Effects of Poststroke Losartan Versus Captopril Treatment on Myogenic and Endothelial Function in the Cerebrovasculature of...
The effects of captopril, an angiotensin-converting enzyme inhibitor that inhibits AII formation, were compared with those of ... SHRsp capable of developing stroke have an overactive renin-angiotensin system1,6 and high blood aldosterone levels.1 Captopril ... Effects of captopril on the rennin-angiotensin system, oxidative stress, and endothelin in normal and hypertensive rats. ... Poststroke captopril-treated SHRsp (n=5) were 19.7±0.6 weeks old and had an SBP of 258±8 mm Hg, with 31±0.5 days on captopril ...http://stroke.ahajournals.org/content/38/5/1590
IJMS | Free Full-Text | Angiotensin-Converting Enzymes Play a Dominant Role in Fertility | HTML
Moreover, alterations in the expression of angiotensin-converting enzyme-1, angiotensin-converting enzyme-2, and angiotensin- ... An accumulating body of evidence has shown that the renin-angiotensin system is involved in the fertility problems observed in ... However, as a pseudogene in humans, further studies are needed to explore whether the abnormal angiotensin-converting enzyme-3 ... In this review, the relationship between angiotensin-converting enzymes and fertile ability is summarized, and a new procedure ...http://mdpi.com/1422-0067/14/10/21071/htm
Antiatherosclerotic Effects of the Angiotensin-Converting Enzyme Inhibitors Captopril and Fosinopril in Hypercholesterolemic...
Captopril potentiated bradykinin- and inhibited angiotensin I-induced contractions only in arteries with intact NO synthesis. ... Angiotensin, converting enzyme inhibitors, Atherosclerosis, Captopril, Cholesterol, Fosinopril, lntimal thickening, Minipigs ... Angiotensin-converting enzyme (ACE) is as a key enzyme in the renin-angiotensin system involved in the regulation of blood ... We evaluated the two angiotensin-converting enzyme (ACE) inhibitors captopril and fosinopril with regard to possible ...http://liu.diva-portal.org/smash/record.jsf?pid=diva2:543027
Comparative Effects of a Novel Angiotensin-Converting Enzyme Inhibitor versus Captopril on Plasma Angiotensins after Myocardial...
... has molecular characteristics similar to angiotensin-converting enzyme (ACE) inhibitors of the sulfhydryl subclass. To assess ... Comparative Effects of a Novel Angiotensin-Converting Enzyme Inhibitor versus Captopril on Plasma Angiotensins after Myocardial ... Administration of either captopril or TBTIF reversed the increases in plasma angiotensins. Interestingly, the levels of plasma ... we performed a comparative analysis of the effect of TBTIF versus captopril on the circulating levels of angiotensin (Ang) ...http://www.biomedsearch.com/nih/Comparative-Effects-Novel-Angiotensin-Converting/25171296.html
Prevention of genetic hypertension by early treatment of spontaneously hypertensive rats with the angiotensin converting enzyme...
This effect was associated with decreased central responses to angiotensin I and II. Our data suggest that captopril may ... Mating pairs of SHR were treated with captopril, and their pups were maintained on captopril until experimentation. Some ... with the exception that captopril-treated rats showed lesser pressor responses to angiotensin I. Early administration of ... with the angiotensin converting enzyme inhibitor captopril could permanently alter the course of hypertension. ...http://hyper.ahajournals.org/content/22/2/139
Lirias: Acute changes in the renin-angiotensin-aldosterone system, catecholamines and prostaglandins during captopril in man
Captopril provoked increases in plasma renin activity, active and total plasma renin concentration and angiotensin I; decreases ... Acute changes in the renin-angiotensin-aldosterone system, catecholamines and prostaglandins during captopril in man. ... The acute hypotensive effect of 25 mg captopril was investigated in 26 hypertensive patients (11 essential and 15 with renal ... angiotensin I and II, aldosterone, kininase II, catecholamines and prostaglandins. ...https://lirias.kuleuven.be/handle/123456789/23832
Angiotensins II and III prevent captopril-induced renin release in the rat - DRO
Angiotensin II. Angiotensin III. Animals. Blood Pressure. Captopril. Female. Norepinephrine. Rats. Rats, Inbred Strains. Renin ... Angiotensins II and III prevent captopril-induced renin release in the rat. Moldenhauer, G. K., Smith, M. D., Di Nicolantonio, ... Angiotensins II and III prevent captopril-induced renin release in the rat ... R., Doyle, A. E. and Morgan, T. O. 1988, Angiotensins II and III prevent captopril-induced renin release in the rat, Clinical ...http://dro.deakin.edu.au/view/DU:30075224
Newer Insights into the Biochemical Physiology of the Renin-Angiotensin System: Role of Angiotensin-(1-7), Angiotensin...
