*  Structural glycobiology of antibody recognition in xenotransplantation and cancer immunotherapy
... many tumor-associated carbohydrate antigens are broadly expressed at very high densities on the cell surface of primary and ... Carbohydrate antigens recognized by "natural" or preformed and elicited antibodies are central to transplantation/transfusion ... metastatic tumors, but the same carbohydrates occur at much lower levels and are typically restricted to a few cell types in ... Often the minimal carbohydrate epitopes are located at the terminal end of more complex oligosaccharide chains, which result in ...
  https://espace.curtin.edu.au/handle/20.500.11937/17581
*  Tumor Marker Carbohydrate Antigen 125 Predicts Adverse Outcome After Transcatheter Aortic Valve Implantation - American College...
Tumor Marker Carbohydrate Antigen 125 Predicts Adverse Outcome After Transcatheter Aortic Valve Implantation. May 20, 2013 ... YOU ARE HERE: Home , Latest in Cardiology , Tumor Marker Carbohydrate Antigen 125 Predicts Adverse Outcome After Transcatheter ... What is the predictive value of tumor marker carbohydrate antigen 125 (CA125) before and after transcatheter aortic valve ...
  http://www.acc.org/latest-in-cardiology/journal-scans/2013/05/20/16/03/tumor-marker-carbohydrate-antigen-125-predicts-adverse-outcome
*  Tumor Marker Carbohydrate Antigen 125 Predicts Adverse Outcome After Transcatheter Aortic Valve Implantation | JACC:...
Tumor marker carbohydrate antigen 125 (CA125) is an emerging cardiac biomarker. In heart failure (HF), CA125 has shown to be ... Objectives This study sought to predict the value of tumor marker carbohydrate antigen 125 (CA125) before and after ... Tumor Marker Carbohydrate Antigen 125 Predicts Adverse Outcome After Transcatheter Aortic Valve Implantation ... Tumor Marker Carbohydrate Antigen 125 Predicts Adverse Outcome After Transcatheter Aortic Valve Implantation ...
  http://interventions.onlinejacc.org/content/6/5/487
*  KAKEN - Research Projects | Development of immunotherapy for brain tumors targeting carbohydrate antigens of glycolipids ...
Development of immunotherapy for brain tumors targeting carbohydrate antigens of glycolipids. Research Project ... Publications] T.Yamaki: 'The requirement of host immune response to tumor cells to achieve tumor eradication by intratumoral ... Publications] Yamaki T.: 'The requirement of host immune response to tumor cells to achieve tumor eradication by intratumoral ... Publications] T.Yamaki: 'The requirement of host immune response to tumor cells to achieve tumor eradication by intratumoral ...
  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-05807129/
*  ivd-test-reagent-kits-immunoassay-tumor-marker-carbohydrate-antigen-ca-27.29
Carbohydrate Antigen 27.29) Determination Reagents" , "Reagents, Immunoassay, Tumor Marker, Carbohydrate Antigen CA 27.29" ... IVD Test Reagent/Kits, Immunoassay, Tumor Marker, Carbohydrate Antigen CA 27.29. Definition : Immunoassay reagents intended to ... Home > Specialties > IVD Test Reagent/Kits, Immunoassay, Tumor Marker, Carbohydrate Antigen CA 27.29 ... a carbohydrate-related tumor marker. The detection of the tumor marker CA 27.29 is mostly used in monitoring therapy and ...
  http://www.medicalproductguide.com/term/5559/ivd-test-reagent-kits-immunoassay-tumor-marker-carbohydrate-antigen-ca-27.29
*  ivd-test-reagent-kits-immunoassay-tumor-marker-carbohydrate-antigen-ca-19-9
Carbohydrate Antigen 19-9) Determination Reagents" , "Reagents, Immunoassay, Tumor Marker, Carbohydrate Antigen CA 19-9" ... Home > Specialties > IVD Test Reagent/Kits, Immunoassay, Tumor Marker, Carbohydrate Antigen CA 19-9 ... IVD Test Reagent/Kits, Immunoassay, Tumor Marker, Carbohydrate Antigen CA 19-9. ... a blood-group carbohydrate-related tumor marker. The detection of the tumor marker CA 19-9 is mostly in diagnosis and ...
  http://www.medicalproductguide.com/term/4900/ivd-test-reagent-kits-immunoassay-tumor-marker-carbohydrate-antigen-ca-19-9
*  Oncotarget | Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in...
