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*  Peroxisome Proliferator-Activated Receptor-γ Is Involved in the Control of Renin Gene Expression | Hypertension
Renin-Angiotensin System. Peroxisome Proliferator-Activated Receptor-γ Is Involved in the Control of Renin Gene Expression. ... Two microliters of antibody were applied in lanes 6 to 12 as follows: in lane 6, nonspecific anti-rabbit antibody (Santa Cruz, ... 1,25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin system. J Clin Invest. 2002; 110: 229-238 ... Renin is the rate-limiting factor of the renin-angiotensin-aldosterone-system, which is of fundamental importance to the ...
  http://hyper.ahajournals.org/content/50/5/939
*  Tissue and gene specificity of mouse renin expression. | Hypertension
... which with converting enzyme processes angiotensinogen to the potent vasopressor angiotensin II. Some strains of mice appear to ... Sequence analysis of a 319 bp renin cDNA recombinant isolated from a kidney library from the two-gene strain DBA/2Ha ... carry a duplication of the renin structural gene (Ren-2) near the Ren-1 locus. Strains with the gene duplication can exhibit as ...
  http://hyper.ahajournals.org/content/6/4/597
*  US Patent # 9,708,306. Benzimidazole derivatives and preparation process and pharmaceutical uses thereof - Patents.com
... angiotensin-converting enzyme inhibitor (ACEI, Pooley), Angiotensin II AT1 receptor blockers (ABR, Sartans), are continuously ... By inhibiting the activity of the ACE, on one hand, they can inhibit generations of angiotensin II so as to exert the function ... C. The reaction was monitored by the TLC (PE:EA=1:1) to detect that two new points were formed, and the raw materials were ... The unilateral renal artery of the rates were ligated to form two-kidney, one-clip renovascular hypertensive rat (RHR) models. ...
  http://patents.com/us-9708306.html
*  Abstract 12091: Aldosterone Enhances Cardiac Rupture After Myocardial Infarction Through Calcium/Calmodulin-Dependent Protein...
... is activated by catecholamines and angiotensin II, and CaMKII inhibition prevents isoproterenol- and angiotensin II-mediated ... Excessive activation of β-adrenergic, angiotensin II, and aldosterone signaling pathways promotes mortality after myocardial ... The multifunctional calcium/calmodulin-dependent protein kinase II (CaMKII) ... Aldosterone Enhances Cardiac Rupture After Myocardial Infarction Through Calcium/Calmodulin-Dependent Protein Kinase II. B. ...
  http://circ.ahajournals.org/content/124/Suppl_21/A12091
*  Effectiveness of Aldosterone Blockade in Patients With Diabetic Nephropathy | Hypertension
Local angiotensin II and transforming growth factor-beta 1 in renal fibrosis of rats. Hypertension. 2000; 35: 1078-1084. ... Arutyunov et al28 also demonstrated that combination therapy with an angiotensin II receptor antagonist and spironolactone ... Rise in plasma concentration of aldosterone during long-term angiotensin II suppression. J Endocrinol. 1981; 91: 457-465. ... Aldosterone escape during angiotensin-converting enzyme inhibitor therapy in chronic heart failure. J Card Fail. 1996; 2: 47-54 ...
  http://hyper.ahajournals.org/content/41/1/64
*  Angiotensin III Depressor Action in the Conscious Rabbit Is Blocked by Losartan but not PD 123319 | Hypertension
The half-lives of angiotensin II, angiotensin II-amide, angiotensin III, Sar1-Ala8-angiotensin II and renin in the circulatory ... Two angiotensin II binding sites in rat brain revealed using [125I] Sar1 Ile8 angiotensin II and selective non peptide ... Effects of des-Asp-angiotensin I on the contractile action of angiotensin II and angiotensin III. Eur J Pharmacol. 1995;278:175 ... Comparative effects of angiotensin II and its degradation products angiotensin III and angiotensin IV in rat aorta. Br J ...
  http://hyper.ahajournals.org/content/35/1/130
*  IJMS | Free Full-Text | Angiotensin-Converting Enzymes Play a Dominant Role in Fertility | HTML
Moreover, alterations in the expression of angiotensin-converting enzyme-1, angiotensin-converting enzyme-2, and angiotensin- ... An accumulating body of evidence has shown that the renin-angiotensin system is involved in the fertility problems observed in ... However, as a pseudogene in humans, further studies are needed to explore whether the abnormal angiotensin-converting enzyme-3 ... In this review, the relationship between angiotensin-converting enzymes and fertile ability is summarized, and a new procedure ...
  http://mdpi.com/1422-0067/14/10/21071/htm
*  New Renin Inhibitor VTP-27999 Alters Renin Immunoreactivity and Does Not Unfold ProreninNovelty and Significance | Hypertension
... renin-angiotensin system blockade beyond angiotensin II). ... because it interferes with the angiotensin II-renin negative ... High-affinity prorenin binding to cardiac man-6-P/IGF-II receptors precedes proteolytic activation to renin. Am J Physiol Heart ... including the mannose 6-phosphate/insulin-like growth factor II receptor and the (pro)renin receptor.19,20 ... These levels are ≈2-fold higher than the prorenin levels measured with the direct ELISA in the same samples (109±9 pg/mL; P, ...
  http://hyper.ahajournals.org/content/61/5/1075
*  The lack of association between angiotensin-converting enzyme gene insertion/deletion polymorphism and nicotine dependence in...
