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*  Anti-BK Virus Immune Response and Kidney Transplantation - Full Text View - ClinicalTrials.gov
Anti-BK Virus Immune Response and Kidney Transplantation (BKv). The recruitment status of this study is unknown. The completion ... BK virus infections are very frequent during months following a kidney transplantation: a viral reactivation is observed for ... Role of Specific Immune Cellular Response in the Control of BK Virus Infection: Prospective Study, Monocentric and Longitudinal ... Specific lymphocytic anti-BKv evaluated on several cohorts of patients permit to prove:. *weakness of immune cellular response ...
  https://clinicaltrials.gov/ct2/show/NCT01109186?recr=Open&intr=kidney+transplantation&rank=19
*  Fluoroquinolones and BK virus nephropathy: A myth or a reality Khalil M, Khalil M, Tan J, Khan T - Indian J Nephrol
Anti-BK virus activity of ciprofloxacin and related antibiotics. Clin Infect Dis 2005;41:1366-7. ... Keywords: BK polyomavirus, BK virus nephropathy, fluoroquinolones. How to cite this article:. Khalil M, Khalil M, Tan J, Khan T ... and the selectivity index is low and there is a need to develop more effective and less toxic anti-BK virus drugs for clinical ... Fluoroquinolones and BK virus nephropathy: A myth or a reality. M. A. M Khalil1, M. A. U Khalil2, J Tan3, T. F. T Khan4. 1 ...
  http://www.indianjnephrol.org/article.asp?issn=0971-4065
*  BK virus (Clinical Condition) - Renal and Urology News
... and high anti-BK virus IgG levels prior to transplantation. ... How does BK virus cause disease?. *. BK virus primary infection ... How does BK virus cause disease? * What other clinical manifestations may help me to diagnose and manage BK virus associated ... BK virus is a human polyomavirus that resides in the kidneys of up to 90% of healthy individuals. Reactivation of the BK virus ... BK virus PCR is checked in the blood every 4 weeks until BK virus is completely suppressed. Studies have shown decreased ...
  https://www.renalandurologynews.com/infectious-diseases/bk-virus-clinical-condition/article/610718/
*  Sortase family (IPR005754) | InterPro | EMBL-EBI
Stimulation of clones specific for dsDNA or idiotypes of anti-dsDNA as a consequence of BK virus inoculation.. Immunol. Invest. ... Sortase as a target of anti-infective therapy.. Pharmacol. Rev. 60 128-41 2008 ...
  http://www.ebi.ac.uk/interpro/entry/IPR005754
*  Cidofovir - Wikipedia
Cidofovir shows anti-BK virus activity in a subgroup of transplant recipients. Cidofovir is being investigated as a ... "Intermediate-dose cidofovir without probenecid in the treatment of BK virus allograft nephropathy". Pediatr Transplant. 10 (1 ... Cidofovir might have anti-smallpox efficacy and might be used on a limited basis in the event of a bioterror incident involving ... It has inhibitory effects on varicella-zoster virus replication in vitro although no clinical trials have been done to date, ...
  https://en.wikipedia.org/wiki/Cidofovir
*  BK Virus in Salivary Gland Disease: Treating the Potential Etiologic Agent - Full Text View - ClinicalTrials.gov
Anti-Bacterial Agents. Anti-Infective Agents. Topoisomerase II Inhibitors. Topoisomerase Inhibitors. Enzyme Inhibitors. ... It has been determined that patients with (HIVSGD) shed high levels of (BK) Virus and have evidence of replicating (BK) Virus ... Virus replication. It will be determine whether Cipro administration decreases (BK) Virus replication in patients with (HIVSGD ... BK Virus in Salivary Gland Disease: Treating the Potential Etiologic Agent. The safety and scientific validity of this study is ...
  https://clinicaltrials.gov/show/NCT02068846?order=1
*  Anti-dsDNA antibodies - Wikipedia
Human immunodeficiency virus, parvovirus B19 and BK virus are known to induce these antibodies. There is little evidence ... Epstein-Barr virus is also known to induce dsDNA antibodies, as seen after immunisation of animals with EBNA-1 epitopes. Anti- ... Reploeg MD, Storch GA, Clifford DB (July 2001). "Bk virus: a clinical review". Clin. Infect. Dis. 33 (2): 191-202. doi:10.1086/ ... Anti-dsDNA antibodies are a group of anti-nuclear antibodies (ANA) the target antigen of which is double stranded DNA. Blood ...
  https://en.wikipedia.org/wiki/Anti-dsDNA_antibodies
*  Donor-derived and BK virus positive urologic cancers after renal transplantation
In two-thirds of the patients immunosuppression was possible to change to mTOR inhibitors with anti-tumour effects. Oncological ... Donor-derived and BK virus positive urologic cancers after renal transplantation. Hellström, Vivan Uppsala University, ... Five of eleven cancers of the urinary tract were BK-virus positive. Allograft immune response against these tumours offer new ... options for cancer treatment such as immunomodulatory or anti-viral treatment in combination with modified immunosuppression. ...