... a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects ... a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects ... Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast ... Hakomori S. Tumor-associated carbohydrate antigens defining tumor malignancy: basis for development of anti-cancer vaccines. ...
  http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=21959&path%5B%5D=69621
*  Carbohydrates in Drug Design and Discovery (RSC Publishing)
... this book comprehensively covers the new and recent discoveries in the area of carbohydrate drug discovery.Carbohydrates in ... and the use of synthetic ligands based on carbohydrates as drugs has received much attention. Focussing on drug discovery from ... In recent years there has been increasing evidence of the importance of carbohydrates and glycoconjugates in biomedical ... Boosting Humoral Immune Responses to Tumor-associated Carbohydrate Antigens with Virus-like Particles. Zhaojun Yin and Xuefei ...
  http://pubs.rsc.org/en/content/ebook/978-1-84973-939-9
*  Frontiers | Carbohydrate-Mimetic Peptides for Pan Anti-Tumor Responses | Immunology
... consequences of mimicking tumor associated carbohydrate antigens and the notion of reverse engineering to develop carbohydrate ... consequences of mimicking tumor associated carbohydrate antigens and the notion of reverse engineering to develop carbohydrate ... Here, we discuss our experience in bringing a tumor-associated carbohydrate mimetic peptide to the clinic. Emphasis is placed ... Here, we discuss our experience in bringing a tumor-associated carbohydrate mimetic peptide to the clinic. Emphasis is placed ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2014.00308/full
*  Faculty for Chemistry and Pharmacy LMU Munich - Prof. Dr. Anja Hoffmann-Röder
Synthesis of carbohydrates, peptides and glycokonjugates. *Tumor-associated carbohydrate antigens and cancer vaccines ... A. Hoffmann-Röder, J. Schoenhentz, S. Wagner, E. Schmitt, "Perfluoroalkylated amphiphilic MUC1 glycopeptide antigens as tools ... "Synthetic Antitumor Vaccines from Tetanus Toxoid Conjugates of MUC1 Glycopeptides with the Thomsen-Friedenreich Antigen and a ...
  http://www.cup.uni-muenchen.de/de/departments/chemie/personen/prof-dr-anja-hoffmann-roeder/
*  KAKEN - Research Projects | Molecular mechanisms for maintenance of the integrity of nervous tissues by glycosphingolipids ...
Presentation] Regulatory mechanisms of malignant phenotypes of human cancers by tumor-associated carbohydrate antigens in the ... Presentation] Involvement of complex carbohydrates in the cancer phenotypes and therapeutic application.2012. *. Author(s). K. ... Presentation] Novel functions and mechanisms of complex carbohydrates elucidated by glycosyltransferase gene knockout2015. *. ... Journal Article] Trimeric Tn antigen on Syndecan-1 binds to integrins and enhances cancer metastasis via dynamic changes of ...
  https://kaken.nii.ac.jp/grant/KAKENHI-PLANNED-23110008/
*  Plus it
Hakomori S. Possible functions of tumour-associated carbohydrate antigens. Curr. Opin. Immunol., 3: 646-653, 1991. ... Ragupathi G. Carbohydrate antigens as targets for active specific immunotherapy. Cancer Immunol. Immunother., 43: 152-157, 1996 ... Selection of tumor antigens as targets for immune attack using immunohistochemistry. I. Focus on gangliosides. Int. J. Cancer, ... We also examined antigen-binding specificity by ganglioside-binding ELISA (12) . The humanized KM8969 reacted strongly with N- ...
  http://cancerres.aacrjournals.org/content/59/20/5323
*  Plus it
Hakomori S. Aberrant glycosylation in tumors and tumor-associated carbohydrate antigens. Adv. Cancer Res., 52: 257-331, 1989. ... Among the 10 tumors with low GnT-V expression, 6 tumors had low L-PHA staining, and 2 tumors had moderate L-PHA staining. ... Among the 10 tumors with high GnT-V expression, 6 tumors had high L-PHA staining, and 2 tumors had moderate L-PHA staining. ... The staining pattern of a tumor with high GnT-V expression and high L-PHA staining is shown in A and B. Staining for a tumor ...
  http://clincancerres.aacrjournals.org/content/10/5/1773
*  Identification of Endothelial Cell Surface Carbohydrate-Binding Receptors by Carbohydrate Ligand Mimicry Peptides | Springer...
