*  Expression of a functional CD3-Ti antigen/MHC receptor in the absence of surface CD2. Analysis with clonal Jurkat cell mutants....
Expression of a functional CD3-Ti antigen/MHC receptor in the absence of surface CD2. Analysis with clonal Jurkat cell mutants. ... Expression of a functional CD3-Ti antigen/MHC receptor in the absence of surface CD2. Analysis with clonal Jurkat cell mutants. ... To investigate the requirement for CD2 expression in activation of T lymphocytes via the CD3-Ti antigen/MHC receptor complex, ... In contrast, triggering of their CD3-Ti components resulted in the normal set of T lymphocyte-associated activation events, ...
  http://jem.rupress.org/content/168/6/2077
*  Gentaur Molecular :FabGennix \ CD3, Antigen blocking peptide \ P-CD3-130
CD3, Antigen blocking peptide \ P-CD3-130 for more molecular products just contact us ... CD3 antigen gamma polypeptide (CD3 antigen, gamma polypeptide, isoform CRA_b). [CD3 gamma] T-cell surface glycoprotein CD3 ... We have also other products like : CD3, Antigen blocking peptide Related products : CD3, Antigen blocking peptide ... CD3E T3E] T-cell surface glycoprotein CD3 epsilon chain (T-cell surface antigen T3/Leu-4 epsilon chain) (CD antigen CD3e). [ ...
  http://www.antibody-antibodies.com/product_det.php?id=3097426&supplier=search&name=CD3,%20Antigen%20blocking%20peptide%20
*  The T Cell Marker, CD3 Antigen and Antibodies Mini-review | Bio-Rad
This mini-review explains the structure of CD3, the genes involved in its expression, its function and the signal transduction ... CD3 is an essential T cell co-receptorand defines T cell lineage. CD3is therefore an ideal T cell marker. ... CD3-12 which has a very broad species cross-reactivity for the CD3 marker (Jones et al. 1993). Both CD3 γ and CD3 δ are ... The cytoplasmic segments of CD3 ε, CD3 γ and CD3 δ contain a single ITAM, whereas the cytoplasmic domain of the CD3 ζ subunit ...
  https://www.bio-rad-antibodies.com/minireview-cd3-antibody.html
*  The effect of artificial antigen-presenting cells with preclustered anti-CD28/-CD3/-LFA-1 monoclonal antibodies on the...
Design and Methods Our artificial antigen-presenting cells were generated with activating (anti-CD3), co-stimulating (anti-CD28 ... The activity of our artificial antigen-presenting cells was compared with that of anti-CD3/-CD28 coated immunomagnetic ... The effect of artificial antigen-presenting cells with preclustered anti-CD28/-CD3/-LFA-1 monoclonal antibodies on the ... The effect of artificial antigen-presenting cells with preclustered anti-CD28/-CD3/-LFA-1 monoclonal antibodies on the ...
  http://www.haematologica.org/content/93/10/1523
*  A novel model for antigen-dependent activation of normal human T cells. Transmembrane signaling by crosslinkage of the CD3/T...
Transmembrane signaling by crosslinkage of the CD3/T cell receptor-alpha/beta complex with the cluster determinant 2 antigen.. ... A novel model for antigen-dependent activation of normal human T cells. Transmembrane signaling by crosslinkage of the CD3/T ... and not independent crosslinking of TCR and of CD2 antigen or crosslinking of either protein with the CD4 or CD8 antigen ... suggest that the CD2 antigen might be targeted for the regulation of antigen-specific T cell immunity (e.g., organ ...
  http://jem.rupress.org/content/171/6/1965
*  A novel model for antigen-dependent activation of normal human T cells. Transmembrane signaling by crosslinkage of the CD3/T...
A novel model for antigen-dependent activation of normal human T cells. Transmembrane signaling by crosslinkage of the CD3/T ... and not independent crosslinking of TCR and of CD2 antigen or crosslinking of either protein with the CD4 or CD8 antigen ... suggest that the CD2 antigen might be targeted for the regulation of antigen-specific T cell immunity (e.g., organ ... Antigen presentation. FASEB J. 1989 Nov;3(13):2496-2502. [PubMed]. *Meuer SC, Acuto O, Hussey RE, Hodgdon JC, Fitzgerald KA, ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2187964/?lang=en-ca
*  Macrophage subtypes in symptomatic carotid artery and femoral artery plaques.