Knowledge of the mechanisms by which the rennin-angiotensin system contributes to cardiovascular pathology continues to advance ... Effects of captopril related to increased levels of prostacyclin and angiotensin-(1-7) in essential hypertension. J Hypertens. ... A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ Res. 2000 ... Newer Insights into the Biochemical Physiology of the Renin-Angiotensin System: Role of Angiotensin-(1-7), Angiotensin ...https://link.springer.com/chapter/10.1007/978-1-4419-0528-4_2
Natural product - Wikipedia
These include the angiotensin-converting enzyme inhibitor captopril. Captopril is based on the peptidic bradykinin potentiating ... was a lead in the development of the antihypertensive agents cilazapril and captopril. Also, echistatin, a disintegrin from the ...https://en.wikipedia.org/wiki/Natural_product
Effects of Neutral Endopeptidase Inhibition and Combined Angiotensin Converting Enzyme and Neutral Endopeptidase Inhibition on...
1981) Opposite effects of captopril on angiotensin I-converting enzyme 'activity' and 'concentration'; relation between enzyme ... angiotensin converting enzyme. Ang I. angiotensin I. Ang II. angiotensin II. ANOVA. analysis of variance. ANP. atrial ... 1993) Angiotensin-converting enzyme inhibitors in the treatment of heart failure. in The Renin-Angiotensin System, eds ... 1993) Angiotensin-converting enzyme inhibitors in the treatment of essential hypertension. in The Renin-Angiotensin System, eds ...http://jpet.aspetjournals.org/content/287/2/567
1992) Anesthesia alters pulmonary vasoregulation by angiotensin II and captopril. J Appl Physiol 72:636-642. ... 1997) Effects of the angiotensin converting enzyme (ACE) inhibitor, captopril, on the cardiovascular, endocrine and renal ... because removal of endogenous ANG II levels by administration of the angiotensin-converting enzyme inhibitor captopril to ... 1983) The effects of anesthesia and mode of delivery on the parameters of the renin-angiotensin system. Clin Exp Hypertens 2:83 ...http://ajpregu.physiology.org/content/281/4/R1311
Modulating Effects of Lisinopril on Sildenafil Activity in Pulmonary Arterial Hypertension(PAH)( MELISSA) - Full Text View -...
Allergy or intolerance to captopril or other angiotensin converting enzyme inhibitors. *Systemic systolic blood pressure less ... Angiotensin-Converting Enzyme Inhibitors. Protease Inhibitors. Antihypertensive Agents. Cardiotonic Agents. Protective Agents. ... The broad aim of this investigation is to determine whether the modulating effect of angiotensin converting enzyme inhibition ... Demonstrate whether long-acting angiotensin-converting enzyme inhibitor (ACEI) in Pulmonary Arterial Hypertension (PAH) pts on ...https://clinicaltrials.gov/ct2/show/NCT01181284?term=PAH&rank=6
Table of Contents - September 01, 1995, 26 (3) | Hypertension
Effect of Captopril and Angiotensin II Receptor Blockade on Pressure Natriuresis in Transgenic TGR(mRen-2)27 Rats Volkmar Gross ... Chronic Infusion of Angiotensin II Resets Baroreflex Control of Heart Rate by an Arterial Pressure-Independent Mechanism ... β-Adrenergic, Angiotensin II, and Bradykinin Receptors Enhance Neurotransmission in Human Kidney Lars C. Rump, Christine ... Angiotensin-Converting Enzyme Inhibition and Radial Artery Compliance in Patients With Congestive Heart Failure Cristina ...http://hyper.ahajournals.org/content/26/3
Acta Medica Scandinavica - Volume 210, Issue S652 - January/December 1981 - Wiley Online Library
CAPTOPRIL - AN ORAL ANGIOTENSIN-CONVERTING ENZYME INHIBITOR IN CHF (pages 181-187). Kanu Chatterjee, Jean-Lucien Rouleau and ...http://onlinelibrary.wiley.com/doi/10.1111/joim.1981.210.issue-S652/issuetoc
Table of Contents | Clinical Cancer Research
Captopril, an Angiotensin-Converting Enzyme Inhibitor, Promotes Growth of Immunogenic Tumors in Mice ...http://clincancerres.aacrjournals.org/content/12/13
Patent US20080132992 - Coated implantable medical device - Google Patents
... captopril, enalapril or another angiotensin converting enzyme (ACE) inhibitor; ascorbic acid, alpha tocopherol, superoxide ... wherein the anti-hypertensive bioactive agent is selected from the group consisting of: captopril and enalapril. ... wherein the anti-hypertensive bioactive agent comprises an angiotensin converting enzyme (ACE) inhibitor. ... a second angiotensin converting enzyme (ACE) inhibitor, a free radical scavenger agent, an iron chelator agent, an antioxidant ...http://www.google.ca/patents/US20080132992
Angioedema Incidence in US Veterans Initiating Angiotensin-Converting Enzyme Inhibitors | Hypertension
