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*  Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein. | Scholars...
Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein.'s profile, ... In contrast, CD4 had no effect on the release of HIV-1 bearing a heterologous envelope protein unable to bind CD4. Nef ... RESULTS: Using human 293T cells expressing high levels of cell-surface CD4 or CD8, we demonstrate that CD4, but not CD8, can ... Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein. Journal ...
  https://scholars.duke.edu/display/pub647919
*  CD4 Antigens - CD4 Antigen Summary Report | CureHunter
55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. CD4 antigens are members of ... CD4 antigens also serve as INTERLEUKIN-15 receptors and bind to the HIV receptors, binding directly to the HIV ENVELOPE PROTEIN ... CD4 Antigen; Receptors, CD4; Antigens, CD4; Receptors, Surface CD4; Surface CD4 Receptor; Antigen, CD4; Antigens, T-Cell T4; ... CD4 Antigens (CD4 Antigen). Subscribe to New Research on CD4 Antigens 55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and ...
  http://www.curehunter.com/public/keywordSummaryD015704-CD4-Antigens-CD4-Antigen.do
*  Human antigen-specific CD4⁺ CD25⁺ CD134⁺ CD39⁺ T cells are enriched for regulatory T cells and comprise a substantial...
Human antigen-specific CD4⁺ CD25⁺ CD134⁺ CD39⁺ T cells are enriched for regulatory T cells and comprise a substantial ... Human Ag-specific CD4(+) Txa0cells can be detected by their dual expression of CD134 (OX40) and CD25 after a 44 hours ... We show that surface expression of CD39 on Ag-specific cells consistently identifies a substantial population of CD4(+) CD25 ... Collectively, our data show that Ag-specific CD4(+) CD25(+) CD134(+) CD39(+) Txa0cells are highly enriched for Treg cells, form ...
  https://www.sigmaaldrich.com/catalog/papers/24752698
*  Gereke, M., Jung, S., Buer, J. and Bruder, D. (2009) Alveolar type II epithelial cells present antigen to CD4(1) T cells and...
Alveolar type II epithelial cells present antigen to CD4(1) T cells and induce Foxp3(1) regula-tory T cells. American Journal ... Gereke, M., Jung, S., Buer, J. and Bruder, D. (2009) Alveolar type II epithelial cells present antigen to CD4(1) T cells and ... Human CD4- CD8- Invariant Natural Killer T Cells Promote IgG Secretion from B Cells Stimulated by Cross-Linking of Their ... Innate-like CD4 T cells selected by thymocytes suppress adaptive immune responses against bacterial infections ...
  http://www.scirp.org/reference/ReferencesPapers.aspx?ReferenceID=730672
*  CD4 antigen | Article about CD4 antigen by The Free Dictionary
Although all animals have... Explanation of CD4 antigen ... Find out information about CD4 antigen. see immunity immunity, ... redirected from CD4 antigen). Also found in: Dictionary, Thesaurus, Medical.. Related to CD4 antigen: CD4+ cell antigen:. see ... CD4 antigen , Article about CD4 antigen by The Free Dictionary https://encyclopedia2.thefreedictionary.com/CD4+antigen ... the somatic or O antigens), or from the flagella (the flagellar or H antigens). Other antigens either are excreted by the cell ...
  http://encyclopedia2.thefreedictionary.com/CD4+antigen
*  Concordance of human leukocyte antigen haplotype-sharing, CD4 decline and AIDS in hemophilic siblings. Multicenter Hemophilia...
