*  The Phosphatase Src Homology Region 2 Domain-Containing Phosphatase-1 Is an Intrinsic Central Regulator of Dendritic Cell...
Protein-tyrosine phosphatase Shp-1 is a negative regulator of IL-4- and IL-13-dependent signal transduction. J. Biol. Chem. 273 ... A similar MHC class II defect has been observed on BMDCs from paired Ig-like receptor-B (PIR-B)-deficient mice (44) that ... Innate Immunity Together with Duration of Antigen Persistence Regulate Effector T Cell Induction ... Role of the protein tyrosine phosphatase SHP-1 in interleukin-6 regulation of prostate cancer cells. Prostate 70: 1491-1500. ...
  http://www.jimmunol.org/content/186/7/3934.full
*  HLA-DR4-associated T and B cell responses to specific determinants on the IA-2 autoantigen in type 1 diabetes. - Radcliffe...
... and those to peptide 853-872 with Abs to an epitope located in the 831-862 central region of the IA-2 tyrosine phosphatase ... Receptor-Like Protein Tyrosine Phosphatases, Class 8, T-Lymphocytes, Young Adult ... HLA-DR4 Antigen, Humans, Immunophenotyping, Interleukin-10, Male, Peptides, Phenotype, ... and those to peptide 853-872 with Abs to an epitope located in the 831-862 central region of the IA-2 tyrosine phosphatase ...
  https://www.rdm.ox.ac.uk/publications/634135
*  Genomics, Circuits, and Pathways in Clinical Neuropsychiatry - 1st Edition
Sortilin-Related Receptor, LDLR Class A Repeats Containing. *Inositol Polyphosphate-5-Phosphatase ... Protein Tyrosine Kinase 2β. *Ras and Rab Interactor 3 (RIN3) and Solute Carrier Family 24 Sodium/Potassium/Calcium Exchanger, ... Triggering Receptor Expressed on Myeloid Cells 2. *CD33 (Myeloid Cell Surface Antigen CD33; Sialic Acid-Binding Immunoglobulin- ... Genetic Association of Narcolepsy With the Human Leukocyte Antigen. *Non-Human Leukocyte Antigen Genes Are Also Associated With ...
  https://www.elsevier.com/books/genomics-circuits-and-pathways-in-clinical-neuropsychiatry/lehner/978-0-12-800105-9
*  CD99 Signals Caspase-Independent T Cell Death | The Journal of Immunology
Rapid activation of the T-cell tyrosine protein kinase pp56lck by the CD45 phosphotyrosine phosphatase. Proc. Natl. Acad. Sci. ... The inhibitor of death receptor signaling, FLICE-inhibitory protein defines a new class of tumor progression factors. J. Exp. ... Anti-human class I MHC antibodies induce apoptosis by a pathway that is distinct from the Fas antigen-mediated pathway. J. ... Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck. ...
  http://www.jimmunol.org/content/166/8/4931.long
*  Idelalisib: First-in-Class PI3K Delta Inhibitor for the Treatment of Chronic Lymphocytic Leukemia, Small Lymphocytic Leukemia,...
... are activated downstream of receptor tyrosine kinases and G protein-coupled receptors (GPCRs) and via interaction with the ... IL4 receptor, or Toll-like receptor 4 (TLR 4) stimulation, leading to defects in T-cell-dependent and -independent antigen- ... or inactivation of phosphatases such as PTEN that catabolize PIP3 (4, 7). ... Fc-gamma receptor (FcγR), TLR, C-X-C chemokine receptor type 4/5 (CXCR4/5), and the TNF receptor family (9, 22). PI3Kδ ...
  http://clincancerres.aacrjournals.org/content/21/7/1537
*  Desmoglein-1 - Wikipedia
"Intracellular substrates of brain-enriched receptor protein tyrosine phosphatase rho (RPTPrho/PTPRT)". Brain Res. 1116 (1): 50- ... Desmoglein List of target antigens in pemphigus List of conditions caused by problems with junctional proteins GRCh38: Ensembl ... Martel P, Gilbert D, Busson M (2003). "Epistasis between DSG1 and HLA class II genes in pemphigus foliaceus". Genes Immun. 3 (4 ... The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus ...