Blood-borne angiotensin II is generated from angiotensinogen via cleavage by renin and angiotensin-converting enzyme (ACE), an ... In addition to angiotensin II, other potential ACE substrates, such as substance P and neurotensin, which also influence ... The lack of association between angiotensin-converting enzyme gene insertion/deletion polymorphism and nicotine dependence in ... The lack of association between angiotensin-converting enzyme gene insertion/deletion polymorphism and nicotine dependence in ...
  https://repository.medri.uniri.hr/en/islandora/object/medri%3A1447
*  Glomerular and vascular atrial natriuretic factor receptors in saralasin-sensitive and -resistant two-kidney, one-clip...
150 mm Hg or higher were classified according to their sensitivity to the blood pressure-lowering effect of the angiotensin II ... We have investigated whether there is a relation between renin dependency of two-kidney, one-clip (2K1C) hypertensive rats and ... Glomerular and vascular atrial natriuretic factor receptors in saralasin-sensitive and -resistant two-kidney, one-clip ... Glomerular and vascular atrial natriuretic factor receptors in saralasin-sensitive and -resistant two-kidney, one-clip ...
  http://circres.ahajournals.org/content/63/3/563
*  Racial Difference in the Relationship of an Angiotensin I-Converting Enzyme Gene Polymorphism to Serum Angiotensin I-...
Effect of intrarenal angiotensin II blockade on renal function in conscious dogs. Circ Res. 1977;40:174-177. ... Evidence from transfection studies suggests that ACE expression may be related to actions conveyed by angiotensin II2 ; thus, ... of the dicarboxypeptidase ACE include the metabolism of bradykinin and the conversion of angiotensin I to angiotensin II.1 ... Evidence for direct local effect of angiotensin in vascular hypertrophy: in vivo gene transfer of angiotensin converting enzyme ...
  http://hyper.ahajournals.org/content/27/1/62
*  The assessment of renal function in relation to the use of drugs in elderly in nursing homes; a cohort study
... angiotensin-converting enzyme -inhibitors/angiotensin receptor blockers and digoxin. Descriptive statistics and the Kappa test ...
  http://liu.diva-portal.org/smash/record.jsf?pid=diva2:508144
*  On the Biological Actions of Intracellular Angiotensin | Hypertension
In the case of angiotensin II, a small but growing body of evidence has developed to indicate that angiotensin II does indeed ... and angiotensin II dialyzed into rat cardiac cells. The evidence for the influence of an intracellular AT1-like angiotensin II ... if intracrine angiotensin II stimulates the cellular production and secretion of angiotensin II with a resulting upregulation ... the present review discusses the potential role of intracellular angiotensin II, called intracrine angiotensin II, in ...
  http://hyper.ahajournals.org/content/35/6/1189
*  Angiotensin II receptor - Wikipedia
The angiotensin II receptors, (AGTR1) and (AGTR2), are a class of G protein-coupled receptors with angiotensin II as their ... angiotensin II. The AT1 and AT2 receptors share a sequence identity of ~30%, but have a similar affinity for angiotensin II, ... The angiotensin receptor is activated by the vasoconstricting peptide angiotensin II. The activated receptor in turn couples to ... The AT4 receptor is activated by the angiotensin II metabolite angiotensin IV, and may play a role in regulation of the CNS ...
  https://en.wikipedia.org/wiki/Angiotensin_II_receptor
*  angiotensin II | Hypertension
Angiotensin II Type 1 Receptor Mechanoactivation Involves RGS5 (Regulator of G Protein Signaling 5) in Skeletal Muscle Arteries ... Apelin Is a Negative Regulator of Angiotensin II-Mediated Adverse Myocardial Remodeling and DysfunctionNovelty and Significance ... Vascular ADAM17 (a Disintegrin and Metalloproteinase Domain 17) Is Required for Angiotensin II/β-Aminopropionitrile-Induced ... J Determines Responses to Ang II/DOCA and DPP4 Gene Deletion Jianzhong An, Alex Meuth, Shawn Bender, Annayya Aroor and Ravi ...
  http://hyper.ahajournals.org/keyword/angiotensin-ii
*  Angiotensin II, human
... ; The octapeptide angiotensin II (Ang II) exerts a wide range of effects on the cardiovascular system. It ... Ang II is formed by cleavage of Ang I by the angiotensin-converting enzyme (ACE) or chymases. Human heart chymase, a ... hydrolyzes the Phe8-His9 bond to yield the octapeptide hormone angiotensin II and His-Leu.; DRVYIHPF; H-Asp-Arg-Val-Tyr-Ile-His ... 2010). Angiotensin II/angiotensin II type I receptor (AT1R) signaling promotes MCF-7 breast cancer cells survival via PI3- ...