... haplotypes and the incidence rates of CD4 decline to , 20% and to AIDS. DESIGN: Retrospective cohort study of 95 HIV-1-infected ... To assess the association between human leukocyte antigen (HLA) ... Concordance of human leukocyte antigen haplotype-sharing, CD4 ... OBJECTIVE: To assess the association between human leukocyte antigen (HLA) haplotypes and the incidence rates of CD4 decline to ... Concordance of human leukocyte antigen haplotype-sharing, CD4 decline and AIDS in hemophilic siblings. Multicenter Hemophilia ...
  https://www.rti.org/publication/concordance-human-leukocyte-antigen-haplotype-sharing-cd4-decline-and-aids-hemophilic-0
*  Acquisition of an additional antigen specificity after mouse CD4 gene transfer into a T helper hybridoma. | JEM
Acquisition of an additional antigen specificity after mouse CD4 gene transfer into a T helper hybridoma.. W G Ballhausen, A B ... These experiments suggest that CD4 may be important in determining the antigen fine specificity and, therefore, may also play a ... Acquisition of an additional antigen specificity after mouse CD4 gene transfer into a T helper hybridoma. ... We have transfected the mouse CD4 gene into a beef insulin (BI)-specific murine T helper hybridoma that lacks CD4 surface ...
  http://jem.rupress.org/content/167/4/1493
*  Lirias: Antigen recognition by autoreactive CD4⁺ thymocytes drives homeostasis of the thymic medulla
Antigen recognition by autoreactive CD4⁺ thymocytes drives homeostasis of the thymic medulla. ... This process exhibits strict dependence on TCR-reactivity with self-antigens expressed by mTECs, as well as engagement of the ... We demonstrate here that conventional SP CD4⁺ thymocytes bearing autoreactive TCRs drive a homeostatic process that fine-tunes ... These interactions induce the expression of lymphotoxin α in autoreactive CD4⁺ thymocytes and RANK in mTECs. Lymphotoxin in ...
  https://lirias.kuleuven.be/handle/123456789/432787
*  Assessment of immunosuppressive activity of human mesenchymal stem cells using murine antigen specific CD4 and CD8 T cells in...
Murine clonal CD4 and CD8 T cells were stimulated with cognate peptide antigen and antigen presenting cells (APCs) in the ... Human MSCs (hMSCs) can alter multiple aspects of murine T cell activation induced by stimulation with specific antigen, ... hMSCs inhibit antigen-induced murine T-cell proliferation. A total of 2 × 106 purified antigen specific murine CD4+(A) and CD8+ ... Murine clonal CD4 and CD8 T cells were stimulated with cognate peptide antigen and antigen presenting cells (APCs) in the ...
  https://stemcellres.biomedcentral.com/articles/10.1186/scrt339
*  Distinct Pathways of Antigen Uptake and Intracellular Routing in CD4 and CD8 T Cell Activation | Science
Distinct Pathways of Antigen Uptake and Intracellular Routing in CD4 and CD8 T Cell Activation ... Distinct Pathways of Antigen Uptake and Intracellular Routing in CD4 and CD8 T Cell Activation ... Distinct Pathways of Antigen Uptake and Intracellular Routing in CD4 and CD8 T Cell Activation ... Distinct Pathways of Antigen Uptake and Intracellular Routing in CD4 and CD8 T Cell Activation ...
  http://science.sciencemag.org/content/316/5824/612
*  Psoriatic arthritis joint fluids are characterized by CD8 and CD4 T cell clonal expansions appear antigen driven. - PubMed -...
Psoriatic arthritis joint fluids are characterized by CD8 and CD4 T cell clonal expansions appear antigen driven.. Costello PJ1 ... The CD4 T cell joint fluid repertoire contained fewer and smaller oligoclonal expansions also largely restricted to the joint, ... suggesting that CD4 T cells participate perhaps by interacting cognitively to generate the CD8 clones. The inferred amino acid ... driven intra-articular CD4, and CD8 T cell clonal expansions. ... CD4-Positive T-Lymphocytes/immunology*. *CD4-Positive T- ...
  https://www.ncbi.nlm.nih.gov/pubmed/11160357
*  Abstract: Caspase-3 on patient antigen-specific CD4<sup>+</sup> T cells diagnose active tuberculosis and monitor treatment...
Caspase-3 on patient antigen-specific CD4+ T cells diagnose active tuberculosis and monitor treatment response ... Methods: Using polychromatic flow cytometry, we evaluated the expression of active caspase-3 on Mtb-specific CD4+ T cells from ... Results: Frequencies of Mtb-specific IFN-g+CD4+ T cells that expressed active caspase-3 were substantially higher in subjects ... Conclusion: We have identified a host blood-based biomarker on Mtb-specific CD4+ T cells that discriminate between ATB and LTBI ...
  https://idsa.confex.com/idsa/2015/webprogram/Paper53409.html
*  Human keratinocyte induction of rapid effector function in antigen-specific memory CD4|sup|+|/sup|and CD8|sup|+|/sup|T cells -...