  http://uu.diva-portal.org/smash/record.jsf?pid=diva2:916458
*  Renal Fellow Network: May 2008
... there are very few effective treatments demonstrated thus far which have anti-BK virus activity, and we are using leflunomide ... It also has been shown to have antiviral activity against both BK virus and CMV virus, which is why I've seen this adopted in ... On the anti-emergent dialysis side: His K isn't all that high and we could try & get it down with kayexalate; we could give him ... After multiple pregnancies, they develop anti-NEP antibodies, which are able to cross the placenta and cause significant ...
  http://renalfellow.blogspot.com/2008/05/
*  Most recent papers with the keyword Bk virus | Read by QxMD
No effective anti-PyV agents are available. Several compounds have been reported to possess anti-PyV activity in vitro, but ... BK virus (BKV) is a polyomavirus that is able to cause renal dysfunction in transplanted grafts via BK virus-associated ... Occurrence of BK Virus and Human Papilloma Virus in colorectal cancer.. Adrian Jarzyński, Przemysław Zając, Remigiusz Żebrowski ... Decoy cells are related to Polyomaviruses (JC virus [JCV] and BK virus [BKV]), which are recognized worldwide due to potential ...
  https://www.readbyqxmd.com/keyword/16367
*  ARMS - Rapidly Generated Multivirus-Specific CTLs for the Prophylaxis And Treatment of EBV, CMV, Adenovirus, HHV6, and BK Virus...
For fungal infections patients must be receiving definitive systemic anti-fungal therapy and have no signs of progressing ... BK virus (BKV) and human herpes virus 6 (HHV6).. Adenovirus is a virus that usually causes symptoms of a common cold, but can ... Epstein-Barr virus. EBV. Human polyomavirus type I. BK virus. Human herpesvirus 6. HHV6. ... BK virus- Patients post transplant may develop asymptomatic BKV viruria or viremia. BK reactivation will be defined as ...
  https://clinicaltrials.gov/ct2/show/NCT01570283?term=mononucleosis&rank=9
*  Hemorrhagic cystitis after allogeneic hematopoietic stem cell transplants is the complex result of BK virus infection,...
Anti-thymocyte globulin was part of the preparative regimen in all transplants with the exception of combinations containing ... Polyoma virus studies. We prospectively performed quantitative PCR for BK virus on urine samples collected before admission, ... Among patients who were BK virus positive prior to transplant (n=96), the median log BK viral load pre-hematopoietic stem cell ... Polyomavirus hominis 1 (genus Polyomaviridae), the BK virus, is a non-encapsulated DNA virus that is highly prevalent in ...
  http://www.haematologica.org/content/95/7/1183
*  Daily Entries | My Kidney Transplant Story
We discussed treatment options for BK. There is an anti-viral that works well with BK Virus but, of course, is nephrotoxic. So ... 11-6-12/BK Virus Getting Better, but In Rejection Again. First, the good news. The BK Virus has dropped about 30% in my blood ... of healthy hemoglobin that conceivably contains anti-bodies to BK virus. Most people have BK and suppress, which I cannot do ... BK Virus is a virus that is found in 80+% of people, but lies dormant in those with a healthy immune system. ...
  https://mykidneytransplantstory.com/daily-entries/
*  BK virus
Ltd., BK virus test at home is available in Delhi India ... BK virus test is conducted by experienced pathologists and ... Anti smoothmuscle antibody (ASMA). (RLS29) - 1900. *. Anti Sperm Antibody. (RLS30) - 1800. *. Anti streptolysin ?O?. (RLS31) - ...
  https://www.rlifespan.com/tests/BK+virus.html
*  Clinical significance of the presence of anti-human leukocyte antigen-donor specific antibody in kidney transplant recipients...
BK virus associated nephropathy; GN, glomerulonephritis. ... Keywords: Anti-human leukocyte antigen-donor specific antibody ... In case, in a patient, the anti-HLA antibody detected by LSA assay corresponded to the HLA-type of the donor, it was classified ... The impact of donor-specific anti-HLA antibodies on late kidney allograft failure. Nat Rev Nephrol 2012;8:348-357.. ... HLA-DSA, anti-human leukocyte antigen-donor specific antibody; ADPKD, autosomal dominant polycystic kidney disease; ABO IKT, ...
  http://kjim.org/journal/view.php?doi=10.3904/kjim.2016.107
*  Kidney Transplantation: Prevention and Management of Transplant Associated Complications - Polyoma BK Virus Infection
Although not backed by data, the anti-metabolite component of the regimen is usually reduced or discontinued. ... Does this patient have BK virus infection?. BK virus (BKV) is a DNA virus that typically infects children and remains latent in ... "BK virus nephropathy and kidney transplantation". Clin J Am Soc Nephrol. vol. 2. 2007. pp. S36-46. ... How should patients with BK virus infection be managed?. *. Early removal of uretral stents in all renal tranplant patients. ...
