Antiphospholipid antibodies definition | Drugs.com
Definition of antiphospholipid antibodies. Provided by Stedman's medical dictionary and Drugs.com. Includes medical terms and ... antiphospholipid antibodies. Definition: antibodies directed against phosphorylated polysaccharide esters of fatty acids, ... includes lupus anticoagulant, Venereal Disease Research Laboratories, and anticardiolipin antibodies. Associated with immune- ...https://www.drugs.com/dict/antiphospholipid-antibodies.html
Inter-assay variation in antiphospholipid antibody testing: Ingenta Connect
We evaluated inter-assay variation in anticardiolipin antibody status, comparing three centres, and using different assays ...http://www.ingentaconnect.com/content/bsc/bjo/2002/00000109/00000003/art00014
PatientsLikeMe | Antiphospholipid antibody syndrome symptoms, treatments & patient forums | PatientsLikeMe
640 patients with antiphospholipid antibody syndrome experience fatigue, Pain, depressed mood, anxious mood, and insomnia and ... Find the most comprehensive real-world symptom and treatment data on antiphospholipid antibody syndrome at PatientsLikeMe. ... and Oxycodone to treat their antiphospholipid antibody syndrome and its symptoms. ... What is antiphospholipid antibody syndrome?. Antiphospholipid syndrome, Hughes syndrome, or antiphospholipid antibody syndrome ...https://www.patientslikeme.com/conditions/515-antiphospholipid-antibody-syndrome
Update on Antiphospholipid Antibody Syndrome Management | IntechOpen
Update on Antiphospholipid Antibody Syndrome Management , IntechOpen, Published on: 2012-04-20. Authors: Rocco Manganelli, ... Update on Antiphospholipid Antibody Syndrome Management. By Rocco Manganelli, Salvatore Iannaccone, Serena Manganelli and Mario ... Medicine » Immunology, Allergology and Rheumatology » 'Antiphospholipid Syndrome', book edited by Alena Bulikova, ISBN 978-953- ...https://www.intechopen.com/books/antiphospholipid-syndrome/update-on-antiphospholipid-syndrome-antibody-management/
Lupus anticoagulants and antiphospholipid antibodies | University of Maryland Medical Center
Lupus anticoagulants and antiphospholipid antibodies. Toggle: English / Spanish Definition. Lupus anticoagulants are antibodies ... Antibodies to beta-2-glypoprotein I (Beta2-GPI). Your health care provider may check for antiphospholipid antibody syndrome ( ... ANTIPHOSPHOLIPID ANTIBODY SYNDROME (APS) In general, you will need long-term treatment with a blood thinner for a long time if ... The antiphospholipid antibodies (aPL) cause the tests to be abnormal in the laboratory. ...https://www.umm.edu/Health/Medical/Ency/Articles/Lupus-anticoagulants
Catastrophic Antiphospholipid Antibody Syndrome - ONA
Antiphospholipid Antibody Syndrome. *Serum HPV Antibody Levels May Be a Biomarker for Recurrent HPV-associated Oropharyngeal ... Catastrophic antiphospholipid syndrome (CAPS) is a life-threatening complication of antiphospholipid antibody syndrome with (a ... laboratory confirmation of antiphospholipid antibodies (aPL): lupus anticoagulant (LA) test; anticardiolipin antibody (aCL) by ... Sapporo criteria for antiphospholipid antibody syndrome (APS). Definite APS if at least one clinical and one laboratory ...http://www.oncologynurseadvisor.com/critical-care-medicine/catastrophic-antiphospholipid-antibody-syndrome/article/587057/
British Library EThOS: Antiphospholipid antibodies and the protein C pathway