These findings demonstrate that keratinocytes are able to efficiently process and present antigen to CD4+and CD8+memory T cells ... Keratinocytes were able to efficiently process and present protein antigen to CD4+T cells, resulting in cytokine secretion (Th1 ... Furthermore, it is unclear whether keratinocytes can process antigen prior to MHC class I and class II presentation. We tested ... protein and recombinant expression vectors as sources of antigen. ...
  https://www.phc.ox.ac.uk/publications/10474
*  Frontiers | Correlates of Follicular Helper Bias in the CD4 T Cell Response to a Retroviral Antigen | Immunology
Conversely, the response to the same antigen, presented in different immunisation regimens, elicited a response typically ... Conversely, the response to the same antigen, presented in different immunisation regimens, elicited a response typically ... differentiation of CD4+ T cells reactive with a retroviral envelope glycoprotein model antigen, presented in its natural ... differentiation of CD4+ T cells reactive with a retroviral envelope glycoprotein model antigen, presented in its natural ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2018.01260/full
*  The HIV-1 gp120/V3 modifies the response of uninfected CD4 T cells to antigen presentation: mapping of the specific...
We have previously demonstrated that the presence of specific gp120/V3 peptides during antigen presentation can modify the ... proliferation and antigen presentation. Canonical pathways involved in energy and cell cycle regulation, and in the co- ... study was to map the specific transcriptional profile invoked by an HIV-1/V3 epitope in uninfected T cells during antigen ... peripheral blood monocytes to V3 lipopeptides using a liposome delivery system followed by a superantigen-mediated antigen ...
  https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-9-160
*  eCite - Dasatinib inhibits recombinant viral antigen-specific murine CD4(+) and CD8(+) T-cell responses and NK-cell cytolytic...
Dasatinib inhibits recombinant viral antigen-specific murine CD4(+) and CD8(+) T-cell responses and NK-cell cytolytic activity ... Dasatinib inhibits recombinant viral antigen-specific murine CD4(+) and CD8(+) T-cell responses and NK-cell cytolytic activity ... Dasatinib inhibits recombinant viral antigen-specific murine CD4(+) and CD8(+) T-cell responses and NK-cell cytolytic activity ... Results: Dasatinib inhibited antigen-specific proliferation of murine CD4+ and CD8+ transgenic T cells in vitro and in vivo. ...
  http://ecite.utas.edu.au/63279
*  Antigen-driven CD4+T cell and HIV-1 dynamics: Residual viral replication under highly active antiretroviral therapy - Oxford...
Antigen-driven CD4+T cell and HIV-1 dynamics: Residual viral replication under highly active antiretroviral therapy ... Antigen-driven CD4+T cell and HIV-1 dynamics: Residual viral replication under highly active antiretroviral therapy ...
  https://www.bdi.ox.ac.uk/publications/634357
*  Reactome | Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane]
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Mus musculus) ... Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Mus musculus) ... Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Mus musculus) ... Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Mus musculus) ...
  https://reactome.org/content/detail/R-MMU-202266
*  Epitopes described in Understanding the focused CD4 T cell response to antigen and pathogenic organisms. - Immune Epitope...
