuclear DNA Nucleic acid double helix Nucleic acid notation Nucleic acid sequence ... of human DNA consisting of non-coding repetitive sequences. The reasons for the presence of so much noncoding DNA in eukaryotic ... Sandman K, Pereira SL, Reeve JN (December 1998). "Diversity of prokaryotic chromosomal proteins and the origin of the ...
  https://en.wikipedia.org/wiki/DNA
*  Archaea - Wikipedia
Deppenmeier, U. (2002). "The unique biochemistry of methanogenesis". Prog Nucleic Acid Res Mol Biol. Progress in Nucleic Acid ... Defenses against these viruses may involve RNA interference from repetitive DNA sequences that are related to the genes of the ... list of Prokaryotic names with Standing in Nomenclature Shotgun sequencing finds nanoorganisms - discovery of the ARMAN group ... it lacks D-amino acids and N-acetylmuramic acid. Archaea flagella operate like bacterial flagella-their long stalks are driven ...
  https://en.wikipedia.org/wiki/Archaea
*  AE BB DB Explorer
Comparative sequence analyses of amino acid residues in the active site region suggest these additional sequences have evolved ... Using inferred nucleotide sequences of ancestral organisms, we showed that the rate of nonsynonymous nucleotide substitution ... Nucleic Acids Res. 2003 Aug 1;31(15):4385-90.. The human genome contains many types of chimeric retrogenes generated through in ... Phylogenetically new insertions of repetitive sequences may contribute to genome evolution by altering the function of pre- ...
  http://antievolution.org/features/aebbexp.php?form_cmd=view_author&form_srcid=theyeti&execute=Submit
*  Publications | NEB
VISA: Visual Sequence Analysis for the comparison of multiple amino acid sequences. CABIOS. Posfai, J., Szaraz, Z., and Roberts ... Orphon spliced-leader sequences form part of a repetitive element in Angiostrongylus cantonensis. Nucl.Acids Res.. Joshua, G.W ... Nucleotide sequence of the DdeI restriction-modification system and characterization of the methylase protein. Nucl.Acids Res. ... Protein splicing removes intervening sequences in an archaea DNA polymerase. Nucl.Acids Res.. Hodges, R.A., Perler, F.B., Noren ...
  https://www.neb.com/research/publications?num=250&sorting=Year
*  Metagenomics - Wikipedia
Zhu, Wenhan; Lomsadze Alex; Borodovsky Mark (2010). "Ab initio gene identification in metagenomic sequences". Nucleic Acids ... The sequencing of the cow rumen metagenome generated 279 gigabases, or 279 billion base pairs of nucleotide sequence data, ... Misassemblies are caused by the presence of repetitive DNA sequences that make assembly especially difficult because of the ... As viruses lack a shared universal phylogenetic marker (as 16S RNA for bacteria and archaea, and 18S RNA for eukarya), the only ...
  https://en.wikipedia.org/wiki/Metagenomics
*  Frontiers | Epigenome Engineering in Cancer: Fairytale or a Realistic Path to the Clinic? | Oncology
In this regard, there is an ongoing effort to alter some amino acid sequences of the Cas9 protein in order to decrease its size ... Ishino Y, Shinagawa H, Makino K, Amemura M, Nakata A. Nucleotide sequence of the iap gene, responsible for alkaline phosphatase ... Specific targeting of cytosine methylation to DNA sequences in vivo. Nucleic Acids Res (2007) 35:740-54. doi:10.1093/nar/ ... In 1987, it was first reported that Escherichia coli K12's genome contains repetitive sequences adjacent to the alkaline ...
  https://www.frontiersin.org/articles/10.3389/fonc.2015.00022/full
*  Amino acid repeat data | Protein sequence analysis - OMICtools
Many repetitions in protein sequences can be identified by using different approaches. Several repeat families have been ... After all, the most common way to detect repeat families so far was to manually annotate the sequence family first and only ... A large portion of proteins contain repetitive motifs, which are generated by internal duplications and frequently correspond ... Amino acid repeat databases , Protein sequence analysis. A large portion of proteins contain repetitive motifs, which are ...