The antiphospholipid syndrome (APS) is characterised by the presence of antiphospholipid antibodies (aPA) associated with ... of protein C pathway defects in patients with aPA and to study clinical correlates examine the mechanisms of antiphospholipid ...http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.498607
Antiphospholipid antibody syndrome - The Clinical Advisor
Overview of APS, with details on drug-related antibodies.) Pham, C, Shen, YM. "Antiphospholipid antibodies and malignancy". ... Antiphospholipid Antibody Syndrome (Hughes Disease) ICD-9 286.5. Are You Confident of the Diagnosis?. What you should be alert ... Weinstein, S, Piette, W. "Cutaneous manifestations of antiphospholipid antibody syndrome". Hematol Oncol Clinics N Am. vol. 22 ... "Antiphospholipid antibodies--we are not quite there yet". Blood Reviews. vol. 25. 2011. pp. 97-106. ...http://www.clinicaladvisor.com/dermatology/antiphospholipid-antibody-syndrome/article/593082/
Archives of Antiphospholipid antibody syndrome (APS) from the Autoimmune Disorders Forum - MedHelp
The Archives of Antiphospholipid antibody syndrome (APS) Questions. Listed below are our archive of questions and answers from ... 2009 Antiphospholipid antibody syndrome (APS) Q&A *Why does my warfarin dosage keep on rising???? ... 2008 Antiphospholipid antibody syndrome (APS) Q&A *please help me decipher these results ...https://www.medhelp.org/topics/show/2382
Complement C5-inhibitor rEV576 (coversin) ameliorates in-vivo effects of antiphospholipid antibodies. | Sigma-Aldrich
Complement C5-inhibitor rEV576 (coversin) ameliorates in-vivo effects of antiphospholipid antibodies.. [Z Romay-Penabad, A L ... Activation of the complement cascade is an important mechanism for antiphospholipid antibody-mediated thrombosis. We examined ... The data confirm involvement of complement activation in antiphospholipid antibody-mediated thrombogenesis and suggest that ... on antiphospholipid antibody-mediated tissue factor up-regulation and thrombosis. Groups of C57BL/6J mice (n=5) received either ...https://www.sigmaaldrich.com/catalog/papers/25228739
Catastrophic antiphospholipid antibody syndrome in a young woman in the postpartum period.
... as well as deranged coagulation profile and PTT mixing studies aided in the diagnosis of catastrophic antiphospholipid antibody ... Positive anticardiolipin antibodies, lupus anticoagulant, and anti-B2 glycoprotein-I, ...http://www.biomedsearch.com/nih/Catastrophic-antiphospholipid-antibody-syndrome-in/21186706.html
miscarriage, pregnancy, menstruation, Antiphospholipid antibody syndrome, polycystic ovarian syndrome
Antiphospholipid antibody syndrome, a blood-clotting disorder, is also associated with recurrent first-trimester miscarriages. ... It is diagnosed by testing blood levels of particular antibodies that need to be positive at two different times. It is ...http://awomanshealth.com/miscarriages/
A systematic review of secondary thromboprophylaxis in patients with antiphospholipid antibodies
Antibodies, Antiphospholipid /blood; Anticoagulants /therapeutic use; Antiphospholipid Syndrome /blood /complications; Aspirin ... defined as persistent antiphospholipid antibodies (medium to high anticardiolipin antibody titres and /or lupus anticoagulant ... A systematic review of secondary thromboprophylaxis in patients with antiphospholipid antibodies. Ruiz-Irastorza G, Hunt B J, ... Patients with venous embolism or stroke and a single positive antiphospholipid antibodies that did not persist were at ...http://www.crd.york.ac.uk/crdweb/ShowRecord.asp?LinkFrom=OAI&ID=12008000242
Genetic Risk Factors Associated With Antiphospholipid Antibody Syndrome | Clinical Research Trial Listing ( Antiphospholipid...