  https://en.wikipedia.org/wiki/Desmoglein-1
*  Plus it
Signalling by the W/Kit receptor tyrosine kinase is negatively regulated in vivo by the protein tyrosine phosphatase Shp1. Nat ... HLA class I light chain). These genes code for antigen-presenting proteins that present processed cellular or foreign antigens ... Genetic analysis reveals cell type-specific regulation of receptor tyrosine kinase c-Kit by the protein tyrosine phosphatase ... Receptor protein tyrosine phosphatase-μ is abundantly expressed in the lung (40) and associates with the cadherin-catenin ...
  http://clincancerres.aacrjournals.org/content/8/4/1127
*  Plus it
... cytotoxic T-lymphocyte-associated protein 4, protein-tyrosine phosphatase, nonreceptor-type 22, and interleukin-2 receptor, ... Susceptibility to T1D is inherited, with the human leukocyte antigen (HLA) class II haplotypes encoding DR3-DQ2 (DRB1*03-DQA1* ... Autoantibodies against β-cell-specific antigens, such as proinsulin and insulin, GAD65, islet antigen-2, and zinc transporter 8 ... 2B) included, for example, the DEAD box protein 58 (DDX58, better known as retinoic acid-inducible gene 1), which codes a ...
  http://diabetes.diabetesjournals.org/content/63/7/2402
*  PKCδ Impaired Vessel Formation and Angiogenic Factor Expression in Diabetic Ischemic Limbs | Diabetes
Protein tyrosine phosphatase is a group of proteins that is critical in abating cell response to growth factors by inhibiting ... tyrosine, p-PKCδ (Thr 505), PKCδ, p-VEGF receptor 2 (VEGFR2; Y1175), VEGFR2, p-PDGF receptor-β (PDGFR-β; Tyr 1009), and PDGFR-β ... Antigens were detected using anti-rabbit HRP-conjugated antibody for other Western blotting and detected with the ECL system ( ... according to the manufacturer's instructions. Detection of hypoxia-inducible factor-1α (HIF-1α) in the nucleus was quantified ...
  http://diabetes.diabetesjournals.org/content/62/8/2948.full?cited-by=yes&legid=diabetes
*  anti-CD45 antibody [EM-05] (PerCP) | GeneTex
... receptor type, C) for FACS, ICC/IF, IP, WB. Anti-CD45 mAb (GTX80171) is tested in Mouse samples. 100% Ab-Assurance. ... protein tyrosine phosphatase, receptor type, C. Background. CD45 (LCA, leukocyte common antigen) is a receptor-type protein ... Storage Instruction. Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.. Do not use after expiration ... The antibody EM-05 reacts with mouse CD45 antigen (Leukocyte Common Antigen), a single chain type I transmembrane protein ...
  http://www.genetex.com/CD45-antibody-EM-05-PerCP-GTX80171.html
*  Tyrosine phosphorylation - Wikipedia
Two important classes of tyrosine kinase in tyrosine phosphorylation are receptor tyrosine kinase and nonreceptor tyrosine ... and opposing the action of the tyrosine kinases were 108 protein phosphatases that can remove phosphate from P.Tyr in proteins ... Protein phosphorylation Eckhart W, Hutchinson MA, Hunter T (1979). "An activity phosphorylating tyrosine in polyoma T antigen ... whereas protein tyrosine phosphatases (PTPs) remove the phosphate group from phosphotyrosine. Tyrosine phosphorylation of ...
  https://en.wikipedia.org/wiki/Tyrosine_phosphorylation
*  CD79A - Wikipedia
"Identification of the tyrosine phosphatase PTP1C as a B cell antigen receptor-associated protein involved in the regulation of ... "The B-cell antigen receptor of the five immunoglobulin classes". Nature. 352 (6338): 777-81. doi:10.1038/352777a0. PMID 1881434 ... "Multiple components of the B cell antigen receptor complex associate with the protein tyrosine phosphatase, CD45". The Journal ... "Dual role of the tyrosine activation motif of the Ig-alpha protein during signal transduction via the B cell antigen receptor ...
