*  Structural glycobiology of antibody recognition in xenotransplantation and cancer immunotherapy
... many tumor-associated carbohydrate antigens are broadly expressed at very high densities on the cell surface of primary and ... Carbohydrate antigens recognized by "natural" or preformed and elicited antibodies are central to transplantation/transfusion ... metastatic tumors, but the same carbohydrates occur at much lower levels and are typically restricted to a few cell types in ... Often the minimal carbohydrate epitopes are located at the terminal end of more complex oligosaccharide chains, which result in ...
  https://espace.curtin.edu.au/handle/20.500.11937/17581
*  Structure and function of the Ca antigen. - Semantic Scholar
The carbohydrate has a very simple structure: it is composed almost entirely of tetra- tri- and disaccharides having the ... The presence of the Ca antigen in malignant tumours may thus be a reflection of metabolic conditions that are known to be ... At least 95% of the carbohydrate is 0-glycosidically linked to the polypeptide which contains high proportions of glycine, ... the antigen is produced constitutively in vitro; but in one that has been examined, its synthesis can be induced by high ...
  https://www.semanticscholar.org/paper/Structure-and-function-of-the-Ca-antigen-Bramwell-Bhavanandan/eceaa3ee9d46f453070a6eefb89be3cbfdf547b4
*  Tumor Marker Carbohydrate Antigen 125 Predicts Adverse Outcome After Transcatheter Aortic Valve Implantation - American College...
Tumor Marker Carbohydrate Antigen 125 Predicts Adverse Outcome After Transcatheter Aortic Valve Implantation. May 20, 2013 ... YOU ARE HERE: Home , Latest in Cardiology , Tumor Marker Carbohydrate Antigen 125 Predicts Adverse Outcome After Transcatheter ... What is the predictive value of tumor marker carbohydrate antigen 125 (CA125) before and after transcatheter aortic valve ...
  http://www.acc.org/latest-in-cardiology/journal-scans/2013/05/20/16/03/tumor-marker-carbohydrate-antigen-125-predicts-adverse-outcome
*  Tumor Marker Carbohydrate Antigen 125 Predicts Adverse Outcome After Transcatheter Aortic Valve Implantation | JACC:...
Tumor marker carbohydrate antigen 125 (CA125) is an emerging cardiac biomarker. In heart failure (HF), CA125 has shown to be ... Objectives This study sought to predict the value of tumor marker carbohydrate antigen 125 (CA125) before and after ... Tumor Marker Carbohydrate Antigen 125 Predicts Adverse Outcome After Transcatheter Aortic Valve Implantation ... Tumor Marker Carbohydrate Antigen 125 Predicts Adverse Outcome After Transcatheter Aortic Valve Implantation ...
  http://interventions.onlinejacc.org/content/6/5/487
*  KAKEN - Research Projects | Development of immunotherapy for brain tumors targeting carbohydrate antigens of glycolipids ...
Development of immunotherapy for brain tumors targeting carbohydrate antigens of glycolipids. Research Project ... Publications] T.Yamaki: 'The requirement of host immune response to tumor cells to achieve tumor eradication by intratumoral ... Publications] Yamaki T.: 'The requirement of host immune response to tumor cells to achieve tumor eradication by intratumoral ... Publications] T.Yamaki: 'The requirement of host immune response to tumor cells to achieve tumor eradication by intratumoral ...
  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-05807129/
*  ivd-test-reagent-kits-immunoassay-tumor-marker-carbohydrate-antigen-ca-27.29
Carbohydrate Antigen 27.29) Determination Reagents" , "Reagents, Immunoassay, Tumor Marker, Carbohydrate Antigen CA 27.29" ... IVD Test Reagent/Kits, Immunoassay, Tumor Marker, Carbohydrate Antigen CA 27.29. Definition : Immunoassay reagents intended to ... Home > Specialties > IVD Test Reagent/Kits, Immunoassay, Tumor Marker, Carbohydrate Antigen CA 27.29 ... a carbohydrate-related tumor marker. The detection of the tumor marker CA 27.29 is mostly used in monitoring therapy and ...
