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*  Unusual manifestations of the antiphospholipid syndrome | Springer for Research & Development
The classical clinical picture of the antiphospholipid syndrome (APS) is characterized by venous and arterial thromboses, fetal ... losses and thrombocytopenia, in the presence of antiphospholipid... ... Antiphospholipid syndrome anticardiolipin antibodies lupus anticoagulant antiphospholipid antibodies This is a preview of ... in the presence of antiphospholipid antibodies (aPL), namely lupus anticoagulant (LA), anticardiolipin antibodies (aCL), or ...
  https://rd.springer.com/article/10.1385/CRIAI%3A25%3A1%3A61
*  Pr-conceptional Progesterone for Unexplained Recurrent Miscarriage - Full Text View - ClinicalTrials.gov
Antiphospholipid syndrome (lupus anticoagulant and/or anticardiolipin antibodies [IgG or IgM]); other recognised thrombophilic ... thyroid disease and systemic lupus erythematosus (SLE). ...
  https://clinicaltrials.gov/ct2/show/NCT01670929?recr=Open&cond=%22Abortion%2C+Spontaneous%22&rank=12
*  A randomized clinical trial of unfractioned heparin for treatment of sepsis (the HETRASE study): design and rationale ...
... presence of anticardiolipin antibody, antiphospholipid syndrome, lupus anticoagulant or homocysteinemia; or patients with a ... On the other hand, in the clinical setting of sepsis, neither the anticoagulant effect nor the broad anti-inflammatory and/or ... Some biological products with anticoagulant activity have been tested in clinical trials, as complementary treatment for septic ... The rationale behind anticoagulant treatments is that certain factors -activated protein C (APC), Antithrombin (AT) and Tissue ...
  https://trialsjournal.biomedcentral.com/articles/10.1186/1745-6215-7-19
*  Calciphylaxis (Calcific uremic arteriolopathy) - ONA
Connective tissue disease (the antiphospholipid syndrome: check lupus anticoagulant, anticardiolipin antibodies, anti-beta 2- ... thus an antinuclear antibody (ANA), antineutrophil cytoplasmic antibody (ANCA), cryoglobulin, cryofibrinogen levels, and ... Hypercoagulable states (cryoglobulinemia: detected hepatitis B or C antibodies, presence of serum cryoglobulins, protein C ...
  http://www.oncologynurseadvisor.com/dermatology/calciphylaxis-calcific-uremic-arteriolopathy/article/593624/
*  JAK2V617F: Is It Sufficient as a Single Player in Splanchnic Venous Thrombosis?
Antiphospholipid IgM, anticardiolipin IgM antibodies, and confirmatory test for lupus anticoagulant (LA) were positive. ANA was ... Workup for lupus anticoagulant was negative. To rule out an acquired cause for protein S deficiency, family screening was done ... P. D. Valle, L. Crippa, A. M. Garlando et al., "Interference of lupus anticoagulants in prothrombin time assays: implications ... to interference of lupus anticoagulant IgG in PT assays [20].. We suggest that one should look beyond JAK2 in patients of MPNs ...
  https://www.hindawi.com/journals/crihem/2015/373490/
*  FRI0423 Miscarriage Risk Score in Mothers with Autoimmune Diseases | Annals of the Rheumatic Diseases
Prediction of adverse pregnancy outcome by the presence of lupus anticoagulant, but not anticardiolipin antibody, in patients ... with only Antiphospholipid Antibodies (APA), 27 (12,6%) Systemic Erythematosus Lupus (SLE), 28 (13%) SLE with APA, 44 (20,5%) ... lupus anticoagulant, IgG and IgM anticardiolipin antibodies, previous miscarriages and PAPS, while UCTD was a protective factor ... Conclusions Mother's age, lupus anticoagulant, IgG anticardiolipin and previous miscarriages may be risk factors for worse ...