Substantial evidence suggests that cell surface carbohydrate antigens, particularly those containing fucose residues, are ... Fukuda M (1996) Possible roles of tumor-associated carbohydrate antigens. Cancer Res 56:2237-2244PubMedGoogle Scholar ... Substantial evidence suggests that cell surface carbohydrate antigens, particularly those containing fucose residues, are ... Our study demonstrated the usefulness of carbohydrate-ligand mimicry peptide for the identification of novel carbohydrate- ...
  https://rd.springer.com/chapter/10.1007/978-1-4614-3381-1_5
*  Plus it
Selection of carbohydrate tumor antigens as targets for immune attack using immunotherapy. I. Focus on gangliosides. Int J ... Selection of carbohydrate antigens in human epithelial ovarian cancers as targets for immunotherapy: serous and mucinous tumors ... Selection of tumor antigens as targets for immune attack using immunohistochemistry: protein antigens. Clin Cancer Res 1998;4: ... Selection of tumor antigens as targets for immune attack using immunohistochemistry: II. Blood group related antigens. Int J ...
  http://clincancerres.aacrjournals.org/content/13/14/4170
*  Vaccine Therapy Plus QS21 in Treating Patients With Progressive Prostate Cancer
Vaccines may make the body build an immune response to kill tumor cells. PURPOSE: Phase I trial to study the eff... ... Development of clickable monophosphoryl lipid As towards semi-synthetic conjugates with tumor-associated carbohydrate antigens. ... CD11A ANTIGEN comprises the alpha chain and the CD18 antigen (ANTIGENS, CD18) the beta chain. Lymphocyte function-associated ... Thomsen-Friedenreich antigen (TA) is present on erythrocytes, platelets and glomeruli, and it can be activated du... ...
  https://www.bioportfolio.com/resources/trial/125921/Vaccine-Therapy-Plus-QS21-in-Treating-Patients-With-Progressive-Prostate-Cancer.html
*  ScopeMed.org - Deposit for Medical Articles
Serum Level of Tumor Marker Carbohydrate Antigen-CA125 in Heart Failure. Azra Durak-Nalbantic, Nerma Resic, Mehmed Kulic, ... Metastatic sigmoid tumor treated as primary nasopharyngeal tumor: A case report. Raed Mohammed Aldabbas. Rawal Medical Journal. ...
  http://www.scopemed.org/?term=Anmar%20Raed%20Faris%20Muhaysin&sarea=author&b1=Search+ScopeMed
*  Biosynthesis of Glycoconjugates | Springer for Research & Development
Hakomori, S. I. (1989): Aberrant glycosylation in tumors and tumor-associated carbohydrate antigens. Adv. Cancer. Res. 52, 257- ... Blood Group Rough Endoplasmic Reticulum Carbohydrate Chain Acceptor Substrate Oligosaccharide Chain These keywords were added ...
  https://rd.springer.com/chapter/10.1007/978-3-7091-6294-1_3
*  benign mesothelioma of the pleura 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
MeSH-major] Antigens, Tumor-Associated, Carbohydrate / analysis. Biomarkers, Tumor / analysis. Carcinoma, Non-Small-Cell Lung ... Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antigens, Tumor-Associated, Carbohydrate; 0 / Biomarkers, Tumor; 0 / ... Primary pleural tumors are divided according to their behavior and are discussed separately as benign tumors, tumors of low ... The most common malignant tumor was mesothelioma (85.4%), and solitary fibrous tumor prevailed among benign tumors (9.7%). ...
  http://www.bmlsearch.com/?kwr=benign+mesothelioma+of+the+pleura+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
*  Expression and purification of a novel multi-epitope peptide vaccine for breast cancer immunotherapy - Minerva Biotecnologica...
