*  Plus it
Defective maturation and function of antigen-presenting cells in type 1 diabetes. Lancet 1995;345:491-492 ... CD40 engagement by T-cell-expressed CD40 ligand reportedly contributes to DCs subsequently upregulating expression of CD80 and ... levels of MHC class I and II as well as CD80 and CD86 expression were significantly higher on iNKT-conditioned DCs from B6.H2g7 ... H2g7 mice drove higher levels of antigen-stimulated AI4 T-cell proliferation and IFNγ production (Fig. 3A and B). Conversely, ...
  http://diabetes.diabetesjournals.org/content/59/2/423
*  T-lymphocyte activation antigen CD80
The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011 ...
  https://pharos.nih.gov/idg/targets/P33681
*  T Lymphocyte Activation Antigen CD80 Industry, 2018 Market Research Report - News and PR
... is a professional and in-depth study on the current state of the global T Lymphocyte Activation Antigen CD80 industry with a ... Global and Chinese T Lymphocyte Activation Antigen CD80 Industry, 2013-2023 Market Research Report' ... 1.2 Development of T Lymphocyte Activation Antigen CD80 Industry. 1.3 Status of T Lymphocyte Activation Antigen CD80 Industry ... 2.2 Analysis of T Lymphocyte Activation Antigen CD80 Manufacturing Technology. 2.3 Trends of T Lymphocyte Activation Antigen ...
  http://www.newsandpr.com/2018/06/t-lymphocyte-activation-antigen-cd80-industry-2018-market-research-report/
*  CD80 Gene - GeneCards | CD80 Protein | CD80 Antibody
CD80 Molecule, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene ... cDNA FLJ75225, highly similar to Homo sapiens CD80 antigen (CD28 antigen ligand 1, B7-1 antigen) (CD80), mRNA (A0N0P2_HUMAN) ... GeneCards Summary for CD80 Gene CD80 (CD80 Molecule) is a Protein Coding gene. Diseases associated with CD80 include Vaccinia ... P33681-CD80_HUMAN. Recommended name:. T-lymphocyte activation antigen CD80 Protein Accession:. P33681. Secondary Accessions: * ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=CD80
*  Belatacept - DrugBank
... which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, ... CD80. Uniprot ID. P33681. Uniprot Name. T-lymphocyte activation antigen CD80. Molecular Weight. 33047.625 Da. ... UT-lymphocyte activation antigen CD80. Not Available. Human. Absorption. Following multiple intravenous doses of an initial 10 ... Belatacept specifically binds to CD80 and CD86 receptors that are found on the antigen-presenting cell (B cells, macrophages, ...
  https://www.drugbank.ca/drugs/DB06681
*  Abatacept - DrugBank
... which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, ... CD80. Uniprot ID. P33681. Uniprot Name. T-lymphocyte activation antigen CD80. Molecular Weight. 33047.625 Da. ... Ordinarily, full T-cell activation requires binding of the T-cell receptor to an antigen-MHC complex on the antigen-presenting ... by the binding of the CD28 protein on the surface of the T-cell with the CD80/86 proteins on the surface of the antigen- ...
  https://www.drugbank.ca/drugs/DB01281
*  Durvalumab - DrugBank
CD80. Uniprot ID. P33681. Uniprot Name. T-lymphocyte activation antigen CD80. Molecular Weight. 33047.625 Da. ... Durvalumab is a human immunoglobulin G1 kappa (IgGIk) monoclonal antibody that blocks PD-L1 binding to PD-1 and CD80. PD1 ... Most likely to be degraded into peptides and amino acids by circulating phagocytic cellsor by target antigen-containing cells [ ... The therapeutic efficacy of Bacillus calmette-guerin substrain tice live antigen can be decreased when used in combination with ...
  https://www.drugbank.ca/drugs/DB11714
*  T lymphocyte co-signaling pathways of the B7-CD28 family.
0/Antigens, CD; 0/Antigens, CD28; 0/Antigens, CD80; 0/Antigens, CD86; 0/Antigens, Differentiation; 0/Antigens, Differentiation ... Antigens, CD. Antigens, CD28 / immunology*. Antigens, CD80 / immunology*. Antigens, CD86 / immunology*. Antigens, ... Antigens, Differentiation, T-Lymphocyte / immunology. Humans. Lymphocyte Activation. Receptors, Immunologic / immunology. ... T-Lymphocyte; 0/BTLA protein, human; 0/Receptors, Immunologic; 0/cytotoxic T-lymphocyte antigen 4; 0/inducible T-cell co- ...
  http://www.biomedsearch.com/nih/T-lymphocyte-co-signaling-pathways/16212919.html
*  Primary and Metastatic Uveal Melanoma Cells Genetically Modified to Express HLA-DR and CD80 Present Class II Restricted Tumor...