  https://en.wikipedia.org/wiki/CD79A
*  Most recent papers with the keyword ptprd | Read by QxMD
Polymorphism of Receptor-Type Tyrosine-Protein Phosphatase Delta gene in the development of non-alcoholic fatty liver disease. ... Recognition of major histocompatibility complex (MHC) class I antigens on tumor cells by cytotoxic T cells is involved in T ... Protein tyrosine phosphatase receptor-type δ (PTPRD) is frequently inactivated in human cancers. This study investigated the ... Protein tyrosine phosphatase receptor-type δ acts as a negative regulator suppressing breast cancer. ...
  https://www.readbyqxmd.com/keyword/113703
*  WO2001061053A9 - Protein and peptide sensors using electrical detection methods - Google Patents
... for electrical detection of molecular interactions between probe molecules bound to defined regions of an array and protein or ... provides an apparatus and methods for the electrical detection of molecular interactions between a probe molecule and a protein ... INF-γ receptor alpha chain, MHC Class I, MHC Class II , T Cell Receptor, Insulin receptor, insulin receptor tyrosine kinase and ... industrial and pharmaceutical proteins, including ligands, cell surface receptors, antigens, antibodies, cytokines, hormones, ...
  https://patents.google.com/patent/WO2001061053A9/en
*  KEGG SSDB Best Search Result: ter:Tery 4410
mtm:MYCTH_2309896 hypothetical protein 453 112 ( -) 31 0.301 133 ,-, 1 phi:102102553 protein tyrosine phosphatase, receptor ty ... phy:AJ81_03285 aminotransferase class III K00821 393 109 ( -) 31 0.316 117 -, 1 rtc:APU90_01650 ATP-dependent DNA ligase 323 ... sphp:LH20_15320 surface antigen 308 107 ( 4) 30 0.321 78 ,-, 2 sphq:BWQ93_08535 glucan endo-1,3-beta-D-glucosidase 311 107 ... gga:417853 protein tyrosine phosphatase, receptor type K05694 2211 114 ( -) 32 0.325 83 -, 1 kra:Krad_4304 2-dehydropantoate 2- ...
  http://www.kegg.jp/ssdb-bin/ssdb_best?org_gene=ter:Tery_4410
*  T-cell receptor - Wikipedia
... a transmembrane protein whose intracellular tail functions as a tyrosine phosphatase that activates Src family kinases Zap70 - ... On cytotoxic T cells, this co-receptor is CD8 that is specific for MHC class I. Extracellularly, the TCR co-receptor defines ... The generation of TCR diversity is similar to that for antibodies and B cell antigen receptors. It arises mainly from genetic ... Cardiff University UMich Orientation of Proteins in Membranes protein/pdbid-2hac - Zeta-zeta dimer of T cell receptor T-Cell ...
  https://en.wikipedia.org/wiki/T-cell_receptor
*  Gary Peltz | Stanford Medicine Profiles
The activation of protein tyrosine kinases is a critical event in T cell antigen receptor (TCR)-mediated signaling. One ... This study demonstrates that the proteins secreted by Y. enterocolitica, including a protein with tyrosine phosphatase activity ... Education News. Diversity center for med school opens in Lane Library Explore Education. Learn how we empower tomorrow's ... tyrosine-phosphorylated proteins co-precipitating with a Grb2 fusion protein after receptor activation were analyzed. Ligation ...
  https://med.stanford.edu/profiles/gary-peltz
*  Fc receptor - Wikipedia
The abrogation of ITAM activation signaling is caused by inhibition of protein tyrosine kinases of Src family, and by ... Firan M, Bawdon R, Radu C, Ober RJ, Eaken D, Antohe F, Ghetie V, Ward ES (Aug 2001). "The MHC class I-related receptor, FcRn, ... IgE antibodies bind to antigens of allergens. These allergen-bound IgE molecules interact with Fcε receptors on the surface of ... the phosphatases SHP-1 and SHIP-1 inhibit signaling by Fcγ receptors. Binding of ligand to FcγRIIB leads to phosphorylation of ...