New life-saving treatments for Antiphospholipid syndrome in clinical trial on Genetic Risk Factors Associated With ... Antiphospholipid antibody syndrome (APS) is characterized by the presence of antiphospholipid antibodies, which are proteins in ... Genetic Risk Factors Associated With Antiphospholipid Antibody Syndrome Brief description of study. ... Clinical problems associated with antiphospholipid antibodies include an increased risk for the formation of blood clots in the ...https://www.centerwatch.com/clinical-trials/listings/37423/antiphospholipid-syndrome-genetic-risk-factors-associated/?&radius=50
How to treat women with antiphospholipid antibodies in pregnancy? | Annals of the Rheumatic Diseases
1994) Antiphospholipid antibodies in predicting adverse pregnancy outcome. A prospective study. Ann Intern Med 120:470-475, . ... 1998) Antiphospholipid antibodies and reproductive outcome: the current state of affairs. J Reprod Immunol 38:75-87, . ... 1997) Pregnancy loss in the antiphospholipid antibody syndrome-a possible thrombogenic mechanism. N Engl J Med 337:154-160. ... 1995) The management of thrombosis in the antiphospholipid-antibody syndrome. N Engl J Med 332:993-997, . ...http://ard.bmj.com/content/60/1/1
Antiphospholipid antibodies induce a pro-inflammatory response in first trimester trophoblast via the TLR4/MyD88 pathway. -...
Women with antiphospholipid antibodies (aPL) are at risk for recurrent miscarriage, pre-eclampsia, and pre-term labor. aPL ... Antiphospholipid antibodies induce a pro-inflammatory response in first trimester trophoblast via the TLR4/MyD88 pathway.. ... Antiphospholipid antibodies induce a pro-inflammatory response in first trimester trophoblast via the TLR4/MyD88 pathway ... Antiphospholipid antibodies induce a pro-inflammatory response in first trimester trophoblast via the TLR4/MyD88 pathway ...https://www.ncbi.nlm.nih.gov/pubmed?term=19614626
Antiphospholipid Antibody Syndrome
The antiphospholipid antibody tests considered in this analysis are lupus anticoagulant, the anticardiolipin antibody, and the ... Antiphospholipid antibodies include anticardiolipin antibodies, the lupus anticoagulant, and antibeta-2 glycoprotein 1 ... Antiphospholipid antibodies can be detected in the general population with a frequency of 3-5%, with higher percentages in ... Patients with antiphospholipid antibodies may also demonstrate false positive tests for syphilis in the VDRL assay. ...https://www.endocrinologyadvisor.com/labmed/antiphospholipid-antibody-syndrome/article/614614/
Antiphospholipid Antibodies and Systemic Scleroderma [Turk J Hematol]
Antiphospholipid Antibodies and Systemic Scleroderma. Awa Oumar Tour 1, Fatimata Ly2, Abibatou Sall1, Alassane Diatta3, Macoura ... Antiphospholipid Antibodies and Systemic Scleroderma. Turk J Hematol. 2013; 30(1): 32-36. Corresponding Author: Awa Oumar Tour ... Objective: Antiphospholipid antibodies (APLs) could be associated with an increased risk of vascular pathologies in systemic ... The most frequently encountered antibody was IgG anti-β2 GPI (37.5% of the patients), followed by anticardiolipins (17.5%) and ...http://www.tjh.com.tr/jvi.aspx?pdir=tjh&plng=eng&un=TJH-46503&look4=
The Influence of Antiphospholipid Antibodies on the Relationship Between Hyperurecemia, Gout and Metabolic Syndrome - Full Text...
The Influence of Antiphospholipid Antibodies on the Relationship Between Hyperurecemia, Gout and Metabolic Syndrome (URIC). The ... The Influence of Antiphospholipid Antibodies on the Relationship Between Hyperurecemia, Gout and Metabolic Syndrome. ... In the present study, the investigators will analyze the presence of antiphospholipid antibodies in the serum of the patients ... In the present study, we'll analyze the presence of antiphospholipid antibodies in the serum of the patients with gout/ ...https://clinicaltrials.gov/show/NCT01818505
Recurrent stroke and multi-infarct dementia in systemic lupus erythematosus: association with antiphospholipid antibodies.