0/Antigens, CD; 0/Antigens, CD3; 0/Antigens, Differentiation, Myelomonocytic; 0/Biological Markers; 0/CD68 antigen, human ... Antigens, CD / analysis. Antigens, CD3 / analysis. Antigens, Differentiation, Myelomonocytic / analysis. Atherosclerosis / ... Macrophages and T cell numbers were detected in plaque sections by immunohistochemistry and anti CD68 and CD3 antibodies. Dual ...
  http://www.biomedsearch.com/nih/Macrophage-Subtypes-in-Symptomatic-Carotid/22975154.html
*  Patent US7507873 - Transgenic avians containing recombinant ovomucoid promoters - Google Patents
wherein the therapeutic protein is selected from the group consisting of marine MAb directed against t-lymphocyte antigen CD3, ... wherein the therapeutic protein is selected from the group consisting of murine MAb, directed against t-lymphocyte antigen CD3 ... Antibody was captured from the egg white in microplate wells coated with the antibodies target antigen. Antigen-antibody ... the antigen specific hMab produced by mammalian cells (11A and 11B), the antigen specific hMab produced by a transgenic hen (11 ...
  http://www.google.com/patents/US7507873?dq=5920316
*  Catumaxomab - Wikipedia
It binds to antigens CD3 and EpCAM. It is in clinical trials in the United States currently and is used in Europe. It was ... By binding to such a cell via one arm, to a T lymphocyte via the other arm and to an antigen-presenting cell like a macrophage ... of an anti-EpCAM antibody and one half of an anti-CD3 antibody, so that each molecule of catumaxomab can bind both EpCAM and ... CD3. In addition, the Fc-region can bind to an Fc receptor on accessory cells like other antibodies, which has led to calling ...
  https://en.wikipedia.org/wiki/Catumaxomab
*  Measurement of T Cell Activation After 16‐hr In Vitro Stimulation with Concanavalin A - Current Protocols
Fluorochrome‐conjugated monoclonal antibodies that recognize cell surface antigens CD3, CD4, CD8, and CD69 (Table 6.28.1. ): * ... CD3. PerCP. CD3 versus side scatter, gate on lymphocytes, count 30,000. CD4. APC. CD69 versus CD4, count CD69+ and CD69- CD4 ... CD8 FITC, CD69 PE, and CD3 PerCP antibodies (e.g., FastImmune CD8 FITC, CD69 PE and CD3 PerCP antibody mix, BD Bioscience, ... Induction of CD69 antigen on normal CD4+ and CD8+ lymphocyte subsets and its relationship with the phenotype of responding T‐ ...
  http://www.currentprotocols.com/WileyCDA/CPUnit/refId-cy0628.html?quicktabs_cp=materials
*  Cd3d - PrimePCR Assay and Template | Life Science | Bio-Rad
CD3 antigen, delta polypeptide Assay Type: EvaGreen Application: Gene Expression Unique Assay ID: dMmuEG5073499 Info: EG; Same ... CD3 antigen, delta polypeptide Assay Type: Probe Application: Gene Expression Unique Assay ID: dMmuCPE5110222 Info: FAM; Same ... CD3 antigen, delta polypeptide Assay Type: Probe Application: Gene Expression Unique Assay ID: dMmuCPE5110223 Info: HEX; Same ... CD3 antigen, delta polypeptide Assay Type: Probe Assay Design: Intron-spanning Application: Gene Expression Unique Assay ID: ...
  http://www.bio-rad.com/en-us/prime-pcr-assays/gene/cd3d-mouse
*  Transient Inhibition of Interleukin 4 Signaling by T Cell Receptor Ligation | JEM
Both soluble anti-CD3/anti-CD28 and antigen treatment of T cells inhibit IL-4 signaling. BALB/c lymph node cells and spleen ... Soluble Anti-CD3 or Antigen Also Inhibits IL-4-mediated Signaling.. To determine whether more physiologic modes of TCR ... For the signaling experiments using soluble anti-CD3 or antigen, lymph node and spleen cells from BALB/c mice or lymph node ... we tested the effect of soluble anti-CD3 or of antigen in the presence of APCs. ...