  https://www.infectiousdiseaseadvisor.com/nephrology-hypertension/kidney-transplantation-prevention-and-management-of-transplant-associated-complications--polyoma-bk-virus-infection/article/616586/
*  VC insiders inject $16M into Chimerix | FierceBiotech
... and BK virus. CMX001 is also being studied as a possible treatment for smallpox. And Chimerix is planning to push the anti-HIV ...
  https://www.fiercebiotech.com/biotech/vc-insiders-inject-16m-into-chimerix?cmp-id=OTC-RSS-FB0
*  Medication Coverage
You may also be prescribed some medications for certain viral infections like hepatitis B, cytomegalovirus (CMV), or BK virus. ... It's essential that you take anti-rejection medications at the same time every day and 12 hours apart to avoid missing doses ... There are also other preventative anti-infective medications that you may need to help your immune system fight certain ... After your transplant, you'll need to take important transplant medications called immunosuppressants (anti-rejection ...
  http://www.transplant.bc.ca/transplant-and-medications/Pages/Medication-Coverage.aspx
*  Renal Fellow Network: May 2014
IVIg presumably contains anti-BK antibodies, as the virus is ubiquitous in the general population. However, whether these ... BK Polyoma virus nephropathy (PVN): IVIg may have a role in the treatment of (PVN), particularly in cases where acute rejection ... IVIg has various anti-infections and anti-inflammatory effects via mechanisms that are still incompletely understood. The ... It must be noted that IVIg may interfere with anti-HLA titers, causing false-positive results so it is important to send levels ...
  http://renalfellow.blogspot.com/2014/05/
*  MDS AML Research Projects - Moon Shots Program | MD Anderson Cancer Center
... and BK virus (BKV) to prevent infections by these two common viruses. With current clinical trials already underway, we're ... Anti-viral immunity is diminished following allogeneic stem cell transplants, which leads to an increased risk of life ... The current anti-viral drug portfolio used to treat these infections is sometimes ineffective and cellular therapy strategies ... The curative effect of allogeneic SCTs experienced by some patients is largely due to the anti-leukemic activity of specific ...
  https://www.mdanderson.org/cancermoonshots/cancer-types/Leukemia_MDS_AML/Leukemia-MDS-AML-Research.html
*  Kidney Transplantation: Transplant Immunology and Use of Immunosuppression - ONA
BK virus PCR: BK virus is a polyoma virus, related to JC virus, known to cause nephropathy in kidney transplant patients. It ... Anti-human globulin (AHG) is now usually being added before complement to increase the sensitivity of the crossmatch. ... Once urine BK becomes positive at high levels, BK should be checked in the blood. Most centers routinely check BK in the blood ... Polyomavirus: BK virus present in the blood and especially on pathologic examination is a marker for over-immunosuppression and ...
  http://www.oncologynurseadvisor.com/nephrology-hypertension/kidney-transplantation-transplant-immunology-and-use-of-immunosuppression/article/616141/
*  Pediatric Posttransplant Lymphoproliferative Disease: Overview, Incidence, Risk Factors
27] However, other studies have documented an increased risk for BK virus nephropathy and CMV infection with mycophenolate use. ... anti-CD20 tagged to I131) and ibritumomab (anti-CD20 tagged to Y90). Resveratrol has shown some promise in in vitro models. [59 ... Epstein-barr virus gene expression in the peripheral blood of transplant recipients with persistent circulating virus loads. J ... Although the EB virus can express up to 100 genes, in the posttransplant situation only 9-10 genes are expressed. The EB genome ...
  https://emedicine.medscape.com/article/1013758-overview
*  Karthik Ranganna, MD: Nephrology - Drexel University College of Medicine
Incidence of BK virus nephropathy in HIV positive renal transplant recipients'. Irfan Ahmed, Dwight Matthew, Satyam Arora, Gary ... Use of pre-operative plasmapheresis and IVIG to reduce the risk of kidney graft thrombosis in patients with lupus and anti- ... Low rate of BK viremia and nephropathy in large single center series of HIV + Kidney transplant recipients'. Shabnum Haleem, ... Acute antibody mediated rejection in DSA negative anti-MICA antibody positive patient'. Hiral Desai, Matthew Dwight, Alden ...
  https://drexel.edu/medicine/faculty/profiles/karthik-ranganna/
*  Human Polyomaviruses in Skin Diseases
Until 2006, BK virus (BKV), JC virus (JCV), and simian virus 40 (SV40) were the only polyomaviruses known to circulate in the ... of the human population showing anti-SV40 antibodies [9]. In 2007, two new human polyomaviruses were described. One virus was ... "DNA from BK virus and JC virus and from KI, WU, and MC polyomaviruses as well as from simian virus 40 is not detected in non-UV ... Until 2006, BK virus and JC virus, named after the initials of the patients from which they were first isolated, were the only ...
  https://www.hindawi.com/journals/pri/2011/123491/