Conclusions: : Therefore, HLA-DR+/CD80+ uveal melanoma cells activate Th cells to endogenous antigens, and could be used in ... As measured by flow cytometry, HLA-DRB*0101 and CD80 transduced uveal melanoma cells express HLA-DR1 and CD80 on the cell ... restricted tumor antigens is difficult due to the inhibition of Antigen Presenting Cells (APC) within the tumor environment and ... HER2/neu-expressing primary and metastatic uveal melanoma transductants MEL202/DR1/CD80 and OMM2.3/DR1/CD80 were co-cultured as ...
  http://iovs.arvojournals.org/article.aspx?articleid=2394950
*  Anti-CD80 antibody (PE/Cy5®) [2D10.4] | Abcam
Anti-CD80 antibody conjugated to PE/Cy5® [2D10.4] validated for Flow Cyt and tested in Human. Referenced in 1 publication. ... CD80 antigen (CD28 antigen ligand 1, B7-1 antigen) antibody. *CD80 antigen antibody ... Anti-CD80 antibody [2D10.4], prediluted (PE/Cy5®). See all CD80 primary antibodies. ... Flow Cytometric analysis of normal Human peripheral blood cells labeling CD80 with ab155374 (filled histogram) at 1 µg/test in ...
  https://www.abcam.com/cd80-antibody-2d104-prediluted-pecy5-ab155374.html
*  Split responses of the F5 transgenic T cells to peptid | Open-i
It has been proposed that some bystander T cell activation may in fact be due to T cell antigen receptor (TCR) cross-reactivity ... It has been proposed that some bystander T cell activation may in fact be due to T cell antigen receptor (TCR) cross-reactivity ... The proliferation is specific, as control peptide from a tumor antigen P1A, which binds H-2Ld but not Db, induces no ... The proliferation is specific, as control peptide from a tumor antigen P1A, which binds H-2Ld but not Db, induces no ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2199130_JEM.971488f1a&req=4
*  Extract of Oregano, Coffee, Thyme, Clove, and Walnuts Inhibits NF-κB in Monocytes and in Transgenic Reporter Mice | Cancer...
4C, Ccl3), Cd80 antigen (Fig. 4D, CD80), Cd40 antigen (Fig. 4E, CD40), chemokine ligand 10 (Fig. 4G, Cxcl10), chemokine ligand ... Ccl3, chemokine ligand 3; Cd80, CD80 antigen; Cd40, CD40 antigen; Csf1, colony stimulating factor 1 (macrophage); Cxcl10, ... Cd80, Cd40, Il2ra, and Ptprc), growth factor (Csf1), cell adhesion molecule (Vcam1), enzymes (Hmox1 and Nos2), and mitogen ( ...
  http://cancerpreventionresearch.aacrjournals.org/content/3/5/653.full
*  B7-DC and anti-CD28 mAb synergize for costimulation of | Open-i
Antigens, CD/physiology*. *Antigens, CD80/physiology*. *Antigens, Surface/physiology*. *CD4-Positive T-Lymphocytes/immunology* ... Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptor. ... Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptor. ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2196092_20030242f5b&req=4
*  Systemic sHIgM12 treatment increases the number of adop | Open-i
B7-DC molecules are known to function as ligands on antigen-presenting cells (APCs), enhancing T cell activation. In this study ... B7-DC molecules are known to function as ligands on antigen-presenting cells (APCs), enhancing T cell activation. In this study ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2193990_20021466f4&req=4
*  TIMBAL
CD80_MOUSE. T-lymphocyte activation antigen CD80 (Activation B7-1 antigen) (B7) (CD antigen CD80). Cd80 B7. Mus musculus (Mouse ... CD80_RABIT. T-lymphocyte activation antigen CD80 (Activation B7-1 antigen) (CD antigen CD80). CD80. Oryctolagus cuniculus ( ... T-lymphocyte activation antigen CD80 (Activation B7-1 antigen) (BB1) (CTLA-4 counter-receptor B7.1) (B7) (CD antigen CD80). ... CD80 (B7-1). T-lymphocyte activation antigen cd80 (activation b7-1 antigen). ...
  http://mordred.bioc.cam.ac.uk/timbal/CD80%20
*  CD80 transfected human hepatocellular carcinoma cells activate cytotoxic T lymphocytes to target HCC cells with shared tumor...