  https://www.anaspec.com/products/product.asp?id=32793
*  Angiotensin ii | Define Angiotensin ii at Dictionary.com
... angiotensin I) and two varieties (angiotensin II and angiotensin III) that elevate blood pressure and stimulate the adrenal ... Angiotensin ii definition, any of three oligopeptides occurring in plasma, an inactive form ( ... angiotensin ii in Medicine Expand. angiotensin II n. An octapeptide that is a potent vasopressor and a powerful stimulus for ... Angiotensin II is formed from inactive angiotensin I by the action of angiotensin-converting enzyme (or ACE). See also ACE ...
  http://www.dictionary.com/browse/angiotensin-ii
*  angiotensin II receptor Protein Superfamily Detail
Term: angiotensin II receptor. ID: PIRSF038557 Mouse Protein Superfamily Annotations. Select one or more mouse PIRSF members to ...
  http://www.informatics.jax.org/vocab/pirsf/PIRSF038557
*  Angiotensin II and Coronary Sympathetic Vasodilation | Circulation
Angiotensin II and Coronary Sympathetic Vasodilation. Kenneth M. Kessler, Rhonda M. Kessler ... There is no question that angiotensin II can play its enhancing effects on the sympathetic nervous system at various levels and ... Saino A, Pomidossi G, Perondi R, Valentini R, Rimini A, Di Francesco L, Mancia G. Intracoronary angiotensin II potentiates ... The suggestion is that higher local concentrations of either angiotensin II or perindoprilat are achieved when a vessel is ...
  http://circ.ahajournals.org/content/97/18/1873
*  Angiotensin II receptor blockers (ARBs) | HealthLink BC
All medicines can cause side effects. Many people don't have side effects. And minor side effects sometimes go away after a while. But sometimes side effects can be a problem or can be serious. If you're having problems with side effects, talk to your doctor. He or she may be able to lower your dose or change to a different medicine. You will likely have regular blood tests to monitor how the medicine is working in your body and to see if this medicine is causing problems.. Always be sure you get specific information on the medicine you're taking. For a full list of side effects, check the information that came with the medicine you're using. If you have questions, talk to your pharmacist or doctor. ...
  https://www.healthlinkbc.ca/health-topics/pl1009
*  Angiotensin II, Oxidant Signaling, and Hypertension | Hypertension
... is critical in angiotensin II (Ang II)-mediated regulation of blood pressure and hypertension.4,5 Using an established viral ... Angiotensin II, Oxidant Signaling, and Hypertension. Down to a T?. Robin L. Davisson, Matthew C. Zimmerman ... Superoxide mediates angiotensin II-induced influx of extra cellular calcium in neural cells. Hypertension. 2005; 45: 717-723. ... Hypertension caused by angiotensin II infusion involves increased superoxide production in the central nervous system. Circ Res ...
  http://hyper.ahajournals.org/content/55/2/228
*  Angiotensin II modulates CD40 exp... preview & related info | Mendeley
AngII (angiotensin II), which induces oxidative stress and inflammation, is ... ... AngII (angiotensin II), which induces oxidative stress and inflammation, is also implicated in the progression of ... Angiotensin II modulates CD40 expression in vascular smooth muscle cells. *Souza H ... cyclo-oxygenase-2) expression. We conclude that AngII stimulation of vascular cells leads to a ROS-dependent increase in CD40/ ...
  https://www.mendeley.com/research-papers/angiotensin-ii-modulates-cd40-expression-vascular-smooth-muscle-cells/
*  Angiotensin II, human, FAM-labeled
... ; This is a fluorescent (FAM)-labeled Angiotensin II peptide, Abs/Em=494/518 nm. FAM ( ... This is a fluorescent (FAM)-labeled Angiotensin II peptide, Abs/Em=494/518 nm. FAM (carboxyfluorescein) exhibits better ...
  https://www.anaspec.com/products/product.asp?id=30635&productid=14959
*  Angiotensin II Type 1 Receptor peptide (ab176148)
Buy our Angiotensin II Type 1 Receptor peptide. Ab176148 is a blocking peptide for ab124505 and has been validated in BL. Abcam ... Angiotensin II Type 1 Receptor peptide. See all Angiotensin II Type 1 Receptor proteins and peptides. ... Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium ... Blocking - Blocking peptide for Anti-Angiotensin II Type 1 Receptor antibody (ab124505) ...
  http://www.abcam.com/angiotensin-ii-type-1-receptor-peptide-ab176148.html
*  Renal injury from angiotensin II-mediated hypertension. | Hypertension
Angiotensin II (Ang II)-mediated hypertension induces vascular smooth muscle cell hypertrophy and hyperplasia in systemic blood ... Renal injury from angiotensin II-mediated hypertension.. R J Johnson, C E Alpers, A Yoshimura, D Lombardi, P Pritzl, J Floege, ... Renal injury from angiotensin II-mediated hypertension.. R J Johnson, C E Alpers, A Yoshimura, D Lombardi, P Pritzl, J Floege ... Renal injury from angiotensin II-mediated hypertension.. R J Johnson, C E Alpers, A Yoshimura, D Lombardi, P Pritzl, J Floege ...
  http://hyper.ahajournals.org/content/19/5/464