MitochondriaMitochondria, LiverMitochondria, HeartApoptosisCaspasesApoptosis Regulatory ProteinsMitochondria, MuscleCaspase 3Proto-Oncogene Proteins c-bcl-2Mitochondrial Proteinsbcl-2-Associated X ProteinCytochromes cInhibitor of Apoptosis ProteinsDNA FragmentationMitochondrial MembranesMembrane Potential, MitochondrialApoptosis Inducing FactorCell Line, TumorMitochondrial SwellingIn Situ Nick-End LabelingCaspase 9Reactive Oxygen SpeciesCell SurvivalIntracellular MembranesOxidative PhosphorylationX-Linked Inhibitor of Apoptosis ProteinSignal TransductionCytochrome c GroupCaspase InhibitorsCells, CulturedCaspase 8Enzyme Activationbcl-X ProteinOxygen ConsumptionCASP8 and FADD-Like Apoptosis Regulating ProteinCell RespirationMitochondrial Membrane Transport ProteinsCell LineDNA, MitochondrialTumor Suppressor Protein p53Blotting, WesternTumor Cells, CulturedUncoupling AgentsFas Ligand ProteinElectron Transport Complex IVOxidative StressAmino Acid Chloromethyl KetonesAdenosine TriphosphateCell DeathCysteine Proteinase InhibitorsBH3 Interacting Domain Death Agonist ProteinOligomycinsMicroscopy, ElectronAnnexin A5Proto-Oncogene ProteinsCarrier ProteinsCytosolCell ProliferationMolecular Sequence DataProtein TransportOxidation-ReductionMembrane ProteinsFlow CytometryRotenoneMalatesEnzyme InhibitorsCalciumPoly(ADP-ribose) PolymerasesTransfectionAntineoplastic AgentsTime FactorsCell CycleAtractylosideKineticsbcl-2 Homologous Antagonist-Killer ProteinAntimycin AModels, BiologicalDose-Response Relationship, DrugCarbonyl Cyanide p-TrifluoromethoxyphenylhydrazoneJurkat CellsHydrogen PeroxideHeLa CellsRNA, Small InterferingMembrane PotentialsAmino Acid SequenceCell NucleusPermeabilityMitochondrial ADP, ATP TranslocasesMutationElectron TransportRNA, MessengerPhosphorylationCell DivisionBiological TransportNecrosisTNF-Related Apoptosis-Inducing LigandHL-60 CellsRats, Sprague-DawleySaccharomyces cerevisiaeDown-Regulation