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*  Stabilized Polymer Micelles for the Development of IT-147, an Epothilone D Drug-Loaded Formulation
... isopropyl alcohol, methyl tert-butyl ether (MTBE), acetic anhydride (Ac2O), acetone, and acetic acid were purchased from Fisher ... γ-benzyl esters with hydroxylamine and LiOH facilitates the formation of the hydroxamic acid moiety (Figure 1). Aqueous GPC and ... Acetic acid (125 eq.) and acetone (1250 eq.) were added and the reaction mixture was heated until reflux and then left to stir ... Mobile phase A consisted of water with 0.2% acetic acid, and mobile phase B consisted of methanol. Flow was isocratic at 1.2 mL ...
  https://www.hindawi.com/journals/jdd/2016/8046739/
*  Silanol - Wikipedia
19 for tert-butyl alcohol. The pKa of (3-ClC6H4)Si(CH3)2OH is 11. Because of their greater acidity, silanols can be fully ... Compared to the silyl ethers, silyl acetates are faster to hydrolyze, with the advantage that the released acetic acid is less ... deprotonated in aqueous solution, especially the arylsilanols. The conjugate base is called a siloxide or a silanolate. Despite ... The perhydroxylated silanol, sometimes called orthosilicic acid, is often discussed in vague terms, but has not been well ...
  https://en.wikipedia.org/wiki/Silanol
*  Preparation of very fine glass powder of high purity - Patent # 5340776 - PatentGenius
... butyl alcohol; the ground slurry is then frozen, and the solvent is subsequently removed from the frozen slurry by freeze- ... or acids, e.g., acetic acid and propionicacid. Monohydric, dihydric and trihydric alcohols are also suitable. An example of a ... However, tert.-butyl alcohol is highly suitable, both due to its good water solubility and also due to its high melting point. ... More preferably, the content of the organic compounds in the aqueous mixtures is 1-20%, especially 1-5%, of the organic ...
  http://www.patentgenius.com/patent/5340776.html
*  Continuous imaging of nucleic acids - Patent application
... citric acid, methanol, ethanol, n-propanol, isopropanol, iso-butyl alcohol, sec-butyl alcohol and tert-butyl alcohol. 12. The ... organic acid aqueous solutions. Suitable organic acids include monobasic carboxylic acids such as acetic acid and propionic ... citric acid, methanol, ethanol, n-propanol, isopropanol, iso-butyl alcohol, sec-butyl alcohol and tert-butyl alcohol. 20. The ... citric acid, methanol, ethanol, n-propanol, isopropanol, iso-butyl alcohol, sec-butyl alcohol and tert-butyl alcohol. [0015]The ...
  http://www.patentsencyclopedia.com/app/20100034445
*  Multi-step Preparation Technique to Recover Multiple Metabolite Compound Classes for In-depth and Informative Metabolomic...
Acetic acid. Sigma Aldrich. 49199-50ML-F. Methyl tert-butyl ether. J.T. Baker. 9042-03. ... Used to store aqueous and lipid fractions until the next step. Autosampler vials. Agilent Technologies. 5182-0545. ... Isopropyl alcohol. Sigma Aldrich. 34965-2.5L. Water. Honeywell Burdick Jackson. 365-4. ... Matyash, V., Liebisch, G., Kurzchalia, T. V., Shevchenko, A., Schwudke, D. Lipid extraction by methyl-tert-butyl ether for high ...
  https://www.jove.com/video/51670/multi-trinns-forberedelse-teknikk-for-gjenopprette-flere?language=Norwegian
*  Indian Patents. 251550:'METHOD FOR PURIFYING (METH) ACRYLIC ACID OBTAINED BY OXIDISING A GASEOUS SUBSTRATE.'
tertbutyl alcohol in the case of the manufacture. of methacrylic acid;. water vapor;. acetic acid with, in the case of the ... purged aqueous mixture contains 11.24% of acetic acid. (or 49% of the initial acetic acid) and 0.08% of. acrolein (or 0.56% of ... and/or acrolein in the case of acrylic acid; isobutane. and/or isobutene and/or tert-butyl alcohol and/or. methacrolein in the ... is manufactured, acetic acid in the case of the. manufacture of acrylic acid, or acetic acid and acrylic. acid in the case of ...