  http://ard.bmj.com/content/73/Suppl_2/539.3
*  Calciphylaxis (Calcific uremic arteriolopathy)
Connective tissue disease (the antiphospholipid syndrome: check lupus anticoagulant, anticardiolipin antibodies, anti-beta 2- ... thus an antinuclear antibody (ANA), antineutrophil cytoplasmic antibody (ANCA), cryoglobulin, cryofibrinogen levels, and ... Hypercoagulable states (cryoglobulinemia: detected hepatitis B or C antibodies, presence of serum cryoglobulins, protein C ... Updated Guidelines for Interventional Pain Procedures in Patients on Antiplatelet, Anticoagulant Treatment ...
  http://www.clinicalpainadvisor.com/dermatology/calciphylaxis-calcific-uremic-arteriolopathy/article/593628/
*  Idiopathic Intracranial Hypertension (IIH) Workup: Approach Considerations, Laboratory Studies, MRI and CT
... antiphospholipid/anticardiolipin antibodies, lupus anticoagulant, and platelet aggregation studies. ... 59] Some authors advocate screening for anticardiolipin antibodies and other procoagulant states in all patients with IIH who ... An increased incidence of anticardiolipin antibodies has been reported in patients with IIH. Accordingly, some authors advocate ... Leker RR, Steiner I. Anticardiolipin antibodies are frequently present in patients with idiopathic intracranial hypertension. ...
  https://emedicine.medscape.com/article/1214410-workup
*  Case Reports - Reviews sub-cluster 12
... anticardiolipin antibodies, lupus anticoagulant, antiphospholipid antibodies, adrenal, thyroid, parathyroid, pituitary, ... Our objective was to study the endocrinologic manifestations of the antiphospholipid syndrome (APS). We reviewed the medical ... Thyroid hormone measurement revealed clinical hypothyroidism with elevated anti-thyroid antibodies, neck ultrasonography showed ...
  http://www.biomedsearch.com/cluster/53/Case-Reports-Reviews/sub-12-p4.html
*  Cardiolipin Antibodies
Cardiolipin antibody tests help diagnose the cause of blood clots, recurrent miscarriages or antiphospholipid syndrome (APS). ... antibodies are autoantibodies that can affect blood clotting. ... Anticardiolipin Antibodies and the Lupus Anticoagulant in ... such as lupus. They are frequently detected with other antiphospholipid antibodies, such as lupus anticoagulant and anti-beta-2 ... Antiphospholipid Antibodies; Beta-2 Glycoprotein 1 Antibodies; Anti-phosphatidylserine; Autoantibodies; Lupus Anticoagulant ...
  https://labtestsonline.org/tests/cardiolipin-antibodies
*  Antiphospholipid antibodies definition | Drugs.com
Definition of antiphospholipid antibodies. Provided by Stedman's medical dictionary and Drugs.com. Includes medical terms and ... includes lupus anticoagulant, Venereal Disease Research Laboratories, and anticardiolipin antibodies. Associated with immune- ... antiphospholipid antibodies. Definition: antibodies directed against phosphorylated polysaccharide esters of fatty acids, ...
  https://www.drugs.com/dict/antiphospholipid-antibodies.html
*  How to treat women with antiphospholipid antibodies in pregnancy? | Annals of the Rheumatic Diseases
1990) Antiphospholipid antibodies: anticardiolipin and the lupus anticoagulant in systemic lupus erythematosus (SLE) and in non ... On behalf of the Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibody of the Scientific and Standardisation Committee ... The Second International Anti-cardiolipin Standardization Workshop/the Kingston Anti-Phospholipid Antibody Study (KAPS) Group. ... 1998) Many faces of lupus anticoagulants. Lupus 7(suppl 2) S18-S22, . ...
  http://ard.bmj.com/content/60/1/1
*  Blood Tests
Antinuclear antibodies (ANA). *Antiphospholipid antibodies (APL), Anticardiolipin antibodies (ACL), Lupus anticoagulant (LA) ...