  https://en.wikipedia.org/wiki/Fc_receptor
*  Recognition of HLA Class I-Restricted β-Cell Epitopes in Type 1 Diabetes | Diabetes
... and the protein tyrosine phosphatase insulinoma-associated antigen 2 (IA-2) (4,5). Because β-cell damage, precipitated by CTL ... and upon T-cell receptor activation, they induce β-cell apoptosis. ... islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP), insulin, insulinoma-associated antigen 2 (IA-2 ... pp65 protein, NLVPMVATV), or peptide known to bind to HLA-B8 but not HLA-A*0201 (EBV/B8, BZLF1 antigen, RAKFKQLL). A: ...
  http://diabetes.diabetesjournals.org/content/55/11/3068
*  Co-expression of ILT4/HLA-G in human non-small cell lung cancer correlates with poor prognosis and ILT4-HLA-G interaction...
Immunoreceptor tyrosine-based inhibitory motifs. SHP. Protein tyrosine phosphatase. VEGF-C. Vascular endothelial growth factor- ... Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind ... Soluble human leukocyte antigen-g5 activates extracellular signal-regulated protein kinase signaling and stimulates trophoblast ... activates nuclear factor-kappaB through IkappaBalpha kinase-independent but EGF receptor-kinase dependent tyrosine 42 ...
  https://link.springer.com/article/10.1007/s13277-016-5002-5
*  PTPIA2 / PTPRN抗体|Abcam中国|Anti-PTPIA2 / PTPRN抗体(ab37523)
Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.. Contains 1 tyrosine-protein phosphatase domain ... Islet cell antigen 512 antibody. *Islet cell autoantigen 3 antibody. *Protein tyrosine phosphatase like N antibody ... Receptor type tyrosine protein phosphatase like N antibody. *Receptor-type tyrosine-protein phosphatase-like N antibody ... Protein tyrosine phosphatase like N precursor antibody. *Protein tyrosine phosphatase receptor type N antibody ...
  http://www.abcam.cn/ptpia2-ptprn-antibody-ab37523.html
*  PTPRK - Wikipedia
"Identification of a mutated receptor-like protein tyrosine phosphatase kappa as a novel, class II HLA-restricted melanoma ... and thus represents a receptor-type PTP (RPTP). The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an ... The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Protein tyrosine phosphatases ... "The crystal structure of human receptor protein tyrosine phosphatase kappa phosphatase domain 1". Protein Sci. 15 (6): 1500-5. ...
  https://en.wikipedia.org/wiki/PTPRK
*  Raif Geha, MD | Research + Innovation | Boston Children's Hospital
Protein tyrosine phosphorylation induced via the IgG receptors Fc gamma Ri and Fc gamma RII in the human monocytic cell line ... synthesis requires interleukin 4 and T/B cell interactions involving the T cell receptor/CD3 complex and MHC class II antigens ... Role of protein tyrosine kinases and phosphatases in isotype switching: crosslinking CD45 to CD40 inhibits IgE isotype ... Engagement of MHC class II molecules by staphylococcal superantigens activates src-type protein tyrosine kinases. Eur J Immunol ...
  http://www.childrenshospital.org/research-and-innovation/research/researchers/g/raif-geha
*  Breast cancer classification and prognosis based on gene expression profiles from a population-based study | PNAS
This subgroup showed higher expression of a protein tyrosine phosphatase type IVA member, tumor necrosis factor receptor- ... The dendrogram further branched into smaller subgroups within the ER+ and ER-classes. Although our sample size was not large ... However, the melanoma tumor antigen PRAME was highlighted and should be further investigated in breast cancer as a potential ... Breast Cancer Subtype Approximated by Estrogen Receptor, Progesterone Receptor, and HER-2 Is Associated With Local and Distant ...
  http://www.pnas.org/content/100/18/10393?ct=
*  KLRD1 - Wikipedia
... association of NKG2A with SHP-1 and SHP-2 protein-tyrosine phosphatases". European Journal of Immunology. 28 (1): 264-76. doi: ... "Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for ... KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has ... The protein encoded by CD94 gene is a lectin, cluster of differentiation and a receptor that is involved in cell signaling and ...
  https://en.wikipedia.org/wiki/KLRD1