  http://jem.rupress.org/content/192/8/1125
*  Treatment with polyclonal antilymphocyte globulins indu | Open-i
Treatment with polyclonal antilymphocyte globulins induces depletion of circulating CD3+CD4+CD28− T-cells in transplant ... Antigens, CD3. *Antigens, CD95/metabolism. *Caspases/metabolism. *Cytokines/biosynthesis. *Down-Regulation/drug effects ... Bottom Line: In vivo, peripheral levels of CD3(+)CD4(+)CD28(-) T-cells decreased from 3.7 ± 7.1% before to 0 ± 0% six hours ... Bottom Line: In vivo, peripheral levels of CD3(+)CD4(+)CD28(-) T-cells decreased from 3.7 ± 7.1% before to 0 ± 0% six hours ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3316508_pone.0033939.g001&req=4
*  CD56+CD3− lymphocytes express CD40L after incubation | Open-i
CD3− lymphocytes express CD40L after incubation with IL-2. Staining profiles of o.n. cultured lymphocytes, obtained as ... Antigens, CD3/analysis. *Antigens, CD56/analysis. *CD40 Ligand. *Histocompatibility Antigens Class I/analysis ... by double staining with anti-CD40L mAb TRAP-1 and anti-CD3 or anti-CD56 mAb. A clear TRAP-1 binding on the CD3−CD56+ population ... by double staining with anti-CD40L mAb TRAP-1 and anti-CD3 or anti-CD56 mAb. A clear TRAP-1 binding on the CD3−CD56+ population ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2196353_JEM.962210f5&req=4
*  Effects of C-K on the body weight and arthritis scores | Open-i
Antigens, CD3/immunology. *B-Lymphocytes/drug effects/immunology. *CTLA-4 Antigen/immunology ... T lymphocyte subsets, and CD28, T cell receptor (TCR), cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) and programmed ... T lymphocyte subsets, and CD28, T cell receptor (TCR), cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) and programmed ... Splenic T and B lymphocytes were positively isolated using anti-CD3-coated magnetic beads or a pan B cell isolation kit. ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4814039_aps20147f2&req=4
*  Graft Versus Host Disease Medication: Immunosuppressive agents, Immunomodulating agents, Photoactive agents, Antineoplastic...
Muromonab-CD3 is a murine monoclonal antibody to the CD3 antigen of human T cells that functions as an immunosuppressant. It is ... Murine monoclonal antibody to CD3 antigen of human T cells, which functions as immunosuppressant. Monoclonal antibody ... Newer monoclonal antibodies directed against particular targets such as cytokines or antigens on cells that may have a role in ... Monoclonal antibody against CD52, antigen found on B-cells, T-cells, and almost all chronic lymphocytic leukemia (CLL) cells. ...
  https://emedicine.medscape.com/article/429037-medication
*  Autoimmunity-blocking Antibody for Tolerance in Recently Diagnosed Type 1 Diabetes - Full Text View - ClinicalTrials.gov
Anti-CD3 mAb is genetically engineered and directed against the CD3 antigen on T cells; this antibody selectively attacks the ... Experimental: Anti-CD3 mAb Plus Diabetes Standard of Care Treatment Subjects receive 1.) a 14-day course of anti-CD3 monoclonal ... Biological: Anti-CD3 mAb Other: Diabetes Standard of Care Treatment Dietary Supplement: Iron supplementation Phase 2 ... Anti-CD3 monoclonal antibody (a.k.a. hOKT3gamma1 [Ala-Ala],teplizumab, MGA031) is a humanized antibody that is commonly used to ...
  https://clinicaltrials.gov/ct2/show/NCT00129259?cond=%22type+1+diabetes%22+OR+%22Diabetes+Mellitus%2C+Type+1%22&rank=10
*  b cell small lymphocytic lymphoma stage i 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Chemical-registry-number] 0 / Antigens, CD3; EC 3.1.3.48 / Antigens, CD45. * 17. Chuang SS, Liao YL, Liou CP, Wiggins ML, Ye H ... Magro CM, Dyrsen ME: Cutaneous lymphocyte antigen expression in benign and neoplastic cutaneous B- and T-cell lymphoid ... MeSH-major] Antigens, Neoplasm / analysis. Biomarkers, Tumor / analysis. Dermatitis / immunology. Lymphoma, B-Cell / immunology ... Title] Cutaneous lymphocyte antigen expression in benign and neoplastic cutaneous B- and T-cell lymphoid infiltrates. ...