  http://www.medicalproductguide.com/term/5559/ivd-test-reagent-kits-immunoassay-tumor-marker-carbohydrate-antigen-ca-27.29
*  ivd-test-reagent-kits-immunoassay-tumor-marker-carbohydrate-antigen-ca-19-9
Carbohydrate Antigen 19-9) Determination Reagents" , "Reagents, Immunoassay, Tumor Marker, Carbohydrate Antigen CA 19-9" ... Home > Specialties > IVD Test Reagent/Kits, Immunoassay, Tumor Marker, Carbohydrate Antigen CA 19-9 ... IVD Test Reagent/Kits, Immunoassay, Tumor Marker, Carbohydrate Antigen CA 19-9. ... a blood-group carbohydrate-related tumor marker. The detection of the tumor marker CA 19-9 is mostly in diagnosis and ...
  http://www.medicalproductguide.com/term/4900/ivd-test-reagent-kits-immunoassay-tumor-marker-carbohydrate-antigen-ca-19-9
*  Oncotarget | Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in...
... a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects ... a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects ... Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast ... Hakomori S. Tumor-associated carbohydrate antigens defining tumor malignancy: basis for development of anti-cancer vaccines. ...
  http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=21959&path%5B%5D=69621
*  Carbohydrates in Drug Design and Discovery (RSC Publishing)
... this book comprehensively covers the new and recent discoveries in the area of carbohydrate drug discovery.Carbohydrates in ... and the use of synthetic ligands based on carbohydrates as drugs has received much attention. Focussing on drug discovery from ... In recent years there has been increasing evidence of the importance of carbohydrates and glycoconjugates in biomedical ... Boosting Humoral Immune Responses to Tumor-associated Carbohydrate Antigens with Virus-like Particles. Zhaojun Yin and Xuefei ...
  http://pubs.rsc.org/en/content/ebook/978-1-84973-939-9
*  Frontiers | Carbohydrate-Mimetic Peptides for Pan Anti-Tumor Responses | Immunology
... consequences of mimicking tumor associated carbohydrate antigens and the notion of reverse engineering to develop carbohydrate ... consequences of mimicking tumor associated carbohydrate antigens and the notion of reverse engineering to develop carbohydrate ... Here, we discuss our experience in bringing a tumor-associated carbohydrate mimetic peptide to the clinic. Emphasis is placed ... Here, we discuss our experience in bringing a tumor-associated carbohydrate mimetic peptide to the clinic. Emphasis is placed ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2014.00308/full
*  What Makes a Cancer Cell a Cancer Cell? - Holland-Frei Cancer Medicine - NCBI Bookshelf
Tumor-associated carbohydrate antigens can also be classified by the cell types expressing them as those (1) expressed on only ... Tumor-associated carbohydrate antigens can be classified into three groups38: (1) epitopes expressed on both glycolipids and ... Clinical trials of mucin-derived vaccines are underway.58 Some mucin antigens are shed from tumor cells and can be detected in ... by the fact that many of the monoclonal antibodies developed to tumor-cell-associated antigens recognize these carbohydrate ...
  https://www.ncbi.nlm.nih.gov/books/NBK12516/
*  Faculty for Chemistry and Pharmacy LMU Munich - Prof. Dr. Anja Hoffmann-Röder
Synthesis of carbohydrates, peptides and glycokonjugates. *Tumor-associated carbohydrate antigens and cancer vaccines ... A. Hoffmann-Röder, J. Schoenhentz, S. Wagner, E. Schmitt, "Perfluoroalkylated amphiphilic MUC1 glycopeptide antigens as tools ... "Synthetic Antitumor Vaccines from Tetanus Toxoid Conjugates of MUC1 Glycopeptides with the Thomsen-Friedenreich Antigen and a ...
  http://www.cup.uni-muenchen.de/de/departments/chemie/personen/prof-dr-anja-hoffmann-roeder/
*  KAKEN - Research Projects | Molecular mechanisms for maintenance of the integrity of nervous tissues by glycosphingolipids ...