... human hepatocellular carcinoma cells activate cytotoxic T lymphocytes to target HCC cells with shared tumor antigens ... CD80 transfected human hepatocellular carcinoma cells activate cytotoxic T lymphocytes to target HCC cells with shared tumor ...
  http://cell-lines.toku-e.com/Reference_194.html
*  Co-stimulatory | definition of Co-stimulatory by Medical dictionary
T-cell surface specific glycoprotein CD28 with T-cell activation antigens CD80 and CD86 that are expressed on antigen ... Immunology The delivery of a 2nd signal from an antigen-presenting cell to a T cell, which rescues an activated T cell from ... B cells require a co-stimulatory signal together with antigen recognition for B cell activation.. Negative regulation of B cell ... Engagement of T cells requires two signals: antigen recognition through the T cell receptor (TCR) and major histocompatibility ...
  http://medical-dictionary.thefreedictionary.com/Co-stimulatory
*  Role of Oxidative Stress in Estrogen-related Bone Loss Discovered by Boffins
... that processes and presents antigen material on the surface of other immune cells D to up-regulate the immune antigen CD80. ... CD80 is a 'co-stimulatory' molecule that is part of the CD80/CD28 pathway required for activation of T lymphocytes. When this ... They found that reactive oxygen stimulates dendritic cells D a type of 'antigen-presenting cell' ... which prevents the activation of T cells by blocking the binding of CD80 to CD28. Because CTLA4-Ig did not directly affect ...
  http://www.medindia.net/news/Role-of-Oxidative-Stress-in-Estrogen-related-Bone-Loss-Discovered-by-Boffins-26269-1.htm
*  Increased expression of TLRs in mDCs and pDCs of dengue | Open-i
Methodology/principal findings: We evaluated the expression levels of TLR2, 3, 4 and 9 and the co-stimulatory molecules CD80 ... Furthermore, the expression of CD80 and CD86 was altered in mDCs and CD86 in pDCs of severe dengue cases. We show that ... Methodology/principal findings: We evaluated the expression levels of TLR2, 3, 4 and 9 and the co-stimulatory molecules CD80 ... Furthermore, the expression of CD80 and CD86 was altered in mDCs and CD86 in pDCs of severe dengue cases. We show that ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3585035_pntd.0002060.g003&req=4
*  Strong increase of protective serum cytokines after inj | Open-i
Antigens, CD274. *Antigens, CD80/metabolism. *Antigens, Surface/metabolism. *Apoptosis Regulatory Proteins/metabolism ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2875405_pone.0010800.g005&req=4
*  Only TCR-CD28-stimulated DP thymocytes die in respons | Open-i
Antigen Presentation. *Antigens, CD/genetics. *Antigens, CD80/physiology. *Antigens, CD95/genetics/physiology ... by TCR signals in the absence of simultaneous costimulatory signals and is mediated by subsequent interaction with antigen- ... by TCR signals in the absence of simultaneous costimulatory signals and is mediated by subsequent interaction with antigen- ... strategies that are differentially implemented during development depending on whether immature thymocytes encounter antigen in ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2199155_JEM.971308f3d&req=4
*  Estimating the kon and koff for sCD80 binding CTLA-4 Ig | Open-i
... on antigen-presenting cells (APC) and modulate T cell antigen recognition. Preliminary reports have suggested that CD80 binds ... on antigen-presenting cells (APC) and modulate T cell antigen recognition. Preliminary reports have suggested that CD80 binds ... CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics. ... In the present study, we use surface plasmon resonance to measure the affinity and kinetics of CD80 binding to CD28 and CTLA-4 ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2196039_JEM.vandermerwe4&req=4
*  Induction of IFN-γ- and TNF-α-secreting CD8+ T cell s | Open-i
Antigens, CD/biosynthesis. *Antigens, CD80/biosynthesis. *Cross-Priming/immunology. *Female. *Humans. *Immunoglobulins/ ... leading to the subsequent presentation of bacterial antigens and triggering the induction of memory T cells, mostly CD3(+)CD8 ... leading to the subsequent presentation of bacterial antigens and triggering the induction of memory T cells, mostly CD3(+)CD8 ... leading to the subsequent presentation of bacterial antigens and triggering the induction of memory T cells, mostly CD3(+)CD8 ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2691582_pone.0005879.g009&req=4
*  B7-DC costimulates PD1−/− CD4+ T cells. (a) Purifie | Open-i
Antigens, CD/physiology*. *Antigens, CD80/physiology*. *Antigens, Surface/physiology*. *CD4-Positive T-Lymphocytes/immunology* ... Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptor. ... Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptor. ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2196092_20030242f4&req=4
*  Percentage of TFH and expression of CXCR5 and PD-1 duri | Open-i
Antigens, CD80/metabolism. *Antigens, CD86/metabolism. *Female. *Fingolimod Hydrochloride. *Follow-Up Studies ... Methods: Using flow cytometry, B and T cell subtypes, and their expression of antigen presentation, costimulation and migration ... Methods: Using flow cytometry, B and T cell subtypes, and their expression of antigen presentation, costimulation and migration ... Furthermore, expression of surface molecules involved in antigen presentation and costimulation during fingolimod treatment are ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4215872_pone.0111115.g004&req=4