  http://www.strokecenter.org/patients/stroke-diagnosis/blood-tests/
*  Antiphospholipid Syndrome in Pregnancy - AHealthyMe - Blue Cross Blue Shield of Massachusetts
In this condition, your body makes antibodies that attack a kind of fat in cells. This makes your blood clot too easily. ... Antiphospholipid syndrome is an autoimmune disease. This happens when your immune system fights against normal cells. ... Lupus anticoagulant. *Anticardiolipin antibody. *Anti-β2-glycoprotein. Your healthcare provider may need to repeat all or some ... Antiphospholipid Syndrome in Pregnancy. What is antiphospholipid syndrome?. Antiphospholipid syndrome is an autoimmune disease ...
  http://www.ahealthyme.com/Library/DiseasesConditions/Adult/Orthopedic/90,P02432
*  Antiphospholipid Antibodies: Reference Range, Collection and Panels, Background
The most commonly used tests to detect APL include lupus anticoagulant (LAC), anticardiolipin (ACL) antibodies, and anti-β2 - ... antibodies are group of antibodies directed against epitopes on plasma proteins that are uncovered by binding of these proteins ... Update of the guidelines for lupus anticoagulant detection. Subcommittee on lupus anticoagulant/antiphospholipid antibody of ... These antibodies can be detected with lupus anticoagulant (LAC), anticardiolipin antibodies (ACL), and anti-β2 -glycoprotein I ...
  https://emedicine.medscape.com/article/2116457-overview
*  Turk J Hematol: 24 (2)
Lupus anticoagulant and anticardiolipin antibodies in SLE with secondary Antiphospholipid Antibody Syndrome. Shveta Garg, ... had elevated anticardiolipin antibody titers. We concluded that the prevalence of lupus anticoagulant and anticardiolipin ... Thirty patients with systemic lupus erythematosus (SLE) and suspected secondary antiphospholipid antibody syndrome (APLAS) were ... The aim was to study the prevalence of various antiphospholipid antibodies, compare the tests used for their detection and to ...
  http://aoh.tjh.com.tr/jvi.aspx?pdir=tjh&plng=eng&volume=24&issue=2&showabs=true
*  Thrombotic thrombocytopenic purpura
Anti-cardiolipin antibody and "lupus anticoagulant" tests. Results will be positive in anti-phospholipid syndrome, but not in ... For example, bevacizumab (Avastin), a monoclonal antibody against vascular endothelial cell growth factor (VEGF); or "tinib" ... Bevacizumab (Avastin) is a monoclonal antibody against VEGF. Tinib drugs (for example, sunitinib) inhibit VEGF receptor- ... variable domain antibody fragment that suppresses VWF-platelet adhesion by binding to, and blocking VWF A1 domains in the VWF ...
  https://www.psychiatryadvisor.com/hematology/thrombotic-thrombocytopenic-purpura/article/597453/
*  Antiphospholipid Syndrome (aPL)
However, blood tests for lupus anticoagulant, anticardiolipin antibody, and anti-β2-glycoprotein may aid in the diagnosis. ... Antiphospholipid Syndrome. What is antiphospholipid syndrome?. Antiphospholipid syndrome (aPL) is an autoimmune disease in ... Antiphospholipid antibodies attack the phospholipids. This causes many different problems, including increased blood clotting. ... Cardiolipin is a type of phospholipid, and specific anticardiolipin antibodies may develop. ...
  http://www.stanfordchildrens.org/en/topic/default?id=antiphospholipid-syndrome-apl-90-P02432&sid=33195
*  Mycoplasma penetrans Bacteremia and Primary Antiphospholipid Syndrome1 - Volume 5, Number 1-February 1999 - Emerging Infectious...