  http://www.bmlsearch.com/?kwr=b+cell+small+lymphocytic+lymphoma+stage+i+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
*  Acquisition of Ly49 Receptor Expression by Developing Natural Killer Cells | JEM
1987) Expression and function of the CD3 antigen receptor on murine CD4+8+thymocytes. Nature 330:170-173, pmid:2959867.. ... No CD3+ donor cells were detected in the spleen and no donor cells of any type were detected in the thymuses of the recipient ... 1992) Ly-49 antigen defines an αβ TCR population in i-IEL with an extrathymic maturation. Int Immunol 4:699-706, pmid:1535510. ... All isolated populations were sorted NK1.1+CD3− except in some replicates of the Ly49A−C−G2+I− (Ly49G2 single positive cell) ...
  http://jem.rupress.org/content/187/4/609
*  Type I interferon negatively controls plasmacytoid dendritic cell numbers in vivo | JEM
The second immune reaction against CD3 antigen (rabbit monoclonal, clone SP7, dilution 1:100; Thermo Fisher Scientific) was ... Antigen-presentation properties of plasmacytoid dendritic cells. Immunity. 29:352-361. doi:10.1016/j.immuni.2008.09.002. ... D) Spleen sections from uninfected (Ctrl) and MCMV-infected C57BL/6 mice were stained for Siglec-H (blue) and CD3 (brown). A ... Fluorochrome labeled anti-SiglecH (551), anti-B220 (RA3-6B2), anti-CD11c (HL3), anti-Ly6C (AL-21), anti-CD3 (145-2C11), anti- ...
  http://jem.rupress.org/content/208/12/2367
*  Peptides and Proteins: Novus Biologicals
Recombinant Protein Antigen (92). *. Recombinant Protein (52). *. Partial Recombinant Protein (31). *. Biologically Active ... CD3 epsilon (5). *. GABA-B R2 (5). *. Semaphorin 4A (5). *. Calretinin (4) ...
  https://www.novusbio.com/product-type/peptides-and-proteins?related_pathways=Signal%20Transmission
*  Abstract 1481: Preclinical validation of a novel CD133/CD3 bispecific T-cell engager (BiTE) antibody to target patient-derived...
... one arm recognizes the tumor antigen (CD133) while the second is specific to CD3 antigen. The BiTEs were constructed in four ... Further analysis showed binding of BiTEs to human T cells known to express CD3 within a population of healthy donor peripheral ... Abstract 1481: Preclinical validation of a novel CD133/CD3 bispecific T-cell engager (BiTE) antibody to target patient-derived ... Abstract 1481: Preclinical validation of a novel CD133/CD3 bispecific T-cell engager (BiTE) antibody to target patient-derived ...
  http://cancerres.aacrjournals.org/content/76/14_Supplement/1481
*  Anti-Rat (Rattus) CD3E antibody for Immunofluorescence (IF)
Antigen CD3e Molecule, epsilon (CD3-TCR Complex) (CD3E) Antibodies show synonyms for this antigen * cd3e ... Images for product: anti-CD3e Molecule, epsilon (CD3-TCR Complex) (CD3E) antibody ...
  http://www.antibodies-online.com/tcr-signaling-pathway-12/cd3e-antibody-2552/rat-if-12420/
*  Anti-Horse (Equine) CD3E antibody for Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Antigen CD3e Molecule, epsilon (CD3-TCR Complex) (CD3E) Antibodies show synonyms for this antigen * cd3e ... Synonyms: CD3E, CD3e antigen, CD3-epsilon, T-cell receptor epsilon chain, TCRE, T-cell receptors epsilon chain, T3E, CD3 ... A synthetic 13-mer peptide corresponding to aa 156-168 of the epsilon chain of human CD3 protein.. Type of Immunogen: Synthetic ... Images for product: anti-CD3e Molecule, epsilon (CD3-TCR Complex) (CD3E) (AA 156-168) antibody ...
  http://www.antibodies-online.com/tcr-signaling-pathway-12/cd3e-antibody-2552/horse-ihc-p-12404/