  https://omictools.com/amino-acid-repeat-data-category
*  Diversity and Evolution in the Genome of Clostridium difficile
Clostridium sticklandii, a specialist in amino acid degradation: revisiting its metabolism through its genome sequence. BMC ... Analysis of the nucleotide sequences of the 10-kb slpA-cwp66-secA2 cassettes from 58 genetically diverse C. difficile strains ... Nucleic Acids Res 33:616-621. doi:.10.1093/nar/gki181 [PMC free article] [PubMed] [Cross Ref] ... A comparison of homologous recombination rates in bacteria and archaea. ISME J 3:199-208. doi:.10.1038/ismej.2008.93 [PubMed] [ ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC4475645/
*  Gene - wikidoc
... or produce no change in the amino acid sequence of the protein for which they code; for example, the codons UCU and UUC both ... Prokaryotic genes are often arranged in groups called operons with promoter and operator sequences that regulate transcription ... typically encoded in a sequence of nucleotide monomers that make up a long strand of DNA, or deoxyribonucleic acid. A ... All nucleic acid synthesis in a cell occurs in the 5'-3' direction, because new monomers are added via a dehydration reaction ...
  http://www.wikidoc.org/index.php/Gene
*  Frontiers | Single-Cell (Meta-)Genomics of a Dimorphic Candidatus Thiomargarita nelsonii Reveals Genomic Plasticity |...
The dsrA group I intron also carried a MITE sequence that, like the hupL MITE family, occurs broadly across the genome. The ... Also present, are a large number of other mobile genetic elements, such as insertion sequence transposable elements and ... a manually curated genome of Bud S10 resulting from a hybrid assembly of long Pacific Biosciences and short Illumina sequencing ... a manually curated genome of Bud S10 resulting from a hybrid assembly of long Pacific Biosciences and short Illumina sequencing ...
  https://www.frontiersin.org/articles/10.3389/fmicb.2016.00603/full
*  Protocols and Video Articles Authored by Ming Chen
... causing a change in the amino acid sequence (Gly104â†'Arg). This amino acid alteration is predicted to disrupt a highly ... Their amino acid sequences are KSLRPRCWIKIKFRCKSLKF and RPRCWIKIKFRCKSLKF, respectively. One intra-molecular disulfide bridge ... PmiRKB: a Plant MicroRNA Knowledge Base Nucleic Acids Research. Jan, 2011 , Pubmed ID: 20719744 MicroRNAs (miRNAs), one type of ... monodon genome were obtained for repetitive and protein-coding sequence analyses. ...
  https://www.jove.com/author/Ming_Chen
*  Resource centre | Oxford Nanopore Technologies
VolTRAX is designed to extract nucleic acids and prepare sequencing libraries from biological samples, enabling consistent ... Short-read, high-throughput sequencing technology cannot identify the chromosomal position of repetitive insertion sequences ... Epigenetics' refers to heritable alterations of DNA that do not change the nucleotide sequence. One of the most widespread ... These genes are involved in energy transfer and amino-acid synthesis (Figs. 3b-e). ...
  https://nanoporetech.com/index.php/taxonomy/term/230
*  MCAT - Biology Flashcards by Caitlin Rodeghier | Brainscape
A series of three-nucleotide sequences on the mRNA; each corresponds to an amino acid or signifies a "start" or "stop" signal ... A base-pair substitution that changes the amino acid coding sequence of a gene to code for another amino acid. ... Cut the nucleic acids according to palindromic nucleotide sequences. Usually cuts the DNA unevenly. ... the two domains of Bacteria and Archaea are divided into several kingdoms each.. -> Archaea is more closely related to Eukarya ...
  https://www.brainscape.com/flashcards/mcat-biology-422004/packs/486133
*  Virus - Wikipedia
HIV evades the immune system by constantly changing the amino acid sequence of the proteins on the surface of the virion. This ... Mojica FJ, Díez-Villaseñor C, García-Martínez J, Soria E. Intervening sequences of regularly spaced prokaryotic repeats derive ... The type of nucleic acid is irrelevant to the shape of the genome. Among RNA viruses and certain DNA viruses, the genome is ... Defences against these viruses involve RNA interference from repetitive DNA sequences within archaean genomes that are related ...
  https://en.wikipedia.org/wiki/Virus
*  calcium - How intracellular Calcium signaling, gradient and its role as a universal intracellular regulator points to design
2. The amino acid sequences, together with the gene sequences, of the components that produce the Ca2+ signal and those that ... At high concentrations, however, Ca2+ causes aggregation of proteins and nucleic acids, affects the integrity of lipid ... Calcium signaling in prokaryotic and eukaryotic cells. Ca2+ homeostasis and signalling in prokaryotes 7. All prokaryotic ... CNGC, cyclic nucleotide channel; GLR, glutamate receptor; TPC1, two pore channel 1; CAS, Ca2+-sensing receptor; ACA, ...
  http://reasonandscience.heavenforum.org/t2448-howintracellular-calcium-signaling-gradient-and-its-role-as-a-universal-intracellular-regulator-points-to-design?highlight=calcium
*  ASMscience | Comparative Genomics of
... which are involved in nucleotide excision repair. The prospect of comparative genomics helping researchers resolve the ... the emerging dynamic view of the prokaryotic world. Nucleic Acids Res. 36:6688-6719.. ... catalyzes the bicarbonate-dependent oxidation of amino acids by hydrogen peroxide and the amino acid-facilitated dismutation of ... Gutman, P. D.,, P. Fuchs,, L. Ouyang,, and K.W. Minton. 1993. Identification, sequencing, and targeted mutagenesis of a DNA ...
  http://www.asmscience.org/content/book/10.1128/9781555816841.ch27
*  Oryza sativa - WikiVisually
Synonymous SNPs do not affect the sequence while nonsynonymous SNPs change the amino acid sequence of protein. The ... Because microsatellites consist of repetitive sequences, DNA polymerase may make errors at a higher rate in these sequence ... The next year Fred Sanger completed the first DNA-genome sequence, Phage Φ-X174, the first genome sequence for an archaeon, ... a somatic single nucleotide variation may also be called a single-nucleotide alteration. Single-nucleotide polymorphisms may ...
  https://wikivisually.com/wiki/Oryza_sativa
*  Frontiers | Archaeal S-Layers: Overview and Current State of the Art | Microbiology
A paracrystalline protein surface layer, commonly referred to as S-layer, is present in nearly all archaea described to date. S ... A paracrystalline protein surface layer, commonly referred to as S-layer, is present in nearly all archaea described to date. S ... Despite the numerous applied studies using bacterial S-layers, few reports have employed archaea as a study model. As such, ... Despite the numerous applied studies using bacterial S-layers, few reports have employed archaea as a study model. As such, ...
  https://www.frontiersin.org/articles/10.3389/fmicb.2017.02597/full
*  The COG database: an updated version includes eukaryotes | BMC Bioinformatics | Full Text
Neuwald AF, Liu JS, Lipman DJ, Lawrence CE: Extracting protein alignment models from the sequence database. Nucleic Acids Res ... amino acid metabolism and transport, F, nucleotide metabolism and transport, G, carbohydrate metabolism and transport, H, ... computer analysis of protein sequences predicts novel functions and suggests a chimeric origin for the archaea. Mol Microbiol ... Here, we present a major update to the COGs, with over 63 sequenced prokaryotic genomes and three genomes of unicellular ...
  https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-4-41
*  Complete genome sequence of Terriglobus saanensis type strain SP1PR4T, an Acidobacteria from tundra soil | Standards in Genomic...
tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence. Nucleic Acids Res 1997; 25:955-964. ... A repetitive DNA sequence, rhs, responsible for duplications within the Escherichia coli K-12 chromosome. J Mol Biol 1984; 177: ... mainly carbohydrates and amino acids for energy production and cell biogenesis to maintain cell integrity in cold tundra soils ... Searching the NCBI non-redundant nucleotide database for homology to 16S rRNA gene sequence of T. saanensis SP1PR4T identified ...
  https://standardsingenomics.biomedcentral.com/articles/10.4056/sigs.3036810
*  Complete genome sequence of Chitinophaga pinensis type strain (UQM 2034T)
The deduced amino acid sequence of Cpin_6813 shows a GH family 19 domain and a C-terminal deacetylase domain. Chitosanases that ... Nucleic Acids Res. 2010; 38:D346-D354 View ArticlePubMed. * Field D, Garrity G, Gray T, Morrison N, Selengut J, Sterk P, ... The sequences of the six copies of the 16S rRNA gene in the genome differ by up to five nucleotides, and differ by up to 21 ... Proposal for the domains Archaea and Bacteria. Proc Natl Acad Sci USA. 1990; 87:4576-4579 View ArticlePubMed. ...
  http://standardsingenomics.org/content/2/1/87/
*  All Classes Question Paper And Syllabus Here: M.sc Biotechnology AIIMS
Chemical synthesis of nucleic acids;. Enzyme purification and assay techniques; Techniques in cytogenetics; DNA sequencing; PCR ... of carbohydrate metabolism; Regulation of Lipid Metabolism; Regulation of Amino acid metabolism and. inborn errors of ... helical structures; b-turns/hairpin loops/-blends and other non repetitive structures; Tertiary structure. with one example of ... to function; DNA Repair; Ribosomes and rRNA; Prokaryotic transcription-initiation mechanisms and. sigma factors; Mutations and ...
  http://yoursyllabus.blogspot.com/2007/11/msc-biotechnology-aiims.html