Presentation] Regulatory mechanisms of malignant phenotypes of human cancers by tumor-associated carbohydrate antigens in the ... Presentation] Involvement of complex carbohydrates in the cancer phenotypes and therapeutic application.2012. *. Author(s). K. ... Presentation] Novel functions and mechanisms of complex carbohydrates elucidated by glycosyltransferase gene knockout2015. *. ... Journal Article] Trimeric Tn antigen on Syndecan-1 binds to integrins and enhances cancer metastasis via dynamic changes of ...
  https://kaken.nii.ac.jp/grant/KAKENHI-PLANNED-23110008/
*  Plus it
Hakomori S. Possible functions of tumour-associated carbohydrate antigens. Curr. Opin. Immunol., 3: 646-653, 1991. ... Ragupathi G. Carbohydrate antigens as targets for active specific immunotherapy. Cancer Immunol. Immunother., 43: 152-157, 1996 ... Selection of tumor antigens as targets for immune attack using immunohistochemistry. I. Focus on gangliosides. Int. J. Cancer, ... We also examined antigen-binding specificity by ganglioside-binding ELISA (12) . The humanized KM8969 reacted strongly with N- ...
  http://cancerres.aacrjournals.org/content/59/20/5323
*  Joint models for longitudinal and time-to-event data: a review of reporting quality with a view to meta-analysis | SpringerLink
Tumor marker carbohydrate antigen 125 predicts adverse outcome after transcatheter aortic valve implantation. JACC Cardiovasc ... Joint modeling tumor burden and time to event data in oncology trials. Pharm Stat. 2014;13(5):286-93.PubMedCrossRefGoogle ... Joint longitudinal and survival-cure models in tumour xenograft experiments. Stat Med. 2014;33(18):3229-40.PubMedCrossRefGoogle ... Synergism between circulating tumor necrosis factor receptor 2 and HbA(1c) in determining renal decline during 5-18 years of ...
  https://link.springer.com/article/10.1186/s12874-016-0272-6
*  Plus it
Hakomori S. Aberrant glycosylation in tumors and tumor-associated carbohydrate antigens. Adv. Cancer Res., 52: 257-331, 1989. ... Among the 10 tumors with low GnT-V expression, 6 tumors had low L-PHA staining, and 2 tumors had moderate L-PHA staining. ... Among the 10 tumors with high GnT-V expression, 6 tumors had high L-PHA staining, and 2 tumors had moderate L-PHA staining. ... The staining pattern of a tumor with high GnT-V expression and high L-PHA staining is shown in A and B. Staining for a tumor ...
  http://clincancerres.aacrjournals.org/content/10/5/1773
*  Identification of Endothelial Cell Surface Carbohydrate-Binding Receptors by Carbohydrate Ligand Mimicry Peptides | Springer...
Substantial evidence suggests that cell surface carbohydrate antigens, particularly those containing fucose residues, are ... Fukuda M (1996) Possible roles of tumor-associated carbohydrate antigens. Cancer Res 56:2237-2244PubMedGoogle Scholar ... Substantial evidence suggests that cell surface carbohydrate antigens, particularly those containing fucose residues, are ... Our study demonstrated the usefulness of carbohydrate-ligand mimicry peptide for the identification of novel carbohydrate- ...
  https://rd.springer.com/chapter/10.1007/978-1-4614-3381-1_5
*  Plus it
Selection of carbohydrate tumor antigens as targets for immune attack using immunotherapy. I. Focus on gangliosides. Int J ... Selection of carbohydrate antigens in human epithelial ovarian cancers as targets for immunotherapy: serous and mucinous tumors ... Selection of tumor antigens as targets for immune attack using immunohistochemistry: protein antigens. Clin Cancer Res 1998;4: ... Selection of tumor antigens as targets for immune attack using immunohistochemistry: II. Blood group related antigens. Int J ...