KEY WORDS: Breast neoplasms - T-lymphocyte epitopes - Tumor-associated carbohydrate antigens - Gene expression - Immunotherapy ... Since the large proportion of BC is due to over-expression of tumor-associated antigens (TAAs), multi-epitope cancer vaccines ... which binds to a natural killer group 2 member D receptor in tumor microenvironment with high affinity and stimulates innate ...
  https://www.minervamedica.it/it/riviste/minerva-biotecnologica/articolo.php?cod=R04Y2017N01A0001
*  TIDCs may express diverse phenotypes but are immature i | Open-i
A) DCs were enriched from the indicated solid tumors and analyzed for the expression o ... Antigens, Tumor-Associated, Carbohydrate/immunology*. *CpG Islands/immunology*. *Dendritic Cells/cytology/immunology* ... Bottom Line: Deficient antitumor immunity could be related to a lack of tumor-associated antigen (TAA) presentation by tumor- ... Bottom Line: Deficient antitumor immunity could be related to a lack of tumor-associated antigen (TAA) presentation by tumor- ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2196048_20020732f1&req=4
*  adenocarcinoma endometrial stage iv 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Chemical-registry-number] 0 / Antigens, Tumor-Associated, Carbohydrate; 0 / Biomarkers, Tumor; 0 / CA-125 Antigen; 0 / CA-72-4 ... Chemical-registry-number] 0 / Antigens, Tumor-Associated, Carbohydrate; 0 / Biomarkers, Tumor; 0 / Galectin 1; 0 / Mucin-1; ... MeSH-major] Antigens, Tumor-Associated, Carbohydrate / biosynthesis. Carcinoma, Endometrioid / metabolism. Endometrial ... Hoskins PJ, Le N: Preoperative tumor markers at diagnosis in women with malignant mixed müllerian tumors/carcinosarcoma of the ...
  http://www.bmlsearch.com/?kwr=adenocarcinoma+endometrial+stage+iv+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
*  CA50 - AM09238PU-N | acris-antibodies.com
... a carcinoma associated carbohydrate antigen, has been found to be elevated in the blood of patients with colorectal cancer and ... CA50 has been evaluated in various studies for use as a tumor marker for cancer diagnosis. Results showed that CA50 was ... Cancer antigen 50 (CA50), a carcinoma associated carbohydrate antigen, has been found to be elevated in the blood of patients ... Cancer Antigen 50, Carbohydrate antigen CA50, Tumour marker CA 50. Presentation. Aff - Purified. ...
  https://www.acris-antibodies.com/antibodies/primary-antibodies/ca50-am09238pu-n.htm
*  JournalTOCs
Carcinomas express unique carbohydrates, known as tumor-associated carbohydrate antigens (TACAs), on their surface. These are ... Tumor-Associated Carbohydrate Antigens*Authors: Seyed I. Sadraei; Michael R. Reynolds; John F. Trant. Abstract: Publication ... Source:Advances in Carbohydrate Chemistry and Biochemistry, Volume 70. Author(s): Derek Horton. The field of carbohydrate ... Advances in Carbohydrate Chemistry and Biochemistry. [SJR: 0.9] [H-I: 30] [9 followers] Follow Subscription journal. ISSN ( ...
  https://www.journaltocs.ac.uk/index.php?action=browse&subAction=pub&publisherID=317&journalID=17394&pageb=1&userQueryID=&sort=&local_page=&sorType=&sorCol=
*  Plus it
Hakamori S. Aberrant glycosylation in tumors and tumor-associated carbohydrate antigens. Adv. Cancer Res., 52: 257-331, 1989. ... Polyvalent Vaccines Containing Carbohydrate Antigens.. The carbohydrate Ag Globo H (Fucα1→2Galβ1→3Galα1→4Galβ1→4Glcβl→1Cer) is ... 4 The abbreviations used are: IL, interleukin; NK, natural killer; Ag, antigen; Ab, antibody; TAA, tumor-associated antigen; ... Some proteins are tumor specific, but others, such as the universal tumor Ag hTERT, are broadly expressed by most tumor cells. ...
  http://clincancerres.aacrjournals.org/content/9/9/3222