Safety profiles of the angiotensin converting enzyme inhibitors captopril and enalapril. Am J Med. 1986; 81: 46-50. ... Renin-Angiotensin System. Angioedema Incidence in US Veterans Initiating Angiotensin-Converting Enzyme Inhibitors. Donald R. ... Effects of angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists on mortality and renal outcomes in ... effect of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers. Amer Heart J. 2004; 148: 747-754. ...http://hyper.ahajournals.org/content/51/6/1624
Patent US20050278021 - Coated medical device - Google Patents
... angiotensin converting enzyme inhibitors such as Captopril (available from Squibb), Cilazapril (available from Hoffman-LaRoche ... captopril, enalapril or another angiotensin converting enzyme (ACE) inhibitor; ascorbic acid, alphatocopherol, super-oxide ... captopril, enalapril or another angiotensin converting enzyme (ACE) inhibitor; ascorbic acid, alphatocopherol, superoxide ... Medical devices and methods for local delivery of angiotensin II type 2 receptor antagonists. ...http://www.google.com.au/patents/US20050278021
Patente US7958840 - Method and apparatus for coating of substrates - Google Patentes
... captopril, enalapril or another angiotensin converting enzyme (ACE) inhibitor; angiotensin receptor blockers; enzyme inhibitors ...http://www.google.es/patents/US7958840?dq=flatulence
Altered Inotropic Responsiveness and Gene Expression of Hypertrophied Myocardium With Captopril | Hypertension
... angiotensin II has been shown to directly stimulate activity of the Na+/Ca2+ exchanger38 ; captopril may therefore reduce ... Thus, in the SHR, improved inotropic responsiveness with captopril may be mediated by the captopril-induced increase in V1. It ... 8 We have recently demonstrated that treatment with the angiotensin-converting enzyme (ACE) inhibitor captopril causes a ... Captopril was added to drinking water at a concentration of 2 g/L (CAPRx), which has been shown to be effective in preventing ...http://hyper.ahajournals.org/content/35/6/1203
Matrix metalloproteinase-2 inhibition by temocapril and its important role in peritoneal transport.
Recently, it was reported that captopril, an angiotens ... Recently, it was reported that captopril, an angiotensin- ...http://www.biomedsearch.com/nih/Matrix-metalloproteinase-2-inhibition-by/23013132.html
a amylase enzyme - a amylase enzyme online Wholesalers
Inhibitor Captopril Medicine CAS 62571-86-2 Active Angiotensin-Converting Enzyme ACE Product Name: Captopril Synonyms: acediur; ... Inhibitor Captopril Medicine CAS 62571-86-2 Active Angiotensin-Converting Enzyme ACE ... Inhibitor Captopril Medicine CAS 62571-86-2 Active Angiotensin-Converting Enzyme ACE ...http://www.splicd.com/wholesale-a-amylase-enzyme
Prorenin, Renin, Angiotensinogen, and Angiotensin-Converting Enzyme in Normal and Failing Human Hearts | Circulation
Opposite effects of captopril on angiotensin I-converting enzyme 'activity' and 'concentration': relation between enzyme ... Renin-angiotensin system components in the interstitial fluid of the isolated perfused heart: local production of angiotensin I ... Cardiac renin and angiotensins: uptake from plasma versus in situ synthesis. Hypertension.. 1994;24:37-48. ... Cardiac angiotensin converting enzyme and myocardial fibrosis in the rat. Cardiovasc Res.. 1994;28:1423-1432. ...http://circ.ahajournals.org/content/96/1/220
Effects of Hypertension, Diabetes Mellitus, and Hypercholesterolemia on Endothelin Type B Receptor-Mediated Nitric Oxide...
Antiatherosclerotic effects of the angiotensin-converting enzyme inhibitors captopril and fosinopril in hypercholesterolemic ... It has been shown that angiotensin II increases production of ET-1 in various conditions.28 This suggests that angiotensin II ... angiotensin. Endothelin is a potent vasoconstrictor peptide discovered in cultured porcine endothelial cells.1 Of the 3 ... The systemic renin-angiotensin system has been considered to be normal or suppressed in DM. However, tissue-specific activation ...http://circ.ahajournals.org/content/99/9/1242
Carboxypeptidase A - Wikipedia
Carboxypeptidase A and the target enzyme of Captopril, angiotensin-converting enzyme, have very similar structures, as they ... For example, a drug that treats high blood pressure, Captopril, was designed based on a carboxypeptidase A inhibitor. ... Recent biomedical research on collagenase, enkephlinase, and angiotensin-converting enzyme used carboxypeptidase A for ... lower blood pressure through the renin-angiotensin-aldosterone system. Classified as a metalloexopeptidase, carboxypeptidase A ...https://en.wikipedia.org/wiki/Carboxypeptidase_A