Harris EN, Englert H, Derve G, Hughes GR, Gharavi A. Antiphospholipid antibodies in acute Guillain-Barré syndrome. Lancet. 1983 ... Recurrent stroke and multi-infarct dementia in systemic lupus erythematosus: association with antiphospholipid antibodies.. R A ... Central retinal artery occlusion in Sneddon's disease associated with antiphospholipid antibodies. Am J Ophthalmol. 1986 Jul 15 ... Anticardiolipin antibodies: isotype distribution and phospholipid specificity. Ann Rheum Dis. 1987 Jan;46(1):1-6. [PMC free ...http://pubmedcentralcanada.ca/pmcc/articles/PMC1002208/?lang=en-ca
Aspirin inhibits endothelial cell activation induced by antiphospholipid antibodies
Summary Antiphospholipid antibodies (APLA) have been shown to activate endothelial cells (EC) in vitro, as documented by an ... Antiphospholipid antibodies (APLA) have been shown to activate endothelial cells (EC) in vitro, as documented by an increased ... Currently, treatment of patients with the antiphospholipid syndrome includes aspirin, particularly for women with recurrent ...https://insights.ovid.com/thrombosis-haemostasis/jthrh/2004/07/000/aspirin-inhibits-endothelial-cell-activation/23/00149457
Clot lysis time and thrombin activatable fibrinolysis inhibitor in severe preeclampsia with or without associated...
... with or without associated antiphospholipid syndrome (APS). The study groups ... Antibodies, Antiphospholipid / blood*. Antiphospholipid Syndrome / blood*, complications, genetics. Blood Coagulation Tests. ... 0/Antibodies, Antiphospholipid; EC 22.214.171.124/Carboxypeptidase U From MEDLINE®/PubMed®, a database of the U.S. National Library ... The study groups included 82 pregnant patients without antiphospholipid antibodies with severe preeclampsia (PE group) and 10 ...http://www.biomedsearch.com/nih/Clot-lysis-time-thrombin-activatable/20594598.html
Eculizumab to Enable Renal Transplantation in Patients With History of Catastrophic Antiphospholipid Antibody Syndrome - Full...
Eculizumab to Enable Renal Transplantation in Patients With History of Catastrophic Antiphospholipid Antibody Syndrome. The ... Catastrophic Antiphospholipid Antibody Syndrome (CAPS) is a rare condition in which life-threatening blood clots form in ... Genetic and Rare Diseases Information Center resources: Antiphospholipid Syndrome Catastrophic Antiphospholipid Syndrome ... Antiphospholipid Syndrome. Disease. Pathologic Processes. Renal Insufficiency, Chronic. Renal Insufficiency. Kidney Diseases. ...https://clinicaltrials.gov/ct2/show/NCT01029587
Pilot Study of Cyclophosphamide in Patients With Life-Threatening Systemic Lupus Erythematosus or Antiphospholipid Antibody...
Antibodies. Antibodies, Antiphospholipid. Immunosuppressive Agents. Immunologic Factors. Physiological Effects of Drugs. ... Diagnosis of antiphospholipid antibody syndrome by the Hughes criteria; must show severity by ongoing symptoms or signs of ... antiphospholipid antibody syndrome. arthritis & connective tissue diseases. immunologic disorders and infectious disorders. ... Pilot Study of Cyclophosphamide in Patients With Life-Threatening Systemic Lupus Erythematosus or Antiphospholipid Antibody ...https://clinicaltrials.gov/ct2/show/NCT00010400
FRI0173 Multiple antiphospholipid-antibody-tests improve the laboratory diagnostic in the antiphospholipid syndrome | Annals of...
FRI0173 Multiple antiphospholipid-antibody-tests improve the laboratory diagnostic in the antiphospholipid syndrome ... FRI0173 Multiple antiphospholipid-antibody-tests improve the laboratory diagnostic in the antiphospholipid syndrome ... were positive for other phospholipid-antibody-specificities, in 22 (33%) the antibody-concentrations were even high. Antibodies ... Background Examining patients with clinical features of the antiphospholipid-antibody-syndrome (APS), anticardiolipin ...http://ard.bmj.com/content/60/Suppl_1/A98.1
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