... was isolated in the blood and throat of a non-HIV-infected patient with primary antiphospholipid syndrome (whose etiology and ... anticardiolipin antibodies, or lupus anticoagulant activity (1). The factor(s) causing production of the antiphospholipid ... and the presence of lupus anticoagulant (LA) antibodies (prolonged Russell viper venom time and confirmed by the STACLOT LA ... Antiphospholipid antibodies and Mycoplasma pneumoniae infection. Postgrad Med J. 1990;66:356-62. DOIPubMed ...
  https://wwwnc.cdc.gov/eid/article/5/1/99-0122_article
*  Plus it
... including antiphospholipid (lupus anticoagulant and anticardiolipin) antibodies, in patients with CTEPH [54]. Thrombophilia ... cancer or elevated antiphospholipid antibodies) than in those with transient risk factors (e.g. surgery) [12, 47]. Older age, ... The direct oral anticoagulants have shown similar efficacy and, in some cases, reduced major bleeding compared with standard ... Finally, when anticoagulant therapy has been completed, advice can be given regarding lessening an individual's risk of ...
  http://err.ersjournals.com/content/24/137/484
*  Autoimmune hemolytic anemia (including Evans syndrome)
Lupus anticoagulant and anticardiolipin antibodies may be checked to evaluate for antiphospholipid syndrome, mainly in patients ... In 50% of the cases, Evans syndrome is secondary to lupus, antiphospholipid syndrome, Sjogren's syndrome, CVID (common variable ... antiphospholipid antibody syndrome).. When do you need to get more aggressive tests:. A bone marrow biopsy might be necessary ... Such patients usually carry a low-affinity antibody, which is below the level of detection of a standard Coombs test, or can ...
  https://www.psychiatryadvisor.com/hematology/autoimmune-hemolytic-anemia-including-evans-syndrome/article/597695/
*  Clinical Evidence Handbook: Recurrent Miscarriage - American Family Physician
What are the effects of treatments for recurrent miscarriage caused by antiphospholipid syndrome? ... Antiphospholipid syndrome is defined as the presence of anticardiolipin antibodies or lupus anticoagulant antibodies, in ... Antiphospholipid syndrome, with anti-cardiolipin or lupus anticoagulant antibodies, is present in 15 percent of women with ... Antiphospholipid antibodies are present in 15 percent of women with recurrent miscarriage. ...
  https://www.aafp.org/afp/2008/1015/p977.html
*  "Catastrophic" Diagnosis of the Antiphospholipid Syndrome | Annals of Internal Medicine | American College of Physicians
Lupus anticoagulant and high levels of IgG anticardiolipin antibodies were present, without antibodies to β2-glycoprotein I. ... Lupus anticoagulant was detected, with low levels of anticardiolipin and antinuclear antibodies and no cryoglobulin, double- ... "Catastrophic" Diagnosis of the Antiphospholipid Syndrome Jean-Charles Piette, MD; Zahir Amoura, MD; Anne Foucher-Lavergne, MD ... "Catastrophic" Diagnosis of the Antiphospholipid Syndrome. Ann Intern Med. 1999;131:798-799. doi: 10.7326/0003-4819-131-10- ...
  http://annals.org/aim/article-abstract/713133/catastrophic-diagnosis-antiphospholipid-syndrome
*  The Hyperferritinemic Syndrome: macrophage activation syndrome, Still's disease, septic shock and catastrophic antiphospholipid...
... catastrophic antiphospholipid syndrome (cAPS) and septic shock, that share a similar clinical and laboratory features, and also ... Hyperferritinemia is associated with thrombocytopenia, lupus anticoagulant and anticardiolipin antibodies in SLE patients with ... European Forum On Antiphospholipid Antibodies: Catastrophic antiphospholipid syndrome (CAPS): descriptive analysis of a series ... APS antiphospholipid syndrome, DAS28 Disease Activity Score 28, ECLAM European Consensus Lupus Activity Measurement, MS ...
  https://bmcmedicine.biomedcentral.com/articles/10.1186/1741-7015-11-185
*  Plus it
Antiphospholipid syndrome-The presence of antiphospholipid antibodies (anticardiolipin antibodies or lupus anticoagulant or ... they were no more likely to be positive for lupus anticoagulant or anticardiolipin antibodies (6.12, 0.35 to 108.35) (three ... Antiphospholipid antibodies in pregnancy: prevalence and clinical associations.Br J Obstet Gynaecol1993; 100:909-13. ... The association of antiphospholipid antibodies with severe preeclampsia.Obstet Gynecol1989; 73:541-5. ...
  https://www.bmj.com/content/330/7491/565