  http://clincancerres.aacrjournals.org/content/13/14/4170
*  Vaccine Therapy Plus QS21 in Treating Patients With Progressive Prostate Cancer
Vaccines may make the body build an immune response to kill tumor cells. PURPOSE: Phase I trial to study the eff... ... Development of clickable monophosphoryl lipid As towards semi-synthetic conjugates with tumor-associated carbohydrate antigens. ... CD11A ANTIGEN comprises the alpha chain and the CD18 antigen (ANTIGENS, CD18) the beta chain. Lymphocyte function-associated ... Thomsen-Friedenreich antigen (TA) is present on erythrocytes, platelets and glomeruli, and it can be activated du... ...
  https://www.bioportfolio.com/resources/trial/125921/Vaccine-Therapy-Plus-QS21-in-Treating-Patients-With-Progressive-Prostate-Cancer.html
*  ScopeMed.org - Deposit for Medical Articles
Serum Level of Tumor Marker Carbohydrate Antigen-CA125 in Heart Failure. Azra Durak-Nalbantic, Nerma Resic, Mehmed Kulic, ... Metastatic sigmoid tumor treated as primary nasopharyngeal tumor: A case report. Raed Mohammed Aldabbas. Rawal Medical Journal. ...
  http://www.scopemed.org/?term=Anmar%20Raed%20Faris%20Muhaysin&sarea=author&b1=Search+ScopeMed
*  Biosynthesis of Glycoconjugates | Springer for Research & Development
Hakomori, S. I. (1989): Aberrant glycosylation in tumors and tumor-associated carbohydrate antigens. Adv. Cancer. Res. 52, 257- ... Blood Group Rough Endoplasmic Reticulum Carbohydrate Chain Acceptor Substrate Oligosaccharide Chain These keywords were added ...
  https://rd.springer.com/chapter/10.1007/978-3-7091-6294-1_3
*  benign mesothelioma of the pleura 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
MeSH-major] Antigens, Tumor-Associated, Carbohydrate / analysis. Biomarkers, Tumor / analysis. Carcinoma, Non-Small-Cell Lung ... Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antigens, Tumor-Associated, Carbohydrate; 0 / Biomarkers, Tumor; 0 / ... Primary pleural tumors are divided according to their behavior and are discussed separately as benign tumors, tumors of low ... The most common malignant tumor was mesothelioma (85.4%), and solitary fibrous tumor prevailed among benign tumors (9.7%). ...
  http://www.bmlsearch.com/?kwr=benign+mesothelioma+of+the+pleura+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
*  Expression and purification of a novel multi-epitope peptide vaccine for breast cancer immunotherapy - Minerva Biotecnologica...
KEY WORDS: Breast neoplasms - T-lymphocyte epitopes - Tumor-associated carbohydrate antigens - Gene expression - Immunotherapy ... Since the large proportion of BC is due to over-expression of tumor-associated antigens (TAAs), multi-epitope cancer vaccines ... which binds to a natural killer group 2 member D receptor in tumor microenvironment with high affinity and stimulates innate ...
  https://www.minervamedica.it/it/riviste/minerva-biotecnologica/articolo.php?cod=R04Y2017N01A0001
*  Anticancer Agents - Iwao Ojima, Gregory D. Vite, Karl-Heinz Altmann - Oxford University Press
These new and interdisciplinary approaches are aimed at the development of tumor specific anticancer agents while increasing ... 18: Carbohydrate-Based Tumor Antigens as Anti-Tumor Vaccine Agents, Jennifer R. Allen and Samuel J. Danishefsky. 19: Drugs to ... These new and interdisciplinary approaches are aimed at the development of tumor specific anticancer agents while increasing ... 10: Synthesis and Structure-Activity Relationship Studies of Cryptophycins: A Novel Class of Potent Antimitotic Tumor ...
  https://global.oup.com/academic/product/anticancer-agents-9780841237452?lang=en&cc=au