Free resource for searching and exporting immune epitopes. Includes more than 95% of all published infectious disease, allergy, autoimmune, and transplant epitope data.
  http://www.iedb.org/pmId/19198764
*  Gentaur Molecular :GenWay \ CD4 - MONOCLONAL ANTIBODY TO RAT CD4; Heat stable antigen; HSA; Nectadrin Monoclonal \ 20-321-175226
CD4 - MONOCLONAL ANTIBODY TO RAT CD4; Heat stable antigen; HSA; Nectadrin Monoclonal \ 20-321-175226 for more molecular ... Heat stable antigen; HSA; Nectadrin Monoclonal. Related products : CD4 - MONOCLONAL ANTIBODY TO RAT CD4; Heat stable antigen; ... CD4 - MONOCLONAL ANTIBODY TO RAT CD4; Heat stable antigen; HSA; Nectadrin Monoclonal antibody storage GENTAUR recommends for ... Product name : CD4 - MONOCLONAL ANTIBODY TO RAT CD4; Heat stable antigen; HSA; Nectadrin Monoclonal ...
  http://www.antibody-antibodies.com/product1898705-search-CD4%20_%20MONOCLONAL%20ANTIBODY%20TO%20RAT%20CD4
*  HIV-1 p24 antigen is a significant inverse correlate of CD4 T-cell change in patients with suppressed viremia under long-term...
HIV-1 p24 antigen is a significant inverse correlate of CD4 T-cell change in patients with suppressed viremia under long-term ... Comparison of p24 antigen and HIV-1 RNA concentrations indicate that the p24 antigen detected in these samples is not ... Comparison of p24 antigen and HIV-1 RNA concentrations indicate that the p24 antigen detected in these samples is not ... the level of p24 antigen as expressed by the absorbance/cutoff ratio was a significant inverse correlate of both the CD4 count ...
  http://www.zora.uzh.ch/id/eprint/2140/
*  Analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- alpha/beta T cells demonstrates...
Analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- alpha/beta T cells demonstrates ... Analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- alpha/beta T cells demonstrates ... To investigate whether these cells are selected to recognize particular antigens or antigen-presenting molecules, DN alpha/beta ... recognize a limited spectrum of antigens and suggests that they may use nonpolymorphic antigen-presenting molecules. ...
  http://jem.rupress.org/content/178/1/1?ijkey=3d3c66f3aaa3a1866ed075c5ecb0f54bd1c81b32&keytype2=tf_ipsecsha
*  Self-Tolerance Checkpoints in CD4 T Cells Specific for a Peptide Derived from the B Cell Antigen Receptor | The Journal of...
DN (CD4− CD8− double negative), DP (CD4+ CD8+ double positive), and CD4 SP (single positive). **p = 0.0023, ***p , 0.0001. ... In these chimeras, WT CD4 SP thymocytes demonstrated an advantage over CA30 CD4 SP thymocytes (∼29% of the CD4 SP thymocytes ... A, CD4+ and CD4− populations of CA30 T cells in the periphery of mixed BM chimeras generated with κTg BM or control B6AF1 BM. ... Briefly, purified CA30 CD4+ naive T cells were labeled with CFSE, and 5 × 103 of these cells were incubated with CD4+ CD25+ ...
  http://www.jimmunol.org/content/187/1/82
*  Gentaur Molecular :GenWay \ CD4 - Mouse monoclonal [Q4120] to CD4; T-cell surface antigen T4 Leu-3 Monoclonal \ 20-272-190839
... to CD4; T-cell surface antigen T4_Leu-3 Monoclonal \ 20-272-190839 for more molecular products just contact us ... CD4 - Mouse monoclonal [Q4120] to CD4; T-cell surface antigen T4_Leu-3 Monoclonal mus musculus murine CD4 - Mouse monoclonal [ ... to CD4; T-cell surface antigen T4_Leu-3 Monoclonal. Related products : CD4 - Mouse monoclonal [Q4120] to CD4; T-cell surface ... to CD4; T-cell surface antigen T4_Leu-3 Monoclonal / Product Detail : 20-272-190839 CD4 - Mouse monoclonal [Q4120] to CD4; T- ...
  http://www.antibody-antibodies.com/product1899625-search-CD4%20_%20Mouse%20monoclonal%20%5BQ4120%5D%20to%20CD4
*  Table of Contents - November 28, 1986, 234 (4780) | Science
Epitopes of the CD4 antigen and HIV infection. By QJ Sattentau, AG Dalgleish, RA Weiss, PC Beverley ... Alterations in T4 (CD4) protein and mRNA synthesis in cells infected with HIV ...
  http://science.sciencemag.org/content/234/4780