  http://www.allindianpatents.com/patents/251550-method-for-purifying-meth-acrylic-acid-obtained-by-oxidising-a-gaseous-substrate
*  Knorr pyrrole synthesis - Wikipedia
... and tertiary-butyl groups can be removed by treatment with trifluoroacetic acid, or boiling aqueous acetic acid. R1 and R3 (as ... and the reaction is noteworthy in that even the highly hindered tert-butyl alcohol gives very high yields in this synthesis. ... Benzyl or tert-butyl acetoacetates also work well in this system, and with close temperature control, the tert-butyl system ... or carboxylic acid functionality by the use of stoichiometric sulfuryl chloride in glacial acetic acid. Alternatively, the ...
  https://en.wikipedia.org/wiki/Knorr_pyrrole_synthesis
*  Carbocyclic- And Heterocyclic-Substituted Hexahydropyrano[3,4-d][1,3]Thiazin-2-Amine Compounds - PFIZER INC.
Step 1. Synthesis of (3-{[tert-butyl(dimethyl)silyl]oxy}propyl)magnesium bromide (C10). (3-Bromopropoxy)(tert-butyl) ... A polymer such as cross-linked polyacrylic acid, polyvinyl alcohol, hyaluronic acid, a cellulosic polymer, for example, ... and sulfuric acids, and organic acids such as acetic, benzenesulfonic, benzoic, citric, ethanesulfonic, fumaric, gluconic, ... To a solution of crude C82 in tetrahydrofuran (780 mL) was added aqueous hydrochloric acid (2 M, 780 mL, 0.78 mol). The mixture ...
  http://www.freepatentsonline.com/y2016/0002264.html
*  Патент USA US3061526
... studies of telomycin lected and eluted with a solution of equal parts of meth between an upper phase of tert-butyl alcohol and ... 1 Crystals from aqueous-acid re?ux, 3 Solubility of Types I and II are crude initial solubility values since solutions ... was de veloped on paper sheets using the techniques of two dimensional paper chromatography using a butanol-water acetic acid ( ... hydrochloric acid for 5 7 hours to contain the amino acids glycine, a-alanine, threonine and aspartic acid. A sample of ...
  https://www.docme.ru/doc/3742782/patent-usa-us3061526
*  Oseltamivir total synthesis - Wikipedia
In the second one-pot operation, trifluoroacetic acid is employed first to deprotect the tert-butyl ester of (6); any excess ... 2-amino alcohol. The water-immiscible solvents methyl tert-butyl ether and acetonitrile are used to simplify the workup ... The isocyanate derivative then reacts with acetic acid to yield the desired acetylamino moiety found in (1). This domino ... procedure, which involved stirring with 1 M aqueous ammonium sulfate. Reduction on palladium, promoted by ethanolamine, ...
  https://en.wikipedia.org/wiki/Oseltamivir_total_synthesis
*  Use of tris(hydroxymethyl) aminomethane for the stabilization of peptides, polypeptides and proteins - Patent # 8710181 -...
Examples of branched alcohols are 2-propanol and tert-butyl alcohol. Examples of cyclic alcohols are cyclopropyl alcohol and 2- ... or C.sub.1-6-alkanoic acid, such as acetic acid, C.sub.2-6-glycol, C.sub.3-7-polyalcohol including sugars or mixtures thereof. ... fractionating the aqueous solution of (a) by ion-exchange chromatography; and (c) fractioning the aqueous solution of (b) by ... iso-butyl, sec-butyl, tert-butyl, pentyl, isopentyl, and the like (cf. Morrison & Boyd, Organic Chemistry, 4.sup.th Ed.).. The ...
  http://www.patentgenius.com/patent/8710181.html
*  Stable NO-delivering compounds - Patent # 6359167 - PatentGenius
S-nitrosyl group and a free alcohol or a free thiol group. Also disclosed is a method of preparing the NO-releasing compounds. ... in the presence of an acid, e.g. HCl, acetic acid,H.sub.3 PO.sub.4 and the like, at a temperature from about -20.degree. C. to ... Suitablenitrosylating agents include SNAP, tert-butyl nitrite, acidified nitrite, S-nitrosothiols, organic nitrite, nitrosyl ... 4. The compound of claim 3 wherein the free alcohol group(s) and the S-nitrosyl group(s) are each bonded to a methylene group. ...
  http://www.patentgenius.com/patent/6359167.html
*  Patent US8173198 - Deposition of metal oxides onto surfaces as an immobilization vehicle for ... - Google Patents
Tert-Butyl hydroperoxide (70% aqueous, 6 ml, 45 mM) was added and the mixture was stirred at room temperature for 2 hours. The ... Synthesis and Column Purification of mPEG2K Acetamido-Tris-Alcohol. The Methyl PEG2K-Acetic Acid intermediate reaction product ... chromic acid in sulfuric acid, potassium hydroxide in methanol, hydrogen peroxide in sulfuric acid, nitric acid in sulfuric ... vinyl phosphoric acid), pyrophosphate, poly(acrylic acid), poly(vinyl alcohol), polyethylene glycol comprising functionalities ...
  http://www.google.ca/patents/US8173198
*  New FTY720-docetaxel nanoparticle therapy overcomes FTY720-induced lymphopenia and inhibits metastatic breast tumour growth |...
... t-Boc di-tert-butyl dicarbonate, TFA trifluoroacetic acid, PVA poly vinyl alcohol ... and separated by thin layer chromatography on silica gel G60 plates using 1-butanol/ethanol/acetic acid/water (80:20:10:20, v/v ... They were then stained with 5 µL of Annexin FITC (BD biosciences, UK) and 5 µg/mL aqueous solution of propidium iodide (BD ... First, the amine group of FTY was protected with di-tert-butyl dicarbonate (t-Boc). It was then conjugated onto the PLGA ...
  https://link.springer.com/article/10.1007%2Fs10549-017-4380-8
*  US Patent # 9,663,456. Intermediate of tapentadol - Patents.com
... formic acid, acetic acid, oxalic acid, succinic acid, tartaric acid, mandelic acid, fumaric acid, lactic acid, citric acid, ... butyl acetate, sec-butyl acetate, tert-butyl acetate etc., halogenated solvents like carbon tetrachloride, chlorobenzene, ... Citric acid (0.85 gm) is added to the filtrate and stirred at room temperature for 45 minutes. Organic and aqueous layers are ... The suitable solvent may be selected from group comprising C.sub.1-C.sub.4 alcohols like methanol, ethanol, isopropyl alcohol, ...
  http://patents.com/us-9663456.html
*  US4193889A - Microencapsulation with modified aliphatic polyisocyanates - Google Patents
1,000 parts by weight of hexamethylene-1,6-diisocyanate (5.952 mole) and 50 parts by weight of tert.-butyl alcohol (0.676 mole ... The batch is then neutralised with semi-concentrated acetic acid. The diameter of the microcapsules amounts to between 20 and ... emulsification aids are preferably added to the aqueous phase. Examples are protective colloids such as polyvinyl alcohol, ... glycerol or trimethylol propane or carboxylic acids such as succinic acid, adipic acid, sebacic acid, in proportions of from ...
  https://patents.google.com/patent/US4193889
*  Patent US5981073 - Compounds based on dibenzoylresorcinol, and related compositions and articles - Google Patents
... compounds are disclosed wherein the dibenzoylresorcinol is bonded to the residue of either an alcohol or a carboxylic acid ... Acetate III (3.90 g, 10 mmol) and 5 drops of concentrated hydrochloric acid were added to about 15 mL of tert-butyl alcohol. ... For example, if acetic acid is employed, then R2 would be a methyl group; and if propionic acid is used, then R2 would be an ... The aqueous phase was decanted from the solidified organic phase. About 100 mL of ethanol was added, and the resulting slurry ...
  http://www.google.com/patents/US5981073?dq=6106459
*  Patent US4340535 - Cytotoxic products formed by covalent bonding of the A chain of ricin with ... - Google Patents
The medium is acidified up to pH 4.5 by adding acetic acid. A precipitate is formed which is recovered by decantation and then ... in particular the tert.-butyl group. ... 0.47 ml of a 0.1 M aqueous solution of hydroxylamine, pH=8.0, ... by volume of a water-miscible organic solvent such as an alcohol, in particular tertiary butanol. ... This acid is obtained in two steps from 3-(2-pyridyl-disulphanyl) propionic acid without purification of the intermediate. ## ...
  http://www.google.com.au/patents/US4340535
*  US4822731A - Process for labeling single-stranded nucleic acids and hybridizaiton probes - Google Patents
Preferably, the labeled nucleic acid is a single-stranded hybridization probe for detecting nucleic acid sequences capable of ... nucleic acid to form a complex and activating the complex to cause covalent bonding between the reagent and the nucleic acid. ... Nucleic acids may be labeled by complexing the alkylating moiety of a labeling reagent into a single-stranded ... hybridizing with a hybridizing region of the nucleic acid. Also preferably the label moiety is non-radioactive. The labeling ...
  https://patents.google.com/patent/US4822731A/en
*  DiVA - Søkeresultat
... and metal compound-alcohol initiators such as PbO, SnO, tin bis(2-ethyl hexanoate) in the presence of tert-butyl benzyl alcohol ... Final succinic acid concentrations were in the range of 25-40 g L-1. Acetic and pyruvic acid were the only other products ... The structure of aqueous solutions of some dihydrogen orthophosphates by laser Raman spectroscopy1987Inngår i: Journal of ... Organic acid inhibition due to the produced succinic acid on the other hand significantly reduced succinic acid productivity ...
  http://www.diva-portal.org/smash/resultList.jsf?dswid=-6003&searchType=SUBJECT&language=no&onlyFullText=false&af=%5B%5D&aq=%5B%5B%7B%22categoryId%22%3A%2211634%22%7D%5D%5D
*  DiVA - Search result
... and metal compound-alcohol initiators such as PbO, SnO, tin bis(2-ethyl hexanoate) in the presence of tert-butyl benzyl alcohol ... Final succinic acid concentrations were in the range of 25-40 g L-1. Acetic and pyruvic acid were the only other products ... The structure of aqueous solutions of some dihydrogen orthophosphates by laser Raman spectroscopy1987In: Journal of Crystal ... ferulic acid, sinapic acid, caffeic acid, p-coumaric acid) and sugar residues in plant cell walls. Based on their specificity ...
  http://www.diva-portal.org/smash/resultList.jsf?searchType=SUBJECT&language=en&onlyFullText=false&af=%5B%5D&aq=%5B%5B%7B%22categoryId%22%3A%2211634%22%7D%5D%5D
*  US Patent # 5,631,167. Capsule chemistry analytical methods employing dioxetane chemiluminescence - Patents.com
... and a catalytic amount of sulfuric acid for a total of 9 hours. The excess alcohol was removed by vacuum distillation. The ... The solution was cooled to room temperature and neutralized with acetic acid (1 eq.). The mixture was extracted with ethyl ... Compositions for providing enhanced chemiluminescence comprise a dioxetane as described above in an aqueous solution, and a non ... 3-Chloropropyl 3-hydroxybenzoate (67.5 g) was dissolved in anhydrous DMF (100 mL) followed by and t-butyl-dimethylsilyl ...
  http://patents.com/us-5631167.html
*  PREPARATION OF ALKYL ESTERS OF N-PROTECTED OXO-AZACYCLOALKYLCARBOXYLIC ACIDS - Patent application
... carboxylic acid tert-butyl ester)-2-((S)-1-benzyloxycarbonyl-pyrrolidin-3-ylcarbamoyl)-piperidine-1-- carboxylic acid tert- ... gas or in aqueous solution), sulfuric acid, and nitric acid. Suitable organic acids include carboxylic acids, alkylsulfonic ... Meanwhile a 20% acetic acid in MeOH solution was prepared by adding 40 mL of acetic acid to 160 mL MeOH. This solution was ... NMR with internal standard showed 35 g. (116 mmol, 79% yield over two steps) of alcohol. 1H NMR (500 MHz, CDCl3): δ 4.75 (bs, ...
  http://www.patentsencyclopedia.com/app/20120053350
*  Patent US6930197 - Antihistaminic piperidine derivatives and intermediates for the preparation ... - Google Patents
... benzene acetic acid ester to provide a corresponding [4-(4-halo-1-oxo-butyl)phenyl]benzene acetic acid ester of the formula: ... The reaction is typically carried out in an aqueous lower alcohol solvent, such as methanol, ethanol, isopropyl alcohol, n- ... n-butyl, sec-butyl, isobutyl, tert-butyl, and straight- and branched-chain pentyl and hexyl. ... 4-(cyclopropylcarbonyl)phenyl]butyl-propanedioic acid, diethyl ester. *[4-(cyclopropylcarbonyl)phenyl]butyl-propanedioic acid, ...
  http://www.google.com/patents/US6930197
*  WO2013106037A1 - Polymer-based optically variable devices - Google Patents
... butyl, isobutyl, sec-butyl, tert-butyl, 2-ethylhexyl and cyclohexyl alcohols, and with saturated lower polyhydric alcohols such ... saturated acids such as acetic, propionic, butyric, valeric, caproic and stearic, (ii) unsaturated acids such as acrylic, alpha ... isodecyl alcohol, oleyl alcohol, stearyl alcohol, epoxy resins and polybutadiene-derived polyols. ... high phobicity to aqueous solutions and (c) high glass transition chemistry. Based on these principles, experimental work has ...
  https://patents.google.com/patent